BR9811086A - Utilização de preparados de eritropoietina e ferro, processo para a produção de um preparado de combinação farmacêutica e embalagem unitária farmacêutica - Google Patents

Utilização de preparados de eritropoietina e ferro, processo para a produção de um preparado de combinação farmacêutica e embalagem unitária farmacêutica

Info

Publication number
BR9811086A
BR9811086A BR9811086-1A BR9811086A BR9811086A BR 9811086 A BR9811086 A BR 9811086A BR 9811086 A BR9811086 A BR 9811086A BR 9811086 A BR9811086 A BR 9811086A
Authority
BR
Brazil
Prior art keywords
pharmaceutical
production
erythropoietin
combination preparation
unit packaging
Prior art date
Application number
BR9811086-1A
Other languages
English (en)
Inventor
Paul Lehmann
Joachim Peter Kaltwasser
Original Assignee
Roche Diagnostics Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roche Diagnostics Gmbh filed Critical Roche Diagnostics Gmbh
Publication of BR9811086A publication Critical patent/BR9811086A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/1816—Erythropoietin [EPO]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

<B><MU>UTILIZAçãO DE PREPARADOS DE ERITROPOIETINA E FERRO, PROCESSO PARA A PRODUçãO DE UM PREPARADO DE COMBINAçãO FARMACêUTICA E EMBALAGEM UNITáRIA FARMACêUTICA<MV><D> A invenção refere-se à utilização de formas de administração únicas de um preparado de eritropoietina e de um preparado de ferro fisiologicamente adequado, correspondente a uma quantidade equivalente de 1-40 mg de íons de ferro, para produzir um preparado de combinação farmacêutica para o tratamento de doenças reumáticas.
BR9811086-1A 1997-08-08 1998-08-05 Utilização de preparados de eritropoietina e ferro, processo para a produção de um preparado de combinação farmacêutica e embalagem unitária farmacêutica BR9811086A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19734293A DE19734293A1 (de) 1997-08-08 1997-08-08 Verwendung von pharmazeutischen Kombinationspräparaten enthaltend Erythropoietin und Eisenpräparate zur Behandlung von rheumatischen Erkrankungen
PCT/EP1998/004864 WO1999007401A2 (de) 1997-08-08 1998-08-05 Verwendung von erythropoietin und eisenpräparaten zur herstellung von pharmazeutischen kombinationspräparaten zur behandlung von rheumatischen erkrankungen

Publications (1)

Publication Number Publication Date
BR9811086A true BR9811086A (pt) 2000-08-29

Family

ID=7838328

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9811086-1A BR9811086A (pt) 1997-08-08 1998-08-05 Utilização de preparados de eritropoietina e ferro, processo para a produção de um preparado de combinação farmacêutica e embalagem unitária farmacêutica

Country Status (15)

