AR032037A1 - Particulas de textura enmascarada que contienen un ingrediente activo - Google Patents

Particulas de textura enmascarada que contienen un ingrediente activo

Info

Publication number
AR032037A1
AR032037A1 ARP010106010A ARP010106010A AR032037A1 AR 032037 A1 AR032037 A1 AR 032037A1 AR P010106010 A ARP010106010 A AR P010106010A AR P010106010 A ARP010106010 A AR P010106010A AR 032037 A1 AR032037 A1 AR 032037A1
Authority
AR
Argentina
Prior art keywords
particles
active ingredient
coating layer
core
masked
Prior art date
Application number
ARP010106010A
Other languages
English (en)
Original Assignee
Mcneil Ppc Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mcneil Ppc Inc filed Critical Mcneil Ppc Inc
Publication of AR032037A1 publication Critical patent/AR032037A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A61K9/2081—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Zoology (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Organic Chemistry (AREA)
  • Rheumatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Se describen partículas de textura enmascarada y tabletas masticables elaboradas a partir de las mismas; las partículas de textura enmascarada constan de un nucleo que contiene un ingrediente activo, una primera capa de revestimiento opcional que consta de un agente de enmascaramiento de sabor que cubre sustancialmente el nucleo; y una segunda capa de revestimiento, que como opcion puede cubrir sustancialmente la primera capa de revestimiento o el nucleo, que consta de un polímero formador de película y un agente antigranuloso; las partículas pueden producirse en forma de tableta, tal como una forma de tableta masticable, que provee la liberacion inmediata del ingrediente activo.
ARP010106010A 2000-12-21 2001-12-21 Particulas de textura enmascarada que contienen un ingrediente activo AR032037A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US09/745,243 US20020119196A1 (en) 2000-12-21 2000-12-21 Texture masked particles containing an active ingredient

Publications (1)

Publication Number Publication Date
AR032037A1 true AR032037A1 (es) 2003-10-22

Family

ID=24995856

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP010106010A AR032037A1 (es) 2000-12-21 2001-12-21 Particulas de textura enmascarada que contienen un ingrediente activo

Country Status (17)

Country Link
US (2) US20020119196A1 (es)
EP (1) EP1219291B1 (es)
JP (1) JP2002272817A (es)
KR (1) KR20020050754A (es)
CN (1) CN100544705C (es)
AR (1) AR032037A1 (es)
AT (1) ATE405250T1 (es)
AU (1) AU783593B2 (es)
BR (1) BR0106912A (es)
CA (1) CA2365844C (es)
CO (1) CO5390070A1 (es)
DE (1) DE60135435D1 (es)
ES (1) ES2311007T3 (es)
HK (2) HK1045817B (es)
MX (1) MXPA02000277A (es)
NZ (1) NZ516341A (es)
ZA (1) ZA200110547B (es)

