BR0110679A - Derivados anfìfilos macrocìclicos e seus análogos - Google Patents

Derivados anfìfilos macrocìclicos e seus análogos

Info

Publication number
BR0110679A
BR0110679A BR0110679-1A BR0110679A BR0110679A BR 0110679 A BR0110679 A BR 0110679A BR 0110679 A BR0110679 A BR 0110679A BR 0110679 A BR0110679 A BR 0110679A
Authority
BR
Brazil
Prior art keywords
macrocyclic
analogs
derivatives
amphophilic
groups attached
Prior art date
Application number
BR0110679-1A
Other languages
English (en)
Inventor
Raphael Darcy
Lawrence John Penkler
Bart Jan Ravoo
Original Assignee
Univ Dublin
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Dublin filed Critical Univ Dublin
Publication of BR0110679A publication Critical patent/BR0110679A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
    • C08B37/0009—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid alpha-D-Glucans, e.g. polydextrose, alternan, glycogen; (alpha-1,4)(alpha-1,6)-D-Glucans; (alpha-1,3)(alpha-1,4)-D-Glucans, e.g. isolichenan or nigeran; (alpha-1,4)-D-Glucans; (alpha-1,3)-D-Glucans, e.g. pseudonigeran; Derivatives thereof
    • C08B37/0012—Cyclodextrin [CD], e.g. cycle with 6 units (alpha), with 7 units (beta) and with 8 units (gamma), large-ring cyclodextrin or cycloamylose with 9 units or more; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6949—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
    • A61K47/6951—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nanotechnology (AREA)
  • Materials Engineering (AREA)
  • Biotechnology (AREA)
  • Public Health (AREA)
  • Biochemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Biophysics (AREA)
  • Veterinary Medicine (AREA)
  • General Engineering & Computer Science (AREA)
  • Medical Informatics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Epidemiology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Saccharide Compounds (AREA)

Abstract

"DERIVADOS ANFìFILOS MACROCìCLICOS E SEUS ANáLOGOS". Análogos macrocíclicos anfífilos solúveis tendo grupamentos lipófilos ligados a um lado das unidades que formam o macrociclo e grupamentos hidrófilos ligados ao outro lado. Estes derivados macrocíclicos anfífilos têm a capacidade de se auto-agrupar em solvente aquoso formando micelas ou vesículas e podem ser usados como hospedeiros para a solubilização é/ou estabilização de diversos compostos. As modalidades da presente invenção utilizam oligossacarídeos macrocíclicos e de preferência ciclodextrina como os derivados macrocíclicos a serem modificados.
BR0110679-1A 2000-04-28 2001-04-30 Derivados anfìfilos macrocìclicos e seus análogos BR0110679A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IE20000326 2000-04-28
PCT/IE2001/000057 WO2001083564A1 (en) 2000-04-28 2001-04-30 Amphiphilic macrocyclic derivatives and their analogues

Publications (1)

Publication Number Publication Date
BR0110679A true BR0110679A (pt) 2004-04-20

Family

ID=11042603

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0110679-1A BR0110679A (pt) 2000-04-28 2001-04-30 Derivados anfìfilos macrocìclicos e seus análogos

Country Status (8)

