BR112012016201A2 - ''composto, processo para a preparação de um composto, composição farmacêutica e uso de um composto'' - Google Patents
''composto, processo para a preparação de um composto, composição farmacêutica e uso de um composto''Info
- Publication number
- BR112012016201A2 BR112012016201A2 BR112012016201A BR112012016201A BR112012016201A2 BR 112012016201 A2 BR112012016201 A2 BR 112012016201A2 BR 112012016201 A BR112012016201 A BR 112012016201A BR 112012016201 A BR112012016201 A BR 112012016201A BR 112012016201 A2 BR112012016201 A2 BR 112012016201A2
- Authority
- BR
- Brazil
- Prior art keywords
- compound
- preparing
- pharmaceutical composition
- pharmaceutical
- composition
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title 3
- 238000004519 manufacturing process Methods 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
- C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/46—8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurology (AREA)
- General Health & Medical Sciences (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Psychology (AREA)
- Child & Adolescent Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Addiction (AREA)
- Anesthesiology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Emergency Medicine (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN3195CH2009 | 2009-12-29 | ||
| PCT/IN2010/000285 WO2011080751A2 (en) | 2009-12-29 | 2010-05-03 | α4β2 NEURONAL NICOTINIC ACETYLCHOLINE RECEPTOR LIGANDS |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR112012016201A2 true BR112012016201A2 (pt) | 2017-12-19 |
Family
ID=43608767
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112012016201A BR112012016201A2 (pt) | 2009-12-29 | 2010-05-03 | ''composto, processo para a preparação de um composto, composição farmacêutica e uso de um composto'' |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US8653071B2 (pt) |
| EP (1) | EP2519514B1 (pt) |
| JP (1) | JP5588018B2 (pt) |
| KR (1) | KR101410903B1 (pt) |
| CN (1) | CN102753540B (pt) |
| AU (1) | AU2010337837B2 (pt) |
| BR (1) | BR112012016201A2 (pt) |
| CA (1) | CA2785957C (pt) |
| DK (1) | DK2519514T3 (pt) |
| EA (1) | EA023293B1 (pt) |
| ES (1) | ES2552932T3 (pt) |
| IL (1) | IL220299A (pt) |
| MX (1) | MX2012006909A (pt) |
| NZ (1) | NZ601088A (pt) |
| SG (1) | SG181502A1 (pt) |
| WO (1) | WO2011080751A2 (pt) |
| ZA (1) | ZA201204562B (pt) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2014028829A1 (en) * | 2012-08-16 | 2014-02-20 | The Scripps Research Institute | Novel kappa opioid ligands |
| CN103467360A (zh) * | 2013-09-09 | 2013-12-25 | 嘉兴学院 | 具有环丙烷结构r-脯氨酸的吗啉衍生物及其制备方法 |
| CN103450073A (zh) * | 2013-09-09 | 2013-12-18 | 嘉兴学院 | 具有环丙烷结构r-二苯基脯氨醇类手性有机小分子化合物及其合成方法 |
| CN103435533A (zh) * | 2013-09-09 | 2013-12-11 | 嘉兴学院 | 具有环丙烷结构的s-脯氨醇手性有机小分子化合物及其合成方法 |
| CN103450074A (zh) * | 2013-09-09 | 2013-12-18 | 嘉兴学院 | 具有环丙烷结构的r-脯氨醇手性有机小分子化合物及其合成方法 |
| CN103435536A (zh) * | 2013-09-09 | 2013-12-11 | 嘉兴学院 | 具有环丙烷结构s-脯氨酸的吡咯衍生物及其制备方法 |
| CN103450072A (zh) * | 2013-09-09 | 2013-12-18 | 嘉兴学院 | 具有环丙烷结构r-脯氨酸的吡咯衍生物及其制备方法 |
| CN103467362A (zh) * | 2013-09-09 | 2013-12-25 | 嘉兴学院 | 具有环丙烷结构s-二苯基脯氨醇类手性有机小分子化合物及其合成方法 |
| CN103467361A (zh) * | 2013-09-09 | 2013-12-25 | 嘉兴学院 | 具有环丙烷结构s-脯氨酸的吗啉衍生物及其制备方法 |
| EP3297676A2 (en) | 2015-05-22 | 2018-03-28 | Helmholtz Zentrum München - Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH) | Combination of trpm8-agonist and nachr-agonist for treatment of obesity and related disorders and for weight reduction |
