BR9713675A - Dispositivo de administração local de formulações sólidas ou semi - sólidas, formulações retardo para administração parenteral e processo de preparo - Google Patents
Dispositivo de administração local de formulações sólidas ou semi - sólidas, formulações retardo para administração parenteral e processo de preparoInfo
- Publication number
- BR9713675A BR9713675A BR9713675-1A BR9713675A BR9713675A BR 9713675 A BR9713675 A BR 9713675A BR 9713675 A BR9713675 A BR 9713675A BR 9713675 A BR9713675 A BR 9713675A
- Authority
- BR
- Brazil
- Prior art keywords
- solid
- semi
- formulations
- active ingredient
- administration
- Prior art date
Links
- 239000007787 solid Substances 0.000 title abstract 11
- 239000000203 mixture Substances 0.000 title abstract 7
- 238000009472 formulation Methods 0.000 title abstract 5
- 238000007911 parenteral administration Methods 0.000 title abstract 2
- 238000002360 preparation method Methods 0.000 title abstract 2
- 230000003111 delayed effect Effects 0.000 title 1
- 239000004480 active ingredient Substances 0.000 abstract 4
- 238000003780 insertion Methods 0.000 abstract 3
- 230000037431 insertion Effects 0.000 abstract 3
- 238000002347 injection Methods 0.000 abstract 2
- 239000007924 injection Substances 0.000 abstract 2
- 230000003213 activating effect Effects 0.000 abstract 1
- 230000003750 conditioning effect Effects 0.000 abstract 1
- 230000008021 deposition Effects 0.000 abstract 1
- 239000008240 homogeneous mixture Substances 0.000 abstract 1
- 239000007943 implant Substances 0.000 abstract 1
- 238000004806 packaging method and process Methods 0.000 abstract 1
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61D—VETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
- A61D7/00—Devices or methods for introducing solid, liquid, or gaseous remedies or other materials into or onto the bodies of animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0069—Devices for implanting pellets, e.g. markers or solid medicaments
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Dermatology (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Hematology (AREA)
- Heart & Thoracic Surgery (AREA)
- Medical Informatics (AREA)
- Anesthesiology (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurosurgery (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Surgical Instruments (AREA)
- Endoscopes (AREA)
- Media Introduction/Drainage Providing Device (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
Abstract
Patente de Invenção: <B>"DISPOSITIVO DE ADMINISTRAçãO LOCAL DE FORMULAçõES SóLIDAS OU SEMI-SóLIDAS, FORMULAçõES RETARDO PARA ADMINISTRAçãO PARENTERAL E PROCESSO DE PREPARO''<D>. A invenção tem por objeto a utilização, para o implante ou inserção, de uma formulação sólida (1), ou semi-sólida (18), destinada a ser colocada em um local de depósito preciso (T) de um organismo, contendo pelo menos um princípio ativo, essa formulação sendo de consistência sólida ou semi-sólida tal que possa persistir durante um certo período no local, e contendo uma dose de princípio ativo limitada para um tratamento em uma zona alvo do organismo, de um dispositivo que compreende uma parte colocada no interior do corpo do paciente com meios de acondicionamento da forma sólida ou semi-sólida, meios