BRPI0107761A - dispositivo osmótico, bem como método para fabricação do mesmo. - Google Patents

dispositivo osmótico, bem como método para fabricação do mesmo.

Info

Publication number
BRPI0107761A
BRPI0107761A BRPI0107761A BRPI0107761A BRPI0107761A BR PI0107761 A BRPI0107761 A BR PI0107761A BR PI0107761 A BRPI0107761 A BR PI0107761A BR PI0107761 A BRPI0107761 A BR PI0107761A BR PI0107761 A BRPI0107761 A BR PI0107761A
Authority
BR
Brazil
Prior art keywords
osmotic device
release
active agent
manufacturing
well
Prior art date
Application number
BRPI0107761A
Other languages
English (en)
Inventor
Joaquina Faour
Original Assignee
Osmotica Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Osmotica Corp filed Critical Osmotica Corp
Publication of BRPI0107761A publication Critical patent/BRPI0107761A/pt
Publication of BRPI0107761B1 publication Critical patent/BRPI0107761B1/pt
Publication of BRPI0107761B8 publication Critical patent/BRPI0107761B8/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0002Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0004Osmotic delivery systems; Sustained release driven by osmosis, thermal energy or gas

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Preparation (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • External Artificial Organs (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)

Abstract

"dispositivo osmótico que tem uma passagem pré-formada que aumenta de tamanho". a presente invenção provê um dispositivo osmótico simples e melhorado (1), que é capaz de prover uma liberação controlada de agente ativo contido no núcleo (4) através de uma passagem pré-formada (5) para um ambiente de uso. a passagem pré-formada (5) aumenta de tamanho durante o uso do dispositivo osmótico (1), desse modo aumentando a taxa de liberação do agente ativo, permitindo a liberação de partículas grandes contendo um agente ativo, e permitindo a liberação de agentes ativos que são substancialmente insolúveis no ambiente de uso.
BRPI0107761 2000-01-21 2001-01-08 dispositivo osmótico, bem como método para fabricação do mesmo. BRPI0107761B8 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US17742700P 2000-01-21 2000-01-21
US09/728,859 US6599284B2 (en) 2000-01-21 2000-11-30 Osmotic device having a preformed passageway that increases in size
PCT/US2001/000582 WO2001052819A1 (en) 2000-01-21 2001-01-08 Osmotic device having a preformed passageway that increases in size

Publications (3)

Publication Number Publication Date
BRPI0107761A true BRPI0107761A (pt) 2002-11-12
BRPI0107761B1 BRPI0107761B1 (pt) 2012-12-11
BRPI0107761B8 BRPI0107761B8 (pt) 2021-07-06

Family

ID=26873279

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0107761 BRPI0107761B8 (pt) 2000-01-21 2001-01-08 dispositivo osmótico, bem como método para fabricação do mesmo.

Country Status (14)

Country Link
US (1) US6599284B2 (pt)
EP (1) EP1248598B1 (pt)
AR (1) AR026148A1 (pt)
AT (1) ATE347881T1 (pt)
AU (1) AU2001227732A1 (pt)
BR (1) BRPI0107761B8 (pt)
CA (1) CA2395981C (pt)
DE (1) DE60125142T2 (pt)
DK (1) DK1248598T3 (pt)
ES (1) ES2277909T3 (pt)
MX (1) MXPA02007017A (pt)
PT (1) PT1248598E (pt)
UY (1) UY26546A1 (pt)
WO (1) WO2001052819A1 (pt)

