BRPI0107761A - dispositivo osmótico, bem como método para fabricação do mesmo. - Google Patents

dispositivo osmótico, bem como método para fabricação do mesmo.

Info

Publication number
BRPI0107761A
BRPI0107761A BRPI0107761A BRPI0107761A BRPI0107761A BR PI0107761 A BRPI0107761 A BR PI0107761A BR PI0107761 A BRPI0107761 A BR PI0107761A BR PI0107761 A BRPI0107761 A BR PI0107761A BR PI0107761 A BRPI0107761 A BR PI0107761A
Authority
BR
Brazil
Prior art keywords
osmotic device
release
active agent
manufacturing
well
Prior art date
Application number
BRPI0107761A
Other languages
English (en)
Inventor
Joaquina Faour
Original Assignee
Osmotica Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Osmotica Corp filed Critical Osmotica Corp
Publication of BRPI0107761A publication Critical patent/BRPI0107761A/pt
Publication of BRPI0107761B1 publication Critical patent/BRPI0107761B1/pt
Publication of BRPI0107761B8 publication Critical patent/BRPI0107761B8/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0002Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0004Osmotic delivery systems; Sustained release driven by osmosis, thermal energy or gas

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Preparation (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • External Artificial Organs (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)

Abstract

"dispositivo osmótico que tem uma passagem pré-formada que aumenta de tamanho". a presente invenção provê um dispositivo osmótico simples e melhorado (1), que é capaz de prover uma liberação controlada de agente ativo contido no núcleo (4) através de uma passagem pré-formada (5) para um ambiente de uso. a passagem pré-formada (5) aumenta de tamanho durante o uso do dispositivo osmótico (1), desse modo aumentando a taxa de liberação do agente ativo, permitindo a liberação de partículas grandes contendo um agente ativo, e permitindo a liberação de agentes ativos que são substancialmente insolúveis no ambiente de uso.
BRPI0107761 2000-01-21 2001-01-08 dispositivo osmótico, bem como método para fabricação do mesmo. BRPI0107761B8 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US17742700P 2000-01-21 2000-01-21
US09/728,859 US6599284B2 (en) 2000-01-21 2000-11-30 Osmotic device having a preformed passageway that increases in size
PCT/US2001/000582 WO2001052819A1 (en) 2000-01-21 2001-01-08 Osmotic device having a preformed passageway that increases in size

Publications (3)

Publication Number Publication Date
BRPI0107761A true BRPI0107761A (pt) 2002-11-12
BRPI0107761B1 BRPI0107761B1 (pt) 2012-12-11
BRPI0107761B8 BRPI0107761B8 (pt) 2021-07-06

Family

ID=26873279

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0107761 BRPI0107761B8 (pt) 2000-01-21 2001-01-08 dispositivo osmótico, bem como método para fabricação do mesmo.

Country Status (14)

Country Link
US (1) US6599284B2 (pt)
EP (1) EP1248598B1 (pt)
AR (1) AR026148A1 (pt)
AT (1) ATE347881T1 (pt)
AU (1) AU2001227732A1 (pt)
BR (1) BRPI0107761B8 (pt)
CA (1) CA2395981C (pt)
DE (1) DE60125142T2 (pt)
DK (1) DK1248598T3 (pt)
ES (1) ES2277909T3 (pt)
MX (1) MXPA02007017A (pt)
PT (1) PT1248598E (pt)
UY (1) UY26546A1 (pt)
WO (1) WO2001052819A1 (pt)

