BRPI0403949A - Forma de dosagem farmacêutica e método para sua produção - Google Patents
Forma de dosagem farmacêutica e método para sua produçãoInfo
- Publication number
- BRPI0403949A BRPI0403949A BR0403949-1A BRPI0403949A BRPI0403949A BR PI0403949 A BRPI0403949 A BR PI0403949A BR PI0403949 A BRPI0403949 A BR PI0403949A BR PI0403949 A BRPI0403949 A BR PI0403949A
- Authority
- BR
- Brazil
- Prior art keywords
- weight
- copolymer
- drug form
- accordance
- active ingredient
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 2
- 239000002552 dosage form Substances 0.000 title 1
- 229920001577 copolymer Polymers 0.000 abstract 4
- 239000003814 drug Substances 0.000 abstract 4
- 229940079593 drug Drugs 0.000 abstract 4
- SOGAXMICEFXMKE-UHFFFAOYSA-N Butylmethacrylate Chemical compound CCCCOC(=O)C(C)=C SOGAXMICEFXMKE-UHFFFAOYSA-N 0.000 abstract 2
- BAPJBEWLBFYGME-UHFFFAOYSA-N Methyl acrylate Chemical compound COC(=O)C=C BAPJBEWLBFYGME-UHFFFAOYSA-N 0.000 abstract 2
- 239000004480 active ingredient Substances 0.000 abstract 2
- 239000011159 matrix material Substances 0.000 abstract 2
- JIGUQPWFLRLWPJ-UHFFFAOYSA-N Ethyl acrylate Chemical compound CCOC(=O)C=C JIGUQPWFLRLWPJ-UHFFFAOYSA-N 0.000 abstract 1
- CERQOIWHTDAKMF-UHFFFAOYSA-N Methacrylic acid Chemical compound CC(=C)C(O)=O CERQOIWHTDAKMF-UHFFFAOYSA-N 0.000 abstract 1
- 239000008186 active pharmaceutical agent Substances 0.000 abstract 1
- 238000005266 casting Methods 0.000 abstract 1
- 238000007906 compression Methods 0.000 abstract 1
- 230000006835 compression Effects 0.000 abstract 1
- 238000007598 dipping method Methods 0.000 abstract 1
- 238000001125 extrusion Methods 0.000 abstract 1
- 230000009477 glass transition Effects 0.000 abstract 1
- 238000001746 injection moulding Methods 0.000 abstract 1
- 238000002844 melting Methods 0.000 abstract 1
- 230000008018 melting Effects 0.000 abstract 1
- 239000000178 monomer Substances 0.000 abstract 1
- PNJWIWWMYCMZRO-UHFFFAOYSA-N pent‐4‐en‐2‐one Natural products CC(=O)CC=C PNJWIWWMYCMZRO-UHFFFAOYSA-N 0.000 abstract 1
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 1
- 238000005507 spraying Methods 0.000 abstract 1
- 238000003892 spreading Methods 0.000 abstract 1
- 238000005550 wet granulation Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
- A61K9/2846—Poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/10—Laxatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Inorganic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Crystals, And After-Treatments Of Crystals (AREA)
- Inorganic Fibers (AREA)
Abstract
