BR0212214A - Base livre de clindamicina cristalina - Google Patents

Base livre de clindamicina cristalina

Info

Publication number
BR0212214A
BR0212214A BR0212214-6A BR0212214A BR0212214A BR 0212214 A BR0212214 A BR 0212214A BR 0212214 A BR0212214 A BR 0212214A BR 0212214 A BR0212214 A BR 0212214A
Authority
BR
Brazil
Prior art keywords
free base
crystalline
clindamycin free
crystalline clindamycin
clindamycin
Prior art date
Application number
BR0212214-6A
Other languages
English (en)
Inventor
Robert S Chao
Michael Hawley
Lisa M Reeder
Donald P Jones
Original Assignee
Pharmacia Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia Corp filed Critical Pharmacia Corp
Publication of BR0212214A publication Critical patent/BR0212214A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
    • C07H13/10—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals directly attached to heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/14—Acyclic radicals, not substituted by cyclic structures attached to a sulfur, selenium or tellurium atom of a saccharide radical
    • C07H15/16—Lincomycin; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/26—Acyclic or carbocyclic radicals, substituted by hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

"BASE LIVRE DE CLINDAMICINA CRISTALINA". A droga antibiótica clindamicina é fornecida como uma base livre cristalina. Três formas polimórfica/pseudopolimórfica de base livre de clindamicina cristalina são reveladas. São também fornecidas composições farmacêuticas que compreendem a base livre de clindamicina, cristalina. São também fornecidos os processos para a preparação de base livre de clindamicina cristalina e composições da mesma, juntamente com métodos para tratar condições médicas com as composições farmacêuticas.
BR0212214-6A 2001-08-28 2002-08-26 Base livre de clindamicina cristalina BR0212214A (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US31537501P 2001-08-28 2001-08-28
US37789202P 2002-05-01 2002-05-01
PCT/US2002/027159 WO2003020736A1 (en) 2001-08-28 2002-08-26 Crystaline clindamycin free base

Publications (1)

Publication Number Publication Date
BR0212214A true BR0212214A (pt) 2004-10-19

Family

ID=26979857

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0212214-6A BR0212214A (pt) 2001-08-28 2002-08-26 Base livre de clindamicina cristalina

Country Status (13)

Country Link
US (4) US20030073647A1 (pt)
EP (1) EP1421093B1 (pt)
JP (1) JP2005504785A (pt)
AR (1) AR037654A1 (pt)
AT (1) ATE298758T1 (pt)
BR (1) BR0212214A (pt)
CA (1) CA2458644A1 (pt)
DE (1) DE60204897T2 (pt)
ES (1) ES2243763T3 (pt)
MX (1) MXPA04001964A (pt)
MY (1) MY134083A (pt)
TW (1) TWI232865B (pt)
WO (1) WO2003020736A1 (pt)

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US6565882B2 (en) * 2000-02-24 2003-05-20 Advancis Pharmaceutical Corp Antibiotic composition with inhibitor
US20020068078A1 (en) 2000-10-13 2002-06-06 Rudnic Edward M. Antifungal product, use and formulation thereof
US6541014B2 (en) * 2000-10-13 2003-04-01 Advancis Pharmaceutical Corp. Antiviral product, use and formulation thereof
AU2003284942A1 (en) * 2002-10-30 2004-06-07 Pharmacia Corporation Oral extended release tablets and methods of making and using the same
EP1613333A1 (en) * 2003-04-04 2006-01-11 Pharmacia Corporation Oral extended release compressed tablets of multiparticulates
WO2005009365A2 (en) 2003-07-21 2005-02-03 Advancis Pharmaceutical Corporation Antibiotic product, use and formulation thereof
CA2533358C (en) * 2003-07-21 2014-03-11 Advancis Pharmaceutical Corporation Antibiotic product, use and formulation thereof
AU2004258953B2 (en) * 2003-07-21 2011-02-10 Shionogi, Inc. Antibiotic product, use and formulation thereof
US8758820B2 (en) * 2003-08-11 2014-06-24 Shionogi Inc. Robust pellet
JP2007502294A (ja) 2003-08-12 2007-02-08 アドバンシス ファーマスーティカル コーポレイション 抗生物質製剤、その使用法及び作成方法
US8246996B2 (en) 2003-08-29 2012-08-21 Shionogi Inc. Antibiotic product, use and formulation thereof
JP2007513869A (ja) 2003-09-15 2007-05-31 アドバンシス ファーマスーティカル コーポレイション 抗生物質製剤、その使用法及び作成方法
JP2007517039A (ja) * 2003-12-24 2007-06-28 アドバンシス ファーマスーティカル コーポレイション 変性放出製剤の吸収増強
US8715727B2 (en) 2004-07-02 2014-05-06 Shionogi Inc. Tablet for pulsed delivery
US7976517B2 (en) * 2004-09-30 2011-07-12 Codman & Shurtleff, Inc. Fluid management flow implants of improved occlusion resistance
CN100446774C (zh) * 2005-05-31 2008-12-31 黑龙江龙桂制药有限公司 盐酸克林霉素阴道泡腾片及其制备方法
JP4892915B2 (ja) * 2005-10-04 2012-03-07 大日本印刷株式会社 エパルレスタット製造法
US8357394B2 (en) 2005-12-08 2013-01-22 Shionogi Inc. Compositions and methods for improved efficacy of penicillin-type antibiotics
US8778924B2 (en) 2006-12-04 2014-07-15 Shionogi Inc. Modified release amoxicillin products
US8299052B2 (en) 2006-05-05 2012-10-30 Shionogi Inc. Pharmaceutical compositions and methods for improved bacterial eradication
US7923021B2 (en) * 2007-07-24 2011-04-12 University Of Memphis Research Foundation Local delivery method and composition
EP2313083A1 (en) * 2008-07-22 2011-04-27 Lupin Limited Oral compositions of clindamycin
US10105320B2 (en) * 2013-10-03 2018-10-23 Altria Client Services Soluble fiber lozenge
CN111825729B (zh) * 2020-07-14 2023-08-29 天方药业有限公司 克林霉素磷酸酯的纯化方法
CN112206212B (zh) * 2020-10-16 2023-04-28 海南锦瑞制药有限公司 一种注射用克林霉素磷酸酯的制备方法
CN112569196B (zh) * 2020-12-30 2023-05-12 海南海神同洲制药有限公司 一种克林霉素磷酸酯阴道片及其制备工艺

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Also Published As

Publication number Publication date
ES2243763T3 (es) 2005-12-01
US20050192236A1 (en) 2005-09-01
MY134083A (en) 2007-11-30
US20030073647A1 (en) 2003-04-17
US20030073648A1 (en) 2003-04-17
MXPA04001964A (es) 2004-06-07
EP1421093B1 (en) 2005-06-29
DE60204897T2 (de) 2006-05-11
DE60204897D1 (de) 2005-08-04
WO2003020736A1 (en) 2003-03-13
TWI232865B (en) 2005-05-21
US20030073826A1 (en) 2003-04-17
AR037654A1 (es) 2004-12-01
ATE298758T1 (de) 2005-07-15
JP2005504785A (ja) 2005-02-17
CA2458644A1 (en) 2003-03-13
EP1421093A1 (en) 2004-05-26

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 6A,7A E 8A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2060 DE 29/06/2010.