DK1037648T3 - Anvendelse af erythropoietin og jernpræparater til fremstilling af farmaceutiske kombinationspræparater til behandling af rheumatiske lidelser - Google Patents
Anvendelse af erythropoietin og jernpræparater til fremstilling af farmaceutiske kombinationspræparater til behandling af rheumatiske lidelserInfo
- Publication number
- DK1037648T3 DK1037648T3 DK98943842T DK98943842T DK1037648T3 DK 1037648 T3 DK1037648 T3 DK 1037648T3 DK 98943842 T DK98943842 T DK 98943842T DK 98943842 T DK98943842 T DK 98943842T DK 1037648 T3 DK1037648 T3 DK 1037648T3
- Authority
- DK
- Denmark
- Prior art keywords
- preparation
- preparations
- treatment
- erythropoietin
- iron
- Prior art date
Links
- 238000002360 preparation method Methods 0.000 title abstract 4
- 102000003951 Erythropoietin Human genes 0.000 title abstract 2
- 108090000394 Erythropoietin Proteins 0.000 title abstract 2
- 208000025747 Rheumatic disease Diseases 0.000 title abstract 2
- 229940105423 erythropoietin Drugs 0.000 title abstract 2
- OXCMYAYHXIHQOA-UHFFFAOYSA-N potassium;[2-butyl-5-chloro-3-[[4-[2-(1,2,4-triaza-3-azanidacyclopenta-1,4-dien-5-yl)phenyl]phenyl]methyl]imidazol-4-yl]methanol Chemical compound [K+].CCCCC1=NC(Cl)=C(CO)N1CC1=CC=C(C=2C(=CC=CC=2)C2=N[N-]N=N2)C=C1 OXCMYAYHXIHQOA-UHFFFAOYSA-N 0.000 title abstract 2
- 229940082629 iron antianemic preparations Drugs 0.000 title 1
- 239000000825 pharmaceutical preparation Substances 0.000 title 1
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 abstract 3
- 229910052742 iron Inorganic materials 0.000 abstract 2
- -1 iron ions Chemical class 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/1816—Erythropoietin [EPO]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Rheumatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Pain & Pain Management (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19734293A DE19734293A1 (de) | 1997-08-08 | 1997-08-08 | Verwendung von pharmazeutischen Kombinationspräparaten enthaltend Erythropoietin und Eisenpräparate zur Behandlung von rheumatischen Erkrankungen |
| PCT/EP1998/004864 WO1999007401A2 (de) | 1997-08-08 | 1998-08-05 | Verwendung von erythropoietin und eisenpräparaten zur herstellung von pharmazeutischen kombinationspräparaten zur behandlung von rheumatischen erkrankungen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1037648T3 true DK1037648T3 (da) | 2004-08-02 |
Family
ID=7838328
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK98943842T DK1037648T3 (da) | 1997-08-08 | 1998-08-05 | Anvendelse af erythropoietin og jernpræparater til fremstilling af farmaceutiske kombinationspræparater til behandling af rheumatiske lidelser |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US6372715B1 (da) |
| EP (1) | EP1037648B1 (da) |
| JP (3) | JP2001513510A (da) |
| KR (1) | KR100478573B1 (da) |
| CN (1) | CN1170589C (da) |
| AT (1) | ATE263571T1 (da) |
| AU (1) | AU738027B2 (da) |
| BR (1) | BR9811086A (da) |
| CA (1) | CA2297959C (da) |
| DE (2) | DE19734293A1 (da) |
| DK (1) | DK1037648T3 (da) |
| ES (1) | ES2218851T3 (da) |
| PT (1) | PT1037648E (da) |
| TR (1) | TR200000369T2 (da) |
| WO (1) | WO1999007401A2 (da) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT977582E (pt) * | 1997-03-18 | 2002-12-31 | Roche Diagnostics Gmbh | Preparacoes farmaceuticas associadas contendo eritropoietina e preparacoes de ferro |
