BR9914930A - Construção de estirpes de produção para a preparação de fenóis substituìdos por inativação almejada de genes do catabolismo dos ácidos eugenólico e ferúlico - Google Patents

Construção de estirpes de produção para a preparação de fenóis substituìdos por inativação almejada de genes do catabolismo dos ácidos eugenólico e ferúlico

Info

Publication number
BR9914930A
BR9914930A BR9914930-3A BR9914930A BR9914930A BR 9914930 A BR9914930 A BR 9914930A BR 9914930 A BR9914930 A BR 9914930A BR 9914930 A BR9914930 A BR 9914930A
Authority
BR
Brazil
Prior art keywords
eugenolic
catabolism
genes
construction
preparation
Prior art date
Application number
BR9914930-3A
Other languages
English (en)
Inventor
Juergen Rabenhorst
Alexander Steinbuechel
Horst Priefert
Joerg Overhage
Original Assignee
Haarmann & Reimer Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Haarmann & Reimer Gmbh filed Critical Haarmann & Reimer Gmbh
Publication of BR9914930A publication Critical patent/BR9914930A/pt

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0071—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
    • C12N9/0083—Miscellaneous (1.14.99)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1025—Acyltransferases (2.3)
    • C12N9/1029—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88—Lyases (4.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y203/00—Acyltransferases (2.3)
    • C12Y203/01—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
    • C12Y203/01016—Acetyl-CoA C-acyltransferase (2.3.1.16)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)

Abstract

Patente de Invenção: <B>"CONSTRUçãO DE ESTIRPES DE PRODUçãO PARA A PREPARAçãO DE FENOIS SUBSTITUìDOS POR INATIVAçãO ALMEJADA DE GENES DO CATABOLISMO DOS áCIDOS EUGENóLICO E FERúLICO" A presente invenção refere-se a um organismo unicelular ou pluricelular transformado e/ou mutagenado, caracterizado pelo fato de que enzimas do catabolismo do ácido eugenólico e/ou do ácido ferúlico são desativadas de tal modo que ocorre um acúmulo do álcool coniferílico, do aldeído coniferílico, do ácido ferúlico, da vanilina e/ou do ácido vanilínico intermediários.
BR9914930-3A 1998-10-31 1999-10-20 Construção de estirpes de produção para a preparação de fenóis substituìdos por inativação almejada de genes do catabolismo dos ácidos eugenólico e ferúlico BR9914930A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19850242A DE19850242A1 (de) 1998-10-31 1998-10-31 Konstruktion von Produktionsstämmen für die Herstellung von substituierten Phenolen durch gezielte Inaktivierung von Genen des Eugenol- und Ferulasäure-Katabolismus
PCT/EP1999/007952 WO2000026355A2 (de) 1998-10-31 1999-10-20 Konstruktion von produktionsstämmen für die herstellung von substituierten phenolen durch gezielte inaktivierungen von genen des eugenol- und ferulasäure-katabolismus

Publications (1)

Publication Number Publication Date
BR9914930A true BR9914930A (pt) 2001-07-10

Family

ID=7886266

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9914930-3A BR9914930A (pt) 1998-10-31 1999-10-20 Construção de estirpes de produção para a preparação de fenóis substituìdos por inativação almejada de genes do catabolismo dos ácidos eugenólico e ferúlico

Country Status (14)

Country Link
EP (1) EP1124947A2 (pt)
JP (1) JP2003533166A (pt)
KR (1) KR20020022045A (pt)
CN (1) CN1325444A (pt)
AU (1) AU761093B2 (pt)
BR (1) BR9914930A (pt)
CA (1) CA2348962A1 (pt)
DE (1) DE19850242A1 (pt)
HK (1) HK1041902A1 (pt)
HU (1) HUP0104772A3 (pt)
IL (1) IL142272A0 (pt)
PL (1) PL348647A1 (pt)
SK (1) SK5742001A3 (pt)
WO (1) WO2000026355A2 (pt)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100830691B1 (ko) * 2006-11-21 2008-05-20 광주과학기술원 이소유제놀과 유제놀로부터 천연바닐린과 바닐린 산으로 생전환하는 신규 미생물
WO2012172108A1 (en) 2011-06-17 2012-12-20 Symrise Ag Microorganisms and methods for producing substituted phenols
EP3024939B1 (en) 2013-07-22 2018-11-28 Basf Se Genetic engineering of pseudomonas putida kt2440 for rapid and high yield production of vanillin from ferulic acid
CN103805640B (zh) * 2014-01-26 2016-04-06 东华大学 一种利用细菌氧化松伯醛制备阿魏酸的方法
PL3000888T3 (pl) * 2014-09-29 2019-05-31 Symrise Ag Sposób przekształcania kwasu ferulowego do waniliny
FR3041655B1 (fr) * 2015-09-29 2017-11-24 Lesaffre & Cie Nouvelles souches bacteriennes pour la production de vanilline
CN111019995B (zh) 2019-12-31 2021-04-27 厦门欧米克生物科技有限公司 一种以丁香酚为底物发酵生成香兰素的方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH05227980A (ja) * 1992-02-21 1993-09-07 Takasago Internatl Corp 発酵法によるバニリンおよびその関連化合物の製造法
DE4227076A1 (de) * 1992-08-17 1994-02-24 Haarmann & Reimer Gmbh Verfahren zur Herstellung substituierter Methoxyphenole und dafür geeignete Mikroorganismen
GB9606187D0 (en) * 1996-03-23 1996-05-29 Inst Of Food Research Production of vanillin
DE19649655A1 (de) * 1996-11-29 1998-06-04 Haarmann & Reimer Gmbh Syntheseenzyme für die Herstellung von Coniferylalkohol, Coniferylaldehyd, Ferulasäure, Vanillin und Vanillinsäure und deren Verwendung

Also Published As

Publication number Publication date
SK5742001A3 (en) 2001-12-03
CA2348962A1 (en) 2000-05-11
KR20020022045A (ko) 2002-03-23
EP1124947A2 (de) 2001-08-22
HUP0104772A2 (hu) 2002-03-28
IL142272A0 (en) 2002-03-10
HUP0104772A3 (en) 2003-10-28
WO2000026355A3 (de) 2000-11-09
PL348647A1 (en) 2002-06-03
AU761093B2 (en) 2003-05-29
WO2000026355A2 (de) 2000-05-11
HK1041902A1 (zh) 2002-07-26
DE19850242A1 (de) 2000-05-04
CN1325444A (zh) 2001-12-05
AU1041300A (en) 2000-05-22
JP2003533166A (ja) 2003-11-11

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B25A Requested transfer of rights approved

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B25D Requested change of name of applicant approved
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

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B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 1913 DE 04/09/2007.