BR0310068A - Uso de um ou mais de um composto, combinação, e, composição farmacêutica - Google Patents

Uso de um ou mais de um composto, combinação, e, composição farmacêutica

Info

Publication number
BR0310068A
BR0310068A BR0310068-5A BR0310068A BR0310068A BR 0310068 A BR0310068 A BR 0310068A BR 0310068 A BR0310068 A BR 0310068A BR 0310068 A BR0310068 A BR 0310068A
Authority
BR
Brazil
Prior art keywords
compound
combination
pharmaceutical composition
formula
injury
Prior art date
Application number
BR0310068-5A
Other languages
English (en)
Inventor
Adam J Smolka
Charles E Hammond
Sandeep Gupta
Original Assignee
Merckle Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merckle Gmbh filed Critical Merckle Gmbh
Publication of BR0310068A publication Critical patent/BR0310068A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/538—1,4-Oxazines, e.g. morpholine ortho- or peri-condensed with carbocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/5415—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with carbocyclic ring systems, e.g. phenothiazine, chlorpromazine, piroxicam
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

"USO DE UM OU MAIS DE UM COMPOSTO, COMBINAçãO, E, COMPOSIçãO FARMACêUTICA". A inibição da bomba de próton gástrica em um mamífero é efetuada através do uso de um composto da fórmula (1): em que as variáveis possuem o significado dado na presente descrição. Um composto preferido é o composto da fórmula (2): Este tratamento melhora, diminui, trata ativamente, reverte ou previne qualquer ferida, dano ou lesões da mucosa gástrica, por exemplo lesões da mucosa gástrica e ulceração.
BR0310068-5A 2002-05-17 2003-05-16 Uso de um ou mais de um composto, combinação, e, composição farmacêutica BR0310068A (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US30892802P 2002-05-17 2002-05-17
EP02011081 2002-05-17
PCT/EP2003/005171 WO2003097041A1 (en) 2002-05-17 2003-05-16 Annelated pyrrole compounds as proton pump inhibitors for treating ulcer

Publications (1)

Publication Number Publication Date
BR0310068A true BR0310068A (pt) 2005-03-08

Family

ID=37725454

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0310068-5A BR0310068A (pt) 2002-05-17 2003-05-16 Uso de um ou mais de um composto, combinação, e, composição farmacêutica

Country Status (15)

Country Link
EP (1) EP1505964B1 (pt)
JP (1) JP2006509720A (pt)
CN (1) CN1309383C (pt)
AU (1) AU2003232788B2 (pt)
BR (1) BR0310068A (pt)
CA (1) CA2484238A1 (pt)
DE (1) DE60317661T2 (pt)
ES (1) ES2297204T3 (pt)
MX (1) MXPA04011097A (pt)
NZ (1) NZ536444A (pt)
PT (1) PT1505964E (pt)
RU (1) RU2336872C2 (pt)
UA (1) UA77812C2 (pt)
WO (1) WO2003097041A1 (pt)
ZA (1) ZA200410123B (pt)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10351035A1 (de) * 2003-10-31 2005-05-25 Merckle Gmbh Chemisch Pharmazeutische Fabrik Pharmazeutische Licofelone-Formulierung
PE20070540A1 (es) * 2005-08-30 2007-06-26 Takeda Pharmaceutical Derivados de pirrol como inhibidores de la secrecion acida
WO2007072503A2 (en) * 2005-12-21 2007-06-28 Panacea Biotec Ltd. Combinations for managing inflammation and associated disorders
ES2534772T3 (es) 2008-10-31 2015-04-28 C-A-I-R Biosciences Gmbh Sal de colina y trometamina de licofelona
CN104447490B (zh) * 2014-11-19 2017-06-06 连云港恒运医药有限公司 一种质子泵抑制剂的晶型、制备中间体及其合成方法和医药用途
CN113549079A (zh) 2018-05-25 2021-10-26 正大天晴药业集团股份有限公司 2,3-二氢-1h-吡咯嗪-7-甲酰胺类衍生物及其应用

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4419246A1 (de) * 1994-06-01 1995-12-07 Merckle Gmbh Heteroarylsubstituierte Pyrrolizinverbindungen und deren Anwendung in der Pharmazie
DE4419247A1 (de) * 1994-06-01 1995-12-07 Merckle Gmbh Sulfonylierte Pyrrolizincarbonsäureamide und deren Anwendung in der Pharmazie
SE9500478D0 (sv) * 1995-02-09 1995-02-09 Astra Ab New pharmaceutical formulation and process
ES2247604T3 (es) * 1995-06-12 2006-03-01 G.D. SEARLE & CO. Composiciones que comprenden un inhibidor de ciclooxigenasa-2 y un inhibidor de 5-lipoxigenasa.
US5852033A (en) * 1995-06-29 1998-12-22 Pharma Mar, S.A. Methods of treatment using lamellarin-class alkaloids
KR100447918B1 (ko) * 1996-07-25 2005-09-28 동아제약주식회사 대장을포함한위장관보호작용을갖는플라본및플라바논화합물
HUP0204336A3 (en) * 1999-11-23 2006-01-30 Merckle Gmbh Anti-inflammatory oxo derivatives and hydroxy derivatives of pyrrolizines, and their pharmaceutical use and pharmaceutical compositions containing them their
EP1142889A1 (en) * 2000-04-03 2001-10-10 Pfizer Products Inc. Pyrazole derivatives as anti-inflammatory/analgesic agents

Also Published As

Publication number Publication date
AU2003232788A1 (en) 2003-12-02
JP2006509720A (ja) 2006-03-23
ES2297204T3 (es) 2008-05-01
DE60317661T2 (de) 2008-10-30
RU2336872C2 (ru) 2008-10-27
PT1505964E (pt) 2008-02-28
ZA200410123B (en) 2006-07-26
CA2484238A1 (en) 2003-11-27
WO2003097041A1 (en) 2003-11-27
AU2003232788B2 (en) 2008-10-02
EP1505964A1 (en) 2005-02-16
CN1309383C (zh) 2007-04-11
NZ536444A (en) 2006-12-22
UA77812C2 (en) 2007-01-15
RU2004136994A (ru) 2005-06-10
MXPA04011097A (es) 2005-02-14
CN1652771A (zh) 2005-08-10
EP1505964B1 (en) 2007-11-21
DE60317661D1 (de) 2008-01-03

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B08E Application fees: requirement for complementation of annuity fee

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Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2112 DE 28/06/2011.