Families Citing this family (105)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020131908A1 (en) * 2000-01-13 2002-09-19 George Benda Selective release apparatus for fluids
EP1738751B1 (en) * 2001-01-12 2011-05-11 Sun Pharma Advanced Research Company Ltd Spaced drug delivery system
KR200249057Y1 (ko) * 2001-03-22 2001-10-19 김진환 뚜껑, 받침대에 합체된 하수역류. 악취방지 장치
DK1377276T3 (da) * 2001-04-10 2012-01-02 Sun Pharma Advanced Res Co Ltd Beregning af puls-frigivelsessammensætning
US7585283B2 (en) * 2001-07-12 2009-09-08 Given Imaging Ltd. Device and method for examining a body lumen
AU2002317466B2 (en) * 2001-07-12 2008-02-28 Given Imaging Ltd Device and method for examining a body lumen
TW200302748A (en) * 2002-02-01 2003-08-16 Pfizer Prod Inc Osmotic delivery system
GB0203296D0 (en) * 2002-02-12 2002-03-27 Glaxo Group Ltd Novel composition
ITMI20020515A1 (it) * 2002-03-12 2003-09-12 Jagotec Ag Sistema per il rilasco controllato di uno o piu' principi attivi
ITMI20020514A1 (it) * 2002-03-12 2003-09-12 Jagotec Ag Sistema terapeutico per il rilascio controllato di uno o piu' principi attivi
US8523788B2 (en) * 2002-07-11 2013-09-03 Given Imaging Ltd. Device, system and method for examining a body lumen
US20050232995A1 (en) 2002-07-29 2005-10-20 Yam Nyomi V Methods and dosage forms for controlled delivery of paliperidone and risperidone
US20050208132A1 (en) * 2002-07-29 2005-09-22 Gayatri Sathyan Methods and dosage forms for reducing side effects of benzisozazole derivatives
US7785627B2 (en) 2002-09-20 2010-08-31 Watson Pharmaceuticals, Inc. Pharmaceutical formulation containing a biguanide and a thiazolidinedione derivative
US8084058B2 (en) 2002-09-20 2011-12-27 Watson Pharmaceuticals, Inc. Pharmaceutical formulation containing a biguanide and a thiazolidinedione derivative
US9060941B2 (en) * 2002-09-20 2015-06-23 Actavis, Inc. Pharmaceutical formulation containing a biguanide and a thiazolidinedione derivative
US7959946B2 (en) 2002-09-20 2011-06-14 Watson Pharmaceuticals, Inc. Pharmaceutical formulation containing a biguanide and a thiazolidinedione derivative
US8293799B2 (en) * 2003-12-29 2012-10-23 Osmotica Keresleedelmo és Szolgáltató KFT Osmotic device containing a venlafaxine salt and a salt having an ion in common
US20060210633A1 (en) * 2003-04-03 2006-09-21 Sun Pharmaceutical Industries Limited Programmed drug delivery system
CA2523158C (en) * 2003-04-24 2010-11-16 Jagotec Ag Delayed release tablet with defined core geometry
US20070148229A1 (en) * 2003-04-24 2007-06-28 Jagotec Ag Tablet with coloured core
US8029822B2 (en) * 2003-05-22 2011-10-04 Osmotica Kereskedelmi és Seolgáltató KFT Rupturing controlled release device having a preformed passageway
US20060177507A1 (en) * 2003-05-22 2006-08-10 Joaquina Faour Controlled release device containing lercanidipine
UY28326A1 (es) * 2003-05-22 2004-06-30 Osmotica Argentina S A Dispositivo de ruptura de liberacion controlada con un pasaje preformado
CA2536507A1 (en) * 2003-08-22 2005-03-10 Alza Corporation Stepwise delivery of topiramate over prolonged period of time
US7611728B2 (en) * 2003-09-05 2009-11-03 Supernus Pharmaceuticals, Inc. Osmotic delivery of therapeutic compounds by solubility enhancement
