BR9307734A - Formulações injetáveis aquosas úteis para radiodiagnose compreendendo compostos aromáticos iodados usadas como meio de contraste de raio x - Google Patents

Formulações injetáveis aquosas úteis para radiodiagnose compreendendo compostos aromáticos iodados usadas como meio de contraste de raio x

Info

Publication number
BR9307734A
BR9307734A BR9307734-3A BR9307734A BR9307734A BR 9307734 A BR9307734 A BR 9307734A BR 9307734 A BR9307734 A BR 9307734A BR 9307734 A BR9307734 A BR 9307734A
Authority
BR
Brazil
Prior art keywords
radiodiagnosis
iodized
compounds
ray contrast
injectable formulations
Prior art date
Application number
BR9307734-3A
Other languages
English (en)
Inventor
Ernst Felder
Christoph De Haen
Original Assignee
Bracco Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bracco Spa filed Critical Bracco Spa
Publication of BR9307734A publication Critical patent/BR9307734A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/04—X-ray contrast preparations
    • A61K49/0433—X-ray contrast preparations containing an organic halogenated X-ray contrast-enhancing agent
    • A61K49/0447—Physical forms of mixtures of two different X-ray contrast-enhancing agents, containing at least one X-ray contrast-enhancing agent which is a halogenated organic compound
    • A61K49/0452—Solutions, e.g. for injection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/04—X-ray contrast preparations
    • A61K49/0433—X-ray contrast preparations containing an organic halogenated X-ray contrast-enhancing agent
    • A61K49/0447—Physical forms of mixtures of two different X-ray contrast-enhancing agents, containing at least one X-ray contrast-enhancing agent which is a halogenated organic compound

Landscapes

  • Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Patente de Invenção:<B>"FORMULAçõES INJETáVEIS AQUOSAS úTEIS PARA RADIODIAGNOSE COMPREENDENDO COMPOSTOS AROMáTICOS IODADOS USADAS COMO MEIO DE CONTRASTE DE RAIOS X"<D>. Esta invenção refere-se a formulações aquosas injetáveis contendo agentes de contraste radiopacos úteis para formação de imagens de raios X de corpo humano ou animal. Esta invenção especialmente trata de soluções aquosas injetáveis de misturas de compostos aromáticos iodados solúveis em água e não-iónicos, de preferência, constituídos por: a) compostos compreendendo um núcleo aromático pelo menos triiodo-substituído; b) compostos compreendendo pelo menos dois núcleos aromáticos variavelmente ligados entre si, cada um pelo menos triiodo-substituído.
BR9307734-3A 1992-12-24 1993-12-20 Formulações injetáveis aquosas úteis para radiodiagnose compreendendo compostos aromáticos iodados usadas como meio de contraste de raio x BR9307734A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ITMI922964A IT1256248B (it) 1992-12-24 1992-12-24 Formulazioni iniettabili acquose per radiodiagnostica comprendenti miscele di composti aromatici iodurati utili come agenti opacizzanti ai raggi x
PCT/EP1993/003613 WO1994014478A1 (en) 1992-12-24 1993-12-20 Aqueous injectable formulations useful for radio-diagnosis comprising iodinated aromatic compounds used as x-ray contrast media

Publications (1)

Publication Number Publication Date
BR9307734A true BR9307734A (pt) 1999-08-31

Family

ID=11364538

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9307734-3A BR9307734A (pt) 1992-12-24 1993-12-20 Formulações injetáveis aquosas úteis para radiodiagnose compreendendo compostos aromáticos iodados usadas como meio de contraste de raio x

Country Status (22)

Country Link
US (1) US5695742A (pt)
EP (1) EP0675738B1 (pt)
JP (1) JP3585233B2 (pt)
CN (1) CN1100329A (pt)
AT (1) ATE166234T1 (pt)
AU (1) AU5833294A (pt)
BR (1) BR9307734A (pt)
CA (1) CA2152480A1 (pt)
CZ (1) CZ165595A3 (pt)
DE (2) DE675738T1 (pt)
ES (1) ES2077554T1 (pt)
FI (1) FI953124L (pt)
GR (1) GR950300061T1 (pt)
HU (1) HUT72304A (pt)
IL (1) IL108158A0 (pt)
IS (1) IS4114A (pt)
IT (1) IT1256248B (pt)
MX (1) MX9400185A (pt)
NO (1) NO952533L (pt)
PL (1) PL309395A1 (pt)
WO (1) WO1994014478A1 (pt)
ZA (1) ZA939666B (pt)

