BR9713675A - Dispositivo de administração local de formulações sólidas ou semi - sólidas, formulações retardo para administração parenteral e processo de preparo - Google Patents
Dispositivo de administração local de formulações sólidas ou semi - sólidas, formulações retardo para administração parenteral e processo de preparoInfo
- Publication number
- BR9713675A BR9713675A BR9713675-1A BR9713675A BR9713675A BR 9713675 A BR9713675 A BR 9713675A BR 9713675 A BR9713675 A BR 9713675A BR 9713675 A BR9713675 A BR 9713675A
- Authority
- BR
- Brazil
- Prior art keywords
- solid
- semi
- formulations
- active ingredient
- administration
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61D—VETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
- A61D7/00—Devices or methods for introducing solid, liquid or gaseous remedies or other materials into or onto the bodies of animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0069—Devices for implanting pellets, e.g. markers or solid medicaments
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Dermatology (AREA)
- Biomedical Technology (AREA)
- Medical Informatics (AREA)
- Medicinal Chemistry (AREA)
- Anesthesiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Organic Chemistry (AREA)
- Pain & Pain Management (AREA)
- Wood Science & Technology (AREA)
- Neurosurgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Rheumatology (AREA)
- Zoology (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- Surgical Instruments (AREA)
- Endoscopes (AREA)
- Media Introduction/Drainage Providing Device (AREA)
Abstract
Patente de Invenção: <B>"DISPOSITIVO DE ADMINISTRAçãO LOCAL DE FORMULAçõES SóLIDAS OU SEMI-SóLIDAS, FORMULAçõES RETARDO PARA ADMINISTRAçãO PARENTERAL E PROCESSO DE PREPARO''<D>. A invenção tem por objeto a utilização, para o implante ou inserção, de uma formulação sólida (1), ou semi-sólida (18), destinada a ser colocada em um local de depósito preciso (T) de um organismo, contendo pelo menos um princípio ativo, essa formulação sendo de consistência sólida ou semi-sólida tal que possa persistir durante um certo período no local, e contendo uma dose de princípio ativo limitada para um tratamento em uma zona alvo do organismo, de um dispositivo que compreende uma parte colocada no interior do corpo do paciente com meios de acondicionamento da forma sólida ou semi-sólida, meios de posicionamento, permitindo levar esses meios de acondicionamento até o local de depósito, meios de injeção ou de inserção nesse local de depósito, e meios de retirada, após injeção ou inserção, e uma parte deixada no exterior com meios de ativação das funções do dispositivo. A invenção tem igualmente por objeto uma formulação retardo sólida para administração parenteral, compreendendo uma mistura homogênea de um princípio ativo no estado não dispersado e de um excipiente biocompatível biodegradável, na qual a quantidade de princípio ativo é de pelo menos 50% em peso.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9614755A FR2756493B1 (fr) | 1996-12-02 | 1996-12-02 | Dispositif d'administration locale de formulations solides ou semi-solides |
