BRPI0407844A - processo para preparação de formas enancioméricas de derivados de 1,3-ciclohexanodiol com configuração cis - Google Patents

processo para preparação de formas enancioméricas de derivados de 1,3-ciclohexanodiol com configuração cis

Info

Publication number
BRPI0407844A
BRPI0407844A BRPI0407844-6A BRPI0407844A BRPI0407844A BR PI0407844 A BRPI0407844 A BR PI0407844A BR PI0407844 A BRPI0407844 A BR PI0407844A BR PI0407844 A BRPI0407844 A BR PI0407844A
Authority
BR
Brazil
Prior art keywords
cis
preparing
forms
enanciomeric
configuration
Prior art date
Application number
BRPI0407844-6A
Other languages
English (en)
Inventor
Wolfgang Holla
Stefanie Keil
Original Assignee
Aventis Pharma Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Gmbh filed Critical Aventis Pharma Gmbh
Publication of BRPI0407844A publication Critical patent/BRPI0407844A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D263/32—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • C12P41/003—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions
    • C12P41/004—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions by esterification of alcohol- or thiol groups in the enantiomers or the inverse reaction
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Analytical Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

"PROCESSO PARA PREPARAçãO DE FORMAS ENANCIOMéRICAS DE DERIVADOS DE 1,3-CICLOHEXANODIOL COM CONFIGURAçãO CIS". Processo para preparação de formas enancioméricas de derivados de 1,3-ciclohexanodiol cis-configurados. é um processo para preparação de ciclohexanóis quirais, não-racêmicos, cis-configurados, 1,3-disubstituídos de fórmula (1), nos quais os radicais têm os significados indicados descritos, por meio de dissociação enzimática de racemato.
BRPI0407844-6A 2003-02-27 2004-02-19 processo para preparação de formas enancioméricas de derivados de 1,3-ciclohexanodiol com configuração cis BRPI0407844A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10308350A DE10308350B4 (de) 2003-02-27 2003-02-27 Verfahren zur Herstellung der enantiomeren Formen von cis-konfigurierten 1,3-Cyclohexandiol-Derivaten
PCT/EP2004/001580 WO2004076390A1 (de) 2003-02-27 2004-02-19 Verfahren zur herstellung der enantiomeren formen von cis-konfigurierten 1,3-cyclohexandiol-derivaten

Publications (1)

Publication Number Publication Date
BRPI0407844A true BRPI0407844A (pt) 2006-02-14

Family

ID=32863920

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0407844-6A BRPI0407844A (pt) 2003-02-27 2004-02-19 processo para preparação de formas enancioméricas de derivados de 1,3-ciclohexanodiol com configuração cis

Country Status (24)

Country Link
EP (1) EP1599433B1 (pt)
JP (1) JP2006519001A (pt)
KR (1) KR20050107469A (pt)
CN (1) CN100572348C (pt)
AR (1) AR044501A1 (pt)
AT (1) ATE347543T1 (pt)
AU (1) AU2004215674B2 (pt)
BR (1) BRPI0407844A (pt)
CA (1) CA2516623A1 (pt)
CO (1) CO5690547A2 (pt)
CY (1) CY1106454T1 (pt)
DE (2) DE10308350B4 (pt)
DK (1) DK1599433T3 (pt)
ES (1) ES2278305T3 (pt)
IL (1) IL170310A (pt)
MX (1) MXPA05009053A (pt)
NO (1) NO20054456L (pt)
NZ (1) NZ542025A (pt)
PL (1) PL377812A1 (pt)
PT (1) PT1599433E (pt)
RU (1) RU2372319C2 (pt)
TW (1) TWI331138B (pt)
WO (1) WO2004076390A1 (pt)
ZA (1) ZA200505760B (pt)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102004038403B4 (de) * 2004-08-07 2006-08-31 Sanofi-Aventis Deutschland Gmbh Verfahren zur Herstellung der enantiomeren Formen von cis-konfigurierten 3-Hydroxycyclohexancarbonsäure-Derivaten
DE102004040736B4 (de) * 2004-08-23 2007-01-11 Sanofi-Aventis Deutschland Gmbh Verfahren zur Herstellung von Diarylcycloalkylderivaten
CN101381302B (zh) * 2007-09-07 2013-04-03 上海睿智化学研究有限公司 2-溴甲基-6-甲基苯甲酰氯/溴的制备方法
EP2298755A4 (en) 2008-05-21 2012-12-05 Taisho Pharmaceutical Co Ltd PROCESS FOR PRODUCING BICYCLO [3.1.0] HEXANE DERIVATIVE WITH ENZYME
CN110446495B (zh) 2017-02-17 2023-09-05 特维娜有限公司 含有7元氮杂杂环的δ阿片受体调节化合物及其使用和制备方法
CN116406268A (zh) 2020-10-27 2023-07-07 特维娜有限公司 δ-阿片样物质调节剂的结晶和无定形形式
JP2024503380A (ja) * 2021-01-08 2024-01-25 サイブレクサ ２，インコーポレイテッド コンジュゲート連結部分を調製するための方法
WO2023070605A1 (en) * 2021-10-29 2023-05-04 Trevena, Inc. Methods of preparing 6-membered aza-heterocyclic containing delta-opioid receptor modulating compounds
CN114891838B (zh) * 2022-04-29 2023-09-08 株洲壹诺生物技术有限公司 盐酸多佐胺中间体(s)-3-(2-噻吩硫基)-丁酸的合成方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ515087A (en) * 1999-04-28 2003-11-28 Aventis Pharma Gmbh Tri-aryl acid derivatives as PPAR receptor ligands
DE10004926A1 (de) * 2000-02-04 2001-08-09 Gruenenthal Gmbh Verfahren zur enzymatischen Racematspaltung von Aminomethyl-Aryl-Cyclohexanol-Derivaten
BR0212158A (pt) * 2001-08-31 2004-07-13 Aventis Pharma Gmbh Derivados de diarilcicloalquila, processos para a sua preparação e sua aplicação como ativadores de ppar

Also Published As

Publication number Publication date
AU2004215674A1 (en) 2004-09-10
RU2005129993A (ru) 2006-01-27
PL377812A1 (pl) 2006-02-20
EP1599433B1 (de) 2006-12-06
TWI331138B (en) 2010-10-01
ATE347543T1 (de) 2006-12-15
CN1753855A (zh) 2006-03-29
DE10308350B4 (de) 2006-06-01
NZ542025A (en) 2009-03-31
ZA200505760B (en) 2006-05-31
TW200508392A (en) 2005-03-01
KR20050107469A (ko) 2005-11-11
CN100572348C (zh) 2009-12-23
RU2372319C2 (ru) 2009-11-10
DE10308350A1 (de) 2004-09-16
CO5690547A2 (es) 2006-10-31
PT1599433E (pt) 2007-02-28
CA2516623A1 (en) 2004-09-10
IL170310A (en) 2010-06-16
WO2004076390A1 (de) 2004-09-10
NO20054456L (no) 2005-09-26
CY1106454T1 (el) 2011-10-12
ES2278305T3 (es) 2007-08-01
DE502004002234D1 (de) 2007-01-18
AR044501A1 (es) 2005-09-14
EP1599433A1 (de) 2005-11-30
DK1599433T3 (da) 2007-04-16
HK1088889A1 (zh) 2006-11-17
AU2004215674B2 (en) 2010-02-04
JP2006519001A (ja) 2006-08-24
MXPA05009053A (es) 2005-10-19

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 8A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2159 DE 22/05/2012.