| DE19734293A1 (de) * | 1997-08-08 | 1999-02-11 | Boehringer Mannheim Gmbh | Verwendung von pharmazeutischen Kombinationspräparaten enthaltend Erythropoietin und Eisenpräparate zur Behandlung von rheumatischen Erkrankungen |
| PL219131B1 (pl) * | 2000-05-15 | 2015-03-31 | Hoffmann La Roche | Ciekła kompozycja farmaceutyczna, sposób jej wytwarzania oraz jej zastosowanie |
| JP4369120B2 (ja) * | 2000-11-02 | 2009-11-18 | クロマシューティカル・アドヴァンスト・テクノロジーズ，インコーポレイテッド | 精製された造血性鉄−サッカリド錯体の生成方法およびそれによって生成した生成物 |
| US6929954B2 (en) | 2000-11-02 | 2005-08-16 | Chromaceutical Advanced Technologies, Inc. | Method for producing purified hematinic iron-saccharidic complex and product produced |
| CA2431964C (en) | 2000-12-20 | 2013-09-10 | F. Hoffmann-La Roche Ag | Conjugates of erythropoietin (pep) with polyethylene glycol (peg) |
| EP1909106B1 (en) | 2001-09-14 | 2013-01-02 | F. Hoffmann-La Roche AG | Differential diagnosis of disorders of iron metabolism by means of four parameters and recommendations for the treatment of these disorders of iron metabolism |
| US7459435B2 (en) * | 2002-08-29 | 2008-12-02 | Hoffmann-La Roche Inc. | Treatment of disturbances of iron distribution |
| US7459436B2 (en) * | 2002-11-22 | 2008-12-02 | Hoffmann-La Roche Inc. | Treatment of disturbances of iron distribution |
| US7964568B2 (en) * | 2003-05-30 | 2011-06-21 | Chromaceutical Advanced Technologies, Inc. | Synthesis of high molecular weight iron-saccharidic complexes |
| CA2597154C (en) * | 2005-02-09 | 2011-03-15 | Vifor (International) Ag | Use of iron(iii) complex compounds |
| CN102961746B (zh) | 2005-05-16 | 2016-06-15 | 艾伯维生物技术有限公司 | TNFα抑制剂治疗腐蚀性多关节炎的用途 |
| EP1790356A1 (de) * | 2005-11-24 | 2007-05-30 | Vifor (International) Ag | Präparat, umfassend Eisen(III)-Komplexverbindungen und redoxaktive Substanz(en) |
| US9605064B2 (en) | 2006-04-10 | 2017-03-28 | Abbvie Biotechnology Ltd | Methods and compositions for treatment of skin disorders |
| US9399061B2 (en) * | 2006-04-10 | 2016-07-26 | Abbvie Biotechnology Ltd | Methods for determining efficacy of TNF-α inhibitors for treatment of rheumatoid arthritis |
| US20080131374A1 (en) * | 2006-04-19 | 2008-06-05 | Medich John R | Uses and compositions for treatment of rheumatoid arthritis |
| PL2054074T3 (pl) | 2006-08-04 | 2015-03-31 | Prolong Pharmaceuticals Llc | Zmodyfikowana erytropoetyna |
| US20080132465A1 (en) * | 2006-12-05 | 2008-06-05 | Vincent Windisch | Apparatus and method for isolating iron components from serum |
| CL2008002054A1 (es) | 2007-07-17 | 2009-05-29 | Hoffmann La Roche | Metodo para la regeneracion de una columna de cromatografia de intercambio cationico despues de la elusion de eritropoyetina monopeguilada y metodo para obtener una eritropoyetina monopeguilada, incorporando el metodo de regeneracion de la columna de intercambio cationico. |
| CL2008002053A1 (es) * | 2007-07-17 | 2009-05-22 | Hoffmann La Roche | Metodo para la purificacion de una eritropoyetina monopeguilada (epompeg) que consiste en proporcionar una solucion que contiene eritropoyetina mono, poli y no peguilada y hacerla pasar por dos pasos de cromatografia de intercambio cationico y metodo para producir epo mpeg que incluye metodo de purificacion. |
| US20100040630A1 (en) * | 2008-03-24 | 2010-02-18 | Aake Elden | Methods and compositions for treating bone loss |
| US8202830B2 (en) | 2009-01-30 | 2012-06-19 | Ecolab Usa Inc. | Development of an aluminum hydroxydicarboxylate builder |
| AU2010209328B2 (en) * | 2009-01-30 | 2015-07-02 | Ecolab Inc. | Development of an aluminum hydroxycarboxylate builder |