| PCT/FR1997/002182 WO1998024504A2 (fr) | 1996-12-02 | 1997-12-02 | Dispositif d'administration locale de formulations pharmaceutiques solides ou semi-solides, formulations pharmaceutiques retard pour l'administration parenterale et procede de preparation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR9713675A true BR9713675A (pt) | 2000-03-28 |
Family
ID=9498235
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR9713675-1A BR9713675A (pt) | 1996-12-02 | 1997-12-02 | Dispositivo de administração local de formulações sólidas ou semi - sólidas, formulações retardo para administração parenteral e processo de preparo |
Country Status (21)
| Country | Link |
|---|---|
| EP (2) | EP1159957A3 (pt) |
| JP (2) | JP2001506144A (pt) |
| KR (1) | KR100483447B1 (pt) |
| CN (2) | CN1698580A (pt) |
| AT (1) | ATE370764T1 (pt) |
| AU (1) | AU742061B2 (pt) |
| BR (1) | BR9713675A (pt) |
| CA (1) | CA2273017C (pt) |
| CZ (1) | CZ301103B6 (pt) |
| DE (1) | DE69738048T2 (pt) |
| DK (1) | DK0952867T3 (pt) |
| ES (1) | ES2290971T3 (pt) |
| FR (1) | FR2756493B1 (pt) |
| HU (1) | HU228236B1 (pt) |
| IL (1) | IL130211A (pt) |
| NO (1) | NO332358B1 (pt) |
| NZ (1) | NZ336074A (pt) |
| PL (1) | PL194894B1 (pt) |
| PT (1) | PT952867E (pt) |
| RU (1) | RU2207845C2 (pt) |
| WO (1) | WO1998024504A2 (pt) |
Families Citing this family (62)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2779340B1 (fr) | 1998-06-04 | 2000-12-29 | Delab | Dispositif intraluminal implantable |
| DE19961197B4 (de) * | 1999-12-18 | 2007-02-08 | Gaplast Gmbh | Implantatspritze |
| US6428559B1 (en) * | 2001-04-03 | 2002-08-06 | Cordis Corporation | Removable, variable-diameter vascular filter system |
| DE50209493D1 (de) * | 2001-07-12 | 2007-03-29 | Bavarian Nordic As | Injektionsvorrichtung zum injizieren von kapseln |
| GB0122113D0 (en) * | 2001-09-11 | 2001-10-31 | Astrazeneca Ab | Composition |
| ES2312981T3 (es) * | 2003-03-14 | 2009-03-01 | Debio Recherche Pharmaceutique S.A. | Sistema de suministro subcutaneo, procedimiento para la preparacion del mismo y utilizacion del mismo para el tratamiento de trastornos de deficiencia colinergica. |
| AU2004222340B2 (en) | 2003-03-14 | 2009-11-12 | Intersect Ent, Inc. | Sinus delivery of sustained release therapeutics |
| FR2865938B1 (fr) * | 2004-02-05 | 2006-06-02 | Sod Conseils Rech Applic | Formulation retard solide comprenant de l'acetate de triptoreline |
| SE0401182D0 (sv) | 2004-05-05 | 2004-05-05 | Q Med Ab | Novel use of a viscoelastic composition |
| AU2004100402B4 (en) * | 2004-05-28 | 2005-04-07 | Stephen Paul Holdings Pty Ltd | Integrated water supply system for multi-floor buildings |
| US20060275230A1 (en) | 2004-12-10 | 2006-12-07 | Frank Kochinke | Compositions and methods for treating conditions of the nail unit |
| MX2007006833A (es) | 2004-12-10 | 2007-10-08 | Talima Therapeutics Inc | Composiciones y metodos para tratar condiciones de la unidad de una. |
| US7442187B2 (en) * | 2005-01-27 | 2008-10-28 | Boston Scientific Scimed, Inc. | Multiple needle injection catheter |
| AU2006231506B2 (en) | 2005-04-04 | 2012-08-30 | Intersect Ent, Inc. | Device and methods for treating paranasal sinus conditions |
| US20070060887A1 (en) * | 2005-08-22 | 2007-03-15 | Marsh David A | Ophthalmic injector |
| US20070173706A1 (en) * | 2005-11-11 | 2007-07-26 | Isense Corporation | Method and apparatus for insertion of a sensor |
