BR9908537A - Copolìmeros biocompatìveis e utilização dos mesmos - Google Patents

Copolìmeros biocompatìveis e utilização dos mesmos

Info

Publication number
BR9908537A
BR9908537A BR9908537-2A BR9908537A BR9908537A BR 9908537 A BR9908537 A BR 9908537A BR 9908537 A BR9908537 A BR 9908537A BR 9908537 A BR9908537 A BR 9908537A
Authority
BR
Brazil
Prior art keywords
copolymers
alkyl group
formula
biocompatible
integer
Prior art date
Application number
BR9908537-2A
Other languages
English (en)
Inventor
Nicole Bru-Magniez
Virginie Larras
Gerard Riess
Pascal Breton
Patrick Couvreur
Claude Roques-Carmes
Original Assignee
Virsol
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Virsol filed Critical Virsol
Publication of BR9908537A publication Critical patent/BR9908537A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G81/00—Macromolecular compounds obtained by interreacting polymers in the absence of monomers, e.g. block polymers
    • C08G81/02—Macromolecular compounds obtained by interreacting polymers in the absence of monomers, e.g. block polymers at least one of the polymers being obtained by reactions involving only carbon-to-carbon unsaturated bonds
    • C08G81/024—Block or graft polymers containing sequences of polymers of C08C or C08F and of polymers of C08G
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F297/00—Macromolecular compounds obtained by successively polymerising different monomer systems using a catalyst of the ionic or coordination type without deactivating the intermediate polymer
    • C08F297/02—Macromolecular compounds obtained by successively polymerising different monomer systems using a catalyst of the ionic or coordination type without deactivating the intermediate polymer using a catalyst of the anionic type
    • C08F297/026—Macromolecular compounds obtained by successively polymerising different monomer systems using a catalyst of the ionic or coordination type without deactivating the intermediate polymer using a catalyst of the anionic type polymerising acrylic acid, methacrylic acid or derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F290/00—Macromolecular compounds obtained by polymerising monomers on to polymers modified by introduction of aliphatic unsaturated end or side groups
    • C08F290/02—Macromolecular compounds obtained by polymerising monomers on to polymers modified by introduction of aliphatic unsaturated end or side groups on to polymers modified by introduction of unsaturated end groups
    • C08F290/06—Polymers provided for in subclass C08G
    • C08F290/062—Polyethers
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F297/00—Macromolecular compounds obtained by successively polymerising different monomer systems using a catalyst of the ionic or coordination type without deactivating the intermediate polymer
    • C08F297/02—Macromolecular compounds obtained by successively polymerising different monomer systems using a catalyst of the ionic or coordination type without deactivating the intermediate polymer using a catalyst of the anionic type
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G81/00—Macromolecular compounds obtained by interreacting polymers in the absence of monomers, e.g. block polymers
    • C08G81/02—Macromolecular compounds obtained by interreacting polymers in the absence of monomers, e.g. block polymers at least one of the polymers being obtained by reactions involving only carbon-to-carbon unsaturated bonds
    • C08G81/024—Block or graft polymers containing sequences of polymers of C08C or C08F and of polymers of C08G
    • C08G81/025—Block or graft polymers containing sequences of polymers of C08C or C08F and of polymers of C08G containing polyether sequences
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09K—MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
    • C09K23/00—Use of substances as emulsifying, wetting, dispersing, or foam-producing agents
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09K—MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
    • C09K23/00—Use of substances as emulsifying, wetting, dispersing, or foam-producing agents
    • C09K23/34—Higher-molecular-weight carboxylic acid esters
    • C09K23/36—Esters of polycarboxylic acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Other Resins Obtained By Reactions Not Involving Carbon-To-Carbon Unsaturated Bonds (AREA)
  • Graft Or Block Polymers (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Polyethers (AREA)
  • Materials For Medical Uses (AREA)
  • Emulsifying, Dispersing, Foam-Producing Or Wetting Agents (AREA)

Abstract

"COPOLìMEROS BIOCOMPATìVEIS E UTILIZAçãO DOS MESMOS" A presente invenção refere-se, de uma maneira geral, a uma nova família de copolímeros tensoativos biocompatíveis que apresentam um largo espectro de utilizações, notadamentente no domínio farmacêutico e para a síntese de materiais com estado disperso bem como o tratamento de superfície de materiais ou biomateriais. De acordo com a invenção, esses copolímeros são caracterizados pelo fato de que comportam uma seq³ência com caráter hidrófobo formada: seja por um homopolímero constituído por unidades recorrentes que correspondem à fórmula geral (I) na qual: R~ 1~ representa um grupo alquila tendo de 1 a 6 átomos de carbono ou um grupo (CH~ 2~ )m~ - COOR~ 3~ no qual m é um número inteiro compreendido entre 1 e 5 e R~ 3~ representa um grupo alquila tendo de 1 a 6 átomos de carbono, R~ 2~ representa um grupo alquila tendo de 1 a 6 átomos de carbono, e n é um número inteiro compreendido entre 1 e 5, seja de um copolímero estatístico constituído por unidades recorrentes diferentes que correspondem à fórmula (I) tal como definida anteriormente, seja enfim de um copolímero estatístico majoritariamente constituído por unidades que correspondem à fórmula (I) tal como definida anteriormente.
BR9908537-2A 1998-01-29 1999-01-29 Copolìmeros biocompatìveis e utilização dos mesmos BR9908537A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9801001A FR2774096B1 (fr) 1998-01-29 1998-01-29 Nouveaux copolymeres tensioactifs a base de methylidene malonate
PCT/FR1999/000185 WO1999038898A1 (fr) 1998-01-29 1999-01-29 Nouveaux copolymeres tensioactifs a base de methylidene malonate

