PT979244E - Derivados de ciclosporina, sua preparacao e composicoes farmaceuticas que os contem - Google Patents

Derivados de ciclosporina, sua preparacao e composicoes farmaceuticas que os contem

Info

Publication number: PT979244E
Authority: PT; Portugal
Prior art keywords: contain; preparation; pharmaceutical compositions; cyclosporin derivatives; radical
Prior art date: 1997-04-30

Application number

PT98922872T

Other languages

English (en)

Inventor

Serge Mignani

Jean-Claude Barriere

Jean-Christophe Carry

Michel Evers

Bruno Filoche

Georges Bashiardes

Claude Bensoussan

Jean-Christophe Gueguen

Original Assignee

Aventis Pharma Sa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-04-30

Filing date

1998-04-27

Publication date

2005-06-30

1998-04-27 Application filed by Aventis Pharma Sa filed Critical Aventis Pharma Sa

2005-06-30 Publication of PT979244E publication Critical patent/PT979244E/pt

Links

PMATZTZNYRCHOR-CGLBZJNRSA-N Cyclosporin A Chemical class CC[C@@H]1NC(=O)[C@H]([C@H](O)[C@H](C)C\C=C\C)N(C)C(=O)[C@H](C(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](C(C)C)NC(=O)[C@H](CC(C)C)N(C)C(=O)CN(C)C1=O PMATZTZNYRCHOR-CGLBZJNRSA-N 0.000 title abstract 2
239000008194 pharmaceutical composition Substances 0.000 title 1
208000005074 Retroviridae Infections Diseases 0.000 abstract 1
238000011321 prophylaxis Methods 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
238000011282 treatment Methods 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/64—Cyclic peptides containing only normal peptide links
- C07K7/645—Cyclosporins; Related peptides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Virology (AREA)
Molecular Biology (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Immunology (AREA)
Biophysics (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Biochemistry (AREA)
Genetics & Genomics (AREA)
AIDS & HIV (AREA)
Tropical Medicine & Parasitology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)

PT98922872T 1997-04-30 1998-04-27 Derivados de ciclosporina, sua preparacao e composicoes farmaceuticas que os contem PT979244E (pt)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
FR9705351A FR2762843B1 (fr)	1997-04-30	1997-04-30	Nouveaux derives de cyclosporine, leur preparation et les compositions pharmaceutiques qui les contiennent

Publications (1)

Publication Number	Publication Date
PT979244E true PT979244E (pt)	2005-06-30

Family

ID=9506467

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PT98922872T PT979244E (pt)	1997-04-30	1998-04-27	Derivados de ciclosporina, sua preparacao e composicoes farmaceuticas que os contem

Country Status (13)