Families Citing this family (105)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020131908A1 (en) * 2000-01-13 2002-09-19 George Benda Selective release apparatus for fluids
CA2725833A1 (en) * 2001-01-12 2002-07-18 Sun Pharmaceutical Industries Limited Spaced drug delivery system
KR200249057Y1 (ko) * 2001-03-22 2001-10-19 김진환 뚜껑, 받침대에 합체된 하수역류. 악취방지 장치
US20040156900A1 (en) * 2001-04-10 2004-08-12 Shanghvi Dilip Shantilal Time pulsed release composition
US7585283B2 (en) * 2001-07-12 2009-09-08 Given Imaging Ltd. Device and method for examining a body lumen
ES2501142T3 (es) * 2001-07-12 2014-10-01 Given Imaging Ltd. Dispositivo para examinar una cavidad interna corporal
US20030175346A1 (en) * 2002-02-01 2003-09-18 Anne Billotte Osmotic delivery system
GB0203296D0 (en) * 2002-02-12 2002-03-27 Glaxo Group Ltd Novel composition
ITMI20020514A1 (it) * 2002-03-12 2003-09-12 Jagotec Ag Sistema terapeutico per il rilascio controllato di uno o piu' principi attivi
ITMI20020515A1 (it) * 2002-03-12 2003-09-12 Jagotec Ag Sistema per il rilasco controllato di uno o piu' principi attivi
US8523788B2 (en) * 2002-07-11 2013-09-03 Given Imaging Ltd. Device, system and method for examining a body lumen
US20050208132A1 (en) * 2002-07-29 2005-09-22 Gayatri Sathyan Methods and dosage forms for reducing side effects of benzisozazole derivatives
US20050232995A1 (en) 2002-07-29 2005-10-20 Yam Nyomi V Methods and dosage forms for controlled delivery of paliperidone and risperidone
US9060941B2 (en) * 2002-09-20 2015-06-23 Actavis, Inc. Pharmaceutical formulation containing a biguanide and a thiazolidinedione derivative
US7959946B2 (en) * 2002-09-20 2011-06-14 Watson Pharmaceuticals, Inc. Pharmaceutical formulation containing a biguanide and a thiazolidinedione derivative
US7785627B2 (en) * 2002-09-20 2010-08-31 Watson Pharmaceuticals, Inc. Pharmaceutical formulation containing a biguanide and a thiazolidinedione derivative
US8084058B2 (en) 2002-09-20 2011-12-27 Watson Pharmaceuticals, Inc. Pharmaceutical formulation containing a biguanide and a thiazolidinedione derivative
US8293799B2 (en) * 2003-12-29 2012-10-23 Osmotica Keresleedelmo és Szolgáltató KFT Osmotic device containing a venlafaxine salt and a salt having an ion in common
US20060210633A1 (en) * 2003-04-03 2006-09-21 Sun Pharmaceutical Industries Limited Programmed drug delivery system
CN102525993B (zh) 2003-04-24 2017-04-12 佳高泰克有限公司 具有限定内核几何形状的缓释片剂
ATE445393T1 (de) * 2003-04-24 2009-10-15 Jagotec Ag Tablette mit gefärbtem kern
UY28326A1 (es) * 2003-05-22 2004-06-30 Osmotica Argentina S A Dispositivo de ruptura de liberacion controlada con un pasaje preformado
US20060177507A1 (en) * 2003-05-22 2006-08-10 Joaquina Faour Controlled release device containing lercanidipine
US8029822B2 (en) * 2003-05-22 2011-10-04 Osmotica Kereskedelmi és Seolgáltató KFT Rupturing controlled release device having a preformed passageway
US20050136108A1 (en) * 2003-08-22 2005-06-23 Yam Noymi V. Stepwise delivery of topiramate over prolonged period of time
US7611728B2 (en) * 2003-09-05 2009-11-03 Supernus Pharmaceuticals, Inc. Osmotic delivery of therapeutic compounds by solubility enhancement