DE10351448A1 (de) * 2003-11-04 2005-06-09 Bayer Healthcare Ag Geschmackstoffhaltige Arzneimittelformulierungen mit verbesserten pharmazeutischen Eigenschaften
CA2549195A1 (en) * 2003-12-09 2005-06-23 Spherics, Inc. Bioadhesive polymers with catechol functionality
SE0401031D0 (sv) * 2004-04-22 2004-04-22 Duocort Ab A new glucocorticoid replacement therapy
US8574626B2 (en) 2004-12-03 2013-11-05 Osmotica Kereskedelmi és Szolgáltató KFT Osmotic device containing amantadine and an osmotic salt
US8252331B2 (en) * 2004-12-03 2012-08-28 Osmotica Kereskedelmi és Szolgáltató, KFT Osmotic device containing amantadine and an osmotic salt
AR053986A1 (es) 2004-12-03 2007-05-30 Osmotica Pharmaceutical Argent Dispositivo osmotico que contiene amantadina y una sal osmotica
US8836513B2 (en) 2006-04-28 2014-09-16 Proteus Digital Health, Inc. Communication system incorporated in an ingestible product
US8802183B2 (en) 2005-04-28 2014-08-12 Proteus Digital Health, Inc. Communication system with enhanced partial power source and method of manufacturing same
US9198608B2 (en) 2005-04-28 2015-12-01 Proteus Digital Health, Inc. Communication system incorporated in a container
US8912908B2 (en) 2005-04-28 2014-12-16 Proteus Digital Health, Inc. Communication system with remote activation
SI1889198T1 (sl) 2005-04-28 2015-02-27 Proteus Digital Health, Inc. Farma-informacijski sistem
EP1896002A4 (en) * 2005-06-27 2009-11-25 Biovail Lab Int Srl BUPROPIONAL SALT FORMULATIONS WITH MODIFIED RELEASE
CN101291652A (zh) * 2005-06-29 2008-10-22 阿尔扎公司 对渗透剂型提供降低的干燥时间的半渗透性组合物
KR20140018439A (ko) 2006-05-02 2014-02-12 프로테우스 디지털 헬스, 인코포레이티드 환자 주문형 치료법
US7772390B1 (en) 2006-07-18 2010-08-10 The Regents Of The University Of California Lipid mediated nucleic acid synthesis
SG174026A1 (en) 2006-08-03 2011-09-29 Nitec Pharma Ag Delayed-release glucocorticoid treatment of rheumatoid disease
SG175681A1 (en) * 2006-10-25 2011-11-28 Proteus Biomedical Inc Controlled activation ingestible identifier
EP2069004A4 (en) 2006-11-20 2014-07-09 Proteus Digital Health Inc PERSONAL HEALTH SIGNAL RECEIVERS WITH ACTIVE SIGNAL PROCESSING
JP5524626B2 (ja) 2007-02-01 2014-06-18 プロテウス デジタル ヘルス, インコーポレイテッド 摂取可能な事象マーカシステム
CN103066226B (zh) * 2007-02-14 2016-09-14 普罗透斯数字保健公司 具有高表面积电极的体内电源
WO2008112577A1 (en) 2007-03-09 2008-09-18 Proteus Biomedical, Inc. In-body device having a multi-directional transmitter
EP2063771A1 (en) 2007-03-09 2009-06-03 Proteus Biomedical, Inc. In-body device having a deployable antenna
US8115618B2 (en) 2007-05-24 2012-02-14 Proteus Biomedical, Inc. RFID antenna for in-body device
GB0711979D0 (en) * 2007-06-21 2007-08-01 Swelltec Ltd Method and apparatus
CA2690340C (en) * 2007-06-21 2015-10-20 Swelltec Limited Apparatus and method with hydrocarbon swellable and water swellable body
US20090004281A1 (en) * 2007-06-26 2009-01-01 Biovail Laboratories International S.R.L. Multiparticulate osmotic delivery system
US8637080B2 (en) * 2007-06-28 2014-01-28 Osmotica Kereskedelmi és Szolgáltató, KFT Rupturing controlled release device comprising a subcoat
DK2192946T3 (da) 2007-09-25 2022-11-21 Otsuka Pharma Co Ltd Kropsintern anordning med virtuel dipol signalforstærkning
ES2840773T3 (es) 2008-03-05 2021-07-07 Otsuka Pharma Co Ltd Sistemas y marcadores de eventos ingeribles de comunicación multimodo
