BRPI0400284A - Uso de dm 43 e seus fragmentos como inibidor de metaloproteases de matriz - Google Patents

Uso de dm 43 e seus fragmentos como inibidor de metaloproteases de matriz

Info

Publication number
BRPI0400284A
BRPI0400284A BR0400284-9A BRPI0400284A BRPI0400284A BR PI0400284 A BRPI0400284 A BR PI0400284A BR PI0400284 A BRPI0400284 A BR PI0400284A BR PI0400284 A BRPI0400284 A BR PI0400284A
Authority
BR
Brazil
Prior art keywords
matrix metalloprotease
metalloprotease inhibitor
fragments
inhibitor
relates
Prior art date
Application number
BR0400284-9A
Other languages
English (en)
Inventor
Patricia Barbosa Jurgilas
Juliana De Meis
Richard Hemmi Valente
Ana Gisele Da Costa N Ferreira
Daniella Areas Mendes Da Cruz
Desio Aurelio Farias Oliveira
Wilson Savino
Gilberto Barbosa Domont
Jonas Enrique Perales Aguilar
Original Assignee
Fundacao Oswaldo Cruz
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fundacao Oswaldo Cruz filed Critical Fundacao Oswaldo Cruz
Priority to BR0400284-9A priority Critical patent/BRPI0400284A/pt
Priority to EP05714403A priority patent/EP1786452A1/en
Priority to PCT/BR2005/000036 priority patent/WO2005087252A1/en
Priority to US10/593,527 priority patent/US20080249005A1/en
Publication of BRPI0400284A publication Critical patent/BRPI0400284A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/55—Protease inhibitors
    • A61K38/57—Protease inhibitors from animals; from humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Epidemiology (AREA)
  • Neurology (AREA)
  • Hospice & Palliative Care (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Psychiatry (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

"USO DE DM43 E SEUS FRAGMENTOS COMO INIBIDOR DE METALOPROTEASES DE MATRIZ". A presente invenção está relacionada ao uso da proteína DM43 como inibidor de metaloproteases. Mais particularmente, a presente invenção está relacionada ao uso de DM43 para terapêutica de patologias como cânceres e osteoartrite, dependentes da inibição de metaloproteases de matriz, baseando-se na identidade estrutural com as SVMPs.
BR0400284-9A 2004-03-18 2004-03-18 Uso de dm 43 e seus fragmentos como inibidor de metaloproteases de matriz BRPI0400284A (pt)

Priority Applications (4)

Application Number Priority Date Filing Date Title
BR0400284-9A BRPI0400284A (pt) 2004-03-18 2004-03-18 Uso de dm 43 e seus fragmentos como inibidor de metaloproteases de matriz
EP05714403A EP1786452A1 (en) 2004-03-18 2005-03-18 Use of dm43 and its fragments as matrix metalloproteinases inhibitor
PCT/BR2005/000036 WO2005087252A1 (en) 2004-03-18 2005-03-18 Use of dm43 and its fragments as matrix metalloproteinases inhibitor
US10/593,527 US20080249005A1 (en) 2004-03-18 2005-03-18 Use of Dm43 and Its Fragments as Matrix Metalloproteinases Inhibitor

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
BR0400284-9A BRPI0400284A (pt) 2004-03-18 2004-03-18 Uso de dm 43 e seus fragmentos como inibidor de metaloproteases de matriz

Publications (1)

Publication Number Publication Date
BRPI0400284A true BRPI0400284A (pt) 2005-11-01

Family

ID=34975334

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0400284-9A BRPI0400284A (pt) 2004-03-18 2004-03-18 Uso de dm 43 e seus fragmentos como inibidor de metaloproteases de matriz

Country Status (4)

Country Link
US (1) US20080249005A1 (pt)
EP (1) EP1786452A1 (pt)
BR (1) BRPI0400284A (pt)
WO (1) WO2005087252A1 (pt)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0642353A1 (en) * 1992-05-14 1995-03-15 Oncologix, Inc. Treatment of vascular leakage syndrome and collagenase induced disease by administration of matrix metalloproteinase inhibitors
IT1277904B1 (it) * 1995-08-07 1997-11-12 Polifarma Spa Metodo per determinare l'attivita' terapeutica di composti inibitori di metalloproteinasi, nuovi composti inibitori, e loro impiego
IT1296305B1 (it) * 1997-07-17 1999-06-25 Polifarma Spa Inibitori di metalloproteinasi loro uso terapeutico e procedimento per la produzione del composto di partenza nella loro
WO2001078894A2 (en) * 2000-04-13 2001-10-25 Schering Corporation Novel human gene relating to respiratory diseases, obesity, and inflammatory bowel disease

Also Published As

Publication number Publication date
EP1786452A1 (en) 2007-05-23
WO2005087252A1 (en) 2005-09-22
US20080249005A1 (en) 2008-10-09

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Legal Events

Date Code Title Description
B03A Publication of a patent application or of a certificate of addition of invention [chapter 3.1 patent gazette]
B11A Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing
B11Y Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette]
B11N Dismissal: publication cancelled [chapter 11.14 patent gazette]

Free format text: REFERENTE A RPI NO 1977 DE 25/11/2008.

B04C Request for examination: application reinstated [chapter 4.3 patent gazette]
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B11B Dismissal acc. art. 36, par 1 of ipl - no reply within 90 days to fullfil the necessary requirements