"FORMA DE DOSAGEM FARMACêUTICA E MéTODO PARA SUA PRODUçãO". A invenção refere-se a um processo para produzir uma forma de droga revestida ou uma forma de droga na forma de uma matriz de ingrediente ativo, processando um copolímero, um ingrediente farmacêutico ativo, um núcleo se presente e/ou excipientes farmaceuticamente habituais de uma maneira convencional mediante derretimento, moldagem por injeção, extrusão, granulação a úmido, fundição, imersão, esparramamento, pulverização ou compressão para formar uma forma de droga revestida e/ou formar uma matriz de ingrediente ativo, caracterizado pelo fato de que um copolímero é usado que é composto de 20 a 33% em peso de ácido metacrílico, 5 a 30% em peso de acrilato de metila, 20 a 40% em peso de acrilato de etila e mais de 10 a 30% em peso de metacrilato de butila e, se desejado, 0 a 10% em peso de outros monómeros vinilicamente copolimerizáveis, com a condição que a temperatura de transição vítrea do copolímero de acordo com ISO 11357-2, seção 3.3.3, seja 55 a 70<198>C. A invenção também refere-se à forma de droga produzida de acordo com a invenção, ao copolímero e ao uso deste.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE2003119458 DE10319458A1 (de) | 2003-04-29 | 2003-04-29 | Arzneiform und Verfahren zu ihrer Herstellung |
| PCT/EP2004/002061 WO2004096185A1 (de) | 2003-04-29 | 2004-03-02 | Arzneiform und verfahren zu ihrer herstellung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0403949A true BRPI0403949A (pt) | 2005-03-01 |
Family
ID=33305063
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR0403949-1A BRPI0403949A (pt) | 2003-04-29 | 2004-03-02 | Forma de dosagem farmacêutica e método para sua produção |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US7498044B2 (pt) |
| EP (1) | EP1496870B1 (pt) |
| JP (1) | JP4708327B2 (pt) |
| KR (1) | KR101132149B1 (pt) |
| CN (1) | CN1697649B (pt) |
| AT (1) | ATE441405T1 (pt) |
| BR (1) | BRPI0403949A (pt) |
| CA (1) | CA2489064C (pt) |
| DE (2) | DE10319458A1 (pt) |
| ES (1) | ES2331799T3 (pt) |
| IL (1) | IL164518A (pt) |
| MX (1) | MXPA04010956A (pt) |
| PL (1) | PL1496870T3 (pt) |
| SI (1) | SI1496870T1 (pt) |
| WO (1) | WO2004096185A1 (pt) |
Families Citing this family (69)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10220470A1 (de) * | 2002-04-30 | 2003-11-20 | Roehm Gmbh | ph-sensitives Polymer |
| DE19961334A1 (de) * | 1999-12-17 | 2001-06-21 | Roehm Gmbh | Spritzgußverfahren für neutrale und säuregruppenhaltige (Meth)acrylat-Copolymere |
| DE10043868A1 (de) * | 2000-09-04 | 2002-04-04 | Roehm Gmbh | PMMA Formmassen mit verbesserter Schlagzähigkeit |
| DE10127134A1 (de) * | 2001-06-05 | 2002-12-12 | Roehm Gmbh | verfahren zur Herstellung von Formkörpern aus (Meth)acrylat-Copolymeren mittels Spritzguß |
| DE10204890A1 (de) * | 2002-02-06 | 2003-08-14 | Roehm Gmbh | Schlagzähe Formmasse und Formkörper |
| DE10236240A1 (de) * | 2002-02-06 | 2003-08-14 | Roehm Gmbh | Silicon-Pfropfcopolymerisate mit Kern-Hülle-Struktur, schlagzähmodifizierte Formmassen und Formkörper sowie Verfahren zu deren Herstellung |
| DE10260065A1 (de) * | 2002-12-19 | 2004-07-01 | Röhm GmbH & Co. KG | Kern-Schale-Teilchen zur Schlagzähmodifizierung von Poly(meth)acrylat-Formmassen |