US20090312627A1 (en) * 2008-06-16 2009-12-17 Matott Laura A Radio-labeled ingestible capsule
SG10201702853UA (en) 2008-07-08 2017-06-29 Proteus Digital Health Inc Ingestible event marker data framework
WO2010015840A1 (en) * 2008-08-08 2010-02-11 Cipla Limited Osmotic delivery device with modified release
US8540633B2 (en) 2008-08-13 2013-09-24 Proteus Digital Health, Inc. Identifier circuits for generating unique identifiable indicators and techniques for producing same
US20100068233A1 (en) * 2008-09-16 2010-03-18 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Modifiable dosage form
US20100068254A1 (en) * 2008-09-16 2010-03-18 Mahalaxmi Gita Bangera Modifying a medicament availability state of a final dosage form
US20100068235A1 (en) * 2008-09-16 2010-03-18 Searete LLC, a limited liability corporation of Deleware Individualizable dosage form
US20100068152A1 (en) * 2008-09-16 2010-03-18 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Ex vivo modifiable particle or polymeric based final dosage form
US20100069887A1 (en) * 2008-09-16 2010-03-18 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Multiple chamber ex vivo adjustable-release final dosage form
US20100069821A1 (en) * 2008-09-16 2010-03-18 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Ex vivo modifiable medicament release-sites final dosage form
US20100068153A1 (en) * 2008-09-16 2010-03-18 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Ex vivo activatable final dosage form
US20100068278A1 (en) * 2008-09-16 2010-03-18 Searete Llc, A Limited Liablity Corporation Of The State Of Delaware Ex vivo modifiable medicament release-associations
US20100068275A1 (en) * 2008-09-16 2010-03-18 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Personalizable dosage form
US8597186B2 (en) 2009-01-06 2013-12-03 Proteus Digital Health, Inc. Pharmaceutical dosages delivery system
US9883819B2 (en) 2009-01-06 2018-02-06 Proteus Digital Health, Inc. Ingestion-related biofeedback and personalized medical therapy method and system
EP2391369A1 (en) * 2009-01-26 2011-12-07 Nitec Pharma AG Delayed-release glucocorticoid treatment of asthma
NZ582836A (en) * 2009-01-30 2011-06-30 Nitec Pharma Ag Delayed-release glucocorticoid treatment of rheumatoid arthritis by improving signs and symptoms, showing major or complete clinical response and by preventing from joint damage
WO2010111403A2 (en) 2009-03-25 2010-09-30 Proteus Biomedical, Inc. Probablistic pharmacokinetic and pharmacodynamic modeling
KR101677698B1 (ko) 2009-04-28 2016-11-21 프로테우스 디지털 헬스, 인코포레이티드 고신뢰성 섭취가능 이벤트 마커들 및 이를 사용하는 방법
EP2432458A4 (en) * 2009-05-12 2014-02-12 Proteus Digital Health Inc ACCEPTABLE EVENT MARKER WITH SUGAR COMPONENT
TWI517050B (zh) 2009-11-04 2016-01-11 普羅托斯數位健康公司 供應鏈管理之系統
WO2011079050A2 (en) 2009-12-23 2011-06-30 The Smart Pill Corporation Method of evaluating constipation using an ingestible capsule
JP6463599B2 (ja) 2010-04-07 2019-02-06 プロテウス デジタル ヘルス, インコーポレイテッド 小型の摂取可能なデバイス
TWI557672B (zh) 2010-05-19 2016-11-11 波提亞斯數位康健公司 用於從製造商跟蹤藥物直到患者之電腦系統及電腦實施之方法、用於確認將藥物給予患者的設備及方法、患者介面裝置
JP2014504902A (ja) 2010-11-22 2014-02-27 プロテウス デジタル ヘルス, インコーポレイテッド 医薬品を有する摂取可能なデバイス