de posicionamento, permitindo levar esses meios de acondicionamento até o local de depósito, meios de injeção ou de inserção nesse local de depósito, e meios de retirada, após injeção ou inserção, e uma parte deixada no exterior com meios de ativação das funções do dispositivo. A invenção tem igualmente por objeto uma formulação retardo sólida para administração parenteral, compreendendo uma mistura homogênea de um princípio ativo no estado não dispersado e de um excipiente biocompatível biodegradável, na qual a quantidade de princípio ativo é de pelo menos 50% em peso.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9614755A FR2756493B1 (fr) | 1996-12-02 | 1996-12-02 | Dispositif d'administration locale de formulations solides ou semi-solides |
| PCT/FR1997/002182 WO1998024504A2 (fr) | 1996-12-02 | 1997-12-02 | Dispositif d'administration locale de formulations pharmaceutiques solides ou semi-solides, formulations pharmaceutiques retard pour l'administration parenterale et procede de preparation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR9713675A true BR9713675A (pt) | 2000-03-28 |
Family
ID=9498235
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR9713675-1A BR9713675A (pt) | 1996-12-02 | 1997-12-02 | Dispositivo de administração local de formulações sólidas ou semi - sólidas, formulações retardo para administração parenteral e processo de preparo |
Country Status (21)
| Country | Link |
|---|---|
| EP (2) | EP1159957A3 (pt) |
| JP (2) | JP2001506144A (pt) |
| KR (1) | KR100483447B1 (pt) |
| CN (2) | CN1210080C (pt) |
| AT (1) | ATE370764T1 (pt) |
| AU (1) | AU742061B2 (pt) |
| BR (1) | BR9713675A (pt) |
| CA (1) | CA2273017C (pt) |
| CZ (1) | CZ301103B6 (pt) |
| DE (1) | DE69738048T2 (pt) |
| DK (1) | DK0952867T3 (pt) |
| ES (1) | ES2290971T3 (pt) |
| FR (1) | FR2756493B1 (pt) |
| HU (1) | HU228236B1 (pt) |
| IL (1) | IL130211A (pt) |
| NO (1) | NO332358B1 (pt) |
| NZ (1) | NZ336074A (pt) |
| PL (1) | PL194894B1 (pt) |
| PT (1) | PT952867E (pt) |
| RU (1) | RU2207845C2 (pt) |
| WO (1) | WO1998024504A2 (pt) |
Families Citing this family (60)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2779340B1 (fr) | 1998-06-04 | 2000-12-29 | Delab | Dispositif intraluminal implantable |
| DE19961197B4 (de) * | 1999-12-18 | 2007-02-08 | Gaplast Gmbh | Implantatspritze |
| US6428559B1 (en) * | 2001-04-03 | 2002-08-06 | Cordis Corporation | Removable, variable-diameter vascular filter system |
| ATE353596T1 (de) * | 2001-07-12 | 2007-03-15 | Bavarian Nordic As | Injektionsvorrichtung zum injizieren von kapseln |
| GB0122113D0 (en) * | 2001-09-11 | 2001-10-31 | Astrazeneca Ab | Composition |
| JP2006520786A (ja) | 2003-03-14 | 2006-09-14 | シネクサス, インコーポレイテッド | 徐放性治療剤の洞送達 |
| BRPI0407818A (pt) * | 2003-03-14 | 2006-02-14 | Debio Rech Pharma Sa | sistema de distribuição subcutánea, processo para a preparação do mesmo e uso do mesmo para o tratamento das doenças da deficiência colinérgica |
| FR2865938B1 (fr) * | 2004-02-05 | 2006-06-02 | Sod Conseils Rech Applic | Formulation retard solide comprenant de l'acetate de triptoreline |
| SE0401182D0 (sv) * | 2004-05-05 | 2004-05-05 | Q Med Ab | Novel use of a viscoelastic composition |
| AU2004100402B4 (en) * | 2004-05-28 | 2005-04-07 | Stephen Paul Holdings Pty Ltd | Integrated water supply system for multi-floor buildings |
