BR0312876A - Método de preparação de formas de dosagem sólidas revestidas em duas camadas compreendendo um polìmero insolúvel em água e um agente formador de poros solúvel em água - Google Patents
Método de preparação de formas de dosagem sólidas revestidas em duas camadas compreendendo um polìmero insolúvel em água e um agente formador de poros solúvel em águaInfo
- Publication number
- BR0312876A BR0312876A BR0312876-8A BR0312876A BR0312876A BR 0312876 A BR0312876 A BR 0312876A BR 0312876 A BR0312876 A BR 0312876A BR 0312876 A BR0312876 A BR 0312876A
- Authority
- BR
- Brazil
- Prior art keywords
- water
- dosage forms
- soluble pore
- forming agent
- coated
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 4
- 239000003795 chemical substances by application Substances 0.000 title abstract 2
- 239000002552 dosage form Substances 0.000 title abstract 2
- 239000007787 solid Substances 0.000 title abstract 2
- 229920003176 water-insoluble polymer Polymers 0.000 title abstract 2
- 239000007909 solid dosage form Substances 0.000 abstract 4
- 239000011248 coating agent Substances 0.000 abstract 2
- 238000000576 coating method Methods 0.000 abstract 2
- 238000001035 drying Methods 0.000 abstract 2
- 239000013543 active substance Substances 0.000 abstract 1
- 229920001688 coating polymer Polymers 0.000 abstract 1
- 238000013265 extended release Methods 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 239000011148 porous material Substances 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
- A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurology (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Neurosurgery (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Psychology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Glanulating (AREA)
Abstract
"MéTODO DE PREPARAçãO DE FORMAS DE DOSAGEM SóLIDAS REVESTIDAS EM DUAS CAMADAS COMPREENDENDO UM POLìMERO INSOLúVEL EM áGUA E UM AGENTE FORMADOR DE POROS SOLúVEL EM áGUA". Esta invenção apresenta um método para preparar uma forma de dosagem sólida revestida, em que uma forma de dosagem sólida, tal como um comprimido prensado com um agente ativo disperso no seu interior, é revestido pelo menos duas vezes com uma solução de revestimento, compreendendo um polímero de revestimento insolúvel em água e um agente formador de poros solúvel em água, sendo seco depois de, pelo menos, o primeiro passo de revestimento. O método da presente invenção permite a produção de formas de dosagem sólidas, revestidas e secagem das, utilizando tempos de secagem muito reduzidos. As formas de dosagem sólidas revestidas, produzidas de acordo com a presente invenção, revelaram ter características de liberação extensa e prolongada.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US39837002P | 2002-07-25 | 2002-07-25 | |
| PCT/US2003/022985 WO2004010982A1 (en) | 2002-07-25 | 2003-07-24 | Method of preparing solid dosage forms coated in two layers comprising a water-insoluble polymer and a water-soluble pore former |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR0312876A true BR0312876A (pt) | 2005-06-28 |
Family
ID=31188387
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR0312876-8A BR0312876A (pt) | 2002-07-25 | 2003-07-24 | Método de preparação de formas de dosagem sólidas revestidas em duas camadas compreendendo um polìmero insolúvel em água e um agente formador de poros solúvel em água |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20040137156A1 (pt) |
| EP (1) | EP1526843A1 (pt) |
| JP (1) | JP2005538105A (pt) |
| AR (1) | AR040684A1 (pt) |
| AU (1) | AU2003261223A1 (pt) |
| BR (1) | BR0312876A (pt) |
| CA (1) | CA2488860A1 (pt) |
