BRPI0309631A8 - vacina tetravalente da dengue contendo uma trivial deleção de 30 nucleotídeos na utr-31' dos tipos de dengue 1,2,3 e 4, ou de vírus antigênicos quiméricos da dengue 1,2,3 e 4 - Google Patents

vacina tetravalente da dengue contendo uma trivial deleção de 30 nucleotídeos na utr-31' dos tipos de dengue 1,2,3 e 4, ou de vírus antigênicos quiméricos da dengue 1,2,3 e 4 Download PDF

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Publication number
BRPI0309631A8
BRPI0309631A8 BRPI0309631A BRPI0309631A BRPI0309631A8 BR PI0309631 A8 BRPI0309631 A8 BR PI0309631A8 BR PI0309631 A BRPI0309631 A BR PI0309631A BR PI0309631 A BRPI0309631 A BR PI0309631A BR PI0309631 A8 BRPI0309631 A8 BR PI0309631A8
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BR
Brazil
Prior art keywords
dengue
deletion
utr
trivial
nucleotides
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BRPI0309631A
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English (en)
Inventor
R Murphy Brian
Falgout Barry
Blaney Joseph
Hanley Kathryn
Markoff Lewis
S Whitehead Stephen
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The Government Of The Us Secretary Department Of Health And Human Services
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Application filed by The Government Of The Us Secretary Department Of Health And Human Services filed Critical The Government Of The Us Secretary Department Of Health And Human Services
Publication of BRPI0309631A2 publication Critical patent/BRPI0309631A2/pt
Publication of BRPI0309631A8 publication Critical patent/BRPI0309631A8/pt
Publication of BRPI0309631B1 publication Critical patent/BRPI0309631B1/pt

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5254—Virus avirulent or attenuated
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5256—Virus expressing foreign proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/70—Multivalent vaccine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/24011—Flaviviridae
    • C12N2770/24111—Flavivirus, e.g. yellow fever virus, dengue, JEV
    • C12N2770/24134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/24011—Flaviviridae
    • C12N2770/24111—Flavivirus, e.g. yellow fever virus, dengue, JEV
    • C12N2770/24161—Methods of inactivation or attenuation
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Virology (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Zoology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
BRPI0309631-9A 2002-05-03 2003-04-25 Composição imunogênica tetravalente compreendendo vírus atenuado contra dengue e vacina tetravalente compreendendo a dita composição BRPI0309631B1 (pt)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US37786002P 2002-05-03 2002-05-03
US60/377,860 2002-05-03
US43650002P 2002-12-23 2002-12-23
US60/436,500 2002-12-23
PCT/US2003/013279 WO2003092592A2 (en) 2002-05-03 2003-04-25 Dengue tetravalent vaccine containing a common 30 nucleotide deletion in the 3'-utr of dengue types 1,2,3, and 4, or antigenic chimeric dengue viruses 1,2,3, and 4

Publications (3)

Publication Number Publication Date
BRPI0309631A2 BRPI0309631A2 (pt) 2016-11-01
BRPI0309631A8 true BRPI0309631A8 (pt) 2018-09-25
BRPI0309631B1 BRPI0309631B1 (pt) 2021-07-20

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0309631-9A BRPI0309631B1 (pt) 2002-05-03 2003-04-25 Composição imunogênica tetravalente compreendendo vírus atenuado contra dengue e vacina tetravalente compreendendo a dita composição

Country Status (15)

Country Link
US (7) US7517531B2 (pt)
EP (5) EP1554301B1 (pt)
JP (1) JP4977811B2 (pt)
AT (1) ATE481982T1 (pt)
BR (1) BRPI0309631B1 (pt)
CA (1) CA2483653C (pt)
CY (1) CY1120558T1 (pt)
DE (1) DE60334310D1 (pt)
DK (2) DK2338508T3 (pt)
ES (2) ES2355719T3 (pt)
HU (1) HUE037330T2 (pt)
PT (2) PT2338508T (pt)
SI (2) SI2338508T1 (pt)
TR (1) TR201806655T4 (pt)
WO (1) WO2003092592A2 (pt)