| EP2295036A2 (en) | 2004-12-10 | 2011-03-16 | Talima Therapeutics, Inc. | Liquid compositions and methods for treating conditions of the nail unit |
| US20060275230A1 (en) | 2004-12-10 | 2006-12-07 | Frank Kochinke | Compositions and methods for treating conditions of the nail unit |
| US7442187B2 (en) * | 2005-01-27 | 2008-10-28 | Boston Scientific Scimed, Inc. | Multiple needle injection catheter |
| CA2603081C (en) | 2005-04-04 | 2013-09-03 | Sinexus, Inc. | Device and methods for treating paranasal sinus conditions |
| US20070060887A1 (en) * | 2005-08-22 | 2007-03-15 | Marsh David A | Ophthalmic injector |
| US20070173706A1 (en) * | 2005-11-11 | 2007-07-26 | Isense Corporation | Method and apparatus for insertion of a sensor |
| US20070270744A1 (en) | 2006-05-17 | 2007-11-22 | Bruno Dacquay | Limited Reuse Assembly For Ophthalmic Injection Device |
| US7887521B2 (en) | 2006-05-17 | 2011-02-15 | Alcon Research, Ltd. | Ophthalmic injection system |
| US7811252B2 (en) | 2006-05-17 | 2010-10-12 | Alcon Research, Ltd. | Dosage control device |
| US8535707B2 (en) | 2006-07-10 | 2013-09-17 | Intersect Ent, Inc. | Devices and methods for delivering active agents to the osteomeatal complex |
| US9022970B2 (en) | 2006-10-16 | 2015-05-05 | Alcon Research, Ltd. | Ophthalmic injection device including dosage control device |
| US20080281292A1 (en) | 2006-10-16 | 2008-11-13 | Hickingbotham Dyson W | Retractable Injection Port |
| RU2317065C1 (ru) * | 2006-12-05 | 2008-02-20 | Владимир Андрианович Алешкин | Способ определения целевой доставки в желудочно-кишечном тракте твердой лекарственной формы с защитным покрытием |
| SE0701811L (sv) | 2007-08-02 | 2008-08-26 | Novoaim Ab | Kirurgiskt kit för fettransplantation |
| EP2200684B1 (en) * | 2007-08-17 | 2016-10-05 | Medtronic MiniMed, Inc. | Injection apparatus for making an injection at a predetermined depth in the skin |
| PT2231065T (pt) | 2007-12-18 | 2020-12-07 | Intersect Ent Inc | Dispositivos autoexpansíveis |
| AU2009276505B2 (en) | 2008-08-01 | 2015-04-23 | Intersect Ent, Inc. | Methods and devices for crimping self-expanding devices |
| EP3138603A1 (en) * | 2009-03-20 | 2017-03-08 | Incube Labs, Llc | Solid drug delivery apparatus, formulations and methods of use |
| US20100239632A1 (en) * | 2009-03-23 | 2010-09-23 | Warsaw Orthopedic, Inc. | Drug depots for treatment of pain and inflammation in sinus and nasal cavities or cardiac tissue |
| CA2759807C (en) * | 2009-04-23 | 2018-03-20 | Sustained Nano Systems Llc | Controlled release dispensing device |
| US8372036B2 (en) | 2009-05-06 | 2013-02-12 | Alcon Research, Ltd. | Multi-layer heat assembly for a drug delivery device |
| AU2010248992B2 (en) | 2009-05-15 | 2014-11-27 | Intersect Ent, Inc. | Expandable devices and methods therefor |
| US20110092918A1 (en) * | 2009-10-19 | 2011-04-21 | Ferrosan A/S | Malleable tip for applying an agent to a target site |
| US8177747B2 (en) | 2009-12-22 | 2012-05-15 | Alcon Research, Ltd. | Method and apparatus for drug delivery |
| CN101884570A (zh) * | 2010-08-04 | 2010-11-17 | 苏州欧莱美生物工程科技有限公司 | 一种针头刺入引导装置 |
| JP5696279B2 (ja) * | 2010-12-01 | 2015-04-08 | 学校法人自治医科大学 | 長期徐放型薬剤硬膜外腔留置システム |