DE10351448A1 (de) * 2003-11-04 2005-06-09 Bayer Healthcare Ag Geschmackstoffhaltige Arzneimittelformulierungen mit verbesserten pharmazeutischen Eigenschaften
AU2004296404A1 (en) * 2003-12-09 2005-06-23 Spherics, Inc. Bioadhesive polymers with catechol functionality
SE0401031D0 (sv) 2004-04-22 2004-04-22 Duocort Ab A new glucocorticoid replacement therapy
US8252331B2 (en) * 2004-12-03 2012-08-28 Osmotica Kereskedelmi és Szolgáltató, KFT Osmotic device containing amantadine and an osmotic salt
US8574626B2 (en) 2004-12-03 2013-11-05 Osmotica Kereskedelmi és Szolgáltató KFT Osmotic device containing amantadine and an osmotic salt
AR053986A1 (es) 2004-12-03 2007-05-30 Osmotica Pharmaceutical Argent Dispositivo osmotico que contiene amantadina y una sal osmotica
US8912908B2 (en) 2005-04-28 2014-12-16 Proteus Digital Health, Inc. Communication system with remote activation
US9198608B2 (en) 2005-04-28 2015-12-01 Proteus Digital Health, Inc. Communication system incorporated in a container
US8802183B2 (en) 2005-04-28 2014-08-12 Proteus Digital Health, Inc. Communication system with enhanced partial power source and method of manufacturing same
US8836513B2 (en) 2006-04-28 2014-09-16 Proteus Digital Health, Inc. Communication system incorporated in an ingestible product
CN102379684B (zh) 2005-04-28 2014-11-19 普罗透斯数字保健公司 药物信息系统
RU2408368C2 (ru) 2005-06-27 2011-01-10 Биовэйл Лэборэториз Интернэшнл С.Р.Л. Препараты соли бупропиона с модифицированным высвобождением
CN101291652A (zh) * 2005-06-29 2008-10-22 阿尔扎公司 对渗透剂型提供降低的干燥时间的半渗透性组合物
CA2650920C (en) 2006-05-02 2016-10-18 Proteus Biomedical, Inc. Patient customized therapeutic regimens
US7772390B1 (en) 2006-07-18 2010-08-10 The Regents Of The University Of California Lipid mediated nucleic acid synthesis
SG174026A1 (en) 2006-08-03 2011-09-29 Nitec Pharma Ag Delayed-release glucocorticoid treatment of rheumatoid disease
MY158019A (en) 2006-10-25 2016-08-30 Proteus Digital Health Inc Controlled activation ingestible identifier
US8718193B2 (en) 2006-11-20 2014-05-06 Proteus Digital Health, Inc. Active signal processing personal health signal receivers
PT3785599T (pt) 2007-02-01 2022-10-21 Otsuka Pharma Co Ltd Sistemas de marcadores de eventos ingeríveis
CA2676280C (en) * 2007-02-14 2018-05-22 Proteus Biomedical, Inc. In-body power source having high surface area electrode
US9270025B2 (en) 2007-03-09 2016-02-23 Proteus Digital Health, Inc. In-body device having deployable antenna
WO2008112577A1 (en) 2007-03-09 2008-09-18 Proteus Biomedical, Inc. In-body device having a multi-directional transmitter
US8115618B2 (en) 2007-05-24 2012-02-14 Proteus Biomedical, Inc. RFID antenna for in-body device
CA2690340C (en) * 2007-06-21 2015-10-20 Swelltec Limited Apparatus and method with hydrocarbon swellable and water swellable body
GB0711979D0 (en) * 2007-06-21 2007-08-01 Swelltec Ltd Method and apparatus
US20090004281A1 (en) * 2007-06-26 2009-01-01 Biovail Laboratories International S.R.L. Multiparticulate osmotic delivery system
US8637080B2 (en) * 2007-06-28 2014-01-28 Osmotica Kereskedelmi és Szolgáltató, KFT Rupturing controlled release device comprising a subcoat
DK2192946T3 (da) 2007-09-25 2022-11-21 Otsuka Pharma Co Ltd Kropsintern anordning med virtuel dipol signalforstærkning
