ES2101082T3 - Composiciones de liberacion controlada. - Google Patents

Composiciones de liberacion controlada.

Info

Publication number
ES2101082T3
ES2101082T3 ES92902527T ES92902527T ES2101082T3 ES 2101082 T3 ES2101082 T3 ES 2101082T3 ES 92902527 T ES92902527 T ES 92902527T ES 92902527 T ES92902527 T ES 92902527T ES 2101082 T3 ES2101082 T3 ES 2101082T3
Authority
ES
Spain
Prior art keywords
controlled release
release compositions
core
vinylpyrolidine
caolin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES92902527T
Other languages
English (en)
Inventor
John Michael Newton
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BTG International Ltd
Original Assignee
British Technology Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by British Technology Group Ltd filed Critical British Technology Group Ltd
Application granted granted Critical
Publication of ES2101082T3 publication Critical patent/ES2101082T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/2853—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers, poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Lubricants (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Glass Compositions (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

UNA COMPOSICION DE LIBERACION CONTROLADA QUE COMPRENDE UN NUCLEO EXTRUIDO DE MATERIAL ACTIVO Y EXCIPIENTES, EN DONDE DICHO NUCLEO ESTA REVESTIDO POR UN REVESTIMIENTO INSOLUBLE EN AGUA. PREFERENTEMENTE EL NUCLEO CONTIENE UN AGENTE ACTIVO FARMACEUTICAMENTE ADECUADO JUNTO CON CELULOSA MICROCRISTALINA, UNA ARCILLA TAL COMO CAOLIN Y UN AGLUTINANTE TAL COMO POLI(VINILPIRROLIDINA).
ES92902527T 1990-11-22 1991-11-21 Composiciones de liberacion controlada. Expired - Lifetime ES2101082T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB909025372A GB9025372D0 (en) 1990-11-22 1990-11-22 Pharmaceutical dosage forms

Publications (1)

Publication Number Publication Date
ES2101082T3 true ES2101082T3 (es) 1997-07-01

Family

ID=10685781

Family Applications (1)

Application Number Title Priority Date Filing Date
ES92902527T Expired - Lifetime ES2101082T3 (es) 1990-11-22 1991-11-21 Composiciones de liberacion controlada.

Country Status (14)