| MXPA04010956A (es) | 2003-01-30 | 2005-01-25 | Roehm Gmbh | Forma de dosis farmaceutica y metodo para la produccion de la misma. |
| DE10320318A1 (de) * | 2003-05-06 | 2004-12-02 | Röhm GmbH & Co. KG | Verfahren zur Herstellung von lichtstreuenden Formteilen mit hervorragenden optischen Eigenschaften |
| DE10345045A1 (de) * | 2003-09-26 | 2005-04-14 | Röhm GmbH & Co. KG | Verfahren zur Oberflächenvergütung von Werkstoffen durch Aufbringen insbesondere transparenter Schichten auf Basis von Polymethacrylaten |
| DE10349144A1 (de) * | 2003-10-17 | 2005-05-12 | Roehm Gmbh | Polymermischung für mattierte Spritzgußteile |
| DE10351535A1 (de) | 2003-11-03 | 2005-06-09 | Röhm GmbH & Co. KG | Mehrschichtfolie aus (Meth)acrylatcopolymer und Polycarbonat |
| DE10354379A1 (de) * | 2003-11-20 | 2005-06-23 | Röhm GmbH & Co. KG | Formmasse, enthaltend ein Mattierungsmittel |
| DE102004022540A1 (de) * | 2004-05-05 | 2005-12-08 | Röhm GmbH & Co. KG | Formmasse für Formkörper mit hoher Witterungsbeständigkeit |
| DE102004045296A1 (de) * | 2004-09-16 | 2006-03-23 | Röhm GmbH & Co. KG | Verwendung von Polyalkyl (meth) acrylat-Perlpolymerisaten und Formmasse zur Herstellung von extrudierten Formteilen mit mattierter Oberfläche |
| US9011831B2 (en) * | 2004-09-30 | 2015-04-21 | Advanced Cardiovascular Systems, Inc. | Methacrylate copolymers for medical devices |
| DE102004058083A1 (de) * | 2004-12-01 | 2006-06-08 | Röhm GmbH & Co. KG | Gedeckt eingefärbte, infrarotreflektierende Kunststoffformmasse |
| DE102005002072A1 (de) * | 2005-01-14 | 2006-07-20 | Röhm GmbH & Co. KG | Witterungsstabile Folie zur Gelbeinfärbung retroreflektierender Formkörper |
| DE102005007059A1 (de) * | 2005-02-15 | 2006-08-24 | Röhm GmbH & Co. KG | Teilneutralisiertes anionisches (Meth)acrylat-Copolymer |
| CA2603405C (en) | 2005-04-18 | 2013-10-01 | Roehm Gmbh | Thermoplastic molding material and molding elements containing nanometric inorganic particles for making said molding material and said molding elements, and uses thereof |
| KR20080028361A (ko) * | 2005-05-03 | 2008-03-31 | 뮤추얼 파마슈티컬 컴퍼니 아이엔씨. | 퀴닌-함유 제어-방출형 제제 |
| DE102005021335A1 (de) * | 2005-05-04 | 2006-11-09 | Röhm Gmbh | Verfahren zur Herstellung von Perlpolymerisaten mit einer mittleren Teilchengröße im Bereich von 1 µm bis 40 µm sowie Perlpolymerisat aufweisende Formmassen und Formkörper |
| DE102005024614A1 (de) * | 2005-05-25 | 2006-11-30 | Röhm Gmbh | Verwendung von Polymermischungen zur Herstellung von überzogenen Arzneiformen sowie Arzneiform mit polymerem Mischüberzug |
| DE102005055793A1 (de) | 2005-11-21 | 2007-05-24 | Röhm Gmbh | Transparente TPU (thermoplastische Polyurethane)/ PMMA (Polymethyl(meth)acrylat) Abmischungen mit verbesserter Kältesschlagzähigkeit |
| EP1825848A3 (de) * | 2006-02-10 | 2010-03-03 | Stada Arzneimittel Ag | Stabile pharmazeutische Zusammensetzungen umfassend einen HMG-CoA-Reduktase Inhibitor |
| ITMI20061024A1 (it) | 2006-05-25 | 2007-11-26 | Eurand Pharmaceuticals Ltd | Pellet a base di acido lipoico |
