BR0116123A - Carbazóis antitumorais - Google Patents

Carbazóis antitumorais

Info

Publication number
BR0116123A
BR0116123A BR0116123-7A BR0116123A BR0116123A BR 0116123 A BR0116123 A BR 0116123A BR 0116123 A BR0116123 A BR 0116123A BR 0116123 A BR0116123 A BR 0116123A
Authority
BR
Brazil
Prior art keywords
carbazoles
antitumor
medicine
relates
carbazois
Prior art date
Application number
BR0116123-7A
Other languages
English (en)
Inventor
Murray Herbert Gibson Munro
John Wilson Blunt
Sylvia Urban
Dolores Garcia Gravalos
Original Assignee
Pharma Mar Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharma Mar Sa filed Critical Pharma Mar Sa
Publication of BR0116123A publication Critical patent/BR0116123A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C07D209/80—[b, c]- or [b, d]-condensed
    • C07D209/82—Carbazoles; Hydrogenated carbazoles
    • C07D209/88—Carbazoles; Hydrogenated carbazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Urology & Nephrology (AREA)
  • Dermatology (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

"CARBAZóIS ANTITUMORAIS". A invenção provê um composto da fórmula (I). Esta invenção refere-se a compostos heterocíclicos. Ela refere-se ainda a métodos para sua preparação, composições contendo-os e seu uso como um medicamento, particularmente como medicamento para o tratamento e profilaxia de câncer.
BR0116123-7A 2000-12-13 2001-12-13 Carbazóis antitumorais BR0116123A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0030417.0A GB0030417D0 (en) 2000-12-13 2000-12-13 An anticancer lead compound isolated from a New Zealand ascidian
PCT/GB2001/005523 WO2002048107A1 (en) 2000-12-13 2001-12-13 Antitumoral carbazoles

Publications (1)

Publication Number Publication Date
BR0116123A true BR0116123A (pt) 2003-10-14

Family

ID=9905016

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0116123-7A BR0116123A (pt) 2000-12-13 2001-12-13 Carbazóis antitumorais

Country Status (11)

Country Link
US (1) US7135494B2 (pt)
EP (1) EP1349837A1 (pt)
JP (1) JP2004518650A (pt)
AU (1) AU2002217266A1 (pt)
BR (1) BR0116123A (pt)
CA (1) CA2431107A1 (pt)
GB (1) GB0030417D0 (pt)
IL (1) IL156372A0 (pt)
MX (1) MXPA03005374A (pt)
NZ (1) NZ526399A (pt)
WO (1) WO2002048107A1 (pt)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010005870A1 (en) * 2008-07-08 2010-01-14 Trustees Of Dartmouth College Bis-carbazole dna intercalating agents for antitumor therapy
US8530496B2 (en) 2008-07-08 2013-09-10 Trustees Of Dartmouth College Compositions and methods for treating cancer
US8975274B2 (en) 2011-09-20 2015-03-10 Trustees Of Dartmouth College Compositions and methods for treating cancer
SI2902029T1 (sl) 2012-09-25 2018-11-30 Chugai Seiyaku Kabushiki Kaisha Inhibitor ret
WO2015163448A1 (ja) 2014-04-25 2015-10-29 中外製薬株式会社 ４環性化合物を高用量含有する製剤
CA2973857C (en) 2015-01-16 2023-11-07 Chugai Seiyaku Kabushiki Kaisha Combination drug
HRP20231233T1 (hr) 2017-04-27 2024-01-19 Pharma Mar, S.A. Antitumorski spojevi
EP4316598B1 (en) 2018-06-29 2025-06-18 Chugai Seiyaku Kabushiki Kaisha Pharmaceutical composition comprising a poorly soluble basic agent
BR112021001145A2 (pt) 2018-09-04 2021-04-20 Chugai Seiyaku Kabushiki Kaisha método para a produção de composto tetracíclico
WO2023220558A1 (en) * 2022-05-09 2023-11-16 Institute For Cancer Research D/B/A The Research Institute Of Fox Chase Cancer Center Combination of curaxins and immune checkpoint inhibitors for treating cancer

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0331257A (ja) * 1989-06-28 1991-02-12 Kissei Pharmaceut Co Ltd インドール誘導体の製造方法
EP0586608A1 (en) 1991-05-29 1994-03-16 Pfizer Inc. Tricyclic polyhydroxylic tyrosine kinase inhibitors
JPH08157475A (ja) * 1994-11-29 1996-06-18 Kissei Pharmaceut Co Ltd １−ヒドロキシインドール誘導体

Also Published As

Publication number Publication date
US7135494B2 (en) 2006-11-14
IL156372A0 (en) 2004-01-04
CA2431107A1 (en) 2002-06-20
WO2002048107A1 (en) 2002-06-20
AU2002217266A1 (en) 2002-06-24
MXPA03005374A (es) 2004-03-26
JP2004518650A (ja) 2004-06-24
NZ526399A (en) 2005-02-25
EP1349837A1 (en) 2003-10-08
US20040072890A1 (en) 2004-04-15
GB0030417D0 (en) 2001-01-24

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE 7A. E 8A. ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 DA RPI 2021 DE 29/09/2009.