Families Citing this family (56)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8900498B2 (en) 2001-10-12 2014-12-02 Monosol Rx, Llc Process for manufacturing a resulting multi-layer pharmaceutical film
US10285910B2 (en) 2001-10-12 2019-05-14 Aquestive Therapeutics, Inc. Sublingual and buccal film compositions
US8900497B2 (en) 2001-10-12 2014-12-02 Monosol Rx, Llc Process for making a film having a substantially uniform distribution of components
US11207805B2 (en) 2001-10-12 2021-12-28 Aquestive Therapeutics, Inc. Process for manufacturing a resulting pharmaceutical film
US8765167B2 (en) 2001-10-12 2014-07-01 Monosol Rx, Llc Uniform films for rapid-dissolve dosage form incorporating anti-tacking compositions
US20070281003A1 (en) 2001-10-12 2007-12-06 Fuisz Richard C Polymer-Based Films and Drug Delivery Systems Made Therefrom
US7357891B2 (en) 2001-10-12 2008-04-15 Monosol Rx, Llc Process for making an ingestible film
US8603514B2 (en) 2002-04-11 2013-12-10 Monosol Rx, Llc Uniform films for rapid dissolve dosage form incorporating taste-masking compositions
US20110033542A1 (en) 2009-08-07 2011-02-10 Monosol Rx, Llc Sublingual and buccal film compositions
US20190328679A1 (en) 2001-10-12 2019-10-31 Aquestive Therapeutics, Inc. Uniform films for rapid-dissolve dosage form incorporating anti-tacking compositions
US6723348B2 (en) * 2001-11-16 2004-04-20 Ethypharm Orodispersible tablets containing fexofenadine
GB2384986B (en) * 2002-02-12 2004-01-07 Reckitt Benckiser Healthcare Compositions for the treatment of disorders of the upper gastrointestinal tract
US20030190343A1 (en) * 2002-03-05 2003-10-09 Pfizer Inc. Palatable pharmaceutical compositions for companion animals
AU2003209475A1 (en) * 2002-03-07 2003-09-16 Vectura Limited Fast melt multiparticulate formulations for oral delivery
US20040001885A1 (en) * 2002-06-27 2004-01-01 Unchalee Kositprapa Rapidly disintegrating antihistamine formulation
US7384970B2 (en) * 2003-03-24 2008-06-10 Irm Llc Inhibitors of cathepsin S
US20050042289A1 (en) * 2003-04-29 2005-02-24 Yamanouchi Pharma Technologies, Inc. Tablets and methods for modified release of hydrophylic and other active agents
US7282217B1 (en) 2003-08-29 2007-10-16 Kv Pharmaceutical Company Rapidly disintegrable tablets
US20050053655A1 (en) * 2003-09-05 2005-03-10 Pharmaceutical Industry Technology And Development Center Rapid disintegrating tablets (RDTs) for pharmaceutical use and method for preparing the same
EP1679066A4 (en) * 2003-10-27 2011-06-22 Astellas Pharma Inc MEDICINAL COATING MICROPARTICLES FOR A MOUTH-DISABLE TABLET
US20050175689A1 (en) * 2003-10-27 2005-08-11 Yamanouchi Pharmaceutical Co., Ltd. Coated fine particles containing drug for intrabuccally fast disintegrating tablet
US7201920B2 (en) 2003-11-26 2007-04-10 Acura Pharmaceuticals, Inc. Methods and compositions for deterring abuse of opioid containing dosage forms
US7879354B2 (en) * 2004-01-13 2011-02-01 Mcneil-Ppc, Inc. Rapidly disintegrating gelatinous coated tablets
MXPA06010908A (es) * 2004-03-25 2006-12-15 Astellas Pharma Inc Composicion para la preparacion farmaceutica solida de solifenacina o una sal de la misma.
AU2005320672B2 (en) * 2004-12-27 2011-01-06 Astellas Pharma Inc. Stable particulate pharmaceutical composition of solifenacin or salt thereof
US20060198885A1 (en) * 2005-02-22 2006-09-07 Sun Pharmaceutical Industries Ltd. Oral pharmaceutical composition
US7815939B2 (en) * 2005-07-20 2010-10-19 Astellas Pharma Inc. Coated fine particles containing drug for intrabuccally fast disintegrating dosage forms