| DE102006029613A1 (de) * | 2006-06-26 | 2007-12-27 | Röhm Gmbh | Transparenter Kunststoff-Verbund |
| DE102006035549A1 (de) | 2006-07-27 | 2008-01-31 | Evonik Röhm Gmbh | Arzneiform mit mindestens zweischichtiger Trennschicht |
| CN100448432C (zh) * | 2006-10-26 | 2009-01-07 | 徐竹青 | 高溶出度尼莫地平分散片的制备方法 |
| DE102007005432A1 (de) * | 2007-01-30 | 2008-07-31 | Evonik Röhm Gmbh | Formmassen für mattierte Polyacrylat-Formkörper |
| DE102007009243A1 (de) | 2007-02-22 | 2008-09-18 | Evonik Röhm Gmbh | Pellets mit einer Wirkstoff-Matrix und einem Polymerüberzug, sowie ein Verfahren zur Herstellung der Pellets |
| DE102007009242A1 (de) | 2007-02-22 | 2008-09-18 | Evonik Röhm Gmbh | Pellets mit magensaftresistenter Wirkstoff-Matix |
| CN100465201C (zh) * | 2007-04-25 | 2009-03-04 | 上海大学 | 用作药物肠溶包衣材料的水溶性丙烯酸系树脂乳液的制备方法 |
| DE102007026200A1 (de) * | 2007-06-04 | 2008-12-11 | Evonik Röhm Gmbh | Zusammensetzung mit erhöhter Spannungsrissbeständigkeit |
| DE102007026201A1 (de) * | 2007-06-04 | 2008-12-11 | Evonik Röhm Gmbh | Eingefärbte Zusammensetzung mit erhöhter Spannungsrissbeständigkeit |
| DE102007028601A1 (de) * | 2007-06-19 | 2008-12-24 | Evonik Röhm Gmbh | Reaktivgemisch zur Beschichtung von Formkörpern mittels Reaktionsspritzguss sowie beschichteter Formkörper |
| DE102007029263A1 (de) * | 2007-06-22 | 2008-12-24 | Evonik Röhm Gmbh | PMMA/PVDF-Folie mit besonders hoher Witterungsbeständigkeit und hoher UV-Schutzwirkung |
| US20090036414A1 (en) * | 2007-08-02 | 2009-02-05 | Mutual Pharmaceutical Company, Inc. | Mesalamine Formulations |
| DE102007051482A1 (de) * | 2007-10-25 | 2009-04-30 | Evonik Röhm Gmbh | Verfahren zur Herstellung von beschichteten Formkörpern |
| CA2711475A1 (en) * | 2008-01-10 | 2009-07-16 | Evonik Roehm Gmbh | Coated pharmaceutical or nutraceutical preparation with accelerated controlled active substance release |
| BRPI0822026B8 (pt) * | 2008-01-10 | 2021-05-25 | Evonik Roehm Gmbh | preparação farmacêutica ou nutracêutica, comprimido, gelatina ou cápsula de hpmc, e uso de uma ou uma mistura de uma pluralidade de polímeros ou copolímeros |
| EP2254556A2 (en) * | 2008-03-11 | 2010-12-01 | Takeda Pharmaceutical Company Limited | Orally-disintegrating solid preparation |
| DE102008001231A1 (de) * | 2008-04-17 | 2009-10-22 | Evonik Röhm Gmbh | Flammfeste PMMA-Formmasse |
| DE102008001695A1 (de) * | 2008-05-09 | 2009-11-12 | Evonik Röhm Gmbh | Poly(meth)acrylimide mit verbesserten optischen und Farbeigenschaften, insbesondere bei thermischer Belastung |
| EP2564839B1 (en) | 2009-01-09 | 2016-05-11 | Forward Pharma A/S | Pharmaceutical formulation comprising one or more fumaric acid esters in an erosion matrix |
| DE102009028076A1 (de) | 2009-07-29 | 2011-02-03 | Evonik Röhm Gmbh | Beschichtungsmittel zum Tauchbeschichten von Kapselhälften |
| US9107451B2 (en) | 2009-07-29 | 2015-08-18 | Evonik Röhm Gmbh | Coating composition for the dip coating of capsule halves |