WO2015112603A1 (en) 2014-01-21 2015-07-30 Proteus Digital Health, Inc. Masticable ingestible product and communication system therefor
US9756874B2 (en) 2011-07-11 2017-09-12 Proteus Digital Health, Inc. Masticable ingestible product and communication system therefor
IN2014MN00183A (pt) 2011-07-21 2015-06-19 Proteus Digital Health Inc
US9235683B2 (en) 2011-11-09 2016-01-12 Proteus Digital Health, Inc. Apparatus, system, and method for managing adherence to a regimen
WO2014018454A1 (en) 2012-07-23 2014-01-30 Proteus Digital Health, Inc. Techniques for manufacturing ingestible event markers comprising an ingestible component
CN102871982B (zh) * 2012-10-16 2014-09-10 中国科学院上海药物研究所 一种药物渗透泵制剂
CA2888871C (en) 2012-10-18 2016-08-09 Proteus Digital Health, Inc. Apparatus, system, and method to adaptively optimize power dissipation and broadcast power in a power source for a communication device
WO2014120669A1 (en) 2013-01-29 2014-08-07 Proteus Digital Health, Inc. Highly-swellable polymeric films and compositions comprising the same
WO2014144738A1 (en) 2013-03-15 2014-09-18 Proteus Digital Health, Inc. Metal detector apparatus, system, and method
EP3968263A1 (en) 2013-06-04 2022-03-16 Otsuka Pharmaceutical Co., Ltd. System, apparatus and methods for data collection and assessing outcomes
US9796576B2 (en) 2013-08-30 2017-10-24 Proteus Digital Health, Inc. Container with electronically controlled interlock
JP6392355B2 (ja) * 2013-09-13 2018-09-19 アール.ピー.シェーラー テクノロジーズ、エルエルシー ペレット包含錠剤
US10084880B2 (en) 2013-11-04 2018-09-25 Proteus Digital Health, Inc. Social media networking based on physiologic information
US20150306230A1 (en) * 2014-04-28 2015-10-29 Celanese Acetate Llc Drug delivery vehicles comprising cellulose derivatives, starch derivatives, and combinations thereof
US10172800B2 (en) 2015-02-20 2019-01-08 Osmotica Kereskedelmi Es Szolgaltato Kft Controlled release dosage form with enhanced pharmacokinetics
WO2016132220A1 (en) 2015-02-20 2016-08-25 Osmotica Kereskedelmi Es Szolgaltato Kft Controlled release oral dosage form of gaba receptor agonist
US10987328B2 (en) 2015-02-20 2021-04-27 Osmotica Kereskedelmi Es Szolgaltato Kft Controlled release dosage form
US10300032B2 (en) 2015-02-20 2019-05-28 Osmotica Kereskedelmi Es Szolgaltato Kft Controlled release dosage form
US11051543B2 (en) 2015-07-21 2021-07-06 Otsuka Pharmaceutical Co. Ltd. Alginate on adhesive bilayer laminate film
WO2018018034A1 (en) 2016-07-22 2018-01-25 Proteus Digital Health, Inc. Electromagnetic sensing and detection of ingestible event markers
IL265827B2 (en) 2016-10-26 2023-03-01 Proteus Digital Health Inc Methods for producing capsules with ingestible event markers
US10213394B1 (en) 2018-02-15 2019-02-26 Osmotica Kereskedelmi és Szolgáltató Korlátolt Felelõsségû Társaság Composition and method for treating neurological disease
US20190247331A1 (en) 2018-02-15 2019-08-15 Osmotica Kereskedelmi és Szolgáltató Korlátolt Felelõsségû Társaság Composition and method for treating neurological disease
US10213393B1 (en) 2018-02-15 2019-02-26 Osmotica Kereskedelmi és Szolgáltató Korlátolt Feleõsségû Társaság Composition and method for treating neurological disease
IL296690B2 (en) * 2022-09-21 2024-12-01 Empire Drying Services LLC Rescue compositions for hypoglycemia

