BRPI0408061A - tratamento médico utilizando um agonista de receptores seletivos de ep 2 - Google Patents

tratamento médico utilizando um agonista de receptores seletivos de ep 2

Info

Publication number: BRPI0408061A
Authority: BR; Brazil
Prior art keywords: facilitating; receptor agonist; treating; repair; medical treatment
Prior art date: 2003-03-04

Application number

BRPI0408061-0A

Other languages

English (en)

Portuguese (pt)

Inventor

Alexander Angelo Constan

Prakash Raj Keshary

David Burton Maclean

Vishwas Madhav Paralkar

Doina Cosma Roman

David Duane Thompson

Timothy Michael Wright

Original Assignee

Pfizer Prod Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2003-03-04

Filing date

2004-02-23

Publication date

2006-02-14

2004-02-23 Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc

2006-02-14 Publication of BRPI0408061A publication Critical patent/BRPI0408061A/pt

Links

239000000018 receptor agonist Substances 0.000 title abstract 3
229940044601 receptor agonist Drugs 0.000 title abstract 3
208000030016 Avascular necrosis Diseases 0.000 abstract 1
208000010392 Bone Fractures Diseases 0.000 abstract 1
206010017076 Fracture Diseases 0.000 abstract 1
208000010412 Glaucoma Diseases 0.000 abstract 1
206010020772 Hypertension Diseases 0.000 abstract 1
208000037848 Metastatic bone disease Diseases 0.000 abstract 1
206010030043 Ocular hypertension Diseases 0.000 abstract 1
206010031264 Osteonecrosis Diseases 0.000 abstract 1
208000025865 Ulcer Diseases 0.000 abstract 1
210000000988 bone and bone Anatomy 0.000 abstract 1
210000000845 cartilage Anatomy 0.000 abstract 1
210000003298 dental enamel Anatomy 0.000 abstract 1
230000004927 fusion Effects 0.000 abstract 1
230000002496 gastric effect Effects 0.000 abstract 1
230000035876 healing Effects 0.000 abstract 1
230000003902 lesion Effects 0.000 abstract 1
210000003041 ligament Anatomy 0.000 abstract 1
210000004185 liver Anatomy 0.000 abstract 1
238000000034 method Methods 0.000 abstract 1
208000002815 pulmonary hypertension Diseases 0.000 abstract 1
230000008929 regeneration Effects 0.000 abstract 1
238000011069 regeneration method Methods 0.000 abstract 1
210000002435 tendon Anatomy 0.000 abstract 1
210000004906 toe nail Anatomy 0.000 abstract 1
238000002054 transplantation Methods 0.000 abstract 1
230000036269 ulceration Effects 0.000 abstract 1
230000029663 wound healing Effects 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/433—Thidiazoles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives

Landscapes

Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical Kinetics & Catalysis (AREA)
Organic Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Epidemiology (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Ophthalmology & Optometry (AREA)
Physical Education & Sports Medicine (AREA)
Pulmonology (AREA)
Dermatology (AREA)
Gastroenterology & Hepatology (AREA)
Immunology (AREA)
Orthopedic Medicine & Surgery (AREA)
Rheumatology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Heterocyclic Compounds Containing Sulfur Atoms (AREA)
Pyridine Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

BRPI0408061-0A 2003-03-04 2004-02-23 tratamento médico utilizando um agonista de receptores seletivos de ep 2 BRPI0408061A (pt)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US45188903P	2003-03-04	2003-03-04
PCT/IB2004/000553 WO2004078169A1 (en)	2003-03-04	2004-02-23	Use of ep2 selective receptor agonists in medical treatment

Publications (1)

Publication Number	Publication Date
BRPI0408061A true BRPI0408061A (pt)	2006-02-14

Family

ID=32962656

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BRPI0408061-0A BRPI0408061A (pt)	2003-03-04	2004-02-23	tratamento médico utilizando um agonista de receptores seletivos de ep 2

Country Status (14)

Country	Link
EP (1)	EP1601351A1 (pl)
JP (1)	JP2006519250A (pl)
KR (1)	KR20050105511A (pl)
CN (1)	CN1859903A (pl)
AU (1)	AU2004216898A1 (pl)
BR (1)	BRPI0408061A (pl)
CA (1)	CA2518193A1 (pl)
CL (1)	CL2004000412A1 (pl)
MX (1)	MXPA05009398A (pl)
NZ (1)	NZ541828A (pl)
PL (1)	PL378748A1 (pl)
TW (1)	TW200424176A (pl)
WO (1)	WO2004078169A1 (pl)
ZA (1)	ZA200506532B (pl)