| US20110150986A1 (en) * | 2009-12-18 | 2011-06-23 | Kristin Arnold | Quinine formulations, method of making, and metho of use thereof |
| MX346316B (es) | 2010-02-25 | 2017-03-15 | Evonik Roehm Gmbh | Formulacion farmaceutica o nutraceutica. |
| CN101961324A (zh) * | 2010-09-10 | 2011-02-02 | 武汉药谷生物工程有限公司 | 一种依托贝特缓释胶囊的处方及制备方法 |
| MX353426B (es) | 2011-06-17 | 2018-01-12 | Evonik Roehm Gmbh | Composicion de recubrimiento apropiada para formas de dosificacion farmaceuticas o nutraceuticas. |
| EP2720682B1 (en) | 2011-06-17 | 2016-11-23 | Evonik Röhm GmbH | Coating composition suitable for pharmaceutical or nutraceutical dosage forms |
| WO2012171884A1 (en) * | 2011-06-17 | 2012-12-20 | Evonik Röhm Gmbh | Gastric resistant pharmaceutical or nutraceutical composition with resistance against the influence of ethanol |
| US10653631B2 (en) | 2011-09-07 | 2020-05-19 | Roland SAUR-BROSCH | Optimal colon targeting technology |
| US10799460B2 (en) | 2011-09-07 | 2020-10-13 | Roland SAUR-BROSCH | Formulation for the controlled release of one or several substances in the digestive tract of a mammal |
| AU2012345659B2 (en) * | 2011-12-02 | 2017-09-28 | Synchroneuron Inc. | Acamprosate formulations, methods of using the same, and combinations comprising the same |
| CN103385859A (zh) * | 2012-05-08 | 2013-11-13 | 中国人民解放军成都军区总医院 | 一种治疗创伤后应激障碍症的盐酸普萘洛尔口腔崩解片及其制备方法 |
| CN102919661A (zh) * | 2012-10-26 | 2013-02-13 | 广西崇左市湘桂糖业有限公司 | 艾草红糖保健品及其生产方法 |
| FR3007290B1 (fr) * | 2013-06-25 | 2015-06-26 | Expressions Aromatiques | Procede de fabrication de granules contenant un principe actif, a dluo et charge en principe actif optimisees |
| KR101951172B1 (ko) | 2014-11-07 | 2019-02-22 | 주식회사 파나진 | 인유두종바이러스의 유전자형 검출을 위한 ρνα 프로브, 키트 및 방법 |
| US9937223B2 (en) | 2015-01-30 | 2018-04-10 | Par Pharmaceutical, Inc. | Vasopressin formulations for use in treatment of hypotension |
| US9925233B2 (en) | 2015-01-30 | 2018-03-27 | Par Pharmaceutical, Inc. | Vasopressin formulations for use in treatment of hypotension |
| US9375478B1 (en) | 2015-01-30 | 2016-06-28 | Par Pharmaceutical, Inc. | Vasopressin formulations for use in treatment of hypotension |
| US9687526B2 (en) | 2015-01-30 | 2017-06-27 | Par Pharmaceutical, Inc. | Vasopressin formulations for use in treatment of hypotension |
| US9744209B2 (en) | 2015-01-30 | 2017-08-29 | Par Pharmaceutical, Inc. | Vasopressin formulations for use in treatment of hypotension |
| US9750785B2 (en) | 2015-01-30 | 2017-09-05 | Par Pharmaceutical, Inc. | Vasopressin formulations for use in treatment of hypotension |
| EP3653203A4 (en) | 2017-07-11 | 2020-06-24 | Qualicaps Co., Ltd. | ENTERAL HARD CAPSULE |
| KR20210022716A (ko) | 2018-06-22 | 2021-03-03 | 쿠오리카프스 가부시키가이샤 | 장용성 경질 캡슐 |
| US20250064748A1 (en) * | 2022-01-13 | 2025-02-27 | Verily Life Sciences Llc | Drug delivery vehicles, methods of producing drug delivery vehicles, and methods of using drug delivery vehicles |