Country Link
US (1) US6372715B1 (pt)
EP (1) EP1037648B1 (pt)
JP (3) JP2001513510A (pt)
KR (1) KR100478573B1 (pt)
CN (1) CN1170589C (pt)
AT (1) ATE263571T1 (pt)
AU (1) AU738027B2 (pt)
BR (1) BR9811086A (pt)
CA (1) CA2297959C (pt)
DE (2) DE19734293A1 (pt)
DK (1) DK1037648T3 (pt)
ES (1) ES2218851T3 (pt)
PT (1) PT1037648E (pt)
TR (1) TR200000369T2 (pt)
WO (1) WO1999007401A2 (pt)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT977582E (pt) * 1997-03-18 2002-12-31 Roche Diagnostics Gmbh Preparacoes farmaceuticas associadas contendo eritropoietina e preparacoes de ferro
DE19734293A1 (de) * 1997-08-08 1999-02-11 Boehringer Mannheim Gmbh Verwendung von pharmazeutischen Kombinationspräparaten enthaltend Erythropoietin und Eisenpräparate zur Behandlung von rheumatischen Erkrankungen
PL219131B1 (pl) * 2000-05-15 2015-03-31 Hoffmann La Roche Ciekła kompozycja farmaceutyczna, sposób jej wytwarzania oraz jej zastosowanie
JP4369120B2 (ja) * 2000-11-02 2009-11-18 クロマシューティカル・アドヴァンスト・テクノロジーズ，インコーポレイテッド 精製された造血性鉄−サッカリド錯体の生成方法およびそれによって生成した生成物
US6929954B2 (en) 2000-11-02 2005-08-16 Chromaceutical Advanced Technologies, Inc. Method for producing purified hematinic iron-saccharidic complex and product produced
CA2431964C (en) 2000-12-20 2013-09-10 F. Hoffmann-La Roche Ag Conjugates of erythropoietin (pep) with polyethylene glycol (peg)
EP1909106B1 (en) 2001-09-14 2013-01-02 F. Hoffmann-La Roche AG Differential diagnosis of disorders of iron metabolism by means of four parameters and recommendations for the treatment of these disorders of iron metabolism
US7459435B2 (en) * 2002-08-29 2008-12-02 Hoffmann-La Roche Inc. Treatment of disturbances of iron distribution
US7459436B2 (en) * 2002-11-22 2008-12-02 Hoffmann-La Roche Inc. Treatment of disturbances of iron distribution
US7964568B2 (en) * 2003-05-30 2011-06-21 Chromaceutical Advanced Technologies, Inc. Synthesis of high molecular weight iron-saccharidic complexes
CA2597154C (en) * 2005-02-09 2011-03-15 Vifor (International) Ag Use of iron(iii) complex compounds
CN102961746B (zh) 2005-05-16 2016-06-15 艾伯维生物技术有限公司 TNFα抑制剂治疗腐蚀性多关节炎的用途
EP1790356A1 (de) * 2005-11-24 2007-05-30 Vifor (International) Ag Präparat, umfassend Eisen(III)-Komplexverbindungen und redoxaktive Substanz(en)
US9605064B2 (en) 2006-04-10 2017-03-28 Abbvie Biotechnology Ltd Methods and compositions for treatment of skin disorders
US9399061B2 (en) * 2006-04-10 2016-07-26 Abbvie Biotechnology Ltd Methods for determining efficacy of TNF-α inhibitors for treatment of rheumatoid arthritis
US20080131374A1 (en) * 2006-04-19 2008-06-05 Medich John R Uses and compositions for treatment of rheumatoid arthritis
PL2054074T3 (pl) 2006-08-04 2015-03-31 Prolong Pharmaceuticals Llc Zmodyfikowana erytropoetyna
US20080132465A1 (en) * 2006-12-05 2008-06-05 Vincent Windisch Apparatus and method for isolating iron components from serum
CL2008002054A1 (es) 2007-07-17 2009-05-29 Hoffmann La Roche Metodo para la regeneracion de una columna de cromatografia de intercambio cationico despues de la elusion de eritropoyetina monopeguilada y metodo para obtener una eritropoyetina monopeguilada, incorporando el metodo de regeneracion de la columna de intercambio cationico.
CL2008002053A1 (es) * 2007-07-17 2009-05-22 Hoffmann La Roche Metodo para la purificacion de una eritropoyetina monopeguilada (epompeg) que consiste en proporcionar una solucion que contiene eritropoyetina mono, poli y no peguilada y hacerla pasar por dos pasos de cromatografia de intercambio cationico y metodo para producir epo mpeg que incluye metodo de purificacion.
US20100040630A1 (en) * 2008-03-24 2010-02-18 Aake Elden Methods and compositions for treating bone loss
US8202830B2 (en) 2009-01-30 2012-06-19 Ecolab Usa Inc. Development of an aluminum hydroxydicarboxylate builder
AU2010209328B2 (en) * 2009-01-30 2015-07-02 Ecolab Inc. Development of an aluminum hydroxycarboxylate builder
US8536106B2 (en) 2010-04-14 2013-09-17 Ecolab Usa Inc. Ferric hydroxycarboxylate as a builder
JP6085401B2 (ja) * 2014-07-25 2017-02-22 原　和弘 薬剤投与情報提供装置及び薬剤投与情報提供のためのコンピュータプログラム
PT3380487T (pt) 2015-11-23 2020-10-29 Bristol Myers Squibb Co Sistemas de aditivos para utilização na peguilação de proteínas

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ194947A (en) * 1979-09-18 1983-06-14 C Holland Composition containing calcium and ferrous ions for treatment of rheumatoid arthritis
US4732889A (en) * 1985-02-06 1988-03-22 Chugai Seiyaku Kabushiki Kaisha Pharmaceutical composition for the treatment of the anemia of rheumatoid arthritis
EP0784480B1 (en) * 1994-11-03 2003-10-15 Boehringer Mannheim Gmbh Use of erythropoietin in the treatment of rheumatoid arthritis
DE19535571A1 (de) * 1995-09-14 1997-03-20 Boehringer Mannheim Gmbh Pharmazeutische Kombinationspräparate und deren Verwendung zur Behandlung von Hämodialysepatienten
DE19734293A1 (de) * 1997-08-08 1999-02-11 Boehringer Mannheim Gmbh Verwendung von pharmazeutischen Kombinationspräparaten enthaltend Erythropoietin und Eisenpräparate zur Behandlung von rheumatischen Erkrankungen

