BRPI0215394B8 - composição compreendendo polissacarídeos deriváveis de aloe vera, extrato nag-25, extrato ultrafiltrado de aloe, seus processos de preparação, suas formas de dosagens, e seus usos - Google Patents

composição compreendendo polissacarídeos deriváveis de aloe vera, extrato nag-25, extrato ultrafiltrado de aloe, seus processos de preparação, suas formas de dosagens, e seus usos

Info

Publication number
BRPI0215394B8
BRPI0215394B8 BRPI0215394A BR0215394A BRPI0215394B8 BR PI0215394 B8 BRPI0215394 B8 BR PI0215394B8 BR PI0215394 A BRPI0215394 A BR PI0215394A BR 0215394 A BR0215394 A BR 0215394A BR PI0215394 B8 BRPI0215394 B8 BR PI0215394B8
Authority
BR
Brazil
Prior art keywords
extract
composition
aloe
aloe vera
polysaccharides
Prior art date
Application number
BRPI0215394A
Other languages
English (en)
Other versions
BR0215394B1 (pt
BR0215394A (pt
Inventor
Frieda Goedbloed Annelize
Jan Robbert Koumans Floris
Van Dijk Willem
Original Assignee
2Qr Res Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 2Qr Res Bv filed Critical 2Qr Res Bv
Publication of BR0215394A publication Critical patent/BR0215394A/pt
Publication of BR0215394B1 publication Critical patent/BR0215394B1/pt
Publication of BRPI0215394B8 publication Critical patent/BRPI0215394B8/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/105—Plant extracts, their artificial duplicates or their derivatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/886—Aloeaceae (Aloe family), e.g. aloe vera
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73—Polysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/54—Polymers characterized by specific structures/properties
    • A61K2800/542—Polymers characterized by specific structures/properties characterized by the charge
    • A61K2800/5424—Polymers characterized by specific structures/properties characterized by the charge anionic

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Polymers & Plastics (AREA)
  • Mycology (AREA)
  • Botany (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Materials Engineering (AREA)
  • Biochemistry (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Birds (AREA)
  • Communicable Diseases (AREA)
  • Medical Informatics (AREA)
  • Microbiology (AREA)
  • Oncology (AREA)
  • Dermatology (AREA)
  • Nutrition Science (AREA)
  • Food Science & Technology (AREA)
  • Biotechnology (AREA)
  • Virology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)

Abstract

"polissacarídeo negativamente carregado derivável de aloe vera". a presente invenção refere-se a uma nova composição de matéria é fornecida compreendendo polissacarídeos negativamente carregados que podem ser derivados de aloe vera e um processo para preparar essa composição de matéria por subfracionamento de um extrato de aloe vera, passando a subfração formada em uma coluna positivamente carregada e eluindo a mesma com uma solução de sal. opcionalmente, aloe vera é pré-purificada em uma coluna de sephadex g-25. esta composição de matéria e também o extrato compreendendo a mesma que é formada depois da pré-purificação ou ultrafiltração de um extrato de aloe vera é útil como um suplemento alimentar ou em alimentos dietéticos, para uso em cuidado pessoal e em cosméticos, especialmente para prevenir uma infecção com as bactérias helicobacter pylori, pseudomonas aeruginosa, streptococcus mutans ou streptococcus sanguis.
BRPI0215394A 2001-12-27 2002-12-23 composição compreendendo polissacarídeos deriváveis de aloe vera, extrato nag-25, extrato ultrafiltrado de aloe, seus processos de preparação, suas formas de dosagens, e seus usos BRPI0215394B8 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP01205253A EP1323738A1 (en) 2001-12-27 2001-12-27 Negatively charged polysaccharide derivable form Aloe Vera
EP01205253.6 2001-12-27
PCT/NL2002/000868 WO2003055918A1 (en) 2001-12-27 2002-12-23 Negatively charged polysaccharide derivable from aloe vera

Publications (3)

Publication Number Publication Date
BR0215394A BR0215394A (pt) 2005-04-05
BR0215394B1 BR0215394B1 (pt) 2014-07-22
BRPI0215394B8 true BRPI0215394B8 (pt) 2021-05-25

Family

ID=8181567

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0215394A BRPI0215394B8 (pt) 2001-12-27 2002-12-23 composição compreendendo polissacarídeos deriváveis de aloe vera, extrato nag-25, extrato ultrafiltrado de aloe, seus processos de preparação, suas formas de dosagens, e seus usos

Country Status (11)

