BRPI0908738A2 - composto, medicamento, uso de um composto, e, processo para preparar os compostos - Google Patents

composto, medicamento, uso de um composto, e, processo para preparar os compostos

Info

Publication number: BRPI0908738A2
Authority: BR; Brazil
Prior art keywords: compound; drug; preparing; compounds
Prior art date: 2008-03-18

Application number

BRPI0908738A

Other languages

English (en)

Inventor

A M Rensink Agatha

Van Loevezijin Arnold

Stoit Axel

G Kruse Cornelis

Venhorst Jennifer

A W Van Der Neut Martina

De Haan Martin

I Iwema Bakker Wouter

Original Assignee

Abbott Healthcare Products Bv

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2008-03-18

Filing date

2009-03-17

Publication date

2017-06-13

2009-03-17 Application filed by Abbott Healthcare Products Bv filed Critical Abbott Healthcare Products Bv

2017-06-13 Publication of BRPI0908738A2 publication Critical patent/BRPI0908738A2/pt

2017-10-10 Publication of BRPI0908738A8 publication Critical patent/BRPI0908738A8/pt

Links

150000001875 compounds Chemical class 0.000 title 3
239000003814 drug Substances 0.000 title 1
229940079593 drug Drugs 0.000 title 1
238000004519 manufacturing process Methods 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/54—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings condensed with carbocyclic rings or ring systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
- A61K31/4155—1,2-Diazoles non condensed and containing further heterocyclic rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
- A61K31/4162—1,2-Diazoles condensed with heterocyclic ring systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/63—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide
- A61K31/635—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide having a heterocyclic ring, e.g. sulfadiazine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/32—Alcohol-abuse
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/34—Tobacco-abuse
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/06—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/54—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings condensed with carbocyclic rings or ring systems
- C07D231/56—Benzopyrazoles; Hydrogenated benzopyrazoles
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/10—Spiro-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
- C07D491/107—Spiro-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Medicinal Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Epidemiology (AREA)
Psychiatry (AREA)
Addiction (AREA)
Diabetes (AREA)
Pain & Pain Management (AREA)
Hematology (AREA)
Obesity (AREA)
Psychology (AREA)
Emergency Medicine (AREA)
Anesthesiology (AREA)
Hospice & Palliative Care (AREA)
Rheumatology (AREA)
Child & Adolescent Psychology (AREA)
Nutrition Science (AREA)
Endocrinology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Plural Heterocyclic Compounds (AREA)

BRPI0908738A 2008-03-18 2009-03-17 Composto, medicamento, uso de um composto, e, processo para preparar os compostos BRPI0908738A8 (pt)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US3746308P	2008-03-18	2008-03-18
EP08152873		2008-03-18
PCT/EP2009/053133 WO2009115515A1 (en)	2008-03-18	2009-03-17	Arylsulfonyl pyrazoline carboxamidine derivatives as 5-ht6 antagonists

Publications (2)

Publication Number	Publication Date
BRPI0908738A2 true BRPI0908738A2 (pt)	2017-06-13
BRPI0908738A8 BRPI0908738A8 (pt)	2017-10-10

Family

ID=39639064

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BRPI0908738A BRPI0908738A8 (pt)	2008-03-18	2009-03-17	Composto, medicamento, uso de um composto, e, processo para preparar os compostos

Country Status (29)