US8258962B2 (en) 2008-03-05 2012-09-04 Proteus Biomedical, Inc. Multi-mode communication ingestible event markers and systems, and methods of using the same
US20090312627A1 (en) * 2008-06-16 2009-12-17 Matott Laura A Radio-labeled ingestible capsule
CA3039236C (en) 2008-07-08 2022-05-17 Proteus Digital Health, Inc. Ingestible event marker data framework
WO2010015840A1 (en) * 2008-08-08 2010-02-11 Cipla Limited Osmotic delivery device with modified release
CN104382598A (zh) 2008-08-13 2015-03-04 普罗透斯数字保健公司 一种产生识别器的方法
US20100068266A1 (en) * 2008-09-16 2010-03-18 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Ex vivo-modifiable multiple-release state final dosage form
US20100068153A1 (en) * 2008-09-16 2010-03-18 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Ex vivo activatable final dosage form
US20100069887A1 (en) * 2008-09-16 2010-03-18 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Multiple chamber ex vivo adjustable-release final dosage form
US20100068254A1 (en) * 2008-09-16 2010-03-18 Mahalaxmi Gita Bangera Modifying a medicament availability state of a final dosage form
US20100069821A1 (en) * 2008-09-16 2010-03-18 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Ex vivo modifiable medicament release-sites final dosage form
US20100068233A1 (en) * 2008-09-16 2010-03-18 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Modifiable dosage form
US20100068152A1 (en) * 2008-09-16 2010-03-18 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Ex vivo modifiable particle or polymeric based final dosage form
US20100068275A1 (en) * 2008-09-16 2010-03-18 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Personalizable dosage form
US20100068235A1 (en) * 2008-09-16 2010-03-18 Searete LLC, a limited liability corporation of Deleware Individualizable dosage form
SG172846A1 (en) 2009-01-06 2011-08-29 Proteus Biomedical Inc Ingestion-related biofeedback and personalized medical therapy method and system
EP3395333A1 (en) 2009-01-06 2018-10-31 Proteus Digital Health, Inc. Pharmaceutical dosages delivery system
AU2010207740B2 (en) * 2009-01-26 2016-06-16 Nitec Pharma Ag Delayed-release glucocorticoid treatment of asthma
NZ582836A (en) * 2009-01-30 2011-06-30 Nitec Pharma Ag Delayed-release glucocorticoid treatment of rheumatoid arthritis by improving signs and symptoms, showing major or complete clinical response and by preventing from joint damage
WO2010111403A2 (en) 2009-03-25 2010-09-30 Proteus Biomedical, Inc. Probablistic pharmacokinetic and pharmacodynamic modeling
NZ596292A (en) 2009-04-28 2014-04-30 Proteus Digital Health Inc Highly reliable ingestible event markers and methods for using the same
US9149423B2 (en) * 2009-05-12 2015-10-06 Proteus Digital Health, Inc. Ingestible event markers comprising an ingestible component
TWI517050B (zh) 2009-11-04 2016-01-11 普羅托斯數位健康公司 供應鏈管理之系統
EP2515759A4 (en) 2009-12-23 2015-01-21 Given Imaging Inc METHOD OF ASSESSING CONSTIPATION USING INGREDIENT CAPSULE
EP2555737A4 (en) 2010-04-07 2013-09-18 Proteus Digital Health Inc FORMABLE MINIATURE DEVICE
TWI557672B (zh) 2010-05-19 2016-11-11 波提亞斯數位康健公司 用於從製造商跟蹤藥物直到患者之電腦系統及電腦實施之方法、用於確認將藥物給予患者的設備及方法、患者介面裝置
JP2014504902A (ja) 2010-11-22 2014-02-27 プロテウス デジタル ヘルス, インコーポレイテッド 医薬品を有する摂取可能なデバイス