Country Link
US (1) US8628807B2 (pt)
EP (2) EP1323738A1 (pt)
JP (1) JP4509564B2 (pt)
AT (1) ATE366750T1 (pt)
AU (1) AU2002358351B2 (pt)
BR (1) BRPI0215394B8 (pt)
CA (1) CA2471679A1 (pt)
DE (1) DE60221155T2 (pt)
ES (1) ES2290350T3 (pt)
HR (1) HRP20040586A2 (pt)
WO (1) WO2003055918A1 (pt)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2224881B1 (es) * 2003-08-26 2006-07-16 Universidad De Alcala Procedimiento mejorado para el fraccionamiento de principios activos de hojas de aloe.
GB0426068D0 (en) * 2004-11-29 2004-12-29 Passion For Life Healthcare Lt Composition with bacteria blocking action
US7678886B2 (en) 2005-01-07 2010-03-16 Xencor, Inc. Pharmaceutical compositions of adiponectin variants and methods of storage
NL2001386C2 (nl) * 2008-03-18 2008-11-25 Novaclin B V Huidverzorgingsproduct en gebruik van een copolymeer van galactoarabinaan en polyglucuronzuur voor de vervaardiging daarvan.
CN101392033B (zh) * 2008-11-03 2011-12-21 中国烟草总公司郑州烟草研究院 芦荟多糖提取方法及其在卷烟中的应用
US20140242005A1 (en) 2011-10-05 2014-08-28 Multi Oral Bv Method For Oral Care
US9580758B2 (en) 2013-11-12 2017-02-28 Luc Montagnier System and method for the detection and treatment of infection by a microbial agent associated with HIV infection
US10449143B2 (en) 2014-04-17 2019-10-22 Conopco, Inc. Aloe vera extract for personal care compositions
US10456353B2 (en) 2014-04-17 2019-10-29 Conopco, Inc. Personal care compositions
IT201700122874A1 (it) * 2017-10-31 2019-05-01 Roberto Leone Composizione edibile a base di bava di lumaca per la conservazione degli alimenti e per la sanificazione di superfici, ambienti e strumenti
WO2019124075A1 (ja) 2017-12-19 2019-06-27 森永乳業株式会社 アロエ粉末の製造方法
KR102071668B1 (ko) * 2018-04-04 2020-01-30 주식회사 엘지생활건강 한약재 추출물 또는 이의 분획물을 포함하는 인플루엔자 바이러스 감염의 예방 또는 치료용 조성물
CN111494285A (zh) * 2020-06-04 2020-08-07 珠海萱嘉君行健康产业发展有限公司 一种基于芦荟皮或芦荟废水提取抑菌物质的方法及其应用
WO2022046975A1 (en) * 2020-08-28 2022-03-03 Herbalife International Of America, Inc. Compositions comprising neutral and acidic polysaccharides of aloe vera and their uses
JP2023549288A (ja) 2020-10-21 2023-11-22 2キューアール・リサーチ・ベスローテン・フェンノートシャップ 微生物中和のためのアロエ抽出物
CN113563491A (zh) * 2021-09-01 2021-10-29 重庆化工职业学院 一种芦荟多糖的提取方法
CN116549551B (zh) * 2023-05-24 2025-02-14 海南九面通科技有限公司 芦荟全叶粉或其活性成分在制备治疗慢性萎缩性胃炎药物中的应用

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL297511A (pt) * 1956-12-20
US3360511A (en) * 1966-11-22 1967-12-26 Farkas Alexander Aloe polysaccharide composition and its preparation
ZA793769B (en) * 1978-07-25 1981-02-25 Wellcome Found Pharmaceutical formulation of guar gum
US4861761A (en) * 1984-06-28 1989-08-29 Dr. Madis Laboratories, Inc. Aloeferon isolation, manufacturing and its applications
JPS63501221A (ja) * 1985-06-28 1988-05-12 カ−リントン ラボラトリ−ズ インコ−ポレ−テツド アロエ製品の製造方法、該方法によって得られた製品およびその組成物
US5902796A (en) * 1995-09-22 1999-05-11 Carrington Laboratories, Inc. Bioactive factors of aloe vera plants
JP3677376B2 (ja) * 1996-08-13 2005-07-27 武田薬品工業株式会社 医薬
US5824659A (en) * 1996-09-04 1998-10-20 Board Of Regents, The University Of Texas System Cytoprotective oligosaccharide from Aloe preventing damage to the skin immune system by UV radiation
KR100678238B1 (ko) * 1997-10-10 2007-02-01 유니젠 파아마슈티컬스,인크. 알로에로부터 면역조절성 다당류를 제조하는 방법
US6290964B1 (en) 1998-03-06 2001-09-18 Kathleen Shupe Antimicrobial agents isolated from aloe vera
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Also Published As

Publication number Publication date
EP1323738A1 (en) 2003-07-02
DE60221155T2 (de) 2008-03-20
JP2005524617A (ja) 2005-08-18
EP1461361B1 (en) 2007-07-11
HRP20040586A2 (en) 2005-02-28
BR0215394B1 (pt) 2014-07-22
AU2002358351B2 (en) 2008-06-05
AU2002358351A1 (en) 2003-07-15
EP1461361A1 (en) 2004-09-29
JP4509564B2 (ja) 2010-07-21
US20050019433A1 (en) 2005-01-27
ATE366750T1 (de) 2007-08-15
BR0215394A (pt) 2005-04-05
US8628807B2 (en) 2014-01-14
CA2471679A1 (en) 2003-07-10
ES2290350T3 (es) 2008-02-16
WO2003055918A1 (en) 2003-07-10
DE60221155D1 (de) 2007-08-23

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