OA13032A - Antbacterial indolone oxazolidinones, intermediates for their preparation and pharmaceutical compositions containing them. - Google Patents
Antbacterial indolone oxazolidinones, intermediates for their preparation and pharmaceutical compositions containing them. Download PDFInfo
- Publication number
- OA13032A OA13032A OA1200500233A OA1200500233A OA13032A OA 13032 A OA13032 A OA 13032A OA 1200500233 A OA1200500233 A OA 1200500233A OA 1200500233 A OA1200500233 A OA 1200500233A OA 13032 A OA13032 A OA 13032A
- Authority
- OA
- OAPI
- Prior art keywords
- oxo
- indol
- dihydro
- difluoro
- methyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/32—Oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Pharmacology & Pharmacy (AREA)
- Communicable Diseases (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Indole Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US44973403P | 2003-02-24 | 2003-02-24 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| OA13032A true OA13032A (en) | 2006-11-10 |
Family
ID=32908714
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| OA1200500233A OA13032A (en) | 2003-02-24 | 2004-02-12 | Antbacterial indolone oxazolidinones, intermediates for their preparation and pharmaceutical compositions containing them. |
Country Status (26)
| Country | Link |
|---|---|
| US (1) | US7012088B2 (pt) |
| EP (1) | EP1599470A1 (pt) |
| JP (1) | JP3887396B2 (pt) |
| KR (1) | KR100701226B1 (pt) |
| CN (1) | CN100349892C (pt) |
| AP (1) | AP2005003375A0 (pt) |
| AU (1) | AU2004213246A1 (pt) |
| BR (1) | BRPI0406824A (pt) |
| CA (1) | CA2515984A1 (pt) |
| CO (1) | CO5601039A2 (pt) |
| CR (1) | CR7956A (pt) |
| EA (1) | EA009725B1 (pt) |
| EC (1) | ECSP055980A (pt) |
| GE (1) | GEP20084306B (pt) |
| HR (1) | HRP20050658A2 (pt) |
| IS (1) | IS7883A (pt) |
| MA (1) | MA27661A1 (pt) |
| MX (1) | MXPA05008960A (pt) |
| NO (1) | NO20052794L (pt) |
| OA (1) | OA13032A (pt) |
| PL (1) | PL377428A1 (pt) |
| RS (1) | RS20050649A (pt) |
| TN (1) | TNSN05202A1 (pt) |
| UA (1) | UA80326C2 (pt) |
| WO (1) | WO2004074282A1 (pt) |
| ZA (1) | ZA200505225B (pt) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7141588B2 (en) * | 2002-02-25 | 2006-11-28 | Pfizer, Inc. | N-aryl-2-oxazolidinone-5-carboxamides and their derivatives |
| US20080262056A1 (en) * | 2004-08-06 | 2008-10-23 | Pfizer Inc | Oxindole Oxazolidinones as Antibacterial Agents |
| EA200701895A1 (ru) * | 2005-04-06 | 2008-04-28 | ФАРМАЦИЯ ЭНД АПДЖОН КОМПАНИ ЭлЭлСи | Оксиндол-оксазолидинон в качестве антибактериального агента |
| AU2006231919A1 (en) * | 2005-04-06 | 2006-10-12 | Pharmacia & Upjohn Company Llc | 7-fluoro-1,3-dihydro-indol-2-one oxazolidinones as antibacterial agents |
| AP2007004244A0 (en) | 2005-05-10 | 2007-12-31 | Intermune Inc | Method of modulating stress-activated protein kinase system |
| WO2007088478A1 (en) * | 2006-02-01 | 2007-08-09 | Pfizer Products Inc. | Indazole oxazolidinones as antibacterial agents |
| EP2004640A1 (en) * | 2006-02-08 | 2008-12-24 | Pfizer Products Inc. | Oxazolidinones containing oxindoles as antibacterial agents |
| EP2296653B1 (en) | 2008-06-03 | 2016-01-27 | Intermune, Inc. | Compounds and methods for treating inflammatory and fibrotic disorders |