Family Cites Families (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5292522A (en) * | 1989-06-20 | 1994-03-08 | Rohm Gmbh | Aqueous film coating agent for solid medicaments |
| DE4402666A1 (de) | 1994-01-29 | 1995-08-03 | Roehm Gmbh | Verfahren zum kurzzeitigen Behandeln einer Kunststoffschmelze mit einem flüssigen Behandlungsmittel und dabei hergestellter thermoplastischer Kunststoff |
| DE9414066U1 (de) | 1994-08-31 | 1994-11-03 | Röhm GmbH & Co. KG, 64293 Darmstadt | Überzugs- und Bindemittel für Arzneiformen sowie damit hergestellte Arzneiform |
| DE9414065U1 (de) | 1994-08-31 | 1994-11-03 | Röhm GmbH & Co. KG, 64293 Darmstadt | Thermoplastischer Kunststoff für darmsaftlösliche Arznei-Umhüllungen |
| DE19544562B4 (de) | 1995-11-30 | 2004-05-27 | Röhm GmbH & Co. KG | Verfahren zur Herstellung von Poly(meth)acrylimiden mit bei thermischer Belastung verbesserter Farbstabilität und daraus erhältliche Formkörper |
| DE19653605C2 (de) | 1996-12-20 | 2002-11-28 | Roehm Gmbh | Haft- und Bindemittel für dermale oder transdermale Therapiesysteme und dessen Verwendung zur Herstellung eines transdermalen Therapiesystems |
| DE19653606A1 (de) * | 1996-12-20 | 1998-06-25 | Roehm Gmbh | Haft- und Bindemittel aus (Meth)acrylatpolymer, organischer Säure und Weichmacher |
| DE19718597C1 (de) | 1997-05-02 | 1999-01-07 | Roehm Gmbh | Zweistufiges Verfahren zur Entwässerung von Kunststoffdispersionen |
| MXPA01002779A (es) | 1998-09-18 | 2002-04-08 | Roehm Gmbh | Herramienta de moldeo para piezas brutas de discos portadores de informacion. |
| DE19845358A1 (de) | 1998-10-02 | 2000-04-06 | Roehm Gmbh | Überzogene Arzneiformen mit kontrollierter Wirkstoffabgabe |
| DE10220470A1 (de) | 2002-04-30 | 2003-11-20 | Roehm Gmbh | ph-sensitives Polymer |
| DE19958007A1 (de) | 1999-12-02 | 2001-06-07 | Roehm Gmbh | Spritzgußverfahren für (Meth)acrylat-Copolymere mit teritiären Ammoniumgruppen |
| DE19961334A1 (de) | 1999-12-17 | 2001-06-21 | Roehm Gmbh | Spritzgußverfahren für neutrale und säuregruppenhaltige (Meth)acrylat-Copolymere |
| DE10011447A1 (de) | 2000-03-10 | 2001-09-20 | Roehm Gmbh | Dispersion mit nichtionischem Emulgator |
| DE10013030A1 (de) | 2000-03-17 | 2001-09-20 | Roehm Gmbh | Verwendung eines Copolymers zur Herstellung einer Arzneiform zur Therapie von Colitis ulcerosa und verwendungsgemäße Arzneiform |
| DE10013029A1 (de) | 2000-03-17 | 2001-09-20 | Roehm Gmbh | Mehrschichtige Arzneiform für die Colonfreigabe |
| DE10065492A1 (de) | 2000-12-28 | 2003-06-26 | Roehm Gmbh | Diffus ausgestattete Formmassen und hieraus erhältliche Formkörper |
| JP2004517157A (ja) | 2001-01-29 | 2004-06-10 | レーム ゲゼルシヤフト ミツト ベシユレンクテル ハフツング ウント コンパニー コマンディートゲゼルシャフト | 薬学的適用のための貯蔵安定性接着および結合剤 |
| JP5502254B2 (ja) | 2001-01-31 | 2014-05-28 | エボニック レーム ゲゼルシャフト ミット ベシュレンクテル ハフツング | 少なくとも2種類の異なる被覆ペレット形から成る多粒子剤形 |
| DE10127134A1 (de) | 2001-06-05 | 2002-12-12 | Roehm Gmbh | verfahren zur Herstellung von Formkörpern aus (Meth)acrylat-Copolymeren mittels Spritzguß |