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IT1256248B (it) * 1992-12-24 1995-11-29 Bracco Spa Formulazioni iniettabili acquose per radiodiagnostica comprendenti miscele di composti aromatici iodurati utili come agenti opacizzanti ai raggi x
US5686061A (en) * 1994-04-11 1997-11-11 The Board Of Regents Of The University Of Texas System Particulate contrast media derived from non-ionic water soluble contrast agents for CT enhancement of hepatic tumors
GB9419206D0 (en) * 1994-09-23 1994-11-09 Nycomed Innovation Ab Contrast media
GB9419203D0 (en) * 1994-09-23 1994-11-09 Nycomed Innovation Ab Contrast media
US5575905A (en) * 1995-05-24 1996-11-19 Nycomed Imaging As Iodination process
WO1997000240A1 (en) * 1995-06-16 1997-01-03 Biophysica Foundation Formyl derivatives as nonionic contrast media
PL328199A1 (en) 1996-01-25 1999-01-18 Schering Ag Improved concentrated intravascular injection and infusion solutions
DE19648650C2 (de) * 1996-01-29 1998-07-02 Schering Ag Puffersysteme und deren Verwendung zur Stabilisierung pharmazeutischer Zubereitung
DE19627309C2 (de) * 1996-06-27 1999-07-29 Schering Ag Wäßrige injizierbare Formulierungen verwendbar als Kontrastmittel
DE19736472C1 (de) * 1997-08-21 1999-04-22 Bernhard Dr Sixt Verfahren zum Herstellen von weitgehend nebenwirkungsfreien Kontrastmitteln
US6406680B1 (en) * 1999-09-17 2002-06-18 Nycomed Imaging As X-ray contrast agents
SE520688C2 (sv) 2000-04-11 2003-08-12 Bone Support Ab Ett injicerbart ersättningsmaterial för benmineral
SE517168C2 (sv) 2000-07-17 2002-04-23 Bone Support Ab En komposition för ett injicerbart ersättningsmaterial för benmineral
US6832220B1 (en) * 2000-08-03 2004-12-14 Microsoft Corporation Method and apparatus for file searching, accessing file identifiers from reference page
SE522098C2 (sv) 2001-12-20 2004-01-13 Bone Support Ab Ett nytt benmineralsubstitut
AU2002359206B2 (en) 2001-12-20 2008-04-10 Bone Support Ab A new bone mineral substitute
GB0228410D0 (en) 2002-12-05 2003-01-08 Glaxo Group Ltd Novel Compounds
SE0300620D0 (sv) 2003-03-05 2003-03-05 Bone Support Ab A new bone substitute composition
SE0302983D0 (sv) 2003-11-11 2003-11-11 Bone Support Ab Anordning för att förse spongiöst ben med benersättnings- och/eller benförstärkningsmaterial och förfarande i samband därmed
CN1938050A (zh) 2004-03-11 2007-03-28 马林克罗特公司 包含碘代单体以及二聚体混合物的x射线造影制剂
SE527528C2 (sv) 2004-06-22 2006-04-04 Bone Support Ab Anordning för framställning av härdbar massa samt användning av anordningen
FR2899581B1 (fr) * 2006-04-07 2008-06-27 Guerbet Sa Procede d'atomisation du ioxilan
WO2009005365A1 (en) * 2007-06-29 2009-01-08 Ge Healthcare As Contrast agents
CN103951586B (zh) 2007-07-12 2015-05-27 通用电气医疗集团股份有限公司 造影剂
JP2011500533A (ja) * 2007-10-12 2011-01-06 ジーイー・ヘルスケア・アクスイェ・セルスカプ 造影剤
US20100209356A1 (en) * 2007-10-12 2010-08-19 Duncan George Wynn Contrast agents
WO2009071605A1 (en) * 2007-12-05 2009-06-11 Ge Healthcare As Contrast agents
EP2247314A4 (en) * 2008-02-01 2013-11-27 Univ Boston CATIONIC CONTRASTING AGENTS AND METHOD FOR THEIR USE
EP2093206A1 (en) 2008-02-20 2009-08-26 BRACCO IMAGING S.p.A. Process for the iodination of aromatic compounds
WO2009106552A2 (en) * 2008-02-27 2009-09-03 Ge Healthcare As Contrast agents
EP2245004A2 (en) * 2008-02-27 2010-11-03 GE Healthcare AS Contrast agents
WO2010060941A2 (en) * 2008-11-27 2010-06-03 Ge Healthcare As Contrast agents
EP2385845A1 (en) * 2009-01-09 2011-11-16 Ge Healthcare As Contrast media compositions
EP2230227A1 (en) 2009-03-20 2010-09-22 Bracco Imaging S.p.A Process for the preparation of triiodinated carboxylic aromatic derivatives
EP2243767A1 (en) 2009-04-21 2010-10-27 Bracco Imaging S.p.A Process for the iodination of aromatic compounds
JP5661762B2 (ja) 2009-07-07 2015-01-28 ブラッコ・イメージング・ソシエタ・ペル・アチオニＢｒａｃｃｏ Ｉｍａｇｉｎｇ Ｓ．Ｐ．Ａ． ヨウ素化剤の製造方法
US9180137B2 (en) 2010-02-09 2015-11-10 Bone Support Ab Preparation of bone cement compositions
DK2958603T3 (en) 2013-02-20 2018-07-16 Bone Support Ab IMPROVED CURE FOR HARDWARE BONE COMPENSATION
JP6425375B2 (ja) * 2013-10-11 2018-11-21 新光電気工業株式会社 コイル基板及びその製造方法、インダクタ
WO2016123583A1 (en) 2015-01-29 2016-08-04 Theracell, Inc. Demineralized bone fiber composition for use in minimally invasive surgery
WO2018104228A1 (en) 2016-12-05 2018-06-14 Bracco Imaging Spa Mechanochemical synthesis of radiographic agents intermediates
US10639157B2 (en) 2017-03-14 2020-05-05 Theracell, Inc. Demineralized bone fiber composition for use in minimally invasive surgery
EP4514771B1 (en) 2022-04-29 2026-04-15 Bracco Imaging SPA Process for the preparation of 2,4,6-triiodophenol derivatives
EP4704924A1 (en) 2023-04-23 2026-03-11 Translational And Fundamental Technologies Institute Llc Radionuclide-loaded nanoparticles for focal tissue ablation