Country	Link
US (1)	US5977067A (pt)
EP (1)	EP0979244B1 (pt)
JP (1)	JP2001524105A (pt)
AT (1)	ATE290015T1 (pt)
AU (1)	AU7535798A (pt)
DE (1)	DE69829175T2 (pt)
ES (1)	ES2236902T3 (pt)
FR (1)	FR2762843B1 (pt)
MA (1)	MA26488A1 (pt)
PT (1)	PT979244E (pt)
TN (1)	TNSN98057A1 (pt)
WO (1)	WO1998049193A1 (pt)
ZA (1)	ZA983618B (pt)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US20030220234A1 (en)	1998-11-02	2003-11-27	Selvaraj Naicker	Deuterated cyclosporine analogs and their use as immunodulating agents
EP2116228A1 (en) *	2001-10-19	2009-11-11	Isotechnika Inc.	Novel cyclosporin analog microemulsion preconcentrates
WO2003033526A2 (en)	2001-10-19	2003-04-24	Isotechnika Inc.	Synthesis of cyclosporin analogs
KR20040039622A (ko) *	2002-11-04	2004-05-12	주식회사 엘지생활건강	모발 성장 효과를 갖는 사이클로스포린 3 위치 유도체를유효성분으로 하는 모발 성장 촉진제
US20060130158A1 (en) *	2002-08-30	2006-06-15	Turner Andrew J	Modified transferrin fusion proteins comprising duplicate transferrin amino or carboxy terminal domains
JP2006524232A (ja)	2003-03-17	2006-10-26	アルバニーモレキュラーリサーチインコーポレーティッド	新規サイクロスポリン
ATE488252T1 (de) *	2003-05-05	2010-12-15	Virxsys Corp	Erhöhte transduktion mit abc- transportersubstratenhemmern
JP2008514701A (ja)	2004-09-29	2008-05-08	エーエムアールテクノロジーインコーポレイテッド	シクロスポリンアルキン類似体およびそれらの薬学的使用
EP1804823A4 (en)	2004-09-29	2010-06-09	Amr Technology Inc	NEW CYCLOSPORIN ANALOGUE AND ITS PHARMACEUTICAL APPLICATIONS
JP5139065B2 (ja) *	2004-10-01	2013-02-06	スシネキスインク	Ｃ型肝炎感染の治療及び予防のための３−エーテル及び３−チオエーテル置換シクロスポリン誘導体
US7196161B2 (en) *	2004-10-01	2007-03-27	Scynexis Inc.	3-ether and 3-thioether substituted cyclosporin derivatives for the treatment and prevention of hepatitis C infection
US7361636B2 (en)	2004-10-06	2008-04-22	Amr Technology, Inc.	Cyclosporin alkynes and their utility as pharmaceutical agents
US8329658B2 (en) *	2005-09-30	2012-12-11	Scynexis, Inc.	Arylalkyl and heteroarylalkyl derivatives of cyclosporine A for the treatment and prevention of viral infection
BRPI0616476A2 (pt) *	2005-09-30	2011-06-21	Scynexis Inc	uso de uma quantidade terapeuticamente eficaz de um derivado de ciclosporina, e, composição farmacêutica
US9839667B2 (en)	2005-10-14	2017-12-12	Allergan, Inc.	Prevention and treatment of ocular side effects with a cyclosporin
EP3103468B1 (en) *	2005-10-14	2020-07-15	Allergan, Inc.	Prevention of drug-associated keratoconjunctivitis with a cyclosporin
US7745400B2 (en) *	2005-10-14	2010-06-29	Gregg Feinerman	Prevention and treatment of ocular side effects with a cyclosporin
ATE502633T1 (de)	2006-05-19	2011-04-15	Scynexis Inc	Cyclosporins zur behandlung und vorbeugung von augenerkrankungen
EP2027761A1 (fr) *	2006-06-02	2009-02-25	Claude Annie Perrichon	Gestion des electrons actifs
US7576057B2 (en)	2006-11-20	2009-08-18	Scynexis, Inc.	Cyclic peptides
US20080255038A1 (en) *	2007-04-11	2008-10-16	Samuel Earl Hopkins	Pharmaceutical compositions
US20090306033A1 (en) *	2008-06-06	2009-12-10	Keqiang Li	Novel cyclic peptides
US9090671B2 (en)	2008-06-06	2015-07-28	Scynexis, Inc.	Macrocyclic peptides
BRPI0911709A2 (pt) *	2008-07-30	2017-06-20	Isotechnika Labs Inc	composto, processo para a produção de um composto, composição farmacêutica e método de tratar uma doença mediada a ciclofilina em um mamífero
DE102008060549A1 (de)	2008-12-04	2010-06-10	MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V.	Wirkstoff-Peptid-Konstrukt zur extrazellulären Anreicherung
EP2376524B1 (en) *	2008-12-31	2017-03-15	Cypralis Limited	Derivatives of cyclosporin a
SG173180A1 (en)	2009-01-30	2011-09-29	Enanta Pharm Inc	Cyclosporin analogues for preventing or treating hepatitis c infection
US8481483B2 (en) *	2009-02-19	2013-07-09	Enanta Pharmaceuticals, Inc.	Cyclosporin analogues
WO2010138422A1 (en) *	2009-05-27	2010-12-02	Allergan, Inc.	Cyclosporin derivatives for enhancing the growth of hair
AU2010254316A1 (en) *	2009-05-27	2011-12-22	Allergan, Inc.	Cyclosporin derivatives for treating inflammatory diseases and conditions
US8685917B2 (en) *	2009-07-09	2014-04-01	Enanta Pharmaceuticals, Inc.	Cyclosporin analogues
AU2010339460A1 (en)	2009-12-30	2012-07-19	Scynexis Inc.	Cyclosporine analogues
US9175042B2 (en) *	2010-10-12	2015-11-03	Allergan, Inc.	Cyclosporin analogs
RU2013119869A (ru)	2010-10-12	2014-11-20	Аллерган, Инк.	Аналоги циклоспорина
JP6144627B2 (ja)	2010-12-15	2017-06-07	コントラヴィアファーマシューティカルズ、インク．	アミノ酸１および３で修飾されたシクロスポリン類似体分子
DE102011111991A1 (de) *	2011-08-30	2013-02-28	Lead Discovery Center Gmbh	Neue Cyclosporin-Derivate
EP2705856A1 (en)	2012-09-07	2014-03-12	Deutsches Zentrum für Neurodegenerative Erkrankungen e.V.	Compounds for the treatment of neurodegenerative disorders
WO2014049540A2 (en)	2012-09-29	2014-04-03	Novartis Ag	Cyclic peptides and use as medicines

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0194972B1 (en) *	1985-03-11	1992-07-29	Sandoz Ag	Novel cyclosporins
US4814323A (en) *	1986-03-25	1989-03-21	Andrieu J M	Process for the treatment and the prevention of AIDS and other disorders induced by the LAV/HTLV III virus
US4798823A (en) *	1987-06-03	1989-01-17	Merck & Co., Inc.	New cyclosporin analogs with modified "C-9 amino acids"
US4885276A (en) *	1987-06-03	1989-12-05	Merck & Co., Inc.	Cyclosporin analogs with modified "C-9 amino acids"
ATE148469T1 (de) *	1990-11-02	1997-02-15	Sandoz Ag	Zyklosporine
US5512555A (en) *	1994-07-21	1996-04-30	Merck & Co., Inc.	Method of treating sweat-related conditions using finasteride, epristeride and a cholestan-3-one
PL324531A1 (en) *	1995-07-17	1998-06-08	Chem Ag C	Derivatives of cyclosporin effective against hiv virus

