BRPI0415505A - agente terapêutico para mesotelioma - Google Patents

agente terapêutico para mesotelioma

Info

Publication number
BRPI0415505A
BRPI0415505A BRPI0415505-0A BRPI0415505A BRPI0415505A BR PI0415505 A BRPI0415505 A BR PI0415505A BR PI0415505 A BRPI0415505 A BR PI0415505A BR PI0415505 A BRPI0415505 A BR PI0415505A
Authority
BR
Brazil
Prior art keywords
therapeutic agent
mesothelioma
mesothelioma therapeutic
interleukin
antagonist
Prior art date
Application number
BRPI0415505-0A
Other languages
English (en)
Inventor
Norihiro Nishimoto
Tadamitsu Kishimoto
Yasuo Adachi
Koichi Takayama
Original Assignee
Chugai Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34463281&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BRPI0415505(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Chugai Pharmaceutical Co Ltd filed Critical Chugai Pharmaceutical Co Ltd
Publication of BRPI0415505A publication Critical patent/BRPI0415505A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244—Interleukins [IL]
    • C07K16/248—IL-6
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Epidemiology (AREA)
  • Biophysics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Mobile Radio Communication Systems (AREA)

Abstract

"AGENTE TERAPêUTICO PARA MESOTELIOMA". A presente invenção proporciona um agente terapêutico para mesotelioma que contém um antagonista de interleucina-6 (IL-6) tal como anticorpo para receptor de IL-6 (IL-6R), e um inibidor de crescimento celular de mesotelioma que contém um antagonista de IL-6 tal como anticorpo para IL-6R.
BRPI0415505-0A 2003-10-17 2004-10-15 agente terapêutico para mesotelioma BRPI0415505A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2003358152 2003-10-17
PCT/JP2004/015674 WO2005037315A1 (ja) 2003-10-17 2004-10-15 中皮腫治療剤

Publications (1)

Publication Number Publication Date
BRPI0415505A true BRPI0415505A (pt) 2006-12-12

Family

ID=34463281

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0415505-0A BRPI0415505A (pt) 2003-10-17 2004-10-15 agente terapêutico para mesotelioma

Country Status (22)

Country Link
US (2) US20070134242A1 (pt)
EP (1) EP1690550B1 (pt)
JP (1) JP4651541B2 (pt)
KR (1) KR101193708B1 (pt)
CN (1) CN1874790B (pt)
AR (1) AR046290A1 (pt)
AU (1) AU2004281139B2 (pt)
BR (1) BRPI0415505A (pt)
CA (1) CA2542691C (pt)
DK (1) DK1690550T3 (pt)
ES (1) ES2392824T3 (pt)
IL (1) IL174909A (pt)
MX (1) MXPA06003768A (pt)
MY (1) MY149856A (pt)
NO (1) NO20061906L (pt)
NZ (1) NZ546557A (pt)
PL (1) PL1690550T3 (pt)
RU (2) RU2554942C2 (pt)
SI (1) SI1690550T1 (pt)
TW (1) TWI350175B (pt)
WO (1) WO2005037315A1 (pt)
ZA (1) ZA200602973B (pt)

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EP3269738A1 (en) 2004-03-24 2018-01-17 Chugai Seiyaku Kabushiki Kaisha Subtypes of humanized antibody against interleukin-6 receptor
US8470316B2 (en) 2005-10-14 2013-06-25 Chugai Seiyaku Kabushiki Kaisha Agents for suppressing damage to transplanted islets after islet transplantation
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JP5754875B2 (ja) 2006-04-07 2015-07-29 国立大学法人大阪大学 筋再生促進剤
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US7906117B2 (en) 2007-05-21 2011-03-15 Alderbio Holdings Llc Antagonists of IL-6 to prevent or treat cachexia, weakness, fatigue, and/or fever
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US9701747B2 (en) 2007-05-21 2017-07-11 Alderbio Holdings Llc Method of improving patient survivability and quality of life by anti-IL-6 antibody administration
EP3127921A1 (en) 2007-09-26 2017-02-08 Chugai Seiyaku Kabushiki Kaisha Method of modifying isoelectric point of antibody via amino acid substition in cdr
ES2687808T3 (es) 2007-09-26 2018-10-29 Chugai Seiyaku Kabushiki Kaisha Región constante de anticuerpo modificado
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US9212223B2 (en) 2008-11-25 2015-12-15 Alderbio Holdings Llc Antagonists of IL-6 to prevent or treat thrombosis
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US8323649B2 (en) * 2008-11-25 2012-12-04 Alderbio Holdings Llc Antibodies to IL-6 and use thereof
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Also Published As

Publication number Publication date
CN1874790B (zh) 2011-11-16
CA2542691A1 (en) 2005-04-28
SI1690550T1 (sl) 2012-12-31
TWI350175B (en) 2011-10-11
NZ546557A (en) 2010-01-29
AR046290A1 (es) 2005-11-30
MY149856A (en) 2013-10-31
AU2004281139B2 (en) 2011-01-20
RU2554942C2 (ru) 2015-07-10
ZA200602973B (en) 2007-07-25
RU2010102911A (ru) 2011-08-10
HK1096588A1 (en) 2007-06-08
KR101193708B1 (ko) 2012-10-22
WO2005037315A1 (ja) 2005-04-28
US8802092B2 (en) 2014-08-12
EP1690550B1 (en) 2012-08-08
MXPA06003768A (es) 2006-06-23
CN1874790A (zh) 2006-12-06
KR20070029632A (ko) 2007-03-14
ES2392824T3 (es) 2012-12-14
TW200517126A (en) 2005-06-01
IL174909A (en) 2010-11-30
NO20061906L (no) 2006-06-21
DK1690550T3 (da) 2012-11-05
AU2004281139A1 (en) 2005-04-28
JPWO2005037315A1 (ja) 2006-12-28
EP1690550A1 (en) 2006-08-16
US20070134242A1 (en) 2007-06-14
EP1690550A4 (en) 2009-07-15
PL1690550T3 (pl) 2013-01-31
US20080274106A1 (en) 2008-11-06
JP4651541B2 (ja) 2011-03-16
RU2006116896A (ru) 2007-12-10
CA2542691C (en) 2013-09-24
IL174909A0 (en) 2006-08-20
RU2392967C2 (ru) 2010-06-27

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