| MX (1) | MXPA05001003A (pt) |
| TW (1) | TW200413033A (pt) |
| WO (1) | WO2004010982A1 (pt) |
Families Citing this family (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8071128B2 (en) | 1996-06-14 | 2011-12-06 | Kyowa Hakko Kirin Co., Ltd. | Intrabuccally rapidly disintegrating tablet and a production method of the tablets |
| US9358214B2 (en) | 2001-10-04 | 2016-06-07 | Adare Pharmaceuticals, Inc. | Timed, sustained release systems for propranolol |
| US20050226926A1 (en) | 2002-07-25 | 2005-10-13 | Pfizer Inc | Sustained-release tablet composition of pramipexole |
| PA8578501A1 (es) | 2002-07-25 | 2005-02-04 | Pharmacia Corp | Forma de dosificacion una vez al dia de pramipexol |
| CA2509620A1 (en) * | 2002-12-17 | 2004-07-01 | Wakunaga Pharmaceutical Co., Ltd. | Light-shielding agent and film-forming composition |
| US8367111B2 (en) * | 2002-12-31 | 2013-02-05 | Aptalis Pharmatech, Inc. | Extended release dosage forms of propranolol hydrochloride |
| UA93608C2 (ru) | 2004-08-13 | 2011-02-25 | Берингер Ингельхайм Интернациональ Гмбх | композициЯ таблетки пролонгированного высвобождения, которая содержит прамипексол или его фармацевтически приемлемую соль, СПОСОБ EE ИЗГОТОВЛЕНИЯ И EE ПРИМЕНЕНИЕ |
| AU2011244902B2 (en) * | 2004-08-13 | 2012-09-27 | Boehringer Ingelheim International Gmbh | Extended release pellet formulation containing pramipexole or a pharmaceutically acceptable salt thereof, method for manufacturing the same and use thereof |
| CN101022788B (zh) * | 2004-08-13 | 2010-11-10 | 贝林格尔·英格海姆国际有限公司 | 包含普拉克索或其可药用盐的延长释放小球制剂、其制备方法及其用途 |
| US8747895B2 (en) | 2004-09-13 | 2014-06-10 | Aptalis Pharmatech, Inc. | Orally disintegrating tablets of atomoxetine |
| US9884014B2 (en) | 2004-10-12 | 2018-02-06 | Adare Pharmaceuticals, Inc. | Taste-masked pharmaceutical compositions |
| NZ589750A (en) * | 2004-10-21 | 2012-07-27 | Aptalis Pharmatech Inc | Taste-masked pharmaceutical compositions with gastrosoluble pore-formers |
| WO2006046256A1 (en) * | 2004-10-27 | 2006-05-04 | Alembic Limited | Extended release formulation of pramipexole dihydrochloride |
| US20060105038A1 (en) * | 2004-11-12 | 2006-05-18 | Eurand Pharmaceuticals Limited | Taste-masked pharmaceutical compositions prepared by coacervation |
| US9161918B2 (en) | 2005-05-02 | 2015-10-20 | Adare Pharmaceuticals, Inc. | Timed, pulsatile release systems |
| US20060275364A1 (en) * | 2005-05-26 | 2006-12-07 | Ahmed Salah U | Flexible Solid Dosage Forms and Methods of Making and Using the Same |
| WO2007002518A1 (en) * | 2005-06-23 | 2007-01-04 | Spherics, Inc. | Delayed release or extended-delayed release dosage forms of pramipexole |
| WO2007090883A1 (en) * | 2006-02-10 | 2007-08-16 | Boehringer Ingelheim International Gmbh | Extended release formulation |
| WO2007090882A2 (en) * | 2006-02-10 | 2007-08-16 | Boehringer Ingelheim International Gmbh | Pharmaceutical extended release compositions comprising pramipexole |
| SA07280459B1 (ar) | 2006-08-25 | 2011-07-20 | بيورديو فارما إل. بي. | أشكال جرعة صيدلانية للتناول عن طريق الفم مقاومة للعبث تشتمل على مسكن شبه أفيوني |
| DK2152250T3 (da) * | 2007-05-07 | 2019-12-09 | Evonik Degussa Gmbh | Faste doseringsformer, der omfatter et enterisk overtræk, med accelereret lægemiddelfrigivelse |
| EP2175843B1 (en) | 2007-08-08 | 2014-10-08 | Inventia Healthcare Private Limited | Extended release compositions comprising tolterodine |
| US20090194533A1 (en) * | 2008-02-04 | 2009-08-06 | Lizerbram Eric K | Closure with additive reservoir |
| CN102958515A (zh) | 2009-12-02 | 2013-03-06 | 阿普塔利斯制药有限公司 | 非索非那定微胶囊及含有非索非那定微胶囊的组合物 |