WO2007010930A1 (ja) * 2005-07-20 2007-01-25 Astellas Pharma Inc. 口腔内崩壊製剤用の薬物含有被覆微粒子及びその製造方法
US20070077300A1 (en) 2005-09-30 2007-04-05 Wynn David W Oral compositions containing a salivation inducing agent
WO2010060635A2 (en) * 2008-11-28 2010-06-03 Krka, D.D., Novo Mesto Solid pharmaceutical composition comprising at least one stabilizing agent
CA2748783A1 (en) * 2009-01-05 2010-07-08 Mcneil-Ppc, Inc. Three layer tablet containing cetirizine, pseudoephedrine, and naproxen
CA2748728C (en) * 2009-01-05 2017-01-03 Mcneil-Ppc, Inc. Tablet containing cetirizine, pseudoephedrine, and naproxen containing a barrier layer
CA2750196C (en) * 2009-01-05 2017-06-20 Mcneil-Ppc, Inc. Tablet containing coated particles of cetirizine, pseudoephedrine, and/or naproxen
WO2011041414A1 (en) * 2009-09-30 2011-04-07 Acura Pharmaceuticals, Inc. Methods and compositions for deterring abuse
KR101765357B1 (ko) 2009-12-02 2017-08-04 아데어 파마수티컬스 에스.알.엘. 펙소페나딘 마이크로캡슐 및 그것을 함유하는 조성물
US20120276177A1 (en) * 2009-12-23 2012-11-01 Colgate-Palmolive Company Visually patterned and oriented compositions
US9149959B2 (en) 2010-10-22 2015-10-06 Monosol Rx, Llc Manufacturing of small film strips
UA114469C2 (uk) 2010-11-01 2017-06-26 Мелінта Терап'Ютікс, Інк. Фармацевтична композиція, що містить протимікробний агент
WO2012170883A1 (en) * 2011-06-09 2012-12-13 Discovery Pharma Consulting, Llc Antihistamines combined with dietary supplements for improved health
PT2802311T (pt) 2011-10-25 2019-03-19 Expermed S A Composição farmacêutica sublingual contendo um agente anti-histamínico e método para a sua preparação
US20130177646A1 (en) * 2012-01-05 2013-07-11 Mcneil Ab Solid Nicotine-Comprising Dosage Form with Reduced Organoleptic Disturbance
WO2014085599A1 (en) 2012-11-30 2014-06-05 Acura Pharmaceuticals, Inc. Self-regulated release of active pharmaceutical ingredient
DK3003285T3 (en) * 2013-06-03 2022-04-04 Mcneil Ab Fast farmaceutisk dosisform til frigivelse af mindst to aktive farmaceutiske ingredienser i mundhulen
SG11201604507RA (en) * 2013-12-04 2016-07-28 Hovione Scientia Ltd Contrast media taste masking formulations
JP6521874B2 (ja) * 2014-02-12 2019-05-29 沢井製薬株式会社 フィルムコーティングされた口腔内崩壊錠
US9642811B2 (en) 2014-03-26 2017-05-09 Sun Pharma Advanced Research Company Ltd. Abuse deterrent immediate release biphasic matrix solid dosage form
US11103581B2 (en) 2015-08-31 2021-08-31 Acura Pharmaceuticals, Inc. Methods and compositions for self-regulated release of active pharmaceutical ingredient
WO2017151571A1 (en) * 2016-02-29 2017-09-08 First Time Us Generics Llc Abuse deterrent soft chewable drug formulations
JP7653218B2 (ja) 2016-05-05 2025-03-28 アクエスティブ セラピューティクス インコーポレイテッド 送達増強エピネフリン組成物
US12427121B2 (en) 2016-05-05 2025-09-30 Aquestive Therapeutics, Inc. Enhanced delivery epinephrine compositions
US11273131B2 (en) 2016-05-05 2022-03-15 Aquestive Therapeutics, Inc. Pharmaceutical compositions with enhanced permeation
US12433850B2 (en) 2016-05-05 2025-10-07 Aquestive Therapeutics, Inc. Enhanced delivery epinephrine and prodrug compositions
MX386983B (es) * 2016-07-05 2025-03-19 Glaxosmithkline Consumer Healthcare Holdings Us Llc Forma de dosificación oral que contiene un revestimiento exterior de liberación rápida
IL262768B (en) * 2018-11-04 2020-08-31 Ambrosia Supherb Ltd A chewable tablet and method of preparing the same
US12465564B2 (en) 2021-10-25 2025-11-11 Aquestive Therapeutics, Inc. Oral and nasal compositions and methods of treatment
US12303604B1 (en) 2024-10-16 2025-05-20 Currax Pharmaceuticals Llc Pharmaceutical formulations comprising naltrexone and/or bupropion