WO2015112603A1 (en) 2014-01-21 2015-07-30 Proteus Digital Health, Inc. Masticable ingestible product and communication system therefor
US9756874B2 (en) 2011-07-11 2017-09-12 Proteus Digital Health, Inc. Masticable ingestible product and communication system therefor
CA2842952C (en) 2011-07-21 2019-01-08 Proteus Digital Health, Inc. Mobile communication device, system, and method
US9235683B2 (en) 2011-11-09 2016-01-12 Proteus Digital Health, Inc. Apparatus, system, and method for managing adherence to a regimen
AU2013293234B2 (en) 2012-07-23 2017-08-31 Otsuka Pharmaceutical Co., Ltd. Techniques for manufacturing ingestible event markers comprising an ingestible component
CN102871982B (zh) * 2012-10-16 2014-09-10 中国科学院上海药物研究所 一种药物渗透泵制剂
DK2910013T3 (en) 2012-10-18 2018-08-06 Proteus Digital Health Inc Apparatus, system and method for adaptive optimization for power output and transmit power in a power source for a communication device
WO2014120669A1 (en) 2013-01-29 2014-08-07 Proteus Digital Health, Inc. Highly-swellable polymeric films and compositions comprising the same
US10175376B2 (en) 2013-03-15 2019-01-08 Proteus Digital Health, Inc. Metal detector apparatus, system, and method
JP6511439B2 (ja) 2013-06-04 2019-05-15 プロテウス デジタル ヘルス, インコーポレイテッド データ収集および転帰の査定のためのシステム、装置、および方法
US9796576B2 (en) 2013-08-30 2017-10-24 Proteus Digital Health, Inc. Container with electronically controlled interlock
JP6392355B2 (ja) * 2013-09-13 2018-09-19 アール.ピー.シェーラー テクノロジーズ、エルエルシー ペレット包含錠剤
US10084880B2 (en) 2013-11-04 2018-09-25 Proteus Digital Health, Inc. Social media networking based on physiologic information
US20150306230A1 (en) * 2014-04-28 2015-10-29 Celanese Acetate Llc Drug delivery vehicles comprising cellulose derivatives, starch derivatives, and combinations thereof
US10172800B2 (en) 2015-02-20 2019-01-08 Osmotica Kereskedelmi Es Szolgaltato Kft Controlled release dosage form with enhanced pharmacokinetics
WO2016132217A1 (en) 2015-02-20 2016-08-25 Osmotica Kereskedelmi Es Szolgaltato Kft Method of improving gaba-b receptor agonist therapy
US10300032B2 (en) 2015-02-20 2019-05-28 Osmotica Kereskedelmi Es Szolgaltato Kft Controlled release dosage form
US10987328B2 (en) 2015-02-20 2021-04-27 Osmotica Kereskedelmi Es Szolgaltato Kft Controlled release dosage form
US11051543B2 (en) 2015-07-21 2021-07-06 Otsuka Pharmaceutical Co. Ltd. Alginate on adhesive bilayer laminate film
MX2019000888A (es) 2016-07-22 2019-06-03 Proteus Digital Health Inc Percepcion y deteccion electromagnetica de marcadores de evento ingeribles.
TWI735689B (zh) 2016-10-26 2021-08-11 日商大塚製藥股份有限公司 製造含有可攝食性事件標記之膠囊之方法
US10213394B1 (en) 2018-02-15 2019-02-26 Osmotica Kereskedelmi és Szolgáltató Korlátolt Felelõsségû Társaság Composition and method for treating neurological disease
US10213393B1 (en) 2018-02-15 2019-02-26 Osmotica Kereskedelmi és Szolgáltató Korlátolt Feleõsségû Társaság Composition and method for treating neurological disease
US20190247331A1 (en) 2018-02-15 2019-08-15 Osmotica Kereskedelmi és Szolgáltató Korlátolt Felelõsségû Társaság Composition and method for treating neurological disease
IL296690B2 (en) * 2022-09-21 2024-12-01 Empire Drying Services LLC Rescue compositions for hypoglycemia