| US7815603B2 (en) | 2006-05-17 | 2010-10-19 | Alcon Research, Ltd. | Ophthalmic injection method |
| US7811252B2 (en) | 2006-05-17 | 2010-10-12 | Alcon Research, Ltd. | Dosage control device |
| US7887521B2 (en) | 2006-05-17 | 2011-02-15 | Alcon Research, Ltd. | Ophthalmic injection system |
| US8535707B2 (en) | 2006-07-10 | 2013-09-17 | Intersect Ent, Inc. | Devices and methods for delivering active agents to the osteomeatal complex |
| US9022970B2 (en) | 2006-10-16 | 2015-05-05 | Alcon Research, Ltd. | Ophthalmic injection device including dosage control device |
| US20080281292A1 (en) | 2006-10-16 | 2008-11-13 | Hickingbotham Dyson W | Retractable Injection Port |
| RU2317065C1 (ru) * | 2006-12-05 | 2008-02-20 | Владимир Андрианович Алешкин | Способ определения целевой доставки в желудочно-кишечном тракте твердой лекарственной формы с защитным покрытием |
| SE530729C2 (sv) | 2007-08-02 | 2008-08-26 | Novoaim Ab | Kirurgiskt kit för fettransplantation |
| EP2200684B1 (en) * | 2007-08-17 | 2016-10-05 | Medtronic MiniMed, Inc. | Injection apparatus for making an injection at a predetermined depth in the skin |
| EP2231065B8 (en) | 2007-12-18 | 2021-01-06 | Intersect ENT, Inc. | Self-expanding devices |
| CA2732355A1 (en) | 2008-08-01 | 2010-02-04 | Intersect Ent, Inc. | Methods and devices for crimping self-expanding devices |
| CN105688327A (zh) * | 2009-03-20 | 2016-06-22 | 因卡伯实验室有限责任公司 | 固体形式的药品 |
| US20100239632A1 (en) * | 2009-03-23 | 2010-09-23 | Warsaw Orthopedic, Inc. | Drug depots for treatment of pain and inflammation in sinus and nasal cavities or cardiac tissue |
| WO2010123563A2 (en) * | 2009-04-23 | 2010-10-28 | Sustained Nano Systems Llc | Controlled release dispensing device |
| US8372036B2 (en) | 2009-05-06 | 2013-02-12 | Alcon Research, Ltd. | Multi-layer heat assembly for a drug delivery device |
| CN106039547A (zh) | 2009-05-15 | 2016-10-26 | 因特尔赛克特耳鼻喉公司 | 可展开装置及其使用方法 |
| US20110092918A1 (en) * | 2009-10-19 | 2011-04-21 | Ferrosan A/S | Malleable tip for applying an agent to a target site |
| US8177747B2 (en) | 2009-12-22 | 2012-05-15 | Alcon Research, Ltd. | Method and apparatus for drug delivery |
| CN101884570A (zh) * | 2010-08-04 | 2010-11-17 | 苏州欧莱美生物工程科技有限公司 | 一种针头刺入引导装置 |
| JP5696279B2 (ja) * | 2010-12-01 | 2015-04-08 | 学校法人自治医科大学 | 長期徐放型薬剤硬膜外腔留置システム |
| DE102011116973A1 (de) | 2011-10-26 | 2013-05-02 | Amw Gmbh | Implanter |
| JP2013172803A (ja) * | 2012-02-24 | 2013-09-05 | Masanori Saeki | 製剤注入具 |
| CN105377355A (zh) | 2013-03-14 | 2016-03-02 | 拇趾公司 | 治疗甲单元的感染、疾病或病症的方法 |
| EP2968877B1 (en) | 2013-03-14 | 2020-01-01 | Intersect ENT, Inc. | Systems and devices for treating a sinus condition |
| ITMI20131992A1 (it) * | 2013-11-28 | 2015-05-29 | Valerio Cigaina | Assieme comprendente un dispositivo per elettroneuromodulazione totalmente impiantabile ed uno strumento di impiantazione di detto dispositivo |
| WO2016198351A1 (en) * | 2015-06-10 | 2016-12-15 | Evonik Röhm Gmbh | Process for preparing a powder comprising a human coagulation factor protein and a lactic acid polymer |
| US10596330B2 (en) * | 2015-08-26 | 2020-03-24 | Medtronic Xomed, Inc. | Resorbable, drug-eluting submucosal turbinate implant device and method |
