PL1608634T3 - Sposób wyodrębniania krystalicznej formy i 5-azacytydyny - Google Patents

Sposób wyodrębniania krystalicznej formy i 5-azacytydyny

Info

Publication number
PL1608634T3
PL1608634T3 PL04721078T PL04721078T PL1608634T3 PL 1608634 T3 PL1608634 T3 PL 1608634T3 PL 04721078 T PL04721078 T PL 04721078T PL 04721078 T PL04721078 T PL 04721078T PL 1608634 T3 PL1608634 T3 PL 1608634T3
Authority
PL
Poland
Prior art keywords
azacytidine
methods
crystalline form
isolating crystalline
isolating
Prior art date
Application number
PL04721078T
Other languages
English (en)
Inventor
Dumitru Ionescu
Peter Blumbergs
Lee Alani Selvey
Original Assignee
Celgene Int Sarl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=32987551&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PL1608634(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Celgene Int Sarl filed Critical Celgene Int Sarl
Publication of PL1608634T3 publication Critical patent/PL1608634T3/pl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives
    • C07H1/06—Separation; Purification
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/12—Triazine radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Hematology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicinal Preparation (AREA)
PL04721078T 2003-03-17 2004-03-16 Sposób wyodrębniania krystalicznej formy i 5-azacytydyny PL1608634T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US10/390,530 US6943249B2 (en) 2003-03-17 2003-03-17 Methods for isolating crystalline Form I of 5-azacytidine
PCT/US2004/007896 WO2004082822A2 (en) 2003-03-17 2004-03-16 Methods for isolating crystalline form i of 5-azacytidine
EP04721078.6A EP1608634B1 (en) 2003-03-17 2004-03-16 Methods for isolating crystalline form i of 5-azacytidine

Publications (1)

Publication Number Publication Date
PL1608634T3 true PL1608634T3 (pl) 2013-10-31

Family

ID=32987551

Family Applications (2)

Application Number Title Priority Date Filing Date
PL04721078T PL1608634T3 (pl) 2003-03-17 2004-03-16 Sposób wyodrębniania krystalicznej formy i 5-azacytydyny
PL10151392.7T PL2181988T3 (pl) 2003-03-17 2004-03-16 Kompozycje farmaceutyczne oparte na Krystalicznej Postaci I 5-azacytydyny

Family Applications After (1)

Application Number Title Priority Date Filing Date
PL10151392.7T PL2181988T3 (pl) 2003-03-17 2004-03-16 Kompozycje farmaceutyczne oparte na Krystalicznej Postaci I 5-azacytydyny

Country Status (16)

Country Link
US (5) US6943249B2 (pl)
EP (3) EP1608634B1 (pl)
JP (1) JP4792550B2 (pl)
AU (2) AU2004222274B2 (pl)
BR (1) BRPI0408506A (pl)
CA (1) CA2518973A1 (pl)
CY (2) CY1114213T1 (pl)
DK (2) DK2181988T3 (pl)
EC (1) ECSP056023A (pl)
ES (2) ES2575535T3 (pl)
HU (1) HUE028268T2 (pl)
MX (1) MXPA05009969A (pl)
PL (2) PL1608634T3 (pl)
PT (2) PT1608634E (pl)
SI (2) SI1608634T1 (pl)
WO (1) WO2004082822A2 (pl)