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US2613172A (en) * 1949-08-10 1952-10-07 American Cystoscope Makers Inc X-ray contrast compositions
CH608189A5 (pt) * 1974-12-13 1978-12-29 Savac Ag
NL8002388A (nl) * 1979-05-21 1980-11-25 Mallinckrodt Inc Roentgencontrastmiddel.
FR2511871A1 (fr) * 1981-08-28 1983-03-04 Guerbet Sa Procede pour augmenter la tolerance des produits opacifiants et produits opacifiants ainsi obtenus
GB8906130D0 (en) * 1989-03-17 1989-05-04 Nycomed As Compositions
US5075502A (en) * 1989-12-13 1991-12-24 Mallinckrodt, Inc. Nonionic x-ray contrast agents, compositions and methods
US5191120A (en) * 1989-12-13 1993-03-02 Mallinckrodt Medical, Inc. Process for preparing nonionic X-ray contrast agents
GB9020091D0 (en) * 1990-09-14 1990-10-24 Nycomed As Contrast media
WO1994005337A1 (en) * 1992-09-02 1994-03-17 Mallinckrodt Medical, Inc. Nonionic x-ray contrast agents, compositions and methods
US5260478A (en) * 1992-12-08 1993-11-09 Sterling Winthrop Inc. Iodinated aroyloxy carboxamides
NZ250063A (en) * 1992-12-14 1996-03-26 Eastman Kodak Co Iodinated aromatic acid ester derivatives; x-ray contrast compositions
IT1256248B (it) * 1992-12-24 1995-11-29 Bracco Spa Formulazioni iniettabili acquose per radiodiagnostica comprendenti miscele di composti aromatici iodurati utili come agenti opacizzanti ai raggi x

Also Published As

Publication number Publication date
ES2077554T1 (es) 1995-12-01
ATE166234T1 (de) 1998-06-15
CA2152480A1 (en) 1994-07-07
ITMI922964A0 (it) 1992-12-24
JP3585233B2 (ja) 2004-11-04
JPH08505134A (ja) 1996-06-04
WO1994014478A1 (en) 1994-07-07
ITMI922964A1 (it) 1994-06-24
CN1100329A (zh) 1995-03-22
MX9400185A (es) 1994-07-29
DE69318727T2 (de) 1998-09-17
FI953124A7 (fi) 1995-06-22
IT1256248B (it) 1995-11-29
AU5833294A (en) 1994-07-19
IL108158A0 (en) 1994-04-12
PL309395A1 (en) 1995-10-02
IS4114A (is) 1994-06-25
CZ165595A3 (en) 1995-12-13
NO952533D0 (no) 1995-06-23
US5695742A (en) 1997-12-09
ZA939666B (en) 1994-08-29
DE675738T1 (de) 1996-02-29
DE69318727D1 (de) 1998-06-25
NO952533L (no) 1995-08-16
EP0675738A1 (en) 1995-10-11
FI953124A0 (fi) 1995-06-22
HU9501850D0 (en) 1995-08-28
GR950300061T1 (en) 1995-11-30
HUT72304A (en) 1996-04-29
EP0675738B1 (en) 1998-05-20
FI953124L (fi) 1995-06-22

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Legal Events

Date Code Title Description
EG Technical examination (opinion): publication of technical examination (opinion)
FC Decision: refusal