BRPI0408506A - processos para isolamento de forma i cristalina de 5-azacitidina - Google Patents

processos para isolamento de forma i cristalina de 5-azacitidina

Info

Publication number
BRPI0408506A
BRPI0408506A BRPI0408506-0A BRPI0408506A BRPI0408506A BR PI0408506 A BRPI0408506 A BR PI0408506A BR PI0408506 A BRPI0408506 A BR PI0408506A BR PI0408506 A BRPI0408506 A BR PI0408506A
Authority
BR
Brazil
Prior art keywords
azacytidine
processes
isolation
crystalline form
crystaline
Prior art date
Application number
BRPI0408506-0A
Other languages
English (en)
Inventor
Dumitru Ionescu
Peter Blumbergs
Gary L Silvey
Original Assignee
Pharmion Corp
Ash Stevens Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=32987551&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BRPI0408506(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Pharmion Corp, Ash Stevens Inc filed Critical Pharmion Corp
Publication of BRPI0408506A publication Critical patent/BRPI0408506A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives
    • C07H1/06—Separation; Purification
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/12—Triazine radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Hematology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

"PROCESSOS PARA ISOLAMENTO DE FORMA I CRISTALINA DE 5-AZACITIDINA". A invenção inclui processos para isolamento de Forma I cristlaina de 5-azacitidina substancialmente livre de outras formas, onde 5-azacitidina é representada pela fórmula: A Invenção também inclui composições farmacêuticas compreendendo Forma I de 5-azacitidina.
BRPI0408506-0A 2003-03-17 2004-03-16 processos para isolamento de forma i cristalina de 5-azacitidina BRPI0408506A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10/390,530 US6943249B2 (en) 2003-03-17 2003-03-17 Methods for isolating crystalline Form I of 5-azacytidine
PCT/US2004/007896 WO2004082822A2 (en) 2003-03-17 2004-03-16 Methods for isolating crystalline form i of 5-azacytidine

Publications (1)

Publication Number Publication Date
BRPI0408506A true BRPI0408506A (pt) 2006-03-14

Family

ID=32987551

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0408506-0A BRPI0408506A (pt) 2003-03-17 2004-03-16 processos para isolamento de forma i cristalina de 5-azacitidina

Country Status (16)

Country Link
US (5) US6943249B2 (pt)
EP (3) EP2266965A1 (pt)
JP (1) JP4792550B2 (pt)
AU (2) AU2004222274B2 (pt)
BR (1) BRPI0408506A (pt)
CA (1) CA2518973A1 (pt)
CY (2) CY1114213T1 (pt)
DK (2) DK2181988T3 (pt)
EC (1) ECSP056023A (pt)
ES (2) ES2575535T3 (pt)
HU (1) HUE028268T2 (pt)
MX (1) MXPA05009969A (pt)
PL (2) PL1608634T3 (pt)
PT (2) PT1608634E (pt)
SI (2) SI1608634T1 (pt)
WO (1) WO2004082822A2 (pt)

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CN103450303A (zh) * 2013-09-04 2013-12-18 重庆泰濠制药有限公司 阿扎胞苷晶型a、阿扎胞苷晶型b及其制备方法
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Also Published As

Publication number Publication date
ECSP056023A (es) 2006-01-27
ES2425474T3 (es) 2013-10-15
PL2181988T3 (pl) 2016-11-30
US6943249B2 (en) 2005-09-13
US8975392B2 (en) 2015-03-10
US8481715B2 (en) 2013-07-09
JP2006523210A (ja) 2006-10-12
SI1608634T1 (sl) 2013-09-30
PL1608634T3 (pl) 2013-10-31
CA2518973A1 (en) 2004-09-30
EP1608634B1 (en) 2013-05-22
US20130274459A1 (en) 2013-10-17
US20120245342A1 (en) 2012-09-27
AU2004222274A1 (en) 2004-09-30
EP1608634A2 (en) 2005-12-28
AU2004222274B2 (en) 2010-11-04
AU2010241198A1 (en) 2010-11-25
DK2181988T3 (en) 2016-06-06
MXPA05009969A (es) 2006-02-17
ES2575535T3 (es) 2016-06-29
US20040186284A1 (en) 2004-09-23
DK1608634T3 (da) 2013-08-12
US7700770B2 (en) 2010-04-20
JP4792550B2 (ja) 2011-10-12
WO2004082822A2 (en) 2004-09-30
EP2181988A1 (en) 2010-05-05
US20100292180A1 (en) 2010-11-18
SI2181988T1 (sl) 2016-09-30
PT2181988E (pt) 2016-06-15
US20050272675A1 (en) 2005-12-08
US8211862B2 (en) 2012-07-03
EP1608634A4 (en) 2006-03-15
WO2004082822A3 (en) 2005-07-07
EP2266965A1 (en) 2010-12-29
CY1117639T1 (el) 2017-04-26
HUE028268T2 (en) 2016-12-28
PT1608634E (pt) 2013-08-27
CY1114213T1 (el) 2016-08-31
AU2010241198B2 (en) 2012-05-10
EP2181988B1 (en) 2016-05-11

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Legal Events

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B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B25A Requested transfer of rights approved

Owner name: ASH STEVENS INC. (US) , COBALT ACQUISITION LLC (CH

Free format text: TRANSFERIDO POR FUSAO DE: PHARMION CORPORATION

B25D Requested change of name of applicant approved

Owner name: ASH STEVENS INC. (US) , PHARMION LLC (CH)

Free format text: NOME ALTERADO DE: COBALT ACQUISITION LLC

B25A Requested transfer of rights approved

Owner name: ASH STEVENS INC. (US) , CELGENE INTERNATIONAL SARL

Free format text: TRANSFERIDO DE: PHARMION LLC

B25A Requested transfer of rights approved

Owner name: CELGENE INTERNATIONAL SARL (CH)

Free format text: TRANSFERIDO DE: ASH STEVENS INC.

B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]
B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]