Family Cites Families (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3916899A (en) * 1973-04-25 1975-11-04 Alza Corp Osmotic dispensing device with maximum and minimum sizes for the passageway
US4285987A (en) * 1978-10-23 1981-08-25 Alza Corporation Process for manufacturing device with dispersion zone
US4449983A (en) * 1982-03-22 1984-05-22 Alza Corporation Simultaneous delivery of two drugs from unit delivery device
US4455143A (en) * 1982-03-22 1984-06-19 Alza Corporation Osmotic device for dispensing two different medications
US4765989A (en) * 1983-05-11 1988-08-23 Alza Corporation Osmotic device for administering certain drugs
US5082668A (en) * 1983-05-11 1992-01-21 Alza Corporation Controlled-release system with constant pushing source
US4595583A (en) * 1984-03-19 1986-06-17 Alza Corporation Delivery system controlled administration of beneficial agent to ruminants
US4615698A (en) * 1984-03-23 1986-10-07 Alza Corporation Total agent osmotic delivery system
US4627851A (en) * 1984-10-26 1986-12-09 Alza Corporation Colonic-therapeutic delivery system
US4685918A (en) * 1985-02-01 1987-08-11 Merck & Co., Inc. Lipid osmotic pump
US4693886A (en) * 1985-04-22 1987-09-15 Alza Corporation Osmotic device with inert core
US4857330A (en) * 1986-04-17 1989-08-15 Alza Corporation Chlorpheniramine therapy
US4960416A (en) * 1986-04-30 1990-10-02 Alza Corporation Dosage form with improved delivery capability
US4743248A (en) * 1986-08-11 1988-05-10 Alza Corporation Dosage form for delivering acid sensitive beneficial agent
US5108756A (en) * 1989-01-12 1992-04-28 Pfizer Inc. Dispensing devices powered by lyotropic liquid crystals
DK0386967T3 (da) * 1989-03-10 1995-11-20 Yamanouchi Pharma Co Ltd Coatingmateriale til styring af lægemiddelafgivelse i langtidsvirkende formuleringer
US5776493A (en) * 1989-07-14 1998-07-07 Alza Corporation Oral osmotic device for delivery of nystatin with hydrogel driving member
US5273752A (en) 1989-07-18 1993-12-28 Alza Corporation Controlled release dispenser comprising beneficial agent
US5200197A (en) * 1989-11-16 1993-04-06 Alza Corporation Contraceptive pill
US5178866A (en) * 1990-03-23 1993-01-12 Alza Corporation Dosage form for delivering drug to the intestine
US5324280A (en) * 1990-04-02 1994-06-28 Alza Corporation Osmotic dosage system for delivering a formulation comprising liquid carrier and drug
US5221536A (en) * 1990-05-07 1993-06-22 Alza Corporation Dosage form indicated for the management of abnormal posture, tremor and involuntary movement
US5057321A (en) * 1990-06-13 1991-10-15 Alza Corporation Dosage form comprising drug and maltodextrin
US5240713A (en) 1991-09-27 1993-08-31 Alza Corporation Dual rate agent delivery device
US5200195A (en) * 1991-12-06 1993-04-06 Alza Corporation Process for improving dosage form delivery kinetics
US5266332A (en) * 1991-12-06 1993-11-30 Alza Corporation Method for administering anti-Parkinson drug
EP0621032B1 (en) * 1993-04-23 2000-08-09 Novartis AG Controlled release drug delivery device
US5914131A (en) * 1994-07-07 1999-06-22 Alza Corporation Hydromorphone therapy
FR2723536A1 (fr) * 1994-08-11 1996-02-16 Seth Pawan Composition permettant une liberation selective d'un principe actif
US5718700A (en) * 1994-09-20 1998-02-17 Alza Corporation Exit means in dosage form
US5558879A (en) * 1995-04-28 1996-09-24 Andrx Pharmaceuticals, Inc. Controlled release formulation for water soluble drugs in which a passageway is formed in situ
CA2261787C (en) * 1997-05-30 2006-11-14 Laboratorios Phoenix U.S.A., Inc. Multi-layered osmotic device
US6514530B2 (en) * 1997-09-09 2003-02-04 Alza Corporation Dosage form comprising means for changing drug delivery shape
DK1140012T3 (da) * 1998-12-17 2004-07-12 Alza Corp Omdannelse af væskefyldte gelatinekapsler til systemer til kontrolleret frigivelsessystemer ved flere coatinger

