BR9103036A - Composto,formulacao farmaceutica e processo para a preparacao do composto - Google Patents

Composto,formulacao farmaceutica e processo para a preparacao do composto

Info

Publication number
BR9103036A
BR9103036A BR919103036A BR9103036A BR9103036A BR 9103036 A BR9103036 A BR 9103036A BR 919103036 A BR919103036 A BR 919103036A BR 9103036 A BR9103036 A BR 9103036A BR 9103036 A BR9103036 A BR 9103036A
Authority
BR
Brazil
Prior art keywords
compound
preparation
pharmaceutical formulation
formulation
pharmaceutical
Prior art date
Application number
BR919103036A
Other languages
English (en)
Inventor
James Jeffry Howbert
Fariborz Mohamadi
Michael Marriott Spees
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of BR9103036A publication Critical patent/BR9103036A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
    • C07D333/18—Radicals substituted by singly bound hetero atoms other than halogen by sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/64—Sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/36—Oxygen or sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/30—Hetero atoms other than halogen
    • C07D333/34—Sulfur atoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrrole Compounds (AREA)
BR919103036A 1990-07-17 1991-07-16 Composto,formulacao farmaceutica e processo para a preparacao do composto BR9103036A (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US55422690A 1990-07-17 1990-07-17

Publications (1)

Publication Number Publication Date
BR9103036A true BR9103036A (pt) 1992-04-28

Family

ID=24212538

Family Applications (1)

Application Number Title Priority Date Filing Date
BR919103036A BR9103036A (pt) 1990-07-17 1991-07-16 Composto,formulacao farmaceutica e processo para a preparacao do composto

Country Status (20)

Country Link
US (1) US5302724A (pt)
EP (1) EP0467613A1 (pt)
JP (1) JPH04234382A (pt)
KR (1) KR920002579A (pt)
CN (1) CN1058401A (pt)
AU (1) AU640499B2 (pt)
BR (1) BR9103036A (pt)
CA (1) CA2047103A1 (pt)
CS (1) CS219291A3 (pt)
FI (1) FI913432A7 (pt)
HU (1) HUT58698A (pt)
IE (1) IE912488A1 (pt)
IL (1) IL98784A0 (pt)
MX (1) MX9100165A (pt)
NO (1) NO912773L (pt)
NZ (1) NZ238911A (pt)
PT (1) PT98320A (pt)
RU (1) RU2022963C1 (pt)
YU (1) YU124291A (pt)
ZA (1) ZA915371B (pt)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5254582A (en) * 1992-02-05 1993-10-19 Eli Lilly And Company Antitumor compositions and methods
US5169860A (en) * 1992-03-13 1992-12-08 Eli Lilly And Company Antitumor compositions and methods of treatment
US5387681A (en) * 1992-08-19 1995-02-07 Eli Lilly And Company Synthesis of bicyclic aromatic sulfonic acids sulfonyl chlorides and sulfonamides
US5300499A (en) * 1992-09-02 1994-04-05 Allergan, Inc. 5-substituted 3-thiophene sulfonamides as antiglaucoma agents
ZA941500B (en) * 1993-03-10 1995-09-04 Lilly Co Eli Antitumor compositions and methods of treatment
RU2155761C2 (ru) * 1995-08-10 2000-09-10 Астра АБ Бициклические производные амидина, способ их получения, фармацевтическая композиция и способ ингибирования синтетазы окиси азота
US5908858A (en) * 1996-04-05 1999-06-01 Sankyo Company, Limited 1,2-diphenylpyrrole derivatives, their preparation and their therapeutic uses
AU709107B2 (en) * 1996-08-22 1999-08-19 Dong Wha Pharmaceutical Industrial Co., Ltd. Arylsulfonylimidazolone derivatives as an antitumor agent
AU4799797A (en) * 1996-10-04 1998-04-24 Eli Lilly And Company Antitumor compositions and methods of treatment
JP4171656B2 (ja) 2001-02-28 2008-10-22 テンプル・ユニバーシティ−オブ・ザ・コモンウェルス・システム・オブ・ハイアー・エデュケイション Ｎ−（アリール）−２−アリールエテンスルホンアミド及びその製薬用途
TWI281916B (en) * 2001-10-25 2007-06-01 Lilly Co Eli Antitumor compounds and methods
US7161031B2 (en) * 2002-02-28 2007-01-09 Temple University - Of The Commonwealth System Of Higher Education Amino-substituted sulfonanilides and derivatives thereof for treating proliferative disorders
CN103450149B (zh) * 2012-06-01 2015-10-14 中国科学院上海有机化学研究所 苯基噻吩磺酰胺类化合物及其制备方法和用途
HUE055755T2 (hu) * 2015-02-16 2021-12-28 Univ Queensland Szulfonolkarmabidok és rokon vegyületeik valamint felhasználásuk
US11339136B2 (en) 2016-04-18 2022-05-24 Novartis Ag Compounds and compositions for treating conditions associated with NLRP activity
KR102669722B1 (ko) 2017-07-07 2024-05-29 인플라좀 리미티드 신규한 설폰아마이드 카복스아마이드 화합물
EP3668843A1 (en) 2017-08-15 2020-06-24 Inflazome Limited Sulfonylureas and sulfonylthioureas as nlrp3 inhibitors
TW201910317A (zh) 2017-08-15 2019-03-16 愛爾蘭商英弗雷佐姆有限公司 新穎化合物
TW201910316A (zh) 2017-08-15 2019-03-16 愛爾蘭商英弗雷佐姆有限公司 新穎化合物
EP3707137A1 (en) 2017-11-09 2020-09-16 Inflazome Limited Novel sulfonamide carboxamide compounds
PE20210050A1 (es) 2017-11-09 2021-01-08 Inflazome Ltd Nuevos compuestos de sulfonamida carboxamida
WO2019166619A1 (en) 2018-03-02 2019-09-06 Inflazome Limited Novel compounds
CN109384764B (zh) * 2018-12-12 2021-09-03 中国科学院上海有机化学研究所 苯基噻吩磺酰胺类化合物、药物组合物、其制备方法和应用