| MX2020000377A (es) * | 2017-07-11 | 2020-07-14 | Sustained Nano Systems Llc | Esterilizacion mediante radiacion de formas de dosis de polimero hipercomprimido. |
| BR112020000506A2 (pt) | 2017-07-11 | 2020-07-14 | Sustained Nano Systems Llc | formulações farmacêuticas hipercomprimidas |
| DE102017007893A1 (de) * | 2017-08-19 | 2019-02-21 | Gaplast Gmbh | Implantatspritze |
| CN108187216B (zh) * | 2017-12-29 | 2021-03-16 | 耿海涛 | 一种肿瘤部位给药装置 |
| EP3749386B1 (en) | 2018-02-09 | 2026-04-15 | Icon Bioscience, Inc. | Systems, kits and methods for loading and delivering a small volume dose from a syringe |
| JP7370981B2 (ja) * | 2018-07-26 | 2023-10-30 | 株式会社カネカ | 生体内留置物の製造方法および留置システム |
| EP3833631A4 (en) * | 2018-08-10 | 2022-04-20 | Azura Ophthalmics Ltd | DISPENSER FOR ACCURATE EXTRACTION OF A SEMI-SOLID PRODUCT |
| US11464914B2 (en) * | 2019-10-21 | 2022-10-11 | Ripple Therapeutics Corporation | Intravitreal injector |
| EP4087655A4 (en) | 2020-01-10 | 2024-02-21 | Azura Ophthalmics Ltd | INSTRUCTIONS FOR COMPOSITION AND SENSITIVITY |
| CN112156170B (zh) * | 2020-11-03 | 2022-10-21 | 北京康欣东弘医药科技有限公司 | 可供皮下注射的曲普瑞林缓释微球及其制备方法和用途 |
| US11529310B2 (en) | 2020-12-08 | 2022-12-20 | Ruminant Biotech Corp Limited | Devices and methods for delivery of substances to animals |
| CN112451850B (zh) * | 2020-12-11 | 2023-05-09 | 王姗姗 | 一种碘-125粒子用植入装置 |
| CN112472207B (zh) * | 2020-12-14 | 2021-11-05 | 中南大学湘雅医院 | 一种神经外科用临床介入治疗装置 |
| CN112970670B (zh) * | 2021-02-06 | 2022-08-05 | 澎立生物医药技术(上海)股份有限公司 | 一种肠粘膜炎动物模型的构建方法 |
| CA3235477A1 (en) * | 2021-10-17 | 2023-04-20 | Trigone Pharma Ltd. | Compositions and methods for drug instillation into the urinary bladder |
| KR102955212B1 (ko) * | 2021-11-19 | 2026-04-21 | 허윤정 | 종양 내 약물 균일 주입 장치 |
| JP7562090B1 (ja) * | 2023-10-19 | 2024-10-07 | 国立大学法人高知大学 | マーカー、マーカー留置具及びマーカー検出装置 |
| CN117771475B (zh) * | 2024-02-27 | 2024-05-10 | 山东永聚医药科技股份有限公司 | 固体制剂用植入式预灌封注射器及其制备方法 |
| CN117942456B (zh) * | 2024-03-27 | 2024-07-12 | 山东永聚医药科技股份有限公司 | 缓释型非牛顿流体制剂用预灌封注射器及其制备工艺 |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE522404C (de) * | 1929-01-09 | 1931-04-08 | Hans E Hellwig | Instrument zur Einfuehrung von Radiumnadeln |
| US3545439A (en) | 1968-01-04 | 1970-12-08 | Upjohn Co | Medicated devices and methods |
| GB2091554B (en) * | 1981-01-13 | 1984-09-12 | Mitsui Toatsu Chemicals | Rod like moulded drug |
| WO1984000304A1 (en) * | 1982-07-08 | 1984-02-02 | Mitchell Harman | Injectible sustained release dosage cylinders |
| CA1196864A (en) * | 1983-06-10 | 1985-11-19 | Mattheus F.A. Goosen | Controlled release of injectable and implantable insulin compositions |
| JPS6036410A (ja) * | 1983-08-08 | 1985-02-25 | Unitika Ltd | 生分解性薬物供与体の製造方法 |
| AU571922B2 (en) * | 1984-01-26 | 1988-04-28 | Schering Agrochemicals Limited | Veterinary implants comprising melatonin and derivatives thereof |
| US4758435A (en) * | 1986-08-11 | 1988-07-19 | American Cyanamid Company | Estradiol implant composition and method for preparation |
| US4863736A (en) * | 1987-03-16 | 1989-09-05 | Monsanto Company | Somatotropin prolonged release |
| DK530787D0 (da) | 1987-10-09 | 1987-10-09 | Bukh Meditec | Indretning til indfoering i en legemshulhed |
| US5088935A (en) | 1991-04-05 | 1992-02-18 | Penn Engineering & Manufacturing Corp. | Electrical connector panel |