Publications (1)

Publication Number Publication Date
BR9908537A true BR9908537A (pt) 2000-11-28

Family

ID=9522340

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9908537-2A BR9908537A (pt) 1998-01-29 1999-01-29 Copolìmeros biocompatìveis e utilização dos mesmos

Country Status (23)

Country Link
US (1) US6750298B1 (pt)
EP (1) EP1051436B1 (pt)
JP (1) JP2002501953A (pt)
KR (1) KR20010040476A (pt)
CN (1) CN1114633C (pt)
AR (1) AR018536A1 (pt)
AT (1) ATE253602T1 (pt)
AU (1) AU744995B2 (pt)
BR (1) BR9908537A (pt)
CA (1) CA2318828A1 (pt)
CZ (1) CZ294928B6 (pt)
DE (1) DE69912578T2 (pt)
ES (1) ES2211028T3 (pt)
FR (1) FR2774096B1 (pt)
HU (1) HUP0100238A3 (pt)
IL (1) IL137441A0 (pt)
NO (1) NO20003873D0 (pt)
NZ (1) NZ505946A (pt)
PL (1) PL341934A1 (pt)
RU (1) RU2216551C2 (pt)
SK (1) SK11042000A3 (pt)
WO (1) WO1999038898A1 (pt)
ZA (1) ZA99721B (pt)

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JP4611561B2 (ja) * 2000-04-12 2011-01-12 Ｄｉｃ株式会社 新規なビニル系樹脂およびその製造方法
GB2381792B (en) * 2000-04-12 2004-08-04 Dainippon Ink & Chemicals Antifouling coating composituion
KR100427725B1 (ko) * 2001-03-22 2004-04-27 광주과학기술원 나노 입자와 고분자 물질을 이용한 나노 복합체 제조 방법
ES2263844T3 (es) * 2001-12-07 2006-12-16 Hercules Incorporated Composicion que comprende fibra celulosica y un copolimero anionico soluble en agua asi como un metodo para obtener dicha composicion.
JP3961312B2 (ja) 2002-02-26 2007-08-22 株式会社デンソー 内燃機関の制御装置
DE10217439A1 (de) * 2002-04-18 2003-10-30 Basf Ag Verfahren zur Herstellung von Polyamiden
US20060039948A1 (en) * 2002-11-14 2006-02-23 Gunther Schmid Implant, therapeutic agent and micelle
WO2005070979A1 (de) * 2004-01-27 2005-08-04 Merck Patent Gmbh Verwendung von statistischen copolymeren
DE102004004209A1 (de) * 2004-01-27 2005-08-18 Merck Patent Gmbh Verwendung von statistischen Copolymeren
ITRM20060682A1 (it) * 2006-12-19 2008-06-20 Sicit Chemitech S P A Nuovi derivati polimerici biodegradabili
US8106234B2 (en) * 2009-05-07 2012-01-31 OptMed, Inc Methylidene malonate process
US8975435B2 (en) * 2009-05-07 2015-03-10 Optmed, Inc. Methylidene malonate process
US9828324B2 (en) 2010-10-20 2017-11-28 Sirrus, Inc. Methylene beta-diketone monomers, methods for making methylene beta-diketone monomers, polymerizable compositions and products formed therefrom
US10414839B2 (en) 2010-10-20 2019-09-17 Sirrus, Inc. Polymers including a methylene beta-ketoester and products formed therefrom
US9279022B1 (en) * 2014-09-08 2016-03-08 Sirrus, Inc. Solution polymers including one or more 1,1-disubstituted alkene compounds, solution polymerization methods, and polymer compositions
US9249265B1 (en) * 2014-09-08 2016-02-02 Sirrus, Inc. Emulsion polymers including one or more 1,1-disubstituted alkene compounds, emulsion methods, and polymer compositions
CA2815198A1 (en) 2010-10-20 2012-04-26 Bioformix Inc. Synthesis of methylene malonates using rapid recovery in the presence of a heat transfer agent
FR2969619B1 (fr) * 2010-12-23 2013-01-04 Arkema France Particules polymeriques filamenteuses et procede de preparation desdites particules par polymerisation radicalaire controlee en emulsion.
EP2768897B1 (en) 2011-10-19 2019-01-23 Sirrus, Inc. Methods for making methylene beta-diketone monomers
US9234107B2 (en) 2012-03-30 2016-01-12 Sirrus, Inc. Ink coating formulations and polymerizable systems for producing the same
CA2869112A1 (en) 2012-03-30 2013-10-03 Bioformix Inc. Composite and laminate articles and polymerizable systems for producing the same
CA2869108A1 (en) 2012-03-30 2013-10-03 Bioformix Inc. Methods for activating polymerizable compositions, polymerizable systems, and products formed thereby
WO2013181600A2 (en) 2012-06-01 2013-12-05 Bioformix Inc. Optical material and articles formed therefrom
WO2014078689A1 (en) 2012-11-16 2014-05-22 Bioformix Inc. Plastics bonding systems and methods
CN105164797B (zh) 2012-11-30 2019-04-19 瑟拉斯公司 用于电子应用的复合组合物
EP2943462B1 (en) 2013-01-11 2018-06-27 Sirrus, Inc. Method to obtain methylene malonate via bis(hydroxymethyl) malonate pathway
US9416091B1 (en) 2015-02-04 2016-08-16 Sirrus, Inc. Catalytic transesterification of ester compounds with groups reactive under transesterification conditions
US9315597B2 (en) 2014-09-08 2016-04-19 Sirrus, Inc. Compositions containing 1,1-disubstituted alkene compounds for preparing polymers having enhanced glass transition temperatures
US10501400B2 (en) 2015-02-04 2019-12-10 Sirrus, Inc. Heterogeneous catalytic transesterification of ester compounds with groups reactive under transesterification conditions
US9334430B1 (en) * 2015-05-29 2016-05-10 Sirrus, Inc. Encapsulated polymerization initiators, polymerization systems and methods using the same
US9217098B1 (en) 2015-06-01 2015-12-22 Sirrus, Inc. Electroinitiated polymerization of compositions having a 1,1-disubstituted alkene compound
US9518001B1 (en) 2016-05-13 2016-12-13 Sirrus, Inc. High purity 1,1-dicarbonyl substituted-1-alkenes and methods for their preparation
US10196481B2 (en) 2016-06-03 2019-02-05 Sirrus, Inc. Polymer and other compounds functionalized with terminal 1,1-disubstituted alkene monomer(s) and methods thereof
CN109153866A (zh) * 2016-06-03 2019-01-04 赛鲁斯股份有限公司 吸水性或水溶性聚合物、中间化合物及其方法
US9617377B1 (en) 2016-06-03 2017-04-11 Sirrus, Inc. Polyester macromers containing 1,1-dicarbonyl-substituted 1 alkenes
US10428177B2 (en) * 2016-06-03 2019-10-01 Sirrus, Inc. Water absorbing or water soluble polymers, intermediate compounds, and methods thereof
US9567475B1 (en) 2016-06-03 2017-02-14 Sirrus, Inc. Coatings containing polyester macromers containing 1,1-dicarbonyl-substituted 1 alkenes
US11591425B2 (en) 2017-06-02 2023-02-28 Arkema France Curable compositions and uses thereof
CN114127220B (zh) 2019-07-19 2024-01-19 阿科玛法国公司 可用于获得非致敏性的固化产品的可固化组合物