Country	Link
US (3)	US8563723B2 (pt)
EP (2)	EP2265589B1 (pt)
JP (1)	JP5504252B2 (pt)
KR (1)	KR101623357B1 (pt)
CN (2)	CN104003937A (pt)
AR (1)	AR070898A1 (pt)
AU (1)	AU2009226956C1 (pt)
BR (1)	BRPI0908738A8 (pt)
CA (1)	CA2717922A1 (pt)
CO (1)	CO6290679A2 (pt)
CR (1)	CR11742A (pt)
DK (2)	DK2265589T3 (pt)
DO (2)	DOP2010000276A (pt)
EA (1)	EA023176B1 (pt)
EC (1)	ECSP10010476A (pt)
ES (2)	ES2565184T3 (pt)
HK (1)	HK1201823A1 (pt)
IL (1)	IL207846A0 (pt)
MX (1)	MX2010010299A (pt)
MY (1)	MY155318A (pt)
NZ (1)	NZ587743A (pt)
PH (1)	PH12013502376B1 (pt)
PL (2)	PL2265589T3 (pt)
PT (1)	PT2610247T (pt)
SG (1)	SG183688A1 (pt)
TW (1)	TWI557110B (pt)
UA (1)	UA105629C2 (pt)
WO (1)	WO2009115515A1 (pt)
ZA (1)	ZA201006272B (pt)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AR079935A1 (es) *	2010-01-29	2012-02-29	Abbott Healthcare Products Bv	Sintesis de derivados de pirazolin carboxamidina sustituida
WO2013025805A1 (en) *	2011-08-15	2013-02-21	University Of Utah Research Foundation	Substituted (e)-n'-(1-phenylethylidene) benzohydrazide analogs as histone demethylase inhiitors
EP2925726B1 (en) *	2012-11-16	2016-10-26	Bristol-Myers Squibb Company	Dihydropyrazole gpr40 modulators
MX2015005858A (es)	2012-11-16	2015-09-24	Bristol Myers Squibb Co	Moduladores del receptor acoplado a proteina g (gpr40) de dihidropirazol.
PT2920165T (pt) *	2012-11-16	2016-12-20	Bristol Myers Squibb Co	Moduladores de diidropirazol gpr40
EP3140288B1 (en) *	2014-05-09	2023-01-25	The U.S.A. As Represented By The Secretary, Department Of Health And Human Services	Pyrazole derivatives and their use as cannabinoid receptor mediators
EP3180312B1 (en)	2014-08-12	2019-10-16	Loyola University Of Chicago	Indoline sulfonamide inhibitors of dape and ndm-1 and use of the same
EP3109237A1 (en) *	2015-06-22	2016-12-28	AnaMar AB	Novel 5-ht2 antagonists
CN107460160A (zh) *	2017-08-23	2017-12-12	世贸天阶制药（江苏）有限责任公司	一种cho细胞无血清培养基
US10879709B2 (en)	2018-05-31	2020-12-29	National Taipei University Of Technology	Power management system and operating method thereof
BR112022006791A2 (pt)	2019-10-09	2022-06-28	Bayer Ag	Novos compostos heteroaril-triazol como pesticidas
WO2022013225A1 (en)	2020-07-13	2022-01-20	Precirix N.V.	Antibody fragment against folr1
WO2023203135A1 (en)	2022-04-22	2023-10-26	Precirix N.V.	Improved radiolabelled antibody
JP2025517625A (ja)	2022-05-02	2025-06-10	プレシリックス・ナームローゼ・ベンノートシヤープ	プレターゲティング

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CN1529595A (zh) *	2001-09-21	2004-09-15	��ҩ��޹�˾	具有效cb1-拮抗活性的4,5-2氢-1h-吡唑衍生物
GB0422263D0 (en) *	2004-10-07	2004-11-10	Glaxo Group Ltd	Novel compounds
TWI428334B (zh)	2006-09-22	2014-03-01	Abbvie Bahamas Ltd	作為５-ｈｔ6拮抗劑之磺醯基吡唑及磺醯基吡唑啉的甲脒衍生物