Family Cites Families (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3431138A (en) * 1967-07-14 1969-03-04 American Cyanamid Co Method for coating pharmaceutical forms with methyl cellulose
JPS5535031A (en) * 1978-09-04 1980-03-11 Shin Etsu Chem Co Ltd Enteric coating composition
US4309405A (en) * 1979-08-09 1982-01-05 American Home Products Corporation Sustained release pharmaceutical compositions
US4749575A (en) * 1983-10-03 1988-06-07 Bio-Dar Ltd. Microencapsulated medicament in sweet matrix
JPS61174940A (ja) * 1985-01-29 1986-08-06 Oogawara Kakoki Kk ワックス類コーテイング単核状マイクロカプセルおよびその製造方法
EP0254259A3 (en) * 1986-07-21 1989-11-23 Otsuka Pharmaceutical Factory, Inc. P-aminophenol derivatives
US4800087A (en) * 1986-11-24 1989-01-24 Mehta Atul M Taste-masked pharmaceutical compositions
DK130287D0 (da) * 1987-03-13 1987-03-13 Benzon As Alfred Oralt praeparat
US4916161A (en) * 1988-10-25 1990-04-10 Bristol-Myers Squibb Taste-masking pharmaceutical agents
US5372823A (en) * 1989-03-16 1994-12-13 Bristol-Myers Squibb Company Direct compression cholestyramine tablet and solvent-free coating thereof
US5215999A (en) * 1990-03-28 1993-06-01 Otsuka Pharmaceutical Co., Ltd. Quinoline derivative and antiulcer agent containing said quinoline derivative
IT1246383B (it) * 1990-04-17 1994-11-18 Eurand Int Metodo per il mascheramento del sapore di farmaci
US5075114A (en) * 1990-05-23 1991-12-24 Mcneil-Ppc, Inc. Taste masking and sustained release coatings for pharmaceuticals
EP0458751A1 (en) * 1990-05-25 1991-11-27 Warner-Lambert Company Delivery system for cyclic amino acids with improved taste, texture and compressibility
GB9114184D0 (en) * 1991-07-01 1991-08-21 Unilever Plc Detergent composition
US5837277A (en) * 1992-06-04 1998-11-17 Smithkline Beecham Corporation Palatable pharmaceutical compositions
IT1264020B (it) * 1993-01-28 1996-09-09 Recordati Chem Pharm Procedimento per la preparazione di microgranuli idonei alla sospensione in liquidi
PT621032E (pt) * 1993-04-23 2001-01-31 Novartis Ag Dispositivo de distribuicao de libertacao controlada de farmaco
CA2161538A1 (en) * 1993-07-22 1995-02-02 S. Shirley Yang Controlled release tacrine drug delivery systems and methods for preparing same
ZA945944B (en) * 1993-08-13 1996-02-08 Eurand America Inc Procedure for encapsulating nsaids
JPH07223970A (ja) * 1994-02-10 1995-08-22 Tanabe Seiyaku Co Ltd 消化管内適所放出製剤
US5958458A (en) * 1994-06-15 1999-09-28 Dumex-Alpharma A/S Pharmaceutical multiple unit particulate formulation in the form of coated cores
US5536507A (en) * 1994-06-24 1996-07-16 Bristol-Myers Squibb Company Colonic drug delivery system
US5681382A (en) * 1995-08-22 1997-10-28 Shin-Etsu Chemical Co., Ltd. Rapidly soluble coating composition and method for preparing same
US5789014A (en) * 1995-12-25 1998-08-04 Shin-Etsu Chemical Co., Ltd. Method of manufacturing a solid preparation coated with non-solvent coating
SE507471C2 (sv) * 1996-08-09 1998-06-08 Sunds Defibrator Ind Ab Silpanel samt sätt för dess framställning
HUP0000116A3 (en) * 1996-10-01 2000-08-28 Stanford Res Inst Int Taste-masked microcapsule compositions and methods of manufacture
US6046177A (en) * 1997-05-05 2000-04-04 Cydex, Inc. Sulfoalkyl ether cyclodextrin based controlled release solid pharmaceutical formulations
US6090401A (en) * 1999-03-31 2000-07-18 Mcneil-Ppc, Inc. Stable foam composition
US7223421B2 (en) * 2000-06-30 2007-05-29 Mcneil-Ppc, Inc. Teste masked pharmaceutical particles