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FR2755136B1 (fr) * 1996-10-25 1999-01-22 Virsol Procede de preparation de nanoparticules de methylidene malonate, nanoparticules contenant eventuellement une ou plusieurs molecules biologiquement actives et compositions pharmaceutiques les contenant
FR2789314B1 (fr) * 1999-02-09 2001-04-27 Virsol Materiau de suture de plaies a base de methylidene malonate

Also Published As

Publication number Publication date
EP1051436A1 (fr) 2000-11-15
ZA99721B (en) 1999-07-29
DE69912578T2 (de) 2004-09-30
HUP0100238A2 (hu) 2001-06-28
ES2211028T3 (es) 2004-07-01
WO1999038898A1 (fr) 1999-08-05
DE69912578D1 (de) 2003-12-11
EP1051436B1 (fr) 2003-11-05
FR2774096B1 (fr) 2000-04-07
RU2216551C2 (ru) 2003-11-20
CZ20002747A3 (cs) 2001-01-17
SK11042000A3 (sk) 2001-04-09
KR20010040476A (ko) 2001-05-15
AR018536A1 (es) 2001-11-28
AU2168899A (en) 1999-08-16
NO20003873L (no) 2000-07-28
HUP0100238A3 (en) 2002-02-28
CN1289347A (zh) 2001-03-28
CZ294928B6 (cs) 2005-04-13
HK1034525A1 (en) 2001-10-26
PL341934A1 (en) 2001-05-07
NZ505946A (en) 2002-12-20
US6750298B1 (en) 2004-06-15
NO20003873D0 (no) 2000-07-28
AU744995B2 (en) 2002-03-07
ATE253602T1 (de) 2003-11-15
FR2774096A1 (fr) 1999-07-30
CA2318828A1 (en) 1999-08-05
CN1114633C (zh) 2003-07-16
IL137441A0 (en) 2001-07-24
JP2002501953A (ja) 2002-01-22

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Legal Events

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B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE AS 5A,6A, 7A E 8A ANUIDADES

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 1907 DE 24/07/2007.