| DE102011116973A1 (de) | 2011-10-26 | 2013-05-02 | Amw Gmbh | Implanter |
| JP2013172803A (ja) * | 2012-02-24 | 2013-09-05 | Masanori Saeki | 製剤注入具 |
| EP2968877B1 (en) | 2013-03-14 | 2020-01-01 | Intersect ENT, Inc. | Systems and devices for treating a sinus condition |
| CA2904703A1 (en) | 2013-03-14 | 2014-10-02 | Hallux, Inc. | Method of treating infections, diseases or disorders of nail unit |
| ITMI20131992A1 (it) * | 2013-11-28 | 2015-05-29 | Valerio Cigaina | Assieme comprendente un dispositivo per elettroneuromodulazione totalmente impiantabile ed uno strumento di impiantazione di detto dispositivo |
| WO2016198351A1 (en) * | 2015-06-10 | 2016-12-15 | Evonik Röhm Gmbh | Process for preparing a powder comprising a human coagulation factor protein and a lactic acid polymer |
| US10596330B2 (en) * | 2015-08-26 | 2020-03-24 | Medtronic Xomed, Inc. | Resorbable, drug-eluting submucosal turbinate implant device and method |
| AU2018300080B2 (en) | 2017-07-11 | 2024-09-19 | Sustained Nano Systems Llc | Hypercompressed pharmaceutical formulations |
| CA3069155A1 (en) * | 2017-07-11 | 2019-01-17 | Sustained Nano Systems Llc | Radiation sterilization of hypercompressed polymer dosage forms |
| DE102017007893A1 (de) * | 2017-08-19 | 2019-02-21 | Gaplast Gmbh | Implantatspritze |
| CN108187216B (zh) * | 2017-12-29 | 2021-03-16 | 耿海涛 | 一种肿瘤部位给药装置 |
| JP7394770B2 (ja) | 2018-02-09 | 2023-12-08 | アイコン バイオサイエンス,インコーポレイテッド | 注射器から少量の用量を装填および送達するためのシステム、キット、および方法 |
| WO2020021878A1 (ja) * | 2018-07-26 | 2020-01-30 | 株式会社カネカ | 生体内留置物およびその留置システム |
| EP3833631A4 (en) * | 2018-08-10 | 2022-04-20 | Azura Ophthalmics Ltd | DISPENSER FOR ACCURATE EXTRACTION OF A SEMI-SOLID PRODUCT |
| US11464914B2 (en) | 2019-10-21 | 2022-10-11 | Ripple Therapeutics Corporation | Intravitreal injector |
| CA3166357A1 (en) | 2020-01-10 | 2021-07-15 | Azura Ophthalmics Ltd. | Instructions for composition and sensitivity |
| CN112156170B (zh) * | 2020-11-03 | 2022-10-21 | 北京康欣东弘医药科技有限公司 | 可供皮下注射的曲普瑞林缓释微球及其制备方法和用途 |
| EP4477215A3 (en) | 2020-12-08 | 2025-02-19 | Ruminant Biotech Corp Limited | Improvements to devices and methods for delivery of substances to animals |
| CN112451850B (zh) * | 2020-12-11 | 2023-05-09 | 王姗姗 | 一种碘-125粒子用植入装置 |
| CN112472207B (zh) * | 2020-12-14 | 2021-11-05 | 中南大学湘雅医院 | 一种神经外科用临床介入治疗装置 |
| CN112970670B (zh) * | 2021-02-06 | 2022-08-05 | 澎立生物医药技术(上海)股份有限公司 | 一种肠粘膜炎动物模型的构建方法 |
| JP7562090B1 (ja) * | 2023-10-19 | 2024-10-07 | 国立大学法人高知大学 | マーカー、マーカー留置具及びマーカー検出装置 |
| CN117771475B (zh) * | 2024-02-27 | 2024-05-10 | 山东永聚医药科技股份有限公司 | 固体制剂用植入式预灌封注射器及其制备方法 |
| CN117942456B (zh) * | 2024-03-27 | 2024-07-12 | 山东永聚医药科技股份有限公司 | 缓释型非牛顿流体制剂用预灌封注射器及其制备工艺 |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE522404C (de) * | 1929-01-09 | 1931-04-08 | Hans E Hellwig | Instrument zur Einfuehrung von Radiumnadeln |
| US3545439A (en) | 1968-01-04 | 1970-12-08 | Upjohn Co | Medicated devices and methods |
| GB2091554B (en) * | 1981-01-13 | 1984-09-12 | Mitsui Toatsu Chemicals | Rod like moulded drug |
| EP0113713A1 (en) * | 1982-07-08 | 1984-07-25 | HARMAN, Mitchell | Injectible sustained release dosage cylinders |
| CA1196864A (en) * | 1983-06-10 | 1985-11-19 | Mattheus F.A. Goosen | Controlled release of injectable and implantable insulin compositions |