| CN1156500C (zh) * | 2001-07-02 | 2004-07-07 | 山东轻工业学院 | 胃崩型水性药物薄膜包衣材料的制备方法 |
| CA2460132A1 (en) | 2001-10-15 | 2003-04-24 | Roehm Gmbh & Co. Kg | Use of a copolymer to produce a galenic form containing a peptide or a protein as active agent |
| DE10208335A1 (de) * | 2002-02-27 | 2003-09-04 | Roehm Gmbh | Arzneiform und Verfahren zu ihrer Herstellung |
| DE10214002A1 (de) | 2002-03-27 | 2003-10-09 | Roehm Gmbh | Pharmazeutische Formulierung für den Wirkstoff Budesonid |
| MXPA04010956A (es) | 2003-01-30 | 2005-01-25 | Roehm Gmbh | Forma de dosis farmaceutica y metodo para la produccion de la misma. |
-
2003
- 2003-01-30 MX MXPA04010956A patent/MXPA04010956A/es active IP Right Grant
- 2003-04-29 DE DE2003119458 patent/DE10319458A1/de not_active Withdrawn
-
2004
- 2004-03-02 EP EP04716230A patent/EP1496870B1/de not_active Expired - Lifetime
- 2004-03-02 JP JP2006504498A patent/JP4708327B2/ja not_active Expired - Fee Related
- 2004-03-02 AT AT04716230T patent/ATE441405T1/de active
- 2004-03-02 ES ES04716230T patent/ES2331799T3/es not_active Expired - Lifetime
- 2004-03-02 KR KR1020047021295A patent/KR101132149B1/ko not_active Expired - Fee Related
- 2004-03-02 WO PCT/EP2004/002061 patent/WO2004096185A1/de not_active Ceased
- 2004-03-02 US US10/512,860 patent/US7498044B2/en not_active Expired - Lifetime
- 2004-03-02 SI SI200431287T patent/SI1496870T1/sl unknown
- 2004-03-02 CA CA2489064A patent/CA2489064C/en not_active Expired - Lifetime
- 2004-03-02 BR BR0403949-1A patent/BRPI0403949A/pt not_active IP Right Cessation
- 2004-03-02 PL PL04716230T patent/PL1496870T3/pl unknown
- 2004-03-02 DE DE502004009994T patent/DE502004009994D1/de not_active Expired - Lifetime
- 2004-03-02 IL IL164518A patent/IL164518A/en not_active IP Right Cessation
- 2004-03-02 CN CN2004800002764A patent/CN1697649B/zh not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| IL164518A (en) | 2009-05-04 |
| CA2489064C (en) | 2012-10-02 |
| CA2489064A1 (en) | 2004-11-11 |
| JP2006524643A (ja) | 2006-11-02 |
| US20050152977A1 (en) | 2005-07-14 |
| WO2004096185A1 (de) | 2004-11-11 |
| ES2331799T3 (es) | 2010-01-15 |
| DE502004009994D1 (de) | 2009-10-15 |
| KR101132149B1 (ko) | 2012-04-03 |
| IL164518A0 (en) | 2005-12-18 |
| KR20060012544A (ko) | 2006-02-08 |
| PL1496870T3 (pl) | 2010-02-26 |
| EP1496870A1 (de) | 2005-01-19 |
| JP4708327B2 (ja) | 2011-06-22 |
| DE10319458A1 (de) | 2004-11-18 |
| ATE441405T1 (de) | 2009-09-15 |
| CN1697649B (zh) | 2010-05-12 |
| EP1496870B1 (de) | 2009-09-02 |
| US7498044B2 (en) | 2009-03-03 |
| SI1496870T1 (sl) | 2010-01-29 |
| CN1697649A (zh) | 2005-11-16 |
| MXPA04010956A (es) | 2005-01-25 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| IL164518A0 (en) | Pharmaceutical dosage from and method for production thereof | |
| ATE336232T1 (de) | Arzneiform und verfahren ihrer herstellung | |