Also Published As

Publication number Publication date
HK1045817A1 (en) 2002-12-13
CA2365844A1 (en) 2002-06-21
MXPA02000277A (es) 2004-05-21
KR20020050754A (ko) 2002-06-27
CO5390070A1 (es) 2004-04-30
JP2002272817A (ja) 2002-09-24
AU9736101A (en) 2002-06-27
ATE405250T1 (de) 2008-09-15
CN100544705C (zh) 2009-09-30
CN1366878A (zh) 2002-09-04
BR0106912A (pt) 2003-09-16
CA2365844C (en) 2010-07-06
NZ516341A (en) 2003-08-29
ZA200110547B (en) 2003-07-30
AU783593B2 (en) 2005-11-10
HK1045817B (en) 2009-06-05
DE60135435D1 (de) 2008-10-02
EP1219291A1 (en) 2002-07-03
EP1219291B1 (en) 2008-08-20
ES2311007T3 (es) 2009-02-01
US20120251623A1 (en) 2012-10-04
US20020119196A1 (en) 2002-08-29
HK1046865A1 (zh) 2003-01-30

Similar Documents

Publication Publication Date Title
BR0106912A (pt) Partìculas contendo ingrediente ativo
AR029546A1 (es) Particulas farmaceuticas con sabor enmascarado
AR099567A2 (es) Formulación de tableta revestida que comprende saxagliptina y método de preparación
WO2004056337A3 (en) Oral dosage forms with therapeutically active agents in controlled release cores and immediate release gelatin capsule coats
AR042517A1 (es) Un nucleo absorbente para usar en un articulo absorbente y el proceso para hacer dicho nucleo
MXPA06000852A (es) Peliculas que se disuelven oralmente.
UY26876A1 (es) Forma de dosificación de fármaco activada por hidrogel
AR024384A1 (es) UNA FORMA DE DOSIFICACIoN FARMACÉUTICA DE DISOLUCIoN INSTANTÁNEA Y UN MÉTODO PARA PREPARARLA
NO20016108L (no) Kontrollert frigivelse og smaks maskerende orale farmasöytiske sammensetninger
ES2107235T3 (es) Tableta de liberacion prolongada, revestida con pelicula, de astemizol y pseudoefedrina.
ES2157297T3 (es) Granulos entericos de duloxetina.
WO2008011169A3 (en) Controlled release formulations and associated methods
DE60328008D1 (de) Tablettenförmiges süsswarenprodukt mit dreifachbeschichtung
WO2007103557A3 (en) Coating capsules with active pharmaceutical ingredients
DE60336806D1 (de) Blister-karte für pharmazeutische behandlung
WO2005009410A3 (en) Pharmaceutical compositions having a swellable coating
WO2007041367A3 (en) Oral composition containing a salivation inducing agent
PA8802901A1 (es) Recubrimiento mejorado de tableta
DE60102590D1 (de) Darreichungsformen zur behandlung von oralen mykosen
AR065342A1 (es) Composiciones farmaceuticas que contienen fumarato de quetiapina
WO2006071674A3 (en) Oral care compositions containing a eucalyptus extract
TNSN07203A1 (en) Pharmaceutical compositions for the treatment of cellulite
EP1731609A4 (en) INHIBITOR OF THE EXPRESSION OF RAD51, MEDICAMENT CONTAINING THE INHIBITOR AS ACTIVE INGREDIENT AND USE THEREOF
JP2005526061A5 (es)
ES2421379T3 (es) Composición terapéutica aromatizada a base de arcilla

Legal Events

Date Code Title Description
FB Suspension of granting procedure