BR0306730A - Processo e intermediários para agentes antidiabéticos de piridazinona - Google Patents
Processo e intermediários para agentes antidiabéticos de piridazinonaInfo
- Publication number
- BR0306730A BR0306730A BR0306730-0A BR0306730A BR0306730A BR 0306730 A BR0306730 A BR 0306730A BR 0306730 A BR0306730 A BR 0306730A BR 0306730 A BR0306730 A BR 0306730A
- Authority
- BR
- Brazil
- Prior art keywords
- diabetic
- pyridazinone
- intermediates
- antidiabetic agents
- relates
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Diabetes (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Heart & Thoracic Surgery (AREA)
- Neurology (AREA)
- Ophthalmology & Optometry (AREA)
- Neurosurgery (AREA)
- Cardiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
"PROCESSO E INTERMEDIáRIOS PARA AGENTES ANTIDIABéTICOS DE PIRIDAZINONA". A presente invenção refere-se a um processo para preparar inibidores de aldose redutase de piridazinona que são úteis na prevenção e/ou tratamento de complicações diabéticas tais como neuropatia diabética, retinopatia diabética, nefropatia diabética, cardiomiopatia diabética, microangiopatia diabética e macroangiopatia diabética nos mamíferos. A invenção também refere-se a novos intermediários úteis na preparação daqueles inibidores de aldose redutase.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US34767902P | 2002-01-09 | 2002-01-09 | |
| PCT/IB2003/000013 WO2003057691A1 (en) | 2002-01-09 | 2003-01-03 | Process and intermediates for pyridazinone antidiabetic agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR0306730A true BR0306730A (pt) | 2004-12-21 |
Family
ID=23364775
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR0306730-0A BR0306730A (pt) | 2002-01-09 | 2003-01-03 | Processo e intermediários para agentes antidiabéticos de piridazinona |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US6759534B2 (pt) |
| EP (1) | EP1463725B1 (pt) |
| JP (1) | JP2005514421A (pt) |
| KR (1) | KR100604502B1 (pt) |
| CN (1) | CN1269814C (pt) |
| AR (1) | AR038267A1 (pt) |
| AT (1) | ATE302201T1 (pt) |
| AU (1) | AU2003200847A1 (pt) |
| BR (1) | BR0306730A (pt) |
| CA (1) | CA2472331A1 (pt) |
| DE (1) | DE60301324T2 (pt) |
| DK (1) | DK1463725T3 (pt) |
| ES (1) | ES2246464T3 (pt) |
| HU (1) | HUP0500031A2 (pt) |
| IL (1) | IL162594A0 (pt) |
| MX (1) | MXPA04005646A (pt) |
| PL (1) | PL371258A1 (pt) |
| PT (1) | PT1463725E (pt) |
| RU (1) | RU2278116C2 (pt) |
| TW (1) | TWI250980B (pt) |
| WO (1) | WO2003057691A1 (pt) |
| ZA (1) | ZA200404798B (pt) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2442476A1 (en) * | 2001-03-30 | 2002-10-10 | Pfizer Products Inc. | Pyridazinone aldose reductase inhibitors |
| CN103333144B (zh) * | 2013-06-17 | 2014-12-10 | 温州大学 | 一种2-硫基-3-卤代苯并呋喃化合物及其合成方法和用途 |
| CN105732552B (zh) * | 2016-04-12 | 2017-12-01 | 天津师范大学 | 2位或3‑位硫代苯并呋喃化合物的制备方法 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3328770A1 (de) * | 1983-08-10 | 1985-02-28 | Basf Ag, 6700 Ludwigshafen | Pyridazinon-derivate, verfahren zu ihrer herstellung und ihre verwendung als fungizide |
