BRPI0406824A - Indolonaoxazoldinonas antiibacterianas, intermediários para seu preparo e composições farmacêuticas que as contêm - Google Patents

Indolonaoxazoldinonas antiibacterianas, intermediários para seu preparo e composições farmacêuticas que as contêm

Info

Publication number
BRPI0406824A
BRPI0406824A BR0406824-6A BRPI0406824A BRPI0406824A BR PI0406824 A BRPI0406824 A BR PI0406824A BR PI0406824 A BRPI0406824 A BR PI0406824A BR PI0406824 A BRPI0406824 A BR PI0406824A
Authority
BR
Brazil
Prior art keywords
preparation
antibacterial
intermediates
pharmaceutical compositions
compositions containing
Prior art date
Application number
BR0406824-6A
Other languages
English (en)
Inventor
Toni-Jo Poel
Original Assignee
Pharmacia & Upjohn Co Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia & Upjohn Co Llc filed Critical Pharmacia & Upjohn Co Llc
Publication of BRPI0406824A publication Critical patent/BRPI0406824A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/32—Oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Indole Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

"INDOLONAOXAZOLIDINONAS ANTIBACTERIANAS, INTERMEDIáRIOS PARA SEU PREPARO E COMPOSIçõES FARMACêUTICAS QUE AS CONTêM". A presente invenção proporciona agentes antibacterianos de fórmula (I) e intermediários para a sua preparação.
BR0406824-6A 2003-02-24 2004-02-12 Indolonaoxazoldinonas antiibacterianas, intermediários para seu preparo e composições farmacêuticas que as contêm BRPI0406824A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US44973403P 2003-02-24 2003-02-24
PCT/IB2004/000466 WO2004074282A1 (en) 2003-02-24 2004-02-12 Antibacterial indolone oxazolidinones, intermediates for their preparation and pharmaceutical compositions containing them

Publications (1)

Publication Number Publication Date
BRPI0406824A true BRPI0406824A (pt) 2005-12-27

Family

ID=32908714

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0406824-6A BRPI0406824A (pt) 2003-02-24 2004-02-12 Indolonaoxazoldinonas antiibacterianas, intermediários para seu preparo e composições farmacêuticas que as contêm

Country Status (26)

Country Link
US (1) US7012088B2 (pt)
EP (1) EP1599470A1 (pt)
JP (1) JP3887396B2 (pt)
KR (1) KR100701226B1 (pt)
CN (1) CN100349892C (pt)
AP (1) AP2005003375A0 (pt)
AU (1) AU2004213246A1 (pt)
BR (1) BRPI0406824A (pt)
CA (1) CA2515984A1 (pt)
CO (1) CO5601039A2 (pt)
CR (1) CR7956A (pt)
EA (1) EA009725B1 (pt)
EC (1) ECSP055980A (pt)
GE (1) GEP20084306B (pt)
HR (1) HRP20050658A2 (pt)
IS (1) IS7883A (pt)
MA (1) MA27661A1 (pt)
MX (1) MXPA05008960A (pt)
NO (1) NO20052794L (pt)
OA (1) OA13032A (pt)
PL (1) PL377428A1 (pt)
RS (1) RS20050649A (pt)
TN (1) TNSN05202A1 (pt)
UA (1) UA80326C2 (pt)
WO (1) WO2004074282A1 (pt)
ZA (1) ZA200505225B (pt)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7141588B2 (en) * 2002-02-25 2006-11-28 Pfizer, Inc. N-aryl-2-oxazolidinone-5-carboxamides and their derivatives
EP1781642A1 (en) * 2004-08-06 2007-05-09 Pharmacia & Upjohn Company LLC Oxazolidinones containing oxindoles as antibacterial agents
EP1869029A1 (en) * 2005-04-06 2007-12-26 Pharmacia & Upjohn Company LLC An oxindole oxazolidinone as antibacterial agent
AU2006231919A1 (en) * 2005-04-06 2006-10-12 Pharmacia & Upjohn Company Llc 7-fluoro-1,3-dihydro-indol-2-one oxazolidinones as antibacterial agents
ES2600460T3 (es) 2005-05-10 2017-02-09 Intermune, Inc. Derivados de piridona-2-ona como moduladores del sistema de proteína cinasa activada por estrés
WO2007088478A1 (en) * 2006-02-01 2007-08-09 Pfizer Products Inc. Indazole oxazolidinones as antibacterial agents
EP2004640A1 (en) * 2006-02-08 2008-12-24 Pfizer Products Inc. Oxazolidinones containing oxindoles as antibacterial agents
CN102099036B (zh) 2008-06-03 2015-05-27 英特芒尼公司 用于治疗炎性疾患和纤维化疾患的化合物和方法
FR2948940B1 (fr) * 2009-08-04 2011-07-22 Servier Lab Nouveaux derives dihydroindolones, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
JP5685384B2 (ja) * 2010-03-29 2015-03-18 公益財団法人相模中央化学研究所 ３，３−ジフルオロ−２，３−ジヒドロインドール−２−オン誘導体の製造方法
AR092742A1 (es) 2012-10-02 2015-04-29 Intermune Inc Piridinonas antifibroticas
JP6263124B2 (ja) * 2012-10-17 2018-01-17 国立大学法人 岡山大学 化合物、その互変異性体、幾何異性体、乃至それらの塩、及びそれらの製造方法、抗菌剤、並びに感染症治療薬
CN103193794B (zh) * 2013-04-12 2016-04-06 中国药科大学 一种异吲哚酮并异噁唑类稠环化合物及其合成方法
MX382781B (es) 2014-04-02 2025-03-13 Intermune Inc Piridinonas anti-fibroticas.
CN107151225B (zh) * 2017-06-30 2020-05-08 贵州大学 2-羟基吲哚类衍生物、其制备方法和用途
CN113773306B (zh) * 2021-10-29 2023-11-10 四川农业大学 3,3-二取代吲哚酮类化合物及其制备方法和应用

