BR0116151A - Uso de fator de coagulação ativada vii para tratamento de sangramentos principais induzidos na terapia trombolìtica - Google Patents

Uso de fator de coagulação ativada vii para tratamento de sangramentos principais induzidos na terapia trombolìtica

Info

Publication number
BR0116151A
BR0116151A BR0116151-2A BR0116151A BR0116151A BR 0116151 A BR0116151 A BR 0116151A BR 0116151 A BR0116151 A BR 0116151A BR 0116151 A BR0116151 A BR 0116151A
Authority
BR
Brazil
Prior art keywords
induced
factor vii
bleeds
coagulation factor
activated coagulation
Prior art date
Application number
BR0116151-2A
Other languages
English (en)
Inventor
Cord Skamira
Jean Marie Stassen
Gerhard Heusel
Wolfgang Wienen
Original Assignee
Boehringer Ingelheim Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Pharma filed Critical Boehringer Ingelheim Pharma
Publication of BR0116151A publication Critical patent/BR0116151A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/482—Serine endopeptidases (3.4.21)
    • A61K38/4846—Factor VII (3.4.21.21); Factor IX (3.4.21.22); Factor Xa (3.4.21.6); Factor XI (3.4.21.27); Factor XII (3.4.21.38)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

"USO DE FATOR DE COAGULAçãO ATIVADA VII PARA TRATAMENTO DE SANGRAMENTOS PRINCIPAIS INDUZIDOS NA TERAPIA TROMBOLìTICA". A invenção refere-se a grandes sangramentos induzidos por terapia trombolítica/fibrinolítica, incluindo hemorragias intracraniais que são tratadas, administrando ao indivíduo sofrendo de tais sangramentos, uma quantidade eficaz de fator VII (VIIa) ativado de coagulação ou um derivado funcional do mesmo.
BR0116151-2A 2000-12-21 2001-12-20 Uso de fator de coagulação ativada vii para tratamento de sangramentos principais induzidos na terapia trombolìtica BR0116151A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP00128252A EP1216709A1 (en) 2000-12-21 2000-12-21 Use of activated coagulation factor VII for treating thrombolytic therapy-induced major bleedings
PCT/EP2001/015132 WO2002049665A2 (en) 2000-12-21 2001-12-20 Use of activated coagulation factor vii for treating thrombolytic therapy-induced major bleedings

Publications (1)

Publication Number Publication Date
BR0116151A true BR0116151A (pt) 2003-10-21

Family

ID=8170769

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0116151-2A BR0116151A (pt) 2000-12-21 2001-12-20 Uso de fator de coagulação ativada vii para tratamento de sangramentos principais induzidos na terapia trombolìtica

Country Status (25)