| ES2307489T5 (es) | Composiciones farmacéuticas sólidas de liberación prolongada obtenidas por termoformación. | |
| EA200900264A1 (ru) | Композиции флибансерина и способ их приготовления | |
| BRPI0812064B8 (pt) | formulação farmacêutica na forma de aglomerados, comprimidos, e, processo para a produção de uma formulação farmacêutica | |
| ATE522200T1 (de) | Aripiprazole injektionsuspension | |
| BRPI0707044B8 (pt) | comprimido matricial insolúvel em água e processo de fabricação de comprimidos matriciais | |
| EA201892836A1 (ru) | Составы 2-[3-[4-амино-3-(2-фтор-4-феноксифенил)пиразол[3,4-d]пиримидин-1-ил]пиперидин-1-карбонил]-4-метил-4-[4-(оксетан-3-ил)пиперазин-1-ил]пент-2-еннитрила с модифицированным высвобождением | |
| BR9808429A (pt) | Composição farmacêutica e processo para a sua preparação. | |
| WO2004062577A3 (en) | Two or more enteric materials to regulate drug release | |
| BRPI0414254A (pt) | composição farmacêutica, e, métodos para fabricar uma composição farmacêutica, para o tratamento de pelo menos uma doença e para controlar a taxa de dissolução de uma formulação | |
| DE50310448D1 (de) | Mehrschichtige wirkstoffhaltige arzneiformen, die einen neutralen kern sowie einen inneren und äusseren überzug aus methacrylat-copolymeren und -monomeren umfassen | |
| WO2007000778A3 (en) | Modified release pharmaceutical compositions on the basis of two polymers and processes thereof | |
| TW200635617A (en) | Multiparticulate pharmaceutical form comprising mucoadhesively formulated nucleic acid active ingredients, and a process for producing the pharmaceutical form | |
| NZ597317A (en) | Solid pharmaceutical fixed dose compositions comprising irbesartan and amlodipine, their preparation and their therapeutic application | |
| WO2004032845A3 (en) | R-nsaid esters and their use | |
| DE50307321D1 (de) | Schmelzextrusion von wirkstoffsalzen | |
| JP2006524643A5 (pt) | ||
| FI3769765T3 (fi) | Natriumalkyylisulfaattia sisältävä farmaseuttinen koostumus | |
| DE60235648D1 (de) | Pharmazeutische metformintablette mit verlängerter freisetzung | |
| HRP20161429T1 (hr) | Farmaceutski sastav | |
| NO20060445L (no) | Fast farmasoytisk preparat omfattende amisulprid | |
| HRP20130108T1 (hr) | Farmaceutski sastav koji sadrži aleglitazar | |
| MXPA05008843A (es) | Sistema terapeutico que comprende amoxicilina y acido clavulanico. | |
| CA2566931A1 (en) | Tablets exhibiting reduced drug release variability |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B25D | Requested change of name of applicant approved |
Owner name: ROEHM GMBH (DE) Free format text: NOME ALTERADO DE: ROEEHM GMBH AND CO. KG |
|
| B25D | Requested change of name of applicant approved |
Owner name: EVONIK ROEHM GMBH (DE) Free format text: NOME ALTERADO DE: ROEHM GMBH |
|
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 12A ANUIDADE. |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2366 DE 10-05-2016 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013. |