| US5219358A (en) * | 1991-08-29 | 1993-06-15 | Ethicon, Inc. | Shape memory effect surgical needles |
| EP0596161B1 (en) * | 1992-11-06 | 1998-02-04 | Texas Instruments Incorporated | Apparatus for subcutaneous introduction of a needle |
| DK42093D0 (da) * | 1993-04-07 | 1993-04-07 | Bukh Meditec | Administrationsmetode |
| EP0715861B1 (en) * | 1994-04-27 | 2000-08-02 | Daiken Iki Co. Ltd. | Liquid injection device |
| US5573542A (en) * | 1994-08-17 | 1996-11-12 | Tahoe Surgical Instruments-Puerto Rico | Endoscopic suture placement tool |
| US5582591A (en) | 1994-09-02 | 1996-12-10 | Delab | Delivery of solid drug compositions |
| US5542920A (en) * | 1994-09-12 | 1996-08-06 | Delab | Needle-less parenteral introduction device |
-
1996
- 1996-12-02 FR FR9614755A patent/FR2756493B1/fr not_active Expired - Fee Related
-
1997
- 1997-12-02 IL IL130211A patent/IL130211A/en not_active IP Right Cessation
- 1997-12-02 PT PT97948983T patent/PT952867E/pt unknown
- 1997-12-02 AT AT97948983T patent/ATE370764T1/de active
- 1997-12-02 BR BR9713675-1A patent/BR9713675A/pt not_active IP Right Cessation
- 1997-12-02 EP EP01118964A patent/EP1159957A3/fr not_active Withdrawn
- 1997-12-02 CN CNA200510074284XA patent/CN1698580A/zh active Pending
- 1997-12-02 CA CA002273017A patent/CA2273017C/fr not_active Expired - Fee Related
- 1997-12-02 AU AU76232/98A patent/AU742061B2/en not_active Ceased
- 1997-12-02 ES ES97948983T patent/ES2290971T3/es not_active Expired - Lifetime
- 1997-12-02 PL PL360774A patent/PL194894B1/pl unknown
- 1997-12-02 EP EP97948983A patent/EP0952867B1/fr not_active Expired - Lifetime
- 1997-12-02 HU HU9904601A patent/HU228236B1/hu not_active IP Right Cessation
- 1997-12-02 CZ CZ0191999A patent/CZ301103B6/cs not_active IP Right Cessation
- 1997-12-02 JP JP52527798A patent/JP2001506144A/ja active Pending
- 1997-12-02 NZ NZ336074A patent/NZ336074A/en not_active IP Right Cessation
- 1997-12-02 RU RU99113827/14A patent/RU2207845C2/ru not_active IP Right Cessation
- 1997-12-02 KR KR10-1999-7004879A patent/KR100483447B1/ko not_active Expired - Fee Related
- 1997-12-02 DK DK97948983T patent/DK0952867T3/da active
- 1997-12-02 WO PCT/FR1997/002182 patent/WO1998024504A2/fr not_active Ceased
- 1997-12-02 CN CNB971813035A patent/CN1210080C/zh not_active Expired - Fee Related
- 1997-12-02 DE DE69738048T patent/DE69738048T2/de not_active Expired - Lifetime
-
1999
- 1999-05-31 NO NO19992610A patent/NO332358B1/no not_active IP Right Cessation
-
2008
- 2008-10-15 JP JP2008266758A patent/JP5138537B2/ja not_active Expired - Fee Related
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US9186489B2 (en) | Implantable delivery device system for delivery of a medicament to a bladder | |
| WO1998024504A3 (fr) | Dispositif d'administration locale de formulations pharmaceutiques solides ou semi-solides, formulations pharmaceutiques retard pour l'administration parenterale et procede de preparation | |
| KR950700056A (ko) | 분무-냉각된 나부메톤(Spray-chilled nabumetone) | |
| BR0014928A (pt) | Dispositivo e processo para distribuição de medicamento para um olho humano | |
| BR0112356A (pt) | Formulações farmacêuticas tópicas e métodos de tratamento | |
| BRPI0820800B8 (pt) | dispositivo médico implantável para liberação controlada de droga | |