1997
- 1997-04-30 FR FR9705351A patent/FR2762843B1/fr not_active Expired - Fee Related
1998
- 1998-04-27 MA MA25048A patent/MA26488A1/fr unknown
- 1998-04-27 EP EP98922872A patent/EP0979244B1/fr not_active Expired - Lifetime
- 1998-04-27 ES ES98922872T patent/ES2236902T3/es not_active Expired - Lifetime
- 1998-04-27 AT AT98922872T patent/ATE290015T1/de active
- 1998-04-27 PT PT98922872T patent/PT979244E/pt unknown
- 1998-04-27 AU AU75357/98A patent/AU7535798A/en not_active Abandoned
- 1998-04-27 WO PCT/FR1998/000838 patent/WO1998049193A1/fr not_active Ceased
- 1998-04-27 DE DE69829175T patent/DE69829175T2/de not_active Expired - Lifetime
- 1998-04-27 JP JP54666498A patent/JP2001524105A/ja active Pending
- 1998-04-29 ZA ZA983618A patent/ZA983618B/xx unknown
- 1998-04-29 TN TNTNSN98057A patent/TNSN98057A1/fr unknown
- 1998-04-30 US US09/069,959 patent/US5977067A/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
EP0979244A1 (fr)	2000-02-16
DE69829175T2 (de)	2006-02-16
ES2236902T3 (es)	2005-07-16
WO1998049193A1 (fr)	1998-11-05
MA26488A1 (fr)	2004-12-20
ATE290015T1 (de)	2005-03-15
FR2762843A1 (fr)	1998-11-06
DE69829175D1 (de)	2005-04-07
TNSN98057A1 (fr)	2005-03-15
AU7535798A (en)	1998-11-24
ZA983618B (en)	1998-11-04
US5977067A (en)	1999-11-02
FR2762843B1 (fr)	1999-12-10
EP0979244B1 (fr)	2005-03-02
JP2001524105A (ja)	2001-11-27

Publication	Publication Date	Title
ZA983618B (en)	1998-11-04	Novel cyclosporin derivatives their preparation and the pharmaceutical compositions which contain them
PT948527E (pt)	2002-11-29	Novos derivados de ciclosporina sua preparacao e composicoes farmaceuticas que os contem
PT951474E (pt)	2002-11-29	Novos derivados da ciclosporina sua preparacao e composicoes farmaceuticas que os contem
TR200200579T2 (tr)	2002-12-23	Amino-tirazolpiridin türevleri.
BG103945A (bg)	2000-07-31	Производни на 4"-заместен-9-деоксо-9а-аза-9а- хомоеритромицин а
BR0215240A (pt)	2004-10-26	Derivados de calcona e seu uso no tratamento de doenças
BR0008059A (pt)	2002-03-26	Composições de valdecoxib
SE9504661D0 (sv)	1995-12-22	New compounds
PT951473E (pt)	2002-11-29	Novos derivados da ciclosporina sua preparacao e composicoes farmaceuticas que os contem
KR0141913B1 (en)	1998-06-01	Anti-virus agents
FI972434A0 (fi)	1997-06-06	Lamotrigiiniä sisältävä farmaseuttinen koostumus
ATE108437T1 (de)	1994-07-15	Substituierte diaminophthalimide und analoga.
BR0113590A (pt)	2003-07-22	7-oxo-piridopirimidinas
MD1560F2 (en)	2000-11-30	Cyclic compounds, pharmaceutical compositions on base thereof and methods of treatment of infections or diseases provoked by retroviruses.
DK0387821T3 (da)	1994-09-19	2-Alkyl-4-arylmethylchinoliner, deres anvendelse og lægemidler fremstillet hermed
GR3019274T3 (en)	1996-06-30	Substituted 3-piperazinylalkyl-2,3-dihydro-4H-1,3-benzoxazine-4-ones, their preparation and their therapeutical use
PH27446A (en)	1993-07-02	Compound with gastric acid inhibitory effect
FI973184A7 (fi)	1997-09-30	Kombinaatioterapia HIV-infektiota varten käyttäen HIV-proteaasi-inhibi ittoria indinavir ja käänteistranskriptaasi-inhibiittoria 3TC, mahdoll isesti yhdessä AZT:n, DDI:n tai DDC:n kanssa
SE9504662D0 (sv)	1995-12-22	New compounds
BR0011845A (pt)	2002-03-05	Complexo farmacêutico
EP1411956B8 (en)	2005-10-05	Use of oversulfated polysaccharides as inhibitors of hiv
PT989994E (pt)	2005-08-31	Derivados de estreptograminas, a sua preparacao e as composicoes que os contem
DE69430074D1 (de)	2002-04-11	Analgetische 4-arylisoindolen
BR0213463A (pt)	2004-11-09	Composições farmacêuticas contendo macrólidos
EP1451184A4 (en)	2005-02-02	DIMERE COMPOUNDS AND THEIR USE AS ANTIVIRAL AGENTS