BR0209234A - Polinucleotìdeo, vetor de expressão recombinante, polipeptìdeo, célula, e, métodos de produzir o polipeptìdeo e de identificar compostos que afetam a função enzimática da peptidilarginina deiminase 6 - Google Patents

Polinucleotìdeo, vetor de expressão recombinante, polipeptìdeo, célula, e, métodos de produzir o polipeptìdeo e de identificar compostos que afetam a função enzimática da peptidilarginina deiminase 6

Info

Publication number
BR0209234A
BR0209234A BR0209234-4A BR0209234A BR0209234A BR 0209234 A BR0209234 A BR 0209234A BR 0209234 A BR0209234 A BR 0209234A BR 0209234 A BR0209234 A BR 0209234A
Authority
BR
Brazil
Prior art keywords
polypeptide
polynucleotide
affect
cell
producing
Prior art date
Application number
BR0209234-4A
Other languages
English (en)
Inventor
Jan Albert Gossen
Paul Van Den Boogaart
Original Assignee
Akzo Nobel Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akzo Nobel Nv filed Critical Akzo Nobel Nv
Publication of BR0209234A publication Critical patent/BR0209234A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

"POLINUCLEOTìDEO, VETOR DE EXPRESSãO RECOMBINANTE, POLIPEPTìDEO, CéLULA, E, MéTODOS DE PRODUZIR O POLIPEPTìDEO E DE IDENTIFICAR COMPOSTOS QUE AFETAM A FUNçãO ENZIMáTICA DA PEPTIDILARGININA DEIMINASE 6". Proporciona-se uma seq³ência de ácido nucleotídico que codifica uma peptidilarginina deiminase 6. Verifica-se que o gene é expresso apenas em gónadas e pode ser usado como alvo para contracepção masculina e feminina. Sua proteína codificada pode ser usada para selecionar moduladores de baixo peso molecular da atividade de enzima.
BR0209234-4A 2001-05-03 2002-04-25 Polinucleotìdeo, vetor de expressão recombinante, polipeptìdeo, célula, e, métodos de produzir o polipeptìdeo e de identificar compostos que afetam a função enzimática da peptidilarginina deiminase 6 BR0209234A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP01201601 2001-05-03
PCT/EP2002/004552 WO2002090531A2 (en) 2001-05-03 2002-04-25 Peptidylarginine deiminase 6

Publications (1)

Publication Number Publication Date
BR0209234A true BR0209234A (pt) 2004-06-15

Family

ID=8180238

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0209234-4A BR0209234A (pt) 2001-05-03 2002-04-25 Polinucleotìdeo, vetor de expressão recombinante, polipeptìdeo, célula, e, métodos de produzir o polipeptìdeo e de identificar compostos que afetam a função enzimática da peptidilarginina deiminase 6

Country Status (14)

Country Link
US (2) US7501273B2 (pt)
EP (1) EP1387890B1 (pt)
JP (1) JP4142953B2 (pt)
CN (1) CN100523196C (pt)
AT (1) ATE345390T1 (pt)
AU (1) AU2002304693B2 (pt)
BR (1) BR0209234A (pt)
CA (1) CA2445781A1 (pt)
DE (1) DE60216073T2 (pt)
DK (1) DK1387890T3 (pt)
ES (1) ES2274977T3 (pt)
IL (2) IL158223A0 (pt)
MX (1) MXPA03010052A (pt)
WO (1) WO2002090531A2 (pt)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT1573022E (pt) 2001-04-10 2011-08-23 Agensys Inc Ácido nucleico e proteína correspondente intitulada 184p1e2, utilizadas para o tratamento e detecção de cancro
WO2004063347A2 (en) * 2003-01-10 2004-07-29 University Of Virginia Patent Foundation Epad, an oocyte specific protein
CA2555199A1 (en) * 2004-02-04 2005-08-18 Yokohama City University Peptidylarginine deiminase 4 inhibitor
WO2006058043A2 (en) * 2004-11-23 2006-06-01 University Of Virginia Patent Foundation Contraceptive vaccines for dogs and cats based on egg membrane antigens
CN103476944B (zh) * 2011-03-25 2016-01-20 艾尔玛可科学（苏格兰）有限公司 荧光寿命表观遗传学测定
CN110426514B (zh) * 2019-08-28 2023-05-12 苏州新格诺康生物技术有限公司 肽酰基精氨酸脱亚胺酶(pad)的测活法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001053339A2 (en) * 2000-01-20 2001-07-26 University Of Virginia Patent Foundation Egg specific surface proteins
AU2002255478A1 (en) * 2001-01-10 2002-09-12 Pe Corporation (Ny) Kits, such as nucleic acid arrays, comprising a majority of human exons or transcripts, for detecting expression and other uses thereof
WO2003010327A2 (en) * 2001-02-21 2003-02-06 Curagen Corporation Novel proteins and nucleic acids encoding same

Also Published As

Publication number Publication date
CN1571842A (zh) 2005-01-26
US7501273B2 (en) 2009-03-10
ATE345390T1 (de) 2006-12-15
JP2004524855A (ja) 2004-08-19
CA2445781A1 (en) 2002-11-14
WO2002090531A2 (en) 2002-11-14
US20040137598A1 (en) 2004-07-15
DE60216073D1 (de) 2006-12-28
EP1387890B1 (en) 2006-11-15
ES2274977T3 (es) 2007-06-01
EP1387890A2 (en) 2004-02-11
MXPA03010052A (es) 2004-04-02
DK1387890T3 (da) 2007-02-26
AU2002304693B2 (en) 2007-01-25
DE60216073T2 (de) 2007-03-15
US20090162915A1 (en) 2009-06-25
JP4142953B2 (ja) 2008-09-03
IL158223A (en) 2009-08-03
IL158223A0 (en) 2004-05-12
CN100523196C (zh) 2009-08-05
WO2002090531A3 (en) 2003-07-24

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Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A(S) 9A ANUIDADE(S)

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2103 DE 26/04/2011.