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KR101193186B1 (ko) 2010-02-01 2012-10-19 삼성디스플레이 주식회사 박막 증착 장치, 이를 이용한 유기 발광 디스플레이 장치의 제조방법 및 이에 따라 제조된 유기 발광 디스플레이 장치
KR101156441B1 (ko) 2010-03-11 2012-06-18 삼성모바일디스플레이주식회사 박막 증착 장치
KR101202348B1 (ko) 2010-04-06 2012-11-16 삼성디스플레이 주식회사 박막 증착 장치 및 이를 이용한 유기 발광 표시 장치의 제조 방법
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KR101223723B1 (ko) 2010-07-07 2013-01-18 삼성디스플레이 주식회사 박막 증착 장치, 이를 이용한 유기 발광 디스플레이 장치의 제조방법 및 이에 따라 제조된 유기 발광 디스플레이 장치
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KR101852517B1 (ko) 2011-05-25 2018-04-27 삼성디스플레이 주식회사 유기층 증착 장치 및 이를 이용한 유기 발광 디스플레이 장치의 제조 방법
KR101840654B1 (ko) 2011-05-25 2018-03-22 삼성디스플레이 주식회사 유기층 증착 장치 및 이를 이용한 유기 발광 디스플레이 장치의 제조 방법
KR101857249B1 (ko) 2011-05-27 2018-05-14 삼성디스플레이 주식회사 패터닝 슬릿 시트 어셈블리, 유기막 증착 장치, 유기 발광 표시장치제조 방법 및 유기 발광 표시 장치
KR20130004830A (ko) 2011-07-04 2013-01-14 삼성디스플레이 주식회사 유기층 증착 장치 및 이를 이용한 유기 발광 표시 장치의 제조 방법
KR101826068B1 (ko) 2011-07-04 2018-02-07 삼성디스플레이 주식회사 유기층 증착 장치
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JP2005532044A (ja) 2005-10-27
CA2483653A1 (en) 2003-11-13
US11753627B2 (en) 2023-09-12
WO2003092592A2 (en) 2003-11-13
CY1120558T1 (el) 2019-07-10
EP3205352A1 (en) 2017-08-16
EP3763382A1 (en) 2021-01-13
USRE46631E1 (en) 2017-12-12
DE60334310D1 (de) 2010-11-04
US20090258036A1 (en) 2009-10-15
EP2338508A1 (en) 2011-06-29
US20130011433A1 (en) 2013-01-10
HUE037330T2 (hu) 2018-08-28
DK2338508T3 (en) 2018-05-28
BRPI0309631B1 (pt) 2021-07-20
EP2319532A1 (en) 2011-05-11
US20180010099A1 (en) 2018-01-11
JP4977811B2 (ja) 2012-07-18
BRPI0309631A2 (pt) 2016-11-01
DK1554301T3 (da) 2011-01-24
US20070009552A1 (en) 2007-01-11
US7517531B2 (en) 2009-04-14
AU2003231185A1 (en) 2003-11-17
WO2003092592A3 (en) 2005-05-19
USRE46641E1 (en) 2017-12-19
ES2677348T3 (es) 2018-08-01
US9783787B2 (en) 2017-10-10
SI1554301T1 (sl) 2011-01-31
ATE481982T1 (de) 2010-10-15
US10837003B2 (en) 2020-11-17
EP2338508B1 (en) 2018-02-14
ES2355719T3 (es) 2011-03-30
US20200392469A1 (en) 2020-12-17
PT1554301E (pt) 2010-12-28
PT2338508T (pt) 2018-05-16
SI2338508T1 (en) 2018-07-31
TR201806655T4 (tr) 2018-06-21
CA2483653C (en) 2014-10-28
EP1554301A4 (en) 2006-11-08
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EP1554301A2 (en) 2005-07-20
EP1554301B1 (en) 2010-09-22

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