Family Cites Families (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3083207A (en) * 1963-03-26 Indolinesulfonylureas
US3124597A (en) * 1964-03-10
DE1144259B (de) * 1956-05-29 1963-02-28 Hoechst Ag Verfahren zur Herstellung von Sulfonylharnstoffen
US3097241A (en) * 1956-08-10 1963-07-09 Hoechst Ag Nu-cyclohexane-sulphonyl-n'-(beta-phenylethyl)-urea
CH361010A (de) * 1957-05-24 1962-03-31 Geigy Ag J R Verfahren zur Herstellung von N'-substituierten N-Thiophensulfonylharnstoffen
US2979437A (en) * 1958-09-02 1961-04-11 Pfizer & Co C Substituted styryl, and thienylethenyl, pyridylethenyl sulfonylureas and method of treating diabetes
US3013072A (en) * 1958-09-02 1961-12-12 Pfizer & Co C Novel process for the production of sulfonylureas
DE1159937B (de) * 1960-06-29 1963-12-27 Heyden Chem Fab Verfahren zur Herstellung von Hydrindensulfonylharnstoffen
US3097242A (en) * 1960-06-29 1963-07-09 Olin Mathieson Hydrindene sulfonylureas
DE1240866B (de) * 1961-06-29 1967-05-24 Heyden Chem Fab Verfahren zur Herstellung von Indolin-6-sulfonylharnstoffen
US3102121A (en) * 1961-06-29 1963-08-27 Olin Mathieson Novel cumaransulfonylureas and 2,3-dihydrothionaphthenesulfonylureas
US3155721A (en) * 1961-11-30 1964-11-03 Lilly Co Eli Novel sulfonylureas
GB1050447A (pt) * 1962-04-11
US3849110A (en) * 1963-01-07 1974-11-19 Lilly Co Eli Herbicidal method employing aryl-sulfonylureas or salts thereof
US3736122A (en) * 1969-04-10 1973-05-29 C Tung Method of controlling plant growth
US4398939A (en) * 1980-06-03 1983-08-16 E. I. Du Pont De Nemours And Company Herbicidal thiophenesulfonamides
US4634465A (en) * 1982-07-16 1987-01-06 Ciba-Geigy Corporation Fused N-phenylsulfonyl-N'-pyrimidinylureas and N-phenylsulfonyl-N'triazinylureas
AU1862083A (en) * 1982-09-02 1984-03-08 Duphar International Research B.V. Tumor growth inhibitors
US4471757A (en) * 1983-03-15 1984-09-18 Rogers William W Log support for fireplace
IT1161220B (it) * 1983-04-21 1987-03-18 Montedison Spa Diidro-benzofurano derivati ad attivita' erbicida
US4620868A (en) * 1983-12-27 1986-11-04 Ishihara Sangyo Kaisha, Ltd. N-[(4,6-dimethoxypyrimidin-2-yl)aminocarbonyl]-3[halo-substituted ethenyl (or propenyl)]-2-thiophenesulfonamides useful as herbicides
CA1208561A (en) * 1984-01-19 1986-07-29 Marius S. Brouwer Pharmaceutical compositions containing benzoylurea compounds
US4845128A (en) * 1984-06-27 1989-07-04 Eli Lilly And Company N([(4-trifluoromethylphenyl)amino]carbonyl)benzene sulfonamides
US4861366A (en) * 1984-08-27 1989-08-29 E. I. Du Pont De Nemours And Company Herbicidal acetals and ketals
ZA861446B (en) * 1985-03-01 1986-10-29 Duphar Int Res Benzoyl urea derivatives having anti-tumor activity
IL80032A (en) * 1985-09-23 1992-07-15 Lilly Co Eli Anti-tumor phenyl-aminocarbonylsulfonamides,their preparation and pharmaceutical compositions containing them
EP0228237B1 (en) * 1985-12-24 1989-11-23 Merck & Co. Inc. Substituted thiophene-2-sulfonamide antiglaucoma agents
CA1331464C (en) * 1987-05-12 1994-08-16 Eli Lilly And Company Anti-tumor method and compounds

Also Published As

Publication number Publication date
EP0467613A1 (en) 1992-01-22
MX9100165A (es) 1992-02-28
FI913432A0 (fi) 1991-07-16
ZA915371B (en) 1993-03-31
NZ238911A (en) 1993-10-26
AU8044491A (en) 1992-01-23
RU2022963C1 (ru) 1994-11-15
CS219291A3 (en) 1992-09-16
AU640499B2 (en) 1993-08-26
JPH04234382A (ja) 1992-08-24
NO912773D0 (no) 1991-07-15
CN1058401A (zh) 1992-02-05
US5302724A (en) 1994-04-12
CA2047103A1 (en) 1992-01-18
FI913432L (fi) 1992-01-18
PT98320A (pt) 1992-05-29
HUT58698A (en) 1992-03-30
IE912488A1 (en) 1992-01-29
IL98784A0 (en) 1992-07-15
KR920002579A (ko) 1992-02-28
NO912773L (no) 1992-01-20
FI913432A7 (fi) 1992-01-18
HU912375D0 (en) 1991-12-30
YU124291A (sh) 1994-01-20

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Legal Events

Date Code Title Description
FD3 Appl. lapsed due to non-payment of renewal fee