NO912773L - Antitumor-sammensetninger og fremgangsmaater for behandling - Google Patents

Antitumor-sammensetninger og fremgangsmaater for behandling

Info

Publication number
NO912773L
NO912773L NO91912773A NO912773A NO912773L NO 912773 L NO912773 L NO 912773L NO 91912773 A NO91912773 A NO 91912773A NO 912773 A NO912773 A NO 912773A NO 912773 L NO912773 L NO 912773L
Authority
NO
Norway
Prior art keywords
procedures
treatment
antitumor compositions
antitumor
compositions
Prior art date
Application number
NO91912773A
Other languages
English (en)
Other versions
NO912773D0 (no
Inventor
James Jeffry Howbert
Fariborz Mohamadi
Michael Marriott Spees
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of NO912773D0 publication Critical patent/NO912773D0/no
Publication of NO912773L publication Critical patent/NO912773L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
    • C07D333/18—Radicals substituted by singly bound hetero atoms other than halogen by sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/64—Sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/36—Oxygen or sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/30—Hetero atoms other than halogen
    • C07D333/34—Sulfur atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrrole Compounds (AREA)
NO91912773A 1990-07-17 1991-07-15 Antitumor-sammensetninger og fremgangsmaater for behandling NO912773L (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US55422690A 1990-07-17 1990-07-17

Publications (2)

Publication Number Publication Date
NO912773D0 NO912773D0 (no) 1991-07-15
NO912773L true NO912773L (no) 1992-01-20

Family

ID=24212538

Family Applications (1)

Application Number Title Priority Date Filing Date
NO91912773A NO912773L (no) 1990-07-17 1991-07-15 Antitumor-sammensetninger og fremgangsmaater for behandling

Country Status (20)

Country Link
US (1) US5302724A (no)
EP (1) EP0467613A1 (no)
JP (1) JPH04234382A (no)
KR (1) KR920002579A (no)
CN (1) CN1058401A (no)
AU (1) AU640499B2 (no)
BR (1) BR9103036A (no)
CA (1) CA2047103A1 (no)
CS (1) CS219291A3 (no)
FI (1) FI913432L (no)
HU (1) HUT58698A (no)
IE (1) IE912488A1 (no)
IL (1) IL98784A0 (no)
MX (1) MX9100165A (no)
NO (1) NO912773L (no)
NZ (1) NZ238911A (no)
PT (1) PT98320A (no)
RU (1) RU2022963C1 (no)
YU (1) YU124291A (no)
ZA (1) ZA915371B (no)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5254582A (en) * 1992-02-05 1993-10-19 Eli Lilly And Company Antitumor compositions and methods
US5169860A (en) * 1992-03-13 1992-12-08 Eli Lilly And Company Antitumor compositions and methods of treatment
US5387681A (en) * 1992-08-19 1995-02-07 Eli Lilly And Company Synthesis of bicyclic aromatic sulfonic acids sulfonyl chlorides and sulfonamides
US5300499A (en) * 1992-09-02 1994-04-05 Allergan, Inc. 5-substituted 3-thiophene sulfonamides as antiglaucoma agents
ZA941500B (en) * 1993-03-10 1995-09-04 Lilly Co Eli Antitumor compositions and methods of treatment
RU2155761C2 (ru) * 1995-08-10 2000-09-10 Астра АБ Бициклические производные амидина, способ их получения, фармацевтическая композиция и способ ингибирования синтетазы окиси азота
US5908858A (en) * 1996-04-05 1999-06-01 Sankyo Company, Limited 1,2-diphenylpyrrole derivatives, their preparation and their therapeutic uses
AU709107B2 (en) * 1996-08-22 1999-08-19 Dong Wha Pharmaceutical Industrial Co., Ltd. Arylsulfonylimidazolone derivatives as an antitumor agent
EP0929540A4 (en) * 1996-10-04 2001-12-12 Lilly Co Eli ANTI-TUMOR COMPOSITIONS AND THERAPEUTIC METHODS
US6646009B2 (en) 2001-02-28 2003-11-11 Temple University — Of Commonwealth System of Higher Education N-(aryl)-2-arylethenesulfonamides and therapeutic uses thereof
TWI281916B (en) * 2001-10-25 2007-06-01 Lilly Co Eli Antitumor compounds and methods
EP1534284B1 (en) * 2002-02-28 2011-07-27 Temple University - Of The Commonwealth System of Higher Education Amino-substituted sulfonanilides and derivatives thereof for treating proliferative disorders
CN103450149B (zh) * 2012-06-01 2015-10-14 中国科学院上海有机化学研究所 苯基噻吩磺酰胺类化合物及其制备方法和用途
KR102727059B1 (ko) 2015-02-16 2024-11-05 더 유니버서티 어브 퀸슬랜드 설포닐우레아와 관련 화합물 및 그 용도
US11597706B2 (en) 2016-04-18 2023-03-07 Novartis Ag Compounds and compositions for treating conditions associated with NLRP activity
US11465992B2 (en) 2017-07-07 2022-10-11 Inflazome Limited Sulfonamide carboxamide compounds
WO2019034693A1 (en) 2017-08-15 2019-02-21 Inflazome Limited SULFONYLURATES AND SULFONYLTHIOURES AS INHIBITORS OF NLRP3
US11542255B2 (en) 2017-08-15 2023-01-03 Inflazome Limited Sulfonylureas and sulfonylthioureas as NLRP3 inhibitors
MX2020001776A (es) 2017-08-15 2020-03-24 Inflazome Ltd Sulfonilureas y sulfoniltioureas como inhibidores de nlrp3.
US12221434B2 (en) 2017-11-09 2025-02-11 Inflazome Limited Sulfonamide carboxamide compounds
KR20200087759A (ko) 2017-11-09 2020-07-21 인플라좀 리미티드 신규한 설폰아마이드 카복스아마이드 화합물
EP3759077A1 (en) 2018-03-02 2021-01-06 Inflazome Limited Novel compounds
CN109384764B (zh) * 2018-12-12 2021-09-03 中国科学院上海有机化学研究所 苯基噻吩磺酰胺类化合物、药物组合物、其制备方法和应用