Also Published As

Publication number Publication date
EP1037648B1 (de) 2004-04-07
KR100478573B1 (ko) 2005-03-28
JP2008133290A (ja) 2008-06-12
DK1037648T3 (da) 2004-08-02
CN1268058A (zh) 2000-09-27
CA2297959C (en) 2011-11-29
ES2218851T3 (es) 2004-11-16
KR20010022738A (ko) 2001-03-26
JP2001513510A (ja) 2001-09-04
US6372715B1 (en) 2002-04-16
WO1999007401A2 (de) 1999-02-18
ATE263571T1 (de) 2004-04-15
CN1170589C (zh) 2004-10-13
PT1037648E (pt) 2004-08-31
JP2012012410A (ja) 2012-01-19
TR200000369T2 (tr) 2000-09-21
CA2297959A1 (en) 1999-02-18
WO1999007401A3 (de) 1999-04-29
DE19734293A1 (de) 1999-02-11
AU738027B2 (en) 2001-09-06
DE59811158D1 (de) 2004-05-13
EP1037648A2 (de) 2000-09-27
AU9159098A (en) 1999-03-01

Similar Documents

Publication Publication Date Title
BR9811086A (pt) Utilização de preparados de eritropoietina e ferro, processo para a produção de um preparado de combinação farmacêutica e embalagem unitária farmacêutica
SE9703191D0 (sv) Medicament for improvement of duration of muscle function or treatment of muscle disorders or diseases
BR0112591A (pt) Derivados de acridina e sua aplicação como medicamento
AR032293A1 (es) Estuche farmaceutico
BG106095A (bg) Нови лекарствени състави на базата на антихолинергично активни съединения и бета-миметици
BR9712523A (pt) Novos derivados de pirazol heterociclilmetil-substituìdos
CY1107838T1 (el) Παραγωγα αδαμαντανιου για τη θεραπεια φλεγμονωδων, ανοσολογικων και καρδιαγγειακων ασθενειων
DE60115029D1 (de) Pharmazeutische zusammensetzungen enthaltend cannabidiol-derivate
EA200100524A1 (ru) Амиды антраниловой кислоты и их применение в качестве лекарственных средств
NZ516347A (en) Indanyl-substituted benzenecarboxamides, process for their preparation, their use as a medicament and pharmaceutical formulations containing them
BR0015188A (pt) Composições farmacêuticas
MXPA03010402A (es) Derivados de 4-amino-5-fenil-7-ciclobutil-pirrolo (2,3-d) pirimidina.
BR0209845A (pt) Formas de dosagem de oxcarbazepina e processo para a preparação das mesmas
IS7006A (is) Tvívetnis 3-piperidínóprópíófenon og lyf sem innihalda téð efnasambönd
NO20023551D0 (no) Ibuprofen-inneholdende aktivt middel-preparat
HUP9700806A2 (hu) Tianeptin-nátriumsó nyújtott felszabadulását biztosító, szájon át beadható mátrix tabletta és eljárás előállítására
ES2191449T3 (es) Derivados de ciclopentabenzofurano y su uso.
BR0112807A (pt) Derivados de indol e sua aplicação como medicamento
SE8901003D0 (sv) Snabbloesliga preparat
BR0116653A (pt) Medicamento contendo uma poliamina como substância ativa
WO2001041747A3 (de) Pharmazeutische zubeteitung enthaltend zytostatika und electronenakzeptoren zur behandlung von krebs
HUP9902135A2 (hu) (+)-alfa-(2,3-Dimetoxi-fenil)-1-[2-(4-fluor-fenil)-etil]-4-piperidin-metanol alkalmazása depresszív és bipoláris rendellenességek kezelésére alkalmas gyógyszerkészítmény előállítására
BG105326A (bg) Нови бензоилгуанидинови производни с преимуществени свойства, метод за тяхното получаване и тяхнотоприложение при производството на лекарствени средства
BR9710629A (pt) Composi-Æo farmac-utica processo para sua prepara-Æo composto para utiliza-Æo como agente terap-utico e utiliza-Æo e utiliza-Æo de um composto
EA200400691A1 (ru) Получение чистых стереоизомеров трицикло[5,2,1,02,6]дец-9-ил-ксантогената и содержащие их лекарственные средства

Legal Events

Date Code Title Description
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: DE ACORDO COM O ART. 36 DA LPI (LEI 9279/96) 2O, O PEDIDO VOLTA A EXAME SENDO CONSIDERADO NAO PATENTEAVEL PELAS RAZOES EXPOSTAS NO PARECER TECNICO ANTERIOR.