| BR9809453A (pt) | Composição de suprimento de medicamento para a liberação controlada de um ingrediente ativo dentro do meio-ambiente do estÈmago, uso da mesma, formulação farmacêutica, processo para obter gastrorretenção, para o tratamento ou profilaxia de uma doença, para melhorar a absorção gastrointestinal de medicamentos, e para a preparação de uma composição, e, estojo de partes para uso no tratamento de infecção por h. pylori. | |
| HU9502086D0 (en) | Reversible, thermally gelling water-base medicinal compositions | |
| BR9706802A (pt) | Anel vaginal, corpo de anel vaginal, conjunto, e, processos para administrar um medicamento a uma mulher e para preparar um anel vaginal. | |
| BR9808888A (pt) | Formas de dosagem e método de melhorar disfunção erétil masculina | |
| JP2001510795A5 (pt) | ||
| BR0010531A (pt) | Composições e usos de et743 para tratamento de câncer | |
| KR880007073A (ko) | 의 약 품 | |
| GROVES et al. | Contracture of the deltoid muscle in the adult after intramuscular injections: report of three cases | |
| IL272036B2 (en) | Methods and compositions for treating pain using capsaicin | |
| Rosin et al. | Cefazolin antibacterial activity and concentrations in serum and the surgical wound in dogs | |
| US4828828A (en) | Method of treating degenerative joint disease by injection of meth(acrylamide) (co)-polymers | |
| BR0314617A (pt) | Método para cardioproteção e neuroproteção por administração intravenosa de anestésico voláteis halogenados | |
| GR3017855T3 (en) | Use of lithium in the treatment or prophylaxis of Molluscum contagiosum. | |
| DE69426530D1 (de) | Pharmazeutische zusammensetzung zur förderung der gewebeheilung und -regenerierung und darreichungssatz | |
| PT1305057E (pt) | Composicao de biomateria microparticular para uso medicinal | |
| BR0008057A (pt) | Forma cristalina de eplerenona apresentando velocidade de dissolução intensificada | |
| BR0207866A (pt) | Uso de flumazenil na preparação de um medicamento para o tratamento da dependência de cocaìna | |
| BRPI0409387A (pt) | método para o tratamento de doença de tecido mole em um indivìduo mamìfero, composição farmacêutica, complexo de alvejamento de tecido mole, método para a formação de um complexo, e, kit para uso em um método | |
| Lewis et al. | The use of high-dose lidocaine in wetting solutions for lipoplasty |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PC | Transfer |
Free format text: SOCIETE DE CONSEILS DE RECHERCHES ET D APPLICATIONS SCIENTIFIQUES (S.C.R.A.S) (FR) |
|
| B06A | Patent application procedure suspended [chapter 6.1 patent gazette] | ||
| B09A | Decision: intention to grant [chapter 9.1 patent gazette] | ||
| B16A | Patent or certificate of addition of invention granted [chapter 16.1 patent gazette] | ||
| B21F | Lapse acc. art. 78, item iv - on non-payment of the annual fees in time |
Free format text: REFERENTE A 17A ANUIDADE. |
|
| B24J | Lapse because of non-payment of annual fees (definitively: art 78 iv lpi, resolution 113/2013 art. 12) |
Free format text: EM VIRTUDE DA EXTINCAO PUBLICADA NA RPI 2282 DE 30-09-2014 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDA A EXTINCAO DA PATENTE E SEUS CERTIFICADOS, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013. |