Family Cites Families (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3124597A (en) * 1964-03-10
US3083207A (en) * 1963-03-26 Indolinesulfonylureas
DE1144259B (de) * 1956-05-29 1963-02-28 Hoechst Ag Verfahren zur Herstellung von Sulfonylharnstoffen
US3097241A (en) * 1956-08-10 1963-07-09 Hoechst Ag Nu-cyclohexane-sulphonyl-n'-(beta-phenylethyl)-urea
CH361010A (de) * 1957-05-24 1962-03-31 Geigy Ag J R Verfahren zur Herstellung von N'-substituierten N-Thiophensulfonylharnstoffen
US2979437A (en) * 1958-09-02 1961-04-11 Pfizer & Co C Substituted styryl, and thienylethenyl, pyridylethenyl sulfonylureas and method of treating diabetes
US3013072A (en) * 1958-09-02 1961-12-12 Pfizer & Co C Novel process for the production of sulfonylureas
US3097242A (en) * 1960-06-29 1963-07-09 Olin Mathieson Hydrindene sulfonylureas
DE1159937B (de) * 1960-06-29 1963-12-27 Heyden Chem Fab Verfahren zur Herstellung von Hydrindensulfonylharnstoffen
US3102121A (en) * 1961-06-29 1963-08-27 Olin Mathieson Novel cumaransulfonylureas and 2,3-dihydrothionaphthenesulfonylureas
DE1240866B (de) * 1961-06-29 1967-05-24 Heyden Chem Fab Verfahren zur Herstellung von Indolin-6-sulfonylharnstoffen
US3155721A (en) * 1961-11-30 1964-11-03 Lilly Co Eli Novel sulfonylureas
BE634577A (no) * 1962-04-11
US3849110A (en) * 1963-01-07 1974-11-19 Lilly Co Eli Herbicidal method employing aryl-sulfonylureas or salts thereof
US3736122A (en) * 1969-04-10 1973-05-29 C Tung Method of controlling plant growth
US4398939A (en) * 1980-06-03 1983-08-16 E. I. Du Pont De Nemours And Company Herbicidal thiophenesulfonamides
US4634465A (en) * 1982-07-16 1987-01-06 Ciba-Geigy Corporation Fused N-phenylsulfonyl-N'-pyrimidinylureas and N-phenylsulfonyl-N'triazinylureas
IL69621A0 (en) * 1982-09-02 1983-12-30 Duphar Int Res Pharmaceutical compositions having antitumor activity,comprising certain phenylurea derivatives
US4471757A (en) * 1983-03-15 1984-09-18 Rogers William W Log support for fireplace
IT1161220B (it) * 1983-04-21 1987-03-18 Montedison Spa Diidro-benzofurano derivati ad attivita' erbicida
US4620868A (en) * 1983-12-27 1986-11-04 Ishihara Sangyo Kaisha, Ltd. N-[(4,6-dimethoxypyrimidin-2-yl)aminocarbonyl]-3[halo-substituted ethenyl (or propenyl)]-2-thiophenesulfonamides useful as herbicides
CA1208561A (en) * 1984-01-19 1986-07-29 Marius S. Brouwer Pharmaceutical compositions containing benzoylurea compounds
US4845128A (en) * 1984-06-27 1989-07-04 Eli Lilly And Company N([(4-trifluoromethylphenyl)amino]carbonyl)benzene sulfonamides
US4861366A (en) * 1984-08-27 1989-08-29 E. I. Du Pont De Nemours And Company Herbicidal acetals and ketals
IE860511L (en) * 1985-03-01 1986-09-01 Alfa Farmaceutici Spa "Benzoyl urea derivatives having anti-tumor activity"
IL80032A (en) * 1985-09-23 1992-07-15 Lilly Co Eli Anti-tumor phenyl-aminocarbonylsulfonamides,their preparation and pharmaceutical compositions containing them
DE3667056D1 (en) * 1985-12-24 1989-12-28 Merck & Co Inc Substituted thiophene-2-sulfonamide antiglaucoma agents
CA1331464C (en) * 1987-05-12 1994-08-16 Eli Lilly And Company Anti-tumor method and compounds

Also Published As

Publication number Publication date
RU2022963C1 (ru) 1994-11-15
ZA915371B (en) 1993-03-31
YU124291A (sh) 1994-01-20
CA2047103A1 (en) 1992-01-18
IL98784A0 (en) 1992-07-15
FI913432A7 (fi) 1992-01-18
FI913432L (fi) 1992-01-18
KR920002579A (ko) 1992-02-28
MX9100165A (es) 1992-02-28
US5302724A (en) 1994-04-12
HU912375D0 (en) 1991-12-30
CN1058401A (zh) 1992-02-05
EP0467613A1 (en) 1992-01-22
JPH04234382A (ja) 1992-08-24
BR9103036A (pt) 1992-04-28
FI913432A0 (fi) 1991-07-16
NO912773D0 (no) 1991-07-15
HUT58698A (en) 1992-03-30
NZ238911A (en) 1993-10-26
AU8044491A (en) 1992-01-23
CS219291A3 (en) 1992-09-16
AU640499B2 (en) 1993-08-26
IE912488A1 (en) 1992-01-29
PT98320A (pt) 1992-05-29

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