| US8536106B2 (en) | 2010-04-14 | 2013-09-17 | Ecolab Usa Inc. | Ferric hydroxycarboxylate as a builder |
| JP6085401B2 (ja) * | 2014-07-25 | 2017-02-22 | 原 和弘 | 薬剤投与情報提供装置及び薬剤投与情報提供のためのコンピュータプログラム |
| PT3380487T (pt) | 2015-11-23 | 2020-10-29 | Bristol Myers Squibb Co | Sistemas de aditivos para utilização na peguilação de proteínas |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ194947A (en) * | 1979-09-18 | 1983-06-14 | C Holland | Composition containing calcium and ferrous ions for treatment of rheumatoid arthritis |
| US4732889A (en) * | 1985-02-06 | 1988-03-22 | Chugai Seiyaku Kabushiki Kaisha | Pharmaceutical composition for the treatment of the anemia of rheumatoid arthritis |
| EP0784480B1 (en) * | 1994-11-03 | 2003-10-15 | Boehringer Mannheim Gmbh | Use of erythropoietin in the treatment of rheumatoid arthritis |
| DE19535571A1 (de) * | 1995-09-14 | 1997-03-20 | Boehringer Mannheim Gmbh | Pharmazeutische Kombinationspräparate und deren Verwendung zur Behandlung von Hämodialysepatienten |
| DE19734293A1 (de) * | 1997-08-08 | 1999-02-11 | Boehringer Mannheim Gmbh | Verwendung von pharmazeutischen Kombinationspräparaten enthaltend Erythropoietin und Eisenpräparate zur Behandlung von rheumatischen Erkrankungen |
-
1997
- 1997-08-08 DE DE19734293A patent/DE19734293A1/de not_active Withdrawn
-
1998
- 1998-08-05 AU AU91590/98A patent/AU738027B2/en not_active Ceased
- 1998-08-05 WO PCT/EP1998/004864 patent/WO1999007401A2/de not_active Ceased
- 1998-08-05 BR BR9811086-1A patent/BR9811086A/pt not_active Application Discontinuation
- 1998-08-05 TR TR2000/00369T patent/TR200000369T2/xx unknown
- 1998-08-05 EP EP98943842A patent/EP1037648B1/de not_active Expired - Lifetime
- 1998-08-05 JP JP2000506990A patent/JP2001513510A/ja active Pending
- 1998-08-05 PT PT98943842T patent/PT1037648E/pt unknown
- 1998-08-05 ES ES98943842T patent/ES2218851T3/es not_active Expired - Lifetime
- 1998-08-05 DE DE59811158T patent/DE59811158D1/de not_active Expired - Lifetime
- 1998-08-05 US US09/485,371 patent/US6372715B1/en not_active Expired - Lifetime
- 1998-08-05 CA CA2297959A patent/CA2297959C/en not_active Expired - Fee Related
- 1998-08-05 DK DK98943842T patent/DK1037648T3/da active
- 1998-08-05 CN CNB98808516XA patent/CN1170589C/zh not_active Expired - Fee Related
- 1998-08-05 KR KR10-2000-7001335A patent/KR100478573B1/ko not_active Expired - Fee Related
- 1998-08-05 AT AT98943842T patent/ATE263571T1/de active
-
2008
- 2008-01-07 JP JP2008000665A patent/JP2008133290A/ja active Pending
-
2011
- 2011-09-30 JP JP2011218092A patent/JP2012012410A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| EP1037648B1 (de) | 2004-04-07 |
| KR100478573B1 (ko) | 2005-03-28 |
| JP2008133290A (ja) | 2008-06-12 |
| CN1268058A (zh) | 2000-09-27 |
| CA2297959C (en) | 2011-11-29 |
| ES2218851T3 (es) | 2004-11-16 |
| KR20010022738A (ko) | 2001-03-26 |
| JP2001513510A (ja) | 2001-09-04 |
| US6372715B1 (en) | 2002-04-16 |
| BR9811086A (pt) | 2000-08-29 |
| WO1999007401A2 (de) | 1999-02-18 |
| ATE263571T1 (de) | 2004-04-15 |
| CN1170589C (zh) | 2004-10-13 |
| PT1037648E (pt) | 2004-08-31 |
| JP2012012410A (ja) | 2012-01-19 |
| TR200000369T2 (tr) | 2000-09-21 |
| CA2297959A1 (en) | 1999-02-18 |
| WO1999007401A3 (de) | 1999-04-29 |
| DE19734293A1 (de) | 1999-02-11 |
| AU738027B2 (en) | 2001-09-06 |
| DE59811158D1 (de) | 2004-05-13 |
| EP1037648A2 (de) | 2000-09-27 |
| AU9159098A (en) | 1999-03-01 |
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