Families Citing this family (35)

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GB0302094D0 (en)	2003-01-29	2003-02-26	Pharmagene Lab Ltd	EP4 receptor antagonists
US20070270489A1 (en) *	2003-07-25	2007-11-22	Ono Pharmaceutical Co., Ltd.	Remedy for Cartilage-Related Diseases
GB0324269D0 (en)	2003-10-16	2003-11-19	Pharmagene Lab Ltd	EP4 receptor antagonists
DK1848430T3 (da)	2004-12-31	2017-11-06	Dr Reddys Laboratories Ltd	Nye benzylamin-derivativer som cetp-inhibitors
US8604055B2 (en)	2004-12-31	2013-12-10	Dr. Reddy's Laboratories Ltd.	Substituted benzylamino quinolines as cholesterol ester-transfer protein inhibitors
US7915316B2 (en) *	2005-08-22	2011-03-29	Allergan, Inc	Sulfonamides
US7696235B2 (en)	2005-08-29	2010-04-13	Allergan, Inc.	EP2 receptor agonists for treating glaucoma
JP5247675B2 (ja)	2006-03-24	2013-07-24	チルドレンズメディカルセンターコーポレーション	造血性幹細胞の増殖を調節する方法
NZ573964A (en)	2006-07-28	2010-11-26	Pfizer Prod Inc	isopropyl [3-({[4-(1H-pyrazol-1-yl)benzyl](pyridin-3-ylsulfonyl)-amino}methyl)phenoxy]acetate, a prostaglandin E2 receptor agonist (EP2), useful in lower intraocular pressure thereby treating glaucoma
JP5426389B2 (ja) *	2006-10-20	2014-02-26	チルドレンズメディカルセンターコーポレーション	組織の再生を亢進するための方法
CN101828111B (zh) *	2007-08-21	2014-07-23	塞诺米克斯公司	人t2r苦味受体及其用途
CN103965099A (zh) *	2008-03-12	2014-08-06	宇部兴产株式会社	吡啶基氨基乙酸化合物
WO2010096264A2 (en)	2009-02-03	2010-08-26	Children's Medical Center Corporation	Methods for enhancing hematopoietic stem/progenitor cell engraftment
US9051548B2 (en)	2009-02-03	2015-06-09	Children's Medical Center Corporation	Methods for enhancing hematopoietic stem/progenitor cell engraftment
PL2415763T3 (pl)	2009-03-30	2016-05-31	Ube Industries	Kompozycja farmaceutyczna do leczenia lub profilaktyki jaskry
WO2010116270A1 (en)	2009-04-10	2010-10-14	Pfizer Inc.	Ep2/4 agonists
WO2011030873A1 (ja) *	2009-09-11	2011-03-17	宇部興産株式会社	ベンジル化合物
CN102548985A (zh) *	2009-09-11	2012-07-04	宇部兴产株式会社	取代羰基化合物
WO2011030872A1 (ja) *	2009-09-11	2011-03-17	宇部興産株式会社	スルホンアミド化合物
WO2011030865A1 (ja) *	2009-09-11	2011-03-17	宇部興産株式会社	置換ベンジル化合物
JP2011057633A (ja) *	2009-09-11	2011-03-24	Ube Industries Ltd	ピリジルアミノ酢酸化合物を含有する医薬
CN102498101A (zh) *	2009-09-11	2012-06-13	宇部兴产株式会社	苯胺化合物
WO2011030871A1 (ja) *	2009-09-11	2011-03-17	宇部興産株式会社	Ｎ－置換ヘテロアリール化合物
WO2011078303A1 (ja)	2009-12-25	2011-06-30	宇部興産株式会社	アミノピリジン化合物
KR101774223B1 (ko)	2011-08-18	2017-09-12	닥터 레디스 레보러터리즈 리미티드	콜레스테릴 에스테르-전달 단백질(cetp) 억제제인 치환된 헤테로시클릭 아민 화합물
HK1197238A1 (en)	2011-09-27	2015-01-09	雷迪博士实验室有限公司	5 - benzylaminomethyl - 6 - aminopyrazolo [3, 4 -b] pyridine derivatives as cholesteryl ester -transfer protein (cetp) inhibitors useful for the treatment of atherosclerosis
CA2857640C (en)	2011-12-02	2021-11-16	Fate Therapeutics, Inc.	Enhanced stem cell composition
ES2682255T3 (es)	2011-12-02	2018-09-19	Fate Therapeutics, Inc.	Métodos mejorados de tratamiento de isquemia
EP2804605A4 (en) *	2012-01-20	2015-07-08	Acucela Inc	SUBSTITUTED HETEROCYCLIC COMPOUNDS FOR THE TREATMENT OF DISEASES
US20140142092A1 (en) *	2012-11-16	2014-05-22	Allergan, Inc.	Compounds and methods for skin repair
US10851412B2 (en)	2013-03-15	2020-12-01	Fate Therapeutics, Inc.	Cell potency assay for therapeutic potential
JPWO2014157672A1 (ja)	2013-03-28	2017-02-16	宇部興産株式会社	置換ビアリール化合物
EP4474384A1 (en)	2014-05-13	2024-12-11	Novartis AG	Compounds and compositions for inducing chondrogenesis
CN106397149B (zh) *	2016-08-26	2019-05-21	大连奇凯医药科技有限公司	五氟苯甲醛的制备方法
CN115636761B (zh) *	2021-07-20	2024-07-05	中国石油天然气股份有限公司	一种油溶性表面活性剂、驱油剂及其应用