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EP2211870A1 (en) * 2007-11-01 2010-08-04 Celgene Corporation Cytidine analogs for treatment of myelodysplastic syndromes
PL3692983T3 (pl) * 2008-05-15 2021-12-27 Celgene Corporation Doustne formulacje analogów cytydyny i sposoby ich zastosowania
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CA2849708A1 (en) 2011-09-23 2013-03-28 Celgene Corporation Romidepsin and 5 - azacitidine for use in treating lymphoma
CA2849903A1 (en) 2011-09-26 2013-04-04 Celgene Corporation Combination therapy for chemoresistant cancers
KR101987861B1 (ko) 2011-11-03 2019-06-11 밀레니엄 파머슈티컬스 인코퍼레이티드 Nedd-8 활성화 효소 억제제 및 저메틸화제의 투여
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US9669048B2 (en) * 2012-10-25 2017-06-06 Fresenius Kabi Oncology Limited Stable pharmaceutical composition of 5-aza-2′-deoxycitidine
WO2014076616A2 (en) * 2012-11-19 2014-05-22 Shilpa Medicare Limited Formulations of 5-azacytidine
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WO2014160698A1 (en) 2013-03-26 2014-10-02 Celgene Corporation SOLID FORMS COMPRISING 4-AMINO-I-β-D-RIBOFURANOSYL-1,3,5-TRIAZIN-2(1H)-ONE AND A COFORMER, COMPOSITIONS AND METHODS OF USE THEREOF
CN103450303A (zh) * 2013-09-04 2013-12-18 重庆泰濠制药有限公司 阿扎胞苷晶型a、阿扎胞苷晶型b及其制备方法
AU2015305449B2 (en) 2014-08-22 2021-05-06 Celgene Corporation Methods of treating multiple myeloma with immunomodulatory compounds in combination with antibodies
US20160095925A1 (en) * 2014-10-01 2016-04-07 Cadila Healthcare Limited Stable formulation of azacitidine or salts thereof and their process for preparation
US10695352B2 (en) 2015-10-15 2020-06-30 Celgene Corporation Combination therapy for treating malignancies
KR102699521B1 (ko) 2015-10-15 2024-08-26 르 라보레또레 쎄르비에르 악성 종양의 치료를 위한 조합물 요법
EP3527226A4 (en) * 2016-10-17 2020-06-17 Daiichi Sankyo Company, Limited COMBINATION THERAPY PROCEDURE WITH MDM2 INHIBITOR AND DNA METHYL TRANSFERASE INHIBITOR
CN109988207B (zh) * 2017-12-29 2022-01-04 江苏豪森药业集团有限公司 阿扎胞苷晶型的制备方法
US10632211B2 (en) 2018-06-11 2020-04-28 The Regents Of The University Of California Demethylation to treat eye disease
CN110642901A (zh) * 2019-11-11 2020-01-03 扬子江药业集团有限公司 阿扎胞苷甲醇化物及其制备方法和药物组合物、用途
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Also Published As

Publication number Publication date
WO2004082822A2 (en) 2004-09-30
MXPA05009969A (es) 2006-02-17
EP1608634A2 (en) 2005-12-28
DK2181988T3 (en) 2016-06-06
EP2181988A1 (en) 2010-05-05
HUE028268T2 (en) 2016-12-28
US20130274459A1 (en) 2013-10-17
DK1608634T3 (da) 2013-08-12
JP2006523210A (ja) 2006-10-12
US20120245342A1 (en) 2012-09-27
AU2010241198B2 (en) 2012-05-10
SI1608634T1 (sl) 2013-09-30
AU2004222274B2 (en) 2010-11-04
US7700770B2 (en) 2010-04-20
US8975392B2 (en) 2015-03-10
US8211862B2 (en) 2012-07-03
EP2181988B1 (en) 2016-05-11
CY1114213T1 (el) 2016-08-31
CY1117639T1 (el) 2017-04-26
EP1608634B1 (en) 2013-05-22
PT1608634E (pt) 2013-08-27
US20100292180A1 (en) 2010-11-18
US20040186284A1 (en) 2004-09-23
AU2010241198A1 (en) 2010-11-25
US6943249B2 (en) 2005-09-13
BRPI0408506A (pt) 2006-03-14
ECSP056023A (es) 2006-01-27
AU2004222274A1 (en) 2004-09-30
WO2004082822A3 (en) 2005-07-07
EP1608634A4 (en) 2006-03-15
PT2181988E (pt) 2016-06-15
ES2425474T3 (es) 2013-10-15
CA2518973A1 (en) 2004-09-30
EP2266965A1 (en) 2010-12-29
ES2575535T3 (es) 2016-06-29
PL2181988T3 (pl) 2016-11-30
US8481715B2 (en) 2013-07-09
US20050272675A1 (en) 2005-12-08
SI2181988T1 (sl) 2016-09-30
JP4792550B2 (ja) 2011-10-12

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