| US20110212171A1 (en) * | 2010-01-08 | 2011-09-01 | Eurand, Inc. | Taste masked topiramate composition and an orally disintegrating tablet comprising the same |
| KR101307334B1 (ko) * | 2010-07-02 | 2013-09-12 | 주식회사 바이오파마티스 | 프라미펙솔 또는 이의 약학적으로 허용되는 염을 포함하는 안정성이 개선된 서방형 약학 조성물 |
| CN102018658B (zh) * | 2010-07-16 | 2014-03-12 | 钟术光 | 一种控释制剂及其制备方法 |
| WO2013034173A1 (en) | 2011-09-06 | 2013-03-14 | Synthon Bv | Pramipexole extended release tablets |
| US8993041B2 (en) * | 2012-10-15 | 2015-03-31 | New Jersey Institute Of Technology | Taste masked active pharmaceutical powder compositions and processes for making them |
| CN104606162B (zh) * | 2015-01-07 | 2017-03-29 | 海南康虹医药科技开发有限公司 | 一种盐酸普拉克索缓释制剂及其制备方法 |
| JP6366547B2 (ja) * | 2015-08-03 | 2018-08-01 | 大原薬品工業株式会社 | 光安定性が向上した、プラミペキソール製剤包装体 |
| CN109939658B (zh) * | 2019-04-17 | 2022-11-01 | 邱俊琅 | 一种萃取涂层、固相微萃取探针及其制备方法和应用 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US612933A (en) * | 1898-10-25 | J s rogees | ||
| US4600645A (en) * | 1985-01-31 | 1986-07-15 | Warner-Lambert Company | Process for treating dosage forms |
| GB8707416D0 (en) * | 1987-03-27 | 1987-04-29 | Wellcome Found | Pharmaceutical formulations |
| US5126146A (en) * | 1989-10-23 | 1992-06-30 | Merck & Co., Inc. | Cellulosic coating |
| US5472712A (en) * | 1991-12-24 | 1995-12-05 | Euroceltique, S.A. | Controlled-release formulations coated with aqueous dispersions of ethylcellulose |
| US5681585A (en) * | 1991-12-24 | 1997-10-28 | Euro-Celtique, S.A. | Stabilized controlled release substrate having a coating derived from an aqueous dispersion of hydrophobic polymer |
| US5958459A (en) * | 1991-12-24 | 1999-09-28 | Purdue Pharma L.P. | Opioid formulations having extended controlled released |
| IL110014A (en) * | 1993-07-01 | 1999-11-30 | Euro Celtique Sa | Solid controlled-release oral dosage forms of opioid analgesics |
| US5945124A (en) * | 1995-07-05 | 1999-08-31 | Byk Gulden Chemische Fabrik Gmbh | Oral pharmaceutical composition with delayed release of active ingredient for pantoprazole |
| US6432322B1 (en) * | 2000-02-02 | 2002-08-13 | Engelhard Corporation | Massive bodies for producing highly converted solutions of chlorine dioxde |
| WO2003053420A1 (en) * | 2001-12-20 | 2003-07-03 | Pharmacia Corporation | Multiple-pulse extended release formulations of clindamycin |
-
2003
- 2003-07-24 BR BR0312876-8A patent/BR0312876A/pt not_active IP Right Cessation
- 2003-07-24 CA CA002488860A patent/CA2488860A1/en not_active Abandoned
- 2003-07-24 US US10/626,374 patent/US20040137156A1/en not_active Abandoned
- 2003-07-24 AU AU2003261223A patent/AU2003261223A1/en not_active Abandoned
- 2003-07-24 MX MXPA05001003A patent/MXPA05001003A/es not_active Application Discontinuation
- 2003-07-24 WO PCT/US2003/022985 patent/WO2004010982A1/en not_active Ceased
- 2003-07-24 JP JP2004524711A patent/JP2005538105A/ja not_active Withdrawn
- 2003-07-24 AR AR20030102669A patent/AR040684A1/es not_active Application Discontinuation
- 2003-07-24 EP EP03771732A patent/EP1526843A1/en not_active Withdrawn
- 2003-07-25 TW TW092120408A patent/TW200413033A/zh unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP1526843A1 (en) | 2005-05-04 |
| WO2004010982A1 (en) | 2004-02-05 |
| JP2005538105A (ja) | 2005-12-15 |
| AR040684A1 (es) | 2005-04-13 |
| AU2003261223A1 (en) | 2004-02-16 |
| CA2488860A1 (en) | 2004-02-05 |
| TW200413033A (en) | 2004-08-01 |
| MXPA05001003A (es) | 2005-05-16 |
| US20040137156A1 (en) | 2004-07-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B08F | Application fees: application dismissed [chapter 8.6 patent gazette] |
Free format text: REFERENTE 4A., 5A., 6A., E 7A. ANUIDADES. |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2064 DE 27/07/2010. |