| CA2442476A1 (en) * | 2001-03-30 | 2002-10-10 | Pfizer Products Inc. | Pyridazinone aldose reductase inhibitors |
-
2003
- 2003-01-03 HU HU0500031A patent/HUP0500031A2/hu unknown
- 2003-01-03 KR KR1020047010669A patent/KR100604502B1/ko not_active Expired - Fee Related
- 2003-01-03 TW TW092100108A patent/TWI250980B/zh not_active IP Right Cessation
- 2003-01-03 BR BR0306730-0A patent/BR0306730A/pt not_active IP Right Cessation
- 2003-01-03 AT AT03700018T patent/ATE302201T1/de not_active IP Right Cessation
- 2003-01-03 ES ES03700018T patent/ES2246464T3/es not_active Expired - Lifetime
- 2003-01-03 PL PL03371258A patent/PL371258A1/xx not_active Application Discontinuation
- 2003-01-03 PT PT03700018T patent/PT1463725E/pt unknown
- 2003-01-03 MX MXPA04005646A patent/MXPA04005646A/es active IP Right Grant
- 2003-01-03 IL IL16259403A patent/IL162594A0/xx unknown
- 2003-01-03 AU AU2003200847A patent/AU2003200847A1/en not_active Abandoned
- 2003-01-03 WO PCT/IB2003/000013 patent/WO2003057691A1/en not_active Ceased
- 2003-01-03 CA CA002472331A patent/CA2472331A1/en not_active Abandoned
- 2003-01-03 DK DK03700018T patent/DK1463725T3/da active
- 2003-01-03 DE DE60301324T patent/DE60301324T2/de not_active Expired - Fee Related
- 2003-01-03 EP EP03700018A patent/EP1463725B1/en not_active Expired - Lifetime
- 2003-01-03 JP JP2003558006A patent/JP2005514421A/ja not_active Withdrawn
- 2003-01-03 CN CNB038020114A patent/CN1269814C/zh not_active Expired - Fee Related
- 2003-01-03 RU RU2004121026/04A patent/RU2278116C2/ru not_active IP Right Cessation
- 2003-01-07 AR ARP030100032A patent/AR038267A1/es active IP Right Grant
- 2003-01-07 US US10/337,635 patent/US6759534B2/en not_active Expired - Fee Related
-
2004
- 2004-06-17 ZA ZA200404798A patent/ZA200404798B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ZA200404798B (en) | 2006-02-22 |
| DE60301324T2 (de) | 2006-05-24 |
| JP2005514421A (ja) | 2005-05-19 |
| PL371258A1 (en) | 2005-06-13 |
| TW200302098A (en) | 2003-08-01 |
| ES2246464T3 (es) | 2006-02-16 |
| CN1615307A (zh) | 2005-05-11 |
| RU2278116C2 (ru) | 2006-06-20 |
| HUP0500031A2 (hu) | 2005-04-28 |
| CA2472331A1 (en) | 2003-07-17 |
| AR038267A1 (es) | 2005-01-12 |
| RU2004121026A (ru) | 2006-01-10 |
| EP1463725B1 (en) | 2005-08-17 |
| US20030162969A1 (en) | 2003-08-28 |
| TWI250980B (en) | 2006-03-11 |
| EP1463725A1 (en) | 2004-10-06 |
| WO2003057691A1 (en) | 2003-07-17 |
| PT1463725E (pt) | 2005-10-31 |
| ATE302201T1 (de) | 2005-09-15 |
| US6759534B2 (en) | 2004-07-06 |
| AU2003200847A1 (en) | 2003-07-24 |
| IL162594A0 (en) | 2005-11-20 |
| HK1072598A1 (en) | 2005-09-02 |
| CN1269814C (zh) | 2006-08-16 |
| KR20040072710A (ko) | 2004-08-18 |
| KR100604502B1 (ko) | 2006-07-25 |
| MXPA04005646A (es) | 2004-12-06 |
| DE60301324D1 (de) | 2005-09-22 |
| DK1463725T3 (da) | 2005-11-21 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 6O E 7O ANUIDADE. |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2047 DE 30/03/2010. |