Country Link
EP (1) EP0559813B1 (es)
JP (1) JPH06502636A (es)
KR (1) KR930701984A (es)
AT (1) ATE151283T1 (es)
AU (1) AU653372B2 (es)
CA (1) CA2096733A1 (es)
DE (1) DE69125619T2 (es)
ES (1) ES2101082T3 (es)
FI (1) FI932320A7 (es)
GB (2) GB9025372D0 (es)
HU (1) HUT65756A (es)
NO (1) NO931859L (es)
WO (1) WO1992009270A1 (es)
ZA (1) ZA919185B (es)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY110880A (en) * 1991-01-30 1999-06-30 The Wellcome Foundation Ltd Water-dispersible tablets
US5629016A (en) * 1991-01-30 1997-05-13 Glaxo Wellcome Inc. Water-dispersible tablets
GB9215908D0 (en) * 1992-07-27 1992-09-09 Wellcome Found Water dispersible tablets
TW246635B (es) * 1992-10-08 1995-05-01 Shell Internat Res Schappej B V
DK66493D0 (da) * 1993-06-08 1993-06-08 Ferring A S Praeparater, isaer til brug ved behandling af inflammatoriske tarmsygdomme eller til at opnaa forbedret saarheling
US5698226A (en) * 1993-07-13 1997-12-16 Glaxo Wellcome Inc. Water-dispersible tablets
US6028190A (en) 1994-02-01 2000-02-22 The Regents Of The University Of California Probes labeled with energy transfer coupled dyes
US6166024A (en) 1995-03-30 2000-12-26 Mayo Foundation For Medical Education And Research Use of topical azathioprine and thioguanine to treat colorectal adenomas
HRP970485A2 (en) 1996-09-13 1998-08-31 Joerg Rosenberg Process for producing solid pharmaceutical forms
DE19649100A1 (de) * 1996-11-27 1998-06-04 Lohmann Therapie Syst Lts Verfahren zur verlustarmen Herstellung wirkstoffhaltiger scheibenförmiger Formkörper und diese enthaltende transdermale therapeutische Systeme
JP4533531B2 (ja) 1998-04-03 2010-09-01 ビーエム リサーチ エイ／エス 制御放出組成物
DE19840256A1 (de) * 1998-09-03 2000-03-09 Basf Ag Verfahren zur Herstellung von beschichteten festen Dosierungsformen
DE59905248D1 (de) 1999-01-29 2003-05-28 Disphar Int Bv Pharmazeutische zusammensetzungen
AU2001289653A1 (en) * 2000-07-14 2002-01-30 Universiteit Gent Composite solid shaped articles for the controlled delivery of biologically active ingredients
EP1429744A1 (en) 2001-09-21 2004-06-23 Egalet A/S Morphine polymer release system
US20040234602A1 (en) 2001-09-21 2004-11-25 Gina Fischer Polymer release system
US20030203027A1 (en) * 2002-04-26 2003-10-30 Ethicon, Inc. Coating technique for deposition of drug substance on a substrate
BR0309844A (pt) * 2002-05-07 2005-02-15 Control Delivery Sys Inc Processos para formação de um dispositivo para a distribuição de droga
GB0214013D0 (en) 2002-06-18 2002-07-31 Euro Celtique Sa Pharmaceutical product
EP1562552A1 (en) 2002-11-08 2005-08-17 Egalet A/S Controlled release carvedilol compositions
ATE454886T1 (de) 2003-03-26 2010-01-15 Egalet As Matrixzubereitungen für die kontrollierte darreichung von arzneistoffen
WO2004084868A1 (en) 2003-03-26 2004-10-07 Egalet A/S Morphine controlled release system
DE102004042139B4 (de) * 2004-08-31 2009-06-10 Aristocon Verwaltungs- Gmbh Perorale Darreichungsformen zur Erzielung eines Retardierungseffektes nach der Arzneimitteleinnahme mit einer Mahlzeit
EP2155167A2 (en) 2007-06-04 2010-02-24 Egalet A/S Controlled release pharmaceutical compositions for prolonged effect
NZ594207A (en) 2009-02-06 2013-03-28 Egalet Ltd Immediate release composition resistant to abuse by intake of alcohol
NZ597283A (en) 2009-06-24 2013-07-26 Egalet Ltd Controlled release formulations
WO2011107944A2 (en) * 2010-03-04 2011-09-09 Wockhardt Limited Modified release dosage form
BR112015000150A2 (pt) 2012-07-06 2017-06-27 Egalet Ltd composições farmacêuticas dissuasoras de abuso de liberação controlada
JP7407595B2 (ja) * 2016-10-05 2024-01-04 タイタン ファーマシューティカルズ インコーポレイテッド バースト放出を低減する薬剤送達用の埋込可能な装置

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK62184D0 (da) * 1984-02-10 1984-02-10 Benzon As Alfred Diffusionsovertrukket polydepotpraeparat
GB2170104A (en) * 1985-01-30 1986-07-30 Warner Lambert Co Coated pharmaceutical dosage forms
IE861284L (en) * 1986-05-14 1987-11-14 Birex Res And Dev Ltd And Carm Controlled release ketoprofen.
US4810501A (en) * 1986-06-17 1989-03-07 Warner-Lambert Company Sustained release pharmaceutical preparations
GB8618811D0 (en) * 1986-08-01 1986-09-10 Approved Prescription Services Sustained release ibuprofen formulation
US5158881A (en) * 1987-11-17 1992-10-27 Brown University Research Foundation Method and system for encapsulating cells in a tubular extrudate in separate cell compartments

Also Published As

Publication number Publication date
DE69125619T2 (de) 1997-09-11
NO931859D0 (no) 1993-05-21
KR930701984A (ko) 1993-09-08
WO1992009270A1 (en) 1992-06-11
ZA919185B (en) 1992-09-30
EP0559813B1 (en) 1997-04-09
FI932320L (fi) 1993-07-09
CA2096733A1 (en) 1992-05-23
HU9301499D0 (en) 1993-09-28
HUT65756A (en) 1994-07-28
DE69125619D1 (de) 1997-05-15
AU8909691A (en) 1992-06-25
ATE151283T1 (de) 1997-04-15
GB9124776D0 (en) 1992-01-15
JPH06502636A (ja) 1994-03-24
FI932320A7 (fi) 1993-07-09
GB2249957A (en) 1992-05-27
GB9025372D0 (en) 1991-01-09
AU653372B2 (en) 1994-09-29
NO931859L (no) 1993-07-21
FI932320A0 (fi) 1993-05-21
GB2249957B (en) 1994-11-23
EP0559813A1 (en) 1993-09-15

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