Country Link
US (2) US20030092672A1 (pt)
EP (1) EP1287039A1 (pt)
JP (1) JP2003531930A (pt)
CN (1) CN1439023A (pt)
AU (1) AU5503001A (pt)
BR (1) BR0110679A (pt)
CA (1) CA2406823A1 (pt)
WO (1) WO2001083564A1 (pt)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
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US7491690B2 (en) * 2001-11-14 2009-02-17 Northwestern University Self-assembly and mineralization of peptide-amphiphile nanofibers
WO2003070749A2 (en) * 2002-02-15 2003-08-28 Northwestern University Self-assembly of peptide-amphiphile nanofibers under physiological conditions
JP2005518470A (ja) * 2002-02-22 2005-06-23 インサート セラピューティクス インコーポレイテッド 炭水化物−修飾ポリマー組成物及びその使用法
AU2003262760A1 (en) 2002-08-21 2004-03-11 Northwestern University Charged peptide-amphiphile solutions and self-assembled peptide nanofiber networks formed therefrom
AU2002951216A0 (en) * 2002-09-05 2002-09-19 Dbl Australia Pty Ltd Surfactants and lyotropic phases formed therefrom
US7554021B2 (en) * 2002-11-12 2009-06-30 Northwestern University Composition and method for self-assembly and mineralization of peptide amphiphiles
AU2003298647A1 (en) * 2002-11-14 2004-06-15 Claussen, Randal, C. Synthesis and self-assembly of abc triblock bola peptide
EP1606065A4 (en) 2003-02-11 2010-09-29 Univ Northwestern METHOD AND MATERIALS FOR NANOCRYSTALLINE SURFACE COATINGS AND ATTACHMENT OF AMPHIPHILENE PEPTIDE NANO FIBERS THEREOF
FR2861396B1 (fr) * 2003-10-24 2005-12-16 Commissariat Energie Atomique Derives amphiphiles de cyclodextrines,leur procede de preparation et leurs utilisations
EP1696944A4 (en) 2003-12-05 2008-11-05 Univ Northwestern BRANCHED PEPTIDE AMPHIPHILES, RELATED EPITOPES COMPOUNDS AND SELF-ASSOCIATED STRUCTURES THEREOF
US7544661B2 (en) * 2003-12-05 2009-06-09 Northwestern University Self-assembling peptide amphiphiles and related methods for growth factor delivery
US7851457B2 (en) 2004-01-29 2010-12-14 Innovative Biologics, Inc. β-Cyclodextrin derivatives
WO2006083678A2 (en) 2005-01-28 2006-08-10 Pinnacle Pharmaceuticals, Inc. β-CYCLODEXTRIN DERIVATIVES AS ANTIBACTERIAL AGENTS
WO2006096614A2 (en) * 2005-03-04 2006-09-14 Northwestern University Angiogenic heparin binding peptide amphiphiles
FR2903987B1 (fr) * 2006-07-21 2012-12-21 Centre Nat Rech Scient Nouveaux derives de cyclodextrines amphiphiles, leur utilisation dans les domaines pharmaceutiques,cosmetiques, alimentaires et leur application a la production de nouveaux nanosystemes
FR2907455A1 (fr) * 2006-10-18 2008-04-25 Commissariat Energie Atomique Oligosaccharides cycliques,notamment derives de cyclodextrines amphiphiles,substitues par un ou plusieurs groupements polycycles naturels,tels que les triterpenoides.
FR2908414B1 (fr) * 2006-11-13 2012-01-20 Centre Nat Rech Scient Immobilisation de proteines membranaires sur un support par l'intermediaire d'une molecule amphiphile
US8076295B2 (en) * 2007-04-17 2011-12-13 Nanotope, Inc. Peptide amphiphiles having improved solubility and methods of using same
GB0812226D0 (en) 2008-07-04 2008-08-13 Univ Dublin A macrocyclic derivative and assemblies formed therefrom
US8207264B2 (en) 2008-07-11 2012-06-26 Tyco Healthcare Group Lp Functionalized inclusion complexes as crosslinkers
MX2011010780A (es) * 2009-04-13 2011-10-28 Univ Northwestern Andamios novedosos basados en peptido para la regeneracion de cartilagos y metodos para su uso.
ES2530049T3 (es) 2009-05-18 2015-02-26 Sigmoid Pharma Limited Composición que comprende gotas de aceite
JP6346400B2 (ja) * 2012-08-15 2018-06-20 日本製紙株式会社 溶解パルプ
WO2014058438A1 (en) * 2012-10-12 2014-04-17 Empire Technology Development Llc Paints and coatings containing cyclodextrin additives
WO2015048897A1 (en) * 2013-10-01 2015-04-09 Uti Limited Partnership Amphiphilic cyclodextrin-based glycodendrimers
AU2015390471A1 (en) * 2015-04-08 2017-11-09 John KLASSEN Pharmaceutical compositions of polyanionic and non-ionic cyclodextrin-based dendrimers and uses thereof
EP3359578A4 (en) * 2015-10-07 2019-05-15 UTI Limited Partnership MULTIFUNCTIONAL POLYANIONIC CYCLODEXTRINDDRIMERE
US20190321487A1 (en) 2016-12-14 2019-10-24 University College Cork - National University Of Ireland, Cork Cyclodextrin conjugates
MX2019006868A (es) * 2016-12-16 2019-09-23 Du Pont Derivados de polisacáridos anfifílicos y composiciones que los comprenden.
CN118178673B (zh) * 2024-04-07 2024-11-05 铭畅生物医药南通有限公司 一种唾液酸酯环糊精包合物及其制备方法和用途
CN118490657B (zh) * 2024-05-15 2025-01-17 仁合熙德隆药业有限公司 瑞戈非尼片及其制备方法

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JPS5461289A (en) * 1977-10-24 1979-05-17 Iwao Tabuse Method of making polystyrene base polymer containing cyclodextrine derivative
US4258180A (en) * 1979-11-05 1981-03-24 American Cyanamid Company C6-Modified cyclodextrin sulfate salts as complement inhibitors
US4920214A (en) * 1986-04-16 1990-04-24 American Maize-Products Company Process for producing modified cyclodextrins
MY106598A (en) * 1988-08-31 1995-06-30 Australian Commercial Res & Development Ltd Compositions and methods for drug delivery and chromatography.
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AU639373B2 (en) * 1990-10-22 1993-07-22 Unilever Plc Cosmetic composition
JP3069668B2 (ja) * 1991-04-08 2000-07-24 工業技術院長 エーテル化シクロデキストリンポリマー
FR2692168B1 (fr) * 1992-06-16 1995-03-24 Centre Nat Rech Scient Préparation et utilisation de nouveaux systèmes colloïdaux dispersibles à base de cyclodextrine, sous forme de nanosphères.
DE4428654A1 (de) * 1994-08-12 1996-02-15 Consortium Elektrochem Ind Wasserlösliche Cyclodextrinderivate mit lipophilen Substituenten und Verfahren zu ihrer Herstellung
FR2736056B1 (fr) * 1995-06-29 1997-08-08 Commissariat Energie Atomique Derives de cyclodextrines, leur preparation et leur utilisation pour incorporer des molecules hydrophobes dans des systemes de tensioactifs organises
DE19612768A1 (de) * 1996-03-29 1997-10-02 Basf Ag Cyclodextringruppen enthaltende Polymere, Verfahren zu ihrer Herstellung und ihre Verwendung
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US6048736A (en) * 1998-04-29 2000-04-11 Kosak; Kenneth M. Cyclodextrin polymers for carrying and releasing drugs

Also Published As

Publication number Publication date
WO2001083564A1 (en) 2001-11-08
US20060148756A1 (en) 2006-07-06
US20030092672A1 (en) 2003-05-15
CN1439023A (zh) 2003-08-27
JP2003531930A (ja) 2003-10-28
AU5503001A (en) 2001-11-12
EP1287039A1 (en) 2003-03-05
CA2406823A1 (en) 2001-11-08
US7786095B2 (en) 2010-08-31

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Legal Events

Date Code Title Description
B11A Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing
B11Y Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette]