BRPI0316264B8 - compostos, seu uso e formulação farmacêutica que os contém - Google Patents

compostos, seu uso e formulação farmacêutica que os contém

Info

Publication number
BRPI0316264B8
BRPI0316264B8 BRPI0316264A BR0316264A BRPI0316264B8 BR PI0316264 B8 BRPI0316264 B8 BR PI0316264B8 BR PI0316264 A BRPI0316264 A BR PI0316264A BR 0316264 A BR0316264 A BR 0316264A BR PI0316264 B8 BRPI0316264 B8 BR PI0316264B8
Authority
BR
Brazil
Prior art keywords
compounds
pharmaceutical formulation
formulation containing
pulmonary disease
chronic obstructive
Prior art date
Application number
BRPI0316264A
Other languages
English (en)
Other versions
BRPI0316264B1 (pt
BR0316264A (pt
Inventor
Schnapp Andreas
Hoenke Christoph
Heine Claudia
Buettner Frank
Schollenberger Hermann
Konetzki Ingo
Rudolf Klaus
Schromm Kurt
Lustenberger Philipp
Pestel Sabine
Bouyssou Thierry
Original Assignee
Boehringer Ingelheim Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=32185709&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BRPI0316264(B8) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Boehringer Ingelheim Pharma filed Critical Boehringer Ingelheim Pharma
Publication of BR0316264A publication Critical patent/BR0316264A/pt
Publication of BRPI0316264B1 publication Critical patent/BRPI0316264B1/pt
Publication of BRPI0316264B8 publication Critical patent/BRPI0316264B8/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/538—1,4-Oxazines, e.g. morpholine ortho- or peri-condensed with carbocyclic ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
    • C07D265/34—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings
    • C07D265/36—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings condensed with one six-membered ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

emprego de compostos para preparação de medicamento para tratamento de doença pulmonar obstrutiva crônica, compostos, bem como formulações farmacêuticas que os contém. a presente invenção refere-se ao emprego dos compostos de fórmula geral 1 1 na qual os radicais r1, r2 e r3 podem ter os significados mencionados nas reivindicações e na descrição, para preparação de um medicamento para tratamento de copd (doença pulmonar obstrutiva crônica = chronic obstructive pulmonary disease), assim como a novos compostos de fórmula geral 1 como tal.
BRPI0316264A 2002-11-15 2003-11-11 compostos, seu uso e formulação farmacêutica que os contém BRPI0316264B8 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE10253282A DE10253282A1 (de) 2002-11-15 2002-11-15 Neue Arzneimittel zur Behandlung von chronisch obstruktiver Lungenerkrankung
DE10253282.6 2002-11-15
PCT/EP2003/012565 WO2004045618A2 (de) 2002-11-15 2003-11-11 Neue arzneimittel zur behandlung von chronisch obstruktiver lungenerkrankung

Publications (3)

Publication Number Publication Date
BR0316264A BR0316264A (pt) 2005-10-11
BRPI0316264B1 BRPI0316264B1 (pt) 2019-04-09
BRPI0316264B8 true BRPI0316264B8 (pt) 2021-05-25

Family

ID=32185709

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0316264A BRPI0316264B8 (pt) 2002-11-15 2003-11-11 compostos, seu uso e formulação farmacêutica que os contém

Country Status (38)

Country Link
EP (2) EP2025338A1 (pt)
JP (1) JP4317138B2 (pt)
KR (1) KR101092247B1 (pt)
CN (3) CN101735166A (pt)
AR (2) AR041969A1 (pt)
AT (1) ATE430569T1 (pt)
AU (1) AU2003285326B2 (pt)
BE (1) BE2014C016I2 (pt)
BR (1) BRPI0316264B8 (pt)
CA (1) CA2506082C (pt)
CO (1) CO5570670A2 (pt)
CY (2) CY1110500T1 (pt)
DE (2) DE10253282A1 (pt)
DK (1) DK1562603T3 (pt)
EA (1) EA008665B1 (pt)
EC (1) ECSP055774A (pt)
ES (1) ES2326878T7 (pt)
FR (1) FR14C0049I2 (pt)
HR (1) HRP20050432B1 (pt)
HU (1) HUS1400011I1 (pt)
IL (1) IL167900A (pt)
LT (1) LTC1562603I2 (pt)
LU (1) LU92433I2 (pt)
ME (1) ME00354B (pt)
MX (1) MXPA05005081A (pt)
MY (1) MY136034A (pt)
NL (1) NL300650I2 (pt)
NO (2) NO334314B1 (pt)
NZ (1) NZ540661A (pt)
PE (1) PE20040694A1 (pt)
PL (1) PL212238B1 (pt)
PT (1) PT1562603E (pt)
RS (1) RS51607B (pt)
SI (1) SI1562603T1 (pt)
TW (1) TWI343812B (pt)
UA (1) UA81276C2 (pt)
WO (1) WO2004045618A2 (pt)
ZA (1) ZA200502246B (pt)

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Also Published As

Publication number Publication date
EP1562603B3 (de) 2014-01-08
FR14C0049I1 (pt) 2014-08-08
ATE430569T1 (de) 2009-05-15
EA200500715A1 (ru) 2005-12-29
RS20050361A (sr) 2007-04-10
ES2326878T7 (es) 2014-03-11
CA2506082A1 (en) 2004-06-03
PL375270A1 (en) 2005-11-28
MXPA05005081A (es) 2005-07-01
ZA200502246B (en) 2006-01-25
DE10253282A1 (de) 2004-05-27
EP1562603A2 (de) 2005-08-17
MEP53608A (en) 2011-05-10
ES2326878T3 (es) 2009-10-21
JP4317138B2 (ja) 2009-08-19
DK1562603T3 (da) 2009-09-07
EA008665B1 (ru) 2007-06-29
JP2006508140A (ja) 2006-03-09
BE2014C016I2 (pt) 2023-03-07
HRP20050432B1 (en) 2012-01-31
BRPI0316264B1 (pt) 2019-04-09
PE20040694A1 (es) 2004-11-23
TW200423943A (en) 2004-11-16
NO20052883L (no) 2005-06-14
EP1562603B1 (de) 2009-05-06
KR20050075013A (ko) 2005-07-19
EP2025338A1 (de) 2009-02-18
CN101817800A (zh) 2010-09-01
BR0316264A (pt) 2005-10-11
UA81276C2 (en) 2007-12-25
ME00354B (me) 2011-10-10
FR14C0049I2 (fr) 2015-07-24
CO5570670A2 (es) 2005-10-31
NZ540661A (en) 2007-12-21
CY1110500T1 (el) 2015-04-29
HUS1400011I1 (hu) 2022-02-28
RS51607B (sr) 2011-08-31
AU2003285326B2 (en) 2009-06-04
AR087241A2 (es) 2014-03-12
LU92433I2 (fr) 2014-06-24
WO2004045618A2 (de) 2004-06-03
SI1562603T1 (sl) 2009-10-31
AR041969A1 (es) 2005-06-01
TWI343812B (en) 2011-06-21
CN101735166A (zh) 2010-06-16
AU2003285326A1 (en) 2004-06-15
WO2004045618A3 (de) 2004-09-30
LTC1562603I2 (lt) 2016-12-12
PT1562603E (pt) 2009-06-18
CY2014032I1 (el) 2015-12-09
NO334314B1 (no) 2014-02-03
KR101092247B1 (ko) 2011-12-12
ECSP055774A (es) 2005-11-22
CY2014032I2 (el) 2015-12-09
NO2014005I1 (no) 2014-03-10
DE50311502D1 (de) 2009-06-18
PL212238B1 (pl) 2012-08-31
NL300650I2 (nl) 2017-11-02
CN1713914A (zh) 2005-12-28
IL167900A (en) 2013-06-27
MY136034A (en) 2008-07-31
CA2506082C (en) 2011-06-21
HRP20050432A2 (en) 2006-06-30

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