| JPS6036410A (ja) * | 1983-08-08 | 1985-02-25 | Unitika Ltd | 生分解性薬物供与体の製造方法 |
| AU571922B2 (en) * | 1984-01-26 | 1988-04-28 | Schering Agrochemicals Limited | Veterinary implants comprising melatonin and derivatives thereof |
| US4758435A (en) * | 1986-08-11 | 1988-07-19 | American Cyanamid Company | Estradiol implant composition and method for preparation |
| US4863736A (en) * | 1987-03-16 | 1989-09-05 | Monsanto Company | Somatotropin prolonged release |
| DK530787D0 (da) | 1987-10-09 | 1987-10-09 | Bukh Meditec | Indretning til indfoering i en legemshulhed |
| US5088935A (en) | 1991-04-05 | 1992-02-18 | Penn Engineering & Manufacturing Corp. | Electrical connector panel |
| US5219358A (en) * | 1991-08-29 | 1993-06-15 | Ethicon, Inc. | Shape memory effect surgical needles |
| DE69224386T2 (de) * | 1992-11-06 | 1998-06-18 | Texas Instruments Inc | Vorrichtung zum subkutanen Einführen einer Nadel |
| DK42093D0 (da) * | 1993-04-07 | 1993-04-07 | Bukh Meditec | Administrationsmetode |
| ATE195078T1 (de) * | 1994-04-27 | 2000-08-15 | Daiken Iki Co Ltd | Vorrichtung zum injizieren von flüssigkeiten |
| US5573542A (en) * | 1994-08-17 | 1996-11-12 | Tahoe Surgical Instruments-Puerto Rico | Endoscopic suture placement tool |
| US5582591A (en) | 1994-09-02 | 1996-12-10 | Delab | Delivery of solid drug compositions |
| US5542920A (en) * | 1994-09-12 | 1996-08-06 | Delab | Needle-less parenteral introduction device |
-
1996
- 1996-12-02 FR FR9614755A patent/FR2756493B1/fr not_active Expired - Fee Related
-
1997
- 1997-12-02 KR KR10-1999-7004879A patent/KR100483447B1/ko not_active Expired - Fee Related
- 1997-12-02 RU RU99113827/14A patent/RU2207845C2/ru not_active IP Right Cessation
- 1997-12-02 HU HU9904601A patent/HU228236B1/hu not_active IP Right Cessation
- 1997-12-02 AT AT97948983T patent/ATE370764T1/de active
- 1997-12-02 CN CNB971813035A patent/CN1210080C/zh not_active Expired - Fee Related
- 1997-12-02 EP EP01118964A patent/EP1159957A3/fr not_active Withdrawn
- 1997-12-02 EP EP97948983A patent/EP0952867B1/fr not_active Expired - Lifetime
- 1997-12-02 CA CA002273017A patent/CA2273017C/fr not_active Expired - Fee Related
- 1997-12-02 DE DE69738048T patent/DE69738048T2/de not_active Expired - Lifetime
- 1997-12-02 PL PL360774A patent/PL194894B1/pl unknown
- 1997-12-02 WO PCT/FR1997/002182 patent/WO1998024504A2/fr not_active Ceased
- 1997-12-02 AU AU76232/98A patent/AU742061B2/en not_active Ceased
- 1997-12-02 ES ES97948983T patent/ES2290971T3/es not_active Expired - Lifetime
- 1997-12-02 IL IL130211A patent/IL130211A/en not_active IP Right Cessation
- 1997-12-02 DK DK97948983T patent/DK0952867T3/da active
- 1997-12-02 PT PT97948983T patent/PT952867E/pt unknown
- 1997-12-02 CN CNA200510074284XA patent/CN1698580A/zh active Pending
- 1997-12-02 NZ NZ336074A patent/NZ336074A/en not_active IP Right Cessation
- 1997-12-02 CZ CZ0191999A patent/CZ301103B6/cs not_active IP Right Cessation
- 1997-12-02 BR BR9713675-1A patent/BR9713675A/pt not_active IP Right Cessation
- 1997-12-02 JP JP52527798A patent/JP2001506144A/ja active Pending
-
1999
- 1999-05-31 NO NO19992610A patent/NO332358B1/no not_active IP Right Cessation
-
2008
- 2008-10-15 JP JP2008266758A patent/JP5138537B2/ja not_active Expired - Fee Related
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