Also Published As

Publication number Publication date
AR026148A1 (es) 2003-01-29
DE60125142D1 (de) 2007-01-25
PT1248598E (pt) 2007-03-30
CA2395981A1 (en) 2001-07-26
AU2001227732A1 (en) 2001-07-31
BRPI0107761B8 (pt) 2021-07-06
EP1248598B1 (en) 2006-12-13
DK1248598T3 (da) 2007-03-05
US6599284B2 (en) 2003-07-29
UY26546A1 (es) 2001-10-25
DE60125142T2 (de) 2007-10-25
MXPA02007017A (es) 2004-03-10
ATE347881T1 (de) 2007-01-15
BRPI0107761B1 (pt) 2012-12-11
EP1248598A1 (en) 2002-10-16
WO2001052819A1 (en) 2001-07-26
US20020099361A1 (en) 2002-07-25
ES2277909T3 (es) 2007-08-01
CA2395981C (en) 2008-07-08
EP1248598A4 (en) 2004-01-21

Similar Documents

Publication Publication Date Title
BRPI0107761A (pt) dispositivo osmótico, bem como método para fabricação do mesmo.
BRPI0418252A (pt) dispositivo de proteção respiratória pessoal, e, método de fazer o mesmo
BRPI0518973A2 (pt) xampu condicionador contendo partÍculas de silicone estabilizadas
BRPI0415505A (pt) agente terapêutico para mesotelioma
CL2008002407A1 (es) Forma de dosificacion oral que comprende al menos un agente activo de nicotina, al menos un material bioadhesivo capaz de formar un enlace de hidrogeno con el agente activo de nicotina, y al menos un agente de impacto sensorial que se libere rapidamente; y su uso para proporcionar alivio rapido de las ansias de nicotina (div. sol. 1825-04).
AR033059A1 (es) Preparados de insulina exentos de zinc y pobres en zinc, con estabilidad mejorada.
BRPI0505524A (pt) método passìvel de utilização com um poço subterráneo, sistema passìvel de utilização com um poço subterráneo, e ferramenta passìvel de utilização com um poço subterráneo
PE20050775A1 (es) Formulaciones que comprenden multiparticulas de liberacion controlada
BR0110751A (pt) Dispositivo
BR0209866A (pt) Aparelho de retenção para uso em um conjunto de borda de poço e método para a utilização do mesmo
ES2139877T3 (es) Agente anti-incrustacion.
BRPI0412975A (pt) espuma penetrante para uso farmacêutico
BRPI0713327A2 (pt) Dispositivo de liberação tendo polímeros dendríticos de auto-motagem e método de uso deste
ES2152990T3 (es) Principios activos y microparticulas que contienen gases.
BR9915072A (pt) Processo de encapsulação de um agente quìmico, composição contendo um agente quìmico, e, suspensão em um solvente aquoso de uma composição
PA8497901A1 (es) Sistemas y metodos para aerosolizar formulaciones farmaceuticas.
MXPA05012319A (es) Suministro de compuestos con celulas sanguineas rehidratadas.
MXPA03008062A (es) Composiciones desodorantes y antitranspirantes anhidras que contienen un agente dermoactivo solido soluble en el agua.
BRPI0611066A2 (pt) Método e método de cimentação
EP1279035A4 (en) TEST SUBSTANCE FOR HEMATOLOGICAL ANALYSIS AND PROCESS FOR PREPARING THE TEST SUBSTANCE
BR0207497A (pt) Dispositivo que pode ser retido em uma geometria para cavidades corporais
BRPI0414305A (pt) sistema de liberação de drogas por via oral
BRPI0410546A (pt) dispositivo de ruptura de liberação controlada com uma passagem pré-formada
MXPA02011509A (es) Apoyo artificial para escalar que comprende un sistema de seguridad que impide que escombros caigan en caso de una rotura.
CR7598A (es) Preparaciones farmaceuticas para uso por via oral que contienen resinas de intercambio de iones cargadas con ingredientes activos asi como agentes gelificantes intrinsecamente viscosos como agentes espesantes

Legal Events

Date Code Title Description
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B25A Requested transfer of rights approved

Owner name: OSMOTICA KERESKEDELMI ES SZOLGALGATO KFT (HU)

Free format text: TRANSFERIDO DE: OSMOTICA CORP.

B09A Decision: intention to grant [chapter 9.1 patent gazette]
B09X Republication of the decision to grant [chapter 9.1.3 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 11/12/2012, OBSERVADAS AS DEMAIS CONDICOES LEGAIS.

B25G Requested change of headquarter approved
B16C Correction of notification of the grant [chapter 16.3 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 08/01/01, OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF, QUE DETERMINA A ALTERACAO DO PRAZO DE CONCESSAO

B21F Lapse acc. art. 78, item iv - on non-payment of the annual fees in time

Free format text: REFERENTE A 22A ANUIDADE.

B24J Lapse because of non-payment of annual fees (definitively: art 78 iv lpi, resolution 113/2013 art. 12)

Free format text: EM VIRTUDE DA EXTINCAO PUBLICADA NA RPI 2704 DE 01-11-2022 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDA A EXTINCAO DA PATENTE E SEUS CERTIFICADOS, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.