Country Link
US (2) US20040087502A1 (pt)
EP (2) EP1216709A1 (pt)
JP (1) JP2004516273A (pt)
KR (1) KR20030063454A (pt)
CN (1) CN1482919A (pt)
AT (1) ATE353666T1 (pt)
AU (2) AU2638602A (pt)
BR (1) BR0116151A (pt)
CA (1) CA2431986A1 (pt)
CY (1) CY1106363T1 (pt)
CZ (1) CZ300670B6 (pt)
DE (1) DE60126650T2 (pt)
DK (1) DK1343523T3 (pt)
EC (1) ECSP034647A (pt)
ES (1) ES2280429T3 (pt)
HU (1) HUP0302574A3 (pt)
IL (1) IL155886A0 (pt)
MX (1) MXPA03005641A (pt)
NZ (1) NZ549850A (pt)
PL (1) PL205878B1 (pt)
PT (1) PT1343523E (pt)
RU (1) RU2286796C2 (pt)
SI (1) SI1343523T1 (pt)
WO (1) WO2002049665A2 (pt)
ZA (1) ZA200304140B (pt)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE602005016406D1 (de) * 2004-06-21 2009-10-15 Novo Nordisk Healthcare Ag Faktor viia oder faktor viia äquivaltenen zur prävention oder abschwächung des wachstums von hämorrhagien und/oder der ödemerzeugung nach intrazerebraler hämorrhagie (ich)
RU2396086C2 (ru) * 2004-09-10 2010-08-10 Фармаоригин Апс Способы лечения трахеального, бронхиального или альвеолярного кровотечения или кровохарканья
JP2009501188A (ja) * 2005-07-15 2009-01-15 ノボ ノルディスク ヘルス ケア アーゲー 抗血小板療法で治療される患者における脳内出血（ＩＣＨ）後の出血増大及び／又は浮腫形成を予防又は軽減するための第ＶＩＩａ因子又は第ＶＩＩａ因子等価物の使用
JP2011509978A (ja) 2008-01-18 2011-03-31 ノボ ノルディスク ヘルス ケア アーゲー 選択されたＩＣＨ患者亜集団における脳内出血（ＩＣＨ）後の出血拡大、及び／又は浮腫生成の予防又は減弱のための、第ＶＩＩａ因子又は第ＶＩＩａ因子等価物の使用
RU2552339C1 (ru) * 2014-02-19 2015-06-10 Общество с ограниченной ответственностью фирма "Технология-Стандарт" Способ профилактики кровотечений, вызванных применением стрептокиназы, в эксперименте

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4382082A (en) * 1980-12-18 1983-05-03 Uop Inc. Recovery of cobalt values by absorption from ammoniacal solution
ZA862768B (en) * 1985-04-17 1986-12-30 Zymogenetics Inc Expression of factor vii and ix activities in mammalian cells
US5374617A (en) * 1992-05-13 1994-12-20 Oklahoma Medical Research Foundation Treatment of bleeding with modified tissue factor in combination with FVIIa
US5846517A (en) * 1996-09-11 1998-12-08 Imarx Pharmaceutical Corp. Methods for diagnostic imaging using a renal contrast agent and a vasodilator
WO1998058661A1 (en) * 1997-06-23 1998-12-30 Novo Nordisk A/S Use of fviia for the treatment of bleedings in patients with a normal blood clotting cascade and normal platelet function

Also Published As

Publication number Publication date
IL155886A0 (en) 2003-12-23
US20080286259A1 (en) 2008-11-20
CA2431986A1 (en) 2002-06-27
ES2280429T3 (es) 2007-09-16
WO2002049665A3 (en) 2002-09-26
EP1216709A1 (en) 2002-06-26
EP1343523A2 (en) 2003-09-17
WO2002049665A2 (en) 2002-06-27
CZ300670B6 (cs) 2009-07-15
ECSP034647A (es) 2003-07-25
CZ20031743A3 (cs) 2003-11-12
ATE353666T1 (de) 2007-03-15
EP1343523B1 (en) 2007-02-14
CN1482919A (zh) 2004-03-17
RU2003122362A (ru) 2005-02-10
ZA200304140B (en) 2004-04-22
HUP0302574A2 (hu) 2003-10-28
US20040087502A1 (en) 2004-05-06
KR20030063454A (ko) 2003-07-28
DE60126650D1 (de) 2007-03-29
RU2286796C2 (ru) 2006-11-10
SI1343523T1 (sl) 2007-04-30
PL361855A1 (en) 2004-10-04
CY1106363T1 (el) 2011-10-12
AU2638602A (en) 2002-07-01
AU2002226386B2 (en) 2005-12-22
DE60126650T2 (de) 2007-10-31
JP2004516273A (ja) 2004-06-03
NZ549850A (en) 2008-04-30
DK1343523T3 (da) 2007-04-10
PT1343523E (pt) 2007-03-30
HUP0302574A3 (en) 2010-01-28
MXPA03005641A (es) 2004-12-03
PL205878B1 (pl) 2010-06-30

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Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B11E Dismissal acc. art. 34 of ipl - requirements for examination incomplete
B11T Dismissal of application maintained [chapter 11.20 patent gazette]