2009
- 2009-03-13 AR ARP090100917A patent/AR070898A1/es unknown
- 2009-03-16 TW TW098108412A patent/TWI557110B/zh not_active IP Right Cessation
- 2009-03-17 UA UAA201012295A patent/UA105629C2/uk unknown
- 2009-03-17 AU AU2009226956A patent/AU2009226956C1/en not_active Ceased
- 2009-03-17 SG SG2012057592A patent/SG183688A1/en unknown
- 2009-03-17 CA CA2717922A patent/CA2717922A1/en not_active Abandoned
- 2009-03-17 JP JP2011500192A patent/JP5504252B2/ja not_active Expired - Fee Related
- 2009-03-17 DK DK09721279.9T patent/DK2265589T3/en active
- 2009-03-17 EA EA201071083A patent/EA023176B1/ru not_active IP Right Cessation
- 2009-03-17 NZ NZ587743A patent/NZ587743A/en not_active IP Right Cessation
- 2009-03-17 ES ES09721279.9T patent/ES2565184T3/es active Active
- 2009-03-17 WO PCT/EP2009/053133 patent/WO2009115515A1/en not_active Ceased
- 2009-03-17 EP EP09721279.9A patent/EP2265589B1/en active Active
- 2009-03-17 DK DK13161112.1T patent/DK2610247T3/en active
- 2009-03-17 PL PL09721279T patent/PL2265589T3/pl unknown
- 2009-03-17 US US12/933,182 patent/US8563723B2/en not_active Expired - Fee Related
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Also Published As

Publication number	Publication date
US9126942B2 (en)	2015-09-08
ES2577867T3 (es)	2016-07-19
DOP2010000276A (es)	2010-11-15
WO2009115515A1 (en)	2009-09-24
HK1201823A1 (en)	2015-09-11
CN104003937A (zh)	2014-08-27
CA2717922A1 (en)	2009-09-24
KR20100136504A (ko)	2010-12-28
US8901108B2 (en)	2014-12-02
UA105629C2 (uk)	2014-06-10
EP2265589A1 (en)	2010-12-29
US20140011775A1 (en)	2014-01-09
AU2009226956C1 (en)	2014-03-06
DK2265589T3 (en)	2016-03-21
PL2265589T3 (pl)	2016-06-30
EP2265589B1 (en)	2016-01-27
AU2009226956A8 (en)	2010-09-23
BRPI0908738A8 (pt)	2017-10-10
TW200942519A (en)	2009-10-16
ECSP10010476A (es)	2010-10-30
JP5504252B2 (ja)	2014-05-28
AU2009226956B2 (en)	2013-05-23
MY155318A (en)	2015-09-30
US8563723B2 (en)	2013-10-22
CN102036967B (zh)	2014-10-15
PH12013502376A1 (en)	2015-01-12
AR070898A1 (es)	2010-05-12
EA201071083A1 (ru)	2011-04-29
CR11742A (es)	2011-03-03
US20110046171A1 (en)	2011-02-24
PH12013502376B1 (en)	2015-01-12
EP2610247A1 (en)	2013-07-03
PL2610247T3 (pl)	2017-02-28
SG183688A1 (en)	2012-09-27
EP2610247B1 (en)	2016-05-25
KR101623357B1 (ko)	2016-05-23
AU2009226956A1 (en)	2009-09-24
NZ587743A (en)	2012-06-29
IL207846A0 (en)	2010-12-30
ES2565184T3 (es)	2016-04-01
JP2011517443A (ja)	2011-06-09
EA023176B1 (ru)	2016-05-31
MX2010010299A (es)	2010-12-15
ZA201006272B (en)	2011-05-25
CO6290679A2 (es)	2011-06-20
TWI557110B (zh)	2016-11-11
DOP2010000277A (es)	2011-01-31
PT2610247T (pt)	2016-07-07
HK1152708A1 (en)	2012-03-09
DK2610247T3 (en)	2016-06-13
CN102036967A (zh)	2011-04-27
US20150051239A1 (en)	2015-02-19

Legal Events

Date	Code	Title	Description
2017-10-10	B25A	Requested transfer of rights approved	Owner name: ABBVIE BAHAMAS LTD. (US)
2018-01-09	B08F	Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]
2018-05-02	B08K	Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

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