| FR2948940B1 (fr) * | 2009-08-04 | 2011-07-22 | Servier Lab | Nouveaux derives dihydroindolones, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| JP5685384B2 (ja) * | 2010-03-29 | 2015-03-18 | 公益財団法人相模中央化学研究所 | ３，３−ジフルオロ−２，３−ジヒドロインドール−２−オン誘導体の製造方法 |
| AR092742A1 (es) | 2012-10-02 | 2015-04-29 | Intermune Inc | Piridinonas antifibroticas |
| HUE034106T2 (en) * | 2012-10-17 | 2018-01-29 | Univ Okayama | Compound, tautomer and geometric isomer thereof, compound, tautomer or salt of geometric isomer, process for preparing the compound, tautomer, isomer or salt, antimicrobial agent and anti-infectious drug |
| CN103193794B (zh) * | 2013-04-12 | 2016-04-06 | 中国药科大学 | 一种异吲哚酮并异噁唑类稠环化合物及其合成方法 |
| RU2692485C2 (ru) | 2014-04-02 | 2019-06-25 | Интермьюн, Инк. | Противофиброзные пиридиноны |
| CN107151225B (zh) * | 2017-06-30 | 2020-05-08 | 贵州大学 | 2-羟基吲哚类衍生物、其制备方法和用途 |
| CN113773306B (zh) * | 2021-10-29 | 2023-11-10 | 四川农业大学 | 3,3-二取代吲哚酮类化合物及其制备方法和应用 |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5225565A (en) * | 1988-09-15 | 1993-07-06 | The Upjohn Company | Antibacterial 3-(fused-ring substituted)phenyl-5β-amidomethyloxazolidin-2-ones |
| US5164510A (en) * | 1988-09-15 | 1992-11-17 | The Upjohn Company | 5'Indolinyl-5β-amidomethyloxazolidin-2-ones |
| ES2157934T3 (es) | 1988-09-15 | 2001-09-01 | Upjohn Co | Fenil-5-beta-amidometiloxazolidin-2-onas sustituidas con nitrogeno en la posicion 3. |
| MY115155A (en) | 1993-09-09 | 2003-04-30 | Upjohn Co | Substituted oxazine and thiazine oxazolidinone antimicrobials. |
| DE19514313A1 (de) * | 1994-08-03 | 1996-02-08 | Bayer Ag | Benzoxazolyl- und Benzothiazolyloxazolidinone |
| HRP960159A2 (en) | 1995-04-21 | 1997-08-31 | Bayer Ag | Benzocyclopentane oxazolidinones containing heteroatoms |
| DE19601627A1 (de) * | 1996-01-18 | 1997-07-24 | Bayer Ag | Heteroatomhaltige Cyclopentanopyridyl-Oxazolidinone |
| DE19604223A1 (de) * | 1996-02-06 | 1997-08-07 | Bayer Ag | Neue substituierte Oxazolidinone |
| DE19805117A1 (de) | 1998-02-09 | 1999-08-12 | Bayer Ag | Neue Oxazolidinone mit azolhaltigen Tricyclen |
| GB9812019D0 (en) * | 1998-06-05 | 1998-07-29 | Zeneca Ltd | Chemical compounds |
| EP1082323A2 (en) | 1998-06-05 | 2001-03-14 | AstraZeneca UK Limited | Oxazolidinone derivatives, process for their preparation and pharmaceutical compositions containing them |
| GB9821938D0 (en) | 1998-10-09 | 1998-12-02 | Zeneca Ltd | Chemical compounds |
| WO2000029409A1 (de) | 1998-11-17 | 2000-05-25 | Bayer Aktiengesellschaft | Neue heterocyclyl-substituierte oxazolidon-derivate |
| DE19962924A1 (de) | 1999-12-24 | 2001-07-05 | Bayer Ag | Substituierte Oxazolidinone und ihre Verwendung |
| PE20011124A1 (es) | 2000-03-31 | 2001-10-28 | Upjohn Co | Nuevos agentes antibacterianos de benzosultam oxazolidinona |
| GB0009803D0 (en) | 2000-04-25 | 2000-06-07 | Astrazeneca Ab | Chemical compounds |
| US8048386B2 (en) | 2002-02-25 | 2011-11-01 | Cepheid | Fluid processing and control |
| PE20030044A1 (es) | 2000-11-17 | 2003-02-09 | Upjohn Co | Isoxazolinonas biciclicas de formula i |