| EP3676261B1 (en) * | 2017-09-01 | 2024-12-18 | Chronos Therapeutics Limited | Substituted 2-azabicyclo[3.1.1]heptane and 2-azabicyclo[3.2.1]octane derivatives as orexin receptor antagonists |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FI95572C (fi) | 1987-06-22 | 1996-02-26 | Eisai Co Ltd | Menetelmä lääkeaineena käyttökelpoisen piperidiinijohdannaisten tai sen farmaseuttisen suolan valmistamiseksi |
| AU2001272476A1 (en) | 2000-06-16 | 2001-12-24 | Smithkline Beecham Plc | Piperidines for use as orexin receptor antagonists |
| US7164024B2 (en) * | 2001-04-20 | 2007-01-16 | Banyu Pharmaceutical Co., Ltd. | Benzimidazolone derivatives |
| WO2002089800A2 (en) | 2001-05-05 | 2002-11-14 | Smithkline Beecham P.L.C. | N-aroyl cyclic amine derivatives as orexin receptor antagonists |
| GB0225884D0 (en) * | 2002-11-06 | 2002-12-11 | Glaxo Group Ltd | Novel compounds |
| CL2007002809A1 (es) * | 2006-09-29 | 2008-04-18 | Actelion Pharmaceuticals Ltd | Compuestos derivados de 3-aza biciclo [3.1.0]hexano; y su uso en el tratamiento de enfermedades tales como desordenes psicoticos y de ansiedad, desordenes del sueno, uso y abuso de sustancias psicoactivas, demencia y deterioro de funciones cognitivas |
| TWI454262B (zh) | 2006-11-02 | 2014-10-01 | Targacept Inc | 菸鹼乙醯膽鹼受體亞型選擇性之二氮雜雙環烷類醯胺 |
| TW200833328A (en) * | 2006-12-28 | 2008-08-16 | Actelion Pharmaceuticals Ltd | 2-aza-bicyclo[3.1.0]hexane derivatives |
| KR20100046047A (ko) * | 2007-07-27 | 2010-05-04 | 액테리온 파마슈티칼 리미티드 | 2-아자-비시클로[3.3.0]옥탄 유도체 |
-
2010
- 2010-05-03 CA CA2785957A patent/CA2785957C/en not_active Expired - Fee Related
- 2010-05-03 WO PCT/IN2010/000285 patent/WO2011080751A2/en not_active Ceased
- 2010-05-03 CN CN201080060209.7A patent/CN102753540B/zh not_active Expired - Fee Related
- 2010-05-03 DK DK10750186.8T patent/DK2519514T3/en active
- 2010-05-03 US US13/519,298 patent/US8653071B2/en not_active Expired - Fee Related
- 2010-05-03 EA EA201290582A patent/EA023293B1/ru not_active IP Right Cessation
- 2010-05-03 JP JP2012546559A patent/JP5588018B2/ja not_active Expired - Fee Related
- 2010-05-03 SG SG2012040952A patent/SG181502A1/en unknown
- 2010-05-03 NZ NZ601088A patent/NZ601088A/xx not_active IP Right Cessation
- 2010-05-03 KR KR1020127019604A patent/KR101410903B1/ko not_active Expired - Fee Related
- 2010-05-03 ES ES10750186.8T patent/ES2552932T3/es active Active
- 2010-05-03 MX MX2012006909A patent/MX2012006909A/es active IP Right Grant
- 2010-05-03 EP EP10750186.8A patent/EP2519514B1/en active Active
- 2010-05-03 BR BR112012016201A patent/BR112012016201A2/pt not_active IP Right Cessation
- 2010-05-03 AU AU2010337837A patent/AU2010337837B2/en not_active Ceased
-
2012
- 2012-06-11 IL IL220299A patent/IL220299A/en active IP Right Grant
- 2012-06-20 ZA ZA2012/04562A patent/ZA201204562B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU2010337837B2 (en) | 2013-09-05 |
| AU2010337837A1 (en) | 2012-08-02 |
| US20120322808A1 (en) | 2012-12-20 |
| CA2785957A1 (en) | 2011-07-07 |
| IL220299A0 (en) | 2012-07-31 |
| JP2013515762A (ja) | 2013-05-09 |
| KR20120099139A (ko) | 2012-09-06 |
| JP5588018B2 (ja) | 2014-09-10 |
| WO2011080751A2 (en) | 2011-07-07 |
| MX2012006909A (es) | 2012-07-10 |
| SG181502A1 (en) | 2012-07-30 |
| CN102753540A (zh) | 2012-10-24 |
| EP2519514A2 (en) | 2012-11-07 |
| DK2519514T3 (en) | 2015-11-16 |
| EA023293B1 (ru) | 2016-05-31 |
| CN102753540B (zh) | 2014-01-22 |
| CA2785957C (en) | 2015-06-16 |
| IL220299A (en) | 2014-08-31 |
| ZA201204562B (en) | 2013-02-27 |
| NZ601088A (en) | 2013-08-30 |
| WO2011080751A3 (en) | 2011-08-18 |
| US8653071B2 (en) | 2014-02-18 |
| HK1174913A1 (en) | 2013-06-21 |
| KR101410903B1 (ko) | 2014-06-23 |
| ES2552932T3 (es) | 2015-12-03 |
| EA201290582A1 (ru) | 2012-12-28 |
| EP2519514B1 (en) | 2015-08-26 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
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