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CA2113787A1 (en) *	1993-01-29	1994-07-30	Nobuyuki Hamanaka	Carbocyclic sulfonamides
DK0951282T3 (da) *	1996-12-20	2008-07-14	Pfizer	Forebyggelse og behandling af skeletlidelse med EP2-receptorsubtype-selektive prostaglandin E2-agonister
UA67754C2 (uk) *	1997-10-10	2004-07-15	Пфайзер, Інк.	Агоністи простагландину, фармацевтична композиція на їх основі (варіанти), спосіб нарощення та збереження кісткової маси у хребетних та спосіб лікування (варіанти)
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2004
- 2004-02-23 AU AU2004216898A patent/AU2004216898A1/en not_active Abandoned
- 2004-02-23 JP JP2006506276A patent/JP2006519250A/ja not_active Withdrawn
- 2004-02-23 MX MXPA05009398A patent/MXPA05009398A/es unknown
- 2004-02-23 WO PCT/IB2004/000553 patent/WO2004078169A1/en not_active Ceased
- 2004-02-23 EP EP04713611A patent/EP1601351A1/en not_active Withdrawn
- 2004-02-23 CN CNA2004800085767A patent/CN1859903A/zh active Pending
- 2004-02-23 KR KR1020057016414A patent/KR20050105511A/ko not_active Ceased
- 2004-02-23 BR BRPI0408061-0A patent/BRPI0408061A/pt not_active IP Right Cessation
- 2004-02-23 PL PL378748A patent/PL378748A1/pl not_active Application Discontinuation
- 2004-02-23 CA CA002518193A patent/CA2518193A1/en not_active Abandoned
- 2004-02-23 NZ NZ541828A patent/NZ541828A/en unknown
- 2004-03-01 TW TW093105312A patent/TW200424176A/zh unknown
- 2004-03-02 CL CL200400412A patent/CL2004000412A1/es unknown
2005
- 2005-08-16 ZA ZA200506532A patent/ZA200506532B/en unknown

Also Published As

Publication number	Publication date
JP2006519250A (ja)	2006-08-24
CN1859903A (zh)	2006-11-08
TW200424176A (en)	2004-11-16
AU2004216898A1 (en)	2004-09-16
KR20050105511A (ko)	2005-11-04
WO2004078169A8 (en)	2005-04-21
ZA200506532B (en)	2007-03-28
NZ541828A (en)	2008-06-30
MXPA05009398A (es)	2005-12-05
CA2518193A1 (en)	2004-09-16
EP1601351A1 (en)	2005-12-07
CL2004000412A1 (es)	2005-02-04
WO2004078169A1 (en)	2004-09-16
PL378748A1 (pl)	2006-05-15

Legal Events

Date	Code	Title	Description
2011-10-25	B08F	Application fees: application dismissed [chapter 8.6 patent gazette]	Free format text: REFERENTE A 6A E 7A ANUIDADES.
2012-05-15	B08K	Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]	Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2129 DE 25/10/2011.

Publication	Publication Date	Title
BRPI0408061A (pt)	2006-02-14	tratamento médico utilizando um agonista de receptores seletivos de ep 2
Schön et al.	2003	Follow-up of condylar fractures of the mandible in 8 patients at 18 months after transoral endoscopic-assisted open treatment
PT881908E (pt)	2004-11-30	Utilizacao dos factores de crescimento de fibroblasto para estimular o crescimento osseo
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Walker	1988	Discussion: Open reduction of condylar fractures of the mandible in conjunction with repair of discal injury: A preliminary report
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