| JP2005512975A (ja) | 2001-10-25 | 2005-05-12 | アストラゼネカ アクチボラグ | 抗菌薬として有用なイソキサゾリン誘導体 |
-
2004
- 2004-01-22 US US10/762,838 patent/US7012088B2/en not_active Expired - Fee Related
- 2004-02-12 BR BR0406824-6A patent/BRPI0406824A/pt not_active IP Right Cessation
- 2004-02-12 AU AU2004213246A patent/AU2004213246A1/en not_active Abandoned
- 2004-02-12 WO PCT/IB2004/000466 patent/WO2004074282A1/en not_active Ceased
- 2004-02-12 MX MXPA05008960A patent/MXPA05008960A/es active IP Right Grant
- 2004-02-12 HR HR20050658A patent/HRP20050658A2/hr not_active Application Discontinuation
- 2004-02-12 GE GEAP20048948A patent/GEP20084306B/en unknown
- 2004-02-12 CN CNB2004800027371A patent/CN100349892C/zh not_active Expired - Fee Related
- 2004-02-12 EP EP04710451A patent/EP1599470A1/en not_active Withdrawn
- 2004-02-12 RS YUP-2005/0649A patent/RS20050649A/sr unknown
- 2004-02-12 JP JP2005518544A patent/JP3887396B2/ja not_active Expired - Fee Related
- 2004-02-12 AP AP2005003375A patent/AP2005003375A0/xx unknown
- 2004-02-12 EA EA200501341A patent/EA009725B1/ru not_active IP Right Cessation
- 2004-02-12 CA CA002515984A patent/CA2515984A1/en not_active Abandoned
- 2004-02-12 PL PL377428A patent/PL377428A1/pl not_active Application Discontinuation
- 2004-02-12 OA OA1200500233A patent/OA13032A/en unknown
- 2004-02-12 KR KR1020057015556A patent/KR100701226B1/ko not_active Expired - Fee Related
- 2004-12-02 UA UAA200509025A patent/UA80326C2/uk unknown
-
2005
- 2005-06-09 NO NO20052794A patent/NO20052794L/no not_active Application Discontinuation
- 2005-06-09 IS IS7883A patent/IS7883A/is unknown
- 2005-06-28 ZA ZA200505225A patent/ZA200505225B/en unknown
- 2005-08-19 CO CO05082195A patent/CO5601039A2/es not_active Application Discontinuation
- 2005-08-22 CR CR7956A patent/CR7956A/es unknown
- 2005-08-24 TN TNP2005000202A patent/TNSN05202A1/fr unknown
- 2005-08-24 EC EC2005005980A patent/ECSP055980A/es unknown
- 2005-08-24 MA MA28456A patent/MA27661A1/fr unknown
Also Published As
| Publication number | Publication date |
|---|---|
| PL377428A1 (pl) | 2006-02-06 |
| HRP20050658A2 (en) | 2005-12-31 |
| NO20052794L (no) | 2005-11-01 |
| CA2515984A1 (en) | 2004-09-02 |
| MA27661A1 (fr) | 2005-12-01 |
| ECSP055980A (es) | 2006-01-16 |
| KR20050102135A (ko) | 2005-10-25 |
| TNSN05202A1 (fr) | 2007-06-11 |
| BRPI0406824A (pt) | 2005-12-27 |
| CR7956A (es) | 2005-12-01 |
| JP2006515012A (ja) | 2006-05-18 |
| UA80326C2 (en) | 2007-09-10 |
| EA200501341A1 (ru) | 2006-02-24 |
| WO2004074282A1 (en) | 2004-09-02 |
| EA009725B1 (ru) | 2008-02-28 |
| CO5601039A2 (es) | 2006-01-31 |
| AP2005003375A0 (en) | 2005-09-30 |
| GEP20084306B (en) | 2008-02-11 |
| ZA200505225B (en) | 2006-11-29 |
| EP1599470A1 (en) | 2005-11-30 |
| JP3887396B2 (ja) | 2007-02-28 |
| HK1082253A1 (zh) | 2006-06-02 |
| IS7883A (is) | 2005-06-09 |
| US20040176610A1 (en) | 2004-09-09 |
| KR100701226B1 (ko) | 2007-03-29 |
| CN1742008A (zh) | 2006-03-01 |
| AU2004213246A1 (en) | 2004-09-02 |
| US7012088B2 (en) | 2006-03-14 |
| RS20050649A (sr) | 2007-11-15 |
| CN100349892C (zh) | 2007-11-21 |
| NO20052794D0 (no) | 2005-06-09 |
| MXPA05008960A (es) | 2005-11-04 |
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