Family Cites Families (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3916899A (en) * 1973-04-25 1975-11-04 Alza Corp Osmotic dispensing device with maximum and minimum sizes for the passageway
US4285987A (en) * 1978-10-23 1981-08-25 Alza Corporation Process for manufacturing device with dispersion zone
US4449983A (en) * 1982-03-22 1984-05-22 Alza Corporation Simultaneous delivery of two drugs from unit delivery device
US4455143A (en) * 1982-03-22 1984-06-19 Alza Corporation Osmotic device for dispensing two different medications
US5082668A (en) * 1983-05-11 1992-01-21 Alza Corporation Controlled-release system with constant pushing source
US4765989A (en) * 1983-05-11 1988-08-23 Alza Corporation Osmotic device for administering certain drugs
US4595583A (en) * 1984-03-19 1986-06-17 Alza Corporation Delivery system controlled administration of beneficial agent to ruminants
US4615698A (en) * 1984-03-23 1986-10-07 Alza Corporation Total agent osmotic delivery system
US4627851A (en) * 1984-10-26 1986-12-09 Alza Corporation Colonic-therapeutic delivery system
US4685918A (en) * 1985-02-01 1987-08-11 Merck & Co., Inc. Lipid osmotic pump
US4693886A (en) * 1985-04-22 1987-09-15 Alza Corporation Osmotic device with inert core
US4857330A (en) * 1986-04-17 1989-08-15 Alza Corporation Chlorpheniramine therapy
US4960416A (en) * 1986-04-30 1990-10-02 Alza Corporation Dosage form with improved delivery capability
US4743248A (en) * 1986-08-11 1988-05-10 Alza Corporation Dosage form for delivering acid sensitive beneficial agent
US5108756A (en) * 1989-01-12 1992-04-28 Pfizer Inc. Dispensing devices powered by lyotropic liquid crystals
EP0386967B1 (en) * 1989-03-10 1995-07-12 Yamanouchi Pharmaceutical Co. Ltd. A drug-release controlling coating material for long acting formulations
US5776493A (en) * 1989-07-14 1998-07-07 Alza Corporation Oral osmotic device for delivery of nystatin with hydrogel driving member
US5273752A (en) 1989-07-18 1993-12-28 Alza Corporation Controlled release dispenser comprising beneficial agent
US5200197A (en) * 1989-11-16 1993-04-06 Alza Corporation Contraceptive pill
US5178866A (en) * 1990-03-23 1993-01-12 Alza Corporation Dosage form for delivering drug to the intestine
US5324280A (en) * 1990-04-02 1994-06-28 Alza Corporation Osmotic dosage system for delivering a formulation comprising liquid carrier and drug
US5221536A (en) * 1990-05-07 1993-06-22 Alza Corporation Dosage form indicated for the management of abnormal posture, tremor and involuntary movement
US5057321A (en) * 1990-06-13 1991-10-15 Alza Corporation Dosage form comprising drug and maltodextrin
US5240713A (en) 1991-09-27 1993-08-31 Alza Corporation Dual rate agent delivery device
US5200195A (en) * 1991-12-06 1993-04-06 Alza Corporation Process for improving dosage form delivery kinetics
US5266332A (en) * 1991-12-06 1993-11-30 Alza Corporation Method for administering anti-Parkinson drug
PT621032E (pt) * 1993-04-23 2001-01-31 Novartis Ag Dispositivo de distribuicao de libertacao controlada de farmaco
US5914131A (en) * 1994-07-07 1999-06-22 Alza Corporation Hydromorphone therapy
FR2723536A1 (fr) * 1994-08-11 1996-02-16 Seth Pawan Composition permettant une liberation selective d'un principe actif
US5718700A (en) * 1994-09-20 1998-02-17 Alza Corporation Exit means in dosage form
US5558879A (en) * 1995-04-28 1996-09-24 Andrx Pharmaceuticals, Inc. Controlled release formulation for water soluble drugs in which a passageway is formed in situ
IL128043A (en) * 1997-05-30 2004-08-31 Osmotica Corp Multi-layered osmotic device for controlled delivery of active agents
US6514530B2 (en) * 1997-09-09 2003-02-04 Alza Corporation Dosage form comprising means for changing drug delivery shape
AU765909C (en) * 1998-12-17 2004-09-23 Alza Corporation Conversion of liquid filled gelatin capsules into controlled release systems by multiple coatings

Also Published As

Publication number Publication date
DE60125142D1 (de) 2007-01-25
MXPA02007017A (es) 2004-03-10
DE60125142T2 (de) 2007-10-25
US6599284B2 (en) 2003-07-29
US20020099361A1 (en) 2002-07-25
BRPI0107761B1 (pt) 2012-12-11
UY26546A1 (es) 2001-10-25
EP1248598B1 (en) 2006-12-13
WO2001052819A1 (en) 2001-07-26
CA2395981A1 (en) 2001-07-26
AU2001227732A1 (en) 2001-07-31
PT1248598E (pt) 2007-03-30
AR026148A1 (es) 2003-01-29
EP1248598A4 (en) 2004-01-21
EP1248598A1 (en) 2002-10-16
ES2277909T3 (es) 2007-08-01
CA2395981C (en) 2008-07-08
ATE347881T1 (de) 2007-01-15
DK1248598T3 (da) 2007-03-05
BRPI0107761B8 (pt) 2021-07-06

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