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5164510A (en) * 1988-09-15 1992-11-17 The Upjohn Company 5'Indolinyl-5β-amidomethyloxazolidin-2-ones
JP2865211B2 (ja) 1988-09-15 1999-03-08 ファルマシア・アンド・アップジョン・カンパニー ５’―インドリニル―５β―アミドメチルオキサゾリジン―２―オン類、３―（縮合環置換）フェニル―５β―アミドメチルオキサゾリジン―２―オン類および３―（窒素原子置換）フェニル―５β―アミドメチルオキサゾリジン―２―オン類
US5225565A (en) * 1988-09-15 1993-07-06 The Upjohn Company Antibacterial 3-(fused-ring substituted)phenyl-5β-amidomethyloxazolidin-2-ones
MY115155A (en) 1993-09-09 2003-04-30 Upjohn Co Substituted oxazine and thiazine oxazolidinone antimicrobials.
DE19514313A1 (de) * 1994-08-03 1996-02-08 Bayer Ag Benzoxazolyl- und Benzothiazolyloxazolidinone
HRP960159A2 (en) * 1995-04-21 1997-08-31 Bayer Ag Benzocyclopentane oxazolidinones containing heteroatoms
DE19601627A1 (de) * 1996-01-18 1997-07-24 Bayer Ag Heteroatomhaltige Cyclopentanopyridyl-Oxazolidinone
DE19604223A1 (de) * 1996-02-06 1997-08-07 Bayer Ag Neue substituierte Oxazolidinone
DE19805117A1 (de) 1998-02-09 1999-08-12 Bayer Ag Neue Oxazolidinone mit azolhaltigen Tricyclen
GB9812019D0 (en) 1998-06-05 1998-07-29 Zeneca Ltd Chemical compounds
WO1999064417A2 (en) 1998-06-05 1999-12-16 Astrazeneca Ab Oxazolidinone derivatives, process for their preparation and pharmaceutical compositions containing them
GB9821938D0 (en) 1998-10-09 1998-12-02 Zeneca Ltd Chemical compounds
WO2000029409A1 (de) 1998-11-17 2000-05-25 Bayer Aktiengesellschaft Neue heterocyclyl-substituierte oxazolidon-derivate
DE19962924A1 (de) 1999-12-24 2001-07-05 Bayer Ag Substituierte Oxazolidinone und ihre Verwendung
PE20011124A1 (es) 2000-03-31 2001-10-28 Upjohn Co Nuevos agentes antibacterianos de benzosultam oxazolidinona
GB0009803D0 (en) 2000-04-25 2000-06-07 Astrazeneca Ab Chemical compounds
US8048386B2 (en) 2002-02-25 2011-11-01 Cepheid Fluid processing and control
PE20030044A1 (es) 2000-11-17 2003-02-09 Upjohn Co Isoxazolinonas biciclicas de formula i
EP1443930A1 (en) 2001-10-25 2004-08-11 AstraZeneca AB Isoxazoline derivatives useful as antimicrobials

Also Published As

Publication number Publication date
TNSN05202A1 (fr) 2007-06-11
JP2006515012A (ja) 2006-05-18
HK1082253A1 (zh) 2006-06-02
GEP20084306B (en) 2008-02-11
CO5601039A2 (es) 2006-01-31
EA200501341A1 (ru) 2006-02-24
US7012088B2 (en) 2006-03-14
EP1599470A1 (en) 2005-11-30
WO2004074282A1 (en) 2004-09-02
KR100701226B1 (ko) 2007-03-29
AU2004213246A1 (en) 2004-09-02
ECSP055980A (es) 2006-01-16
HRP20050658A2 (en) 2005-12-31
UA80326C2 (en) 2007-09-10
IS7883A (is) 2005-06-09
CN1742008A (zh) 2006-03-01
OA13032A (en) 2006-11-10
CR7956A (es) 2005-12-01
AP2005003375A0 (en) 2005-09-30
ZA200505225B (en) 2006-11-29
NO20052794L (no) 2005-11-01
JP3887396B2 (ja) 2007-02-28
PL377428A1 (pl) 2006-02-06
EA009725B1 (ru) 2008-02-28
CN100349892C (zh) 2007-11-21
MA27661A1 (fr) 2005-12-01
MXPA05008960A (es) 2005-11-04
RS20050649A (sr) 2007-11-15
KR20050102135A (ko) 2005-10-25
CA2515984A1 (en) 2004-09-02
NO20052794D0 (no) 2005-06-09
US20040176610A1 (en) 2004-09-09

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE AS 6A, 7A E 8A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2159 DE 22/05/2012.