BRPI0408707A - métodos e aparelhos para a comunicação e estabilização de partìculas pequenas - Google Patents
métodos e aparelhos para a comunicação e estabilização de partìculas pequenasInfo
- Publication number
- BRPI0408707A BRPI0408707A BRPI0408707-0A BRPI0408707A BRPI0408707A BR PI0408707 A BRPI0408707 A BR PI0408707A BR PI0408707 A BRPI0408707 A BR PI0408707A BR PI0408707 A BRPI0408707 A BR PI0408707A
- Authority
- BR
- Brazil
- Prior art keywords
- methods
- stabilization
- communication
- small particles
- fluid stream
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S516/00—Colloid systems and wetting agents; subcombinations thereof; processes of
- Y10S516/924—Significant dispersive or manipulative operation or step in making or stabilizing colloid system
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S516/00—Colloid systems and wetting agents; subcombinations thereof; processes of
- Y10S516/924—Significant dispersive or manipulative operation or step in making or stabilizing colloid system
- Y10S516/925—Phase inversion
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S977/00—Nanotechnology
- Y10S977/84—Manufacture, treatment, or detection of nanostructure
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Dispersion Chemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Physical Or Chemical Processes And Apparatus (AREA)
- Colloid Chemistry (AREA)
Abstract
"MéTODOS E APARELHOS PARA A COMUNICAçãO E ESTABILIZAçãO DE PARTìCULAS PEQUENAS". A presente invenção refere-se a métodos e aparelhos para triturar e estabilizar partículas pequenas. Em uma concretização, um aparelho se move em um composto orgânico dissolvido em um solvente para formar uma suspensão de partículas em uma primeira corrente de fluido e se move a suspensão em uma segunda corrente de fluido, em que a segunda corrente de fluido é orientada e é posicionada com relação à primeira corrente para causar cisalhamente entre as correntes e misturação de pelo menos algumas das partículas na primeira e segunda correntes.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US45742403P | 2003-03-24 | 2003-03-24 | |
| US10/806,050 US7511079B2 (en) | 2003-03-24 | 2004-03-22 | Methods and apparatuses for the comminution and stabilization of small particles |
| PCT/US2004/009242 WO2004084860A2 (en) | 2003-03-24 | 2004-03-24 | Methods for the comminution and stabilization of small particles in suspension |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0408707A true BRPI0408707A (pt) | 2006-03-07 |
Family
ID=33101285
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0408707-0A BRPI0408707A (pt) | 2003-03-24 | 2004-03-24 | métodos e aparelhos para a comunicação e estabilização de partìculas pequenas |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US7511079B2 (pt) |
| EP (1) | EP1605915A2 (pt) |
| JP (1) | JP2006521396A (pt) |
| KR (1) | KR20050115298A (pt) |
| AU (1) | AU2004224307A1 (pt) |
| BR (1) | BRPI0408707A (pt) |
| CA (1) | CA2519536A1 (pt) |
| MX (1) | MXPA05010045A (pt) |
| NO (1) | NO20054908L (pt) |
| WO (1) | WO2004084860A2 (pt) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2004030659A1 (en) * | 2002-09-30 | 2004-04-15 | Acusphere, Inc. | Sustained release porous microparticles for inhalation |
| US20040121003A1 (en) * | 2002-12-19 | 2004-06-24 | Acusphere, Inc. | Methods for making pharmaceutical formulations comprising deagglomerated microparticles |
| US6962006B2 (en) * | 2002-12-19 | 2005-11-08 | Acusphere, Inc. | Methods and apparatus for making particles using spray dryer and in-line jet mill |
| US7511079B2 (en) | 2003-03-24 | 2009-03-31 | Baxter International Inc. | Methods and apparatuses for the comminution and stabilization of small particles |
| BRPI0414907A (pt) * | 2003-09-30 | 2006-11-07 | Acusphere Inc | formulações farmacêuticas com liberação sustentada injetáveis, orais ou tópicas |
| DE502006005846D1 (de) * | 2005-04-13 | 2010-02-25 | Abbott Gmbh & Co Kg | Verfahren zur schonenden herstellung hochfeiner partikelsuspensionen und hochfeiner partikel sowie deren verwendung |
| DE102005053862A1 (de) * | 2005-11-04 | 2007-05-10 | Pharmasol Gmbh | Verfahren und Vorrichtung zur Herstellung hochfeiner Partikel sowie zur Beschichtung solcher Partikel |
| US7913223B2 (en) * | 2005-12-16 | 2011-03-22 | Dialogic Corporation | Method and system for development and use of a user-interface for operations, administration, maintenance and provisioning of a telecommunications system |
| US8946200B2 (en) * | 2006-11-02 | 2015-02-03 | Southwest Research Institute | Pharmaceutically active nanosuspensions |
| US8282266B2 (en) | 2007-06-27 | 2012-10-09 | H R D Corporation | System and process for inhibitor injection |
| US20090187135A1 (en) * | 2008-01-18 | 2009-07-23 | Eilaz Babaev | Ultrasonic syringe |
| US8404850B2 (en) * | 2008-03-13 | 2013-03-26 | Southwest Research Institute | Bis-quaternary pyridinium-aldoxime salts and treatment of exposure to cholinesterase inhibitors |
| US8187554B2 (en) | 2008-04-23 | 2012-05-29 | Microfluidics International Corporation | Apparatus and methods for nanoparticle generation and process intensification of transport and reaction systems |
| US8722706B2 (en) * | 2008-08-15 | 2014-05-13 | Southwest Research Institute | Two phase bioactive formulations of bis-quaternary pyridinium oxime sulfonate salts |
| US8309134B2 (en) * | 2008-10-03 | 2012-11-13 | Southwest Research Institute | Modified calcium phosphate nanoparticle formation |
| US9028873B2 (en) * | 2010-02-08 | 2015-05-12 | Southwest Research Institute | Nanoparticles for drug delivery to the central nervous system |
| US10350556B2 (en) | 2011-01-07 | 2019-07-16 | Microfluidics International Corporation | Low holdup volume mixing chamber |
| US9079140B2 (en) | 2011-04-13 | 2015-07-14 | Microfluidics International Corporation | Compact interaction chamber with multiple cross micro impinging jets |
| US9199209B2 (en) | 2011-04-13 | 2015-12-01 | Microfluidics International Corporation | Interaction chamber with flow inlet optimization |
| BR112015014523A2 (pt) * | 2012-12-19 | 2017-07-11 | Kashiv Pharma Llc | nanossuspensão estabilizada, composição farmacêutica, e, método de tratamento de um paciente |
| JP6462403B2 (ja) * | 2015-02-23 | 2019-01-30 | 大川原化工機株式会社 | 湿式分散器 |
| WO2019246615A1 (en) | 2018-06-22 | 2019-12-26 | Delphi Scientific, Llc | Apparatus, systems, and methods for continuous manufacturing of nanomaterials and high purity chemicals |
| MX2021001814A (es) * | 2018-08-22 | 2021-07-02 | Avalyn Pharma Inc | Composiciones formuladas especialmente de nintedanib inhalado y sales de nintedanib. |
Family Cites Families (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3685261A (en) * | 1971-02-16 | 1972-08-22 | Environeering | Wet scrubber for contaminated gas |
| US4908154A (en) * | 1981-04-17 | 1990-03-13 | Biotechnology Development Corporation | Method of forming a microemulsion |
| CA1282405C (en) | 1984-05-21 | 1991-04-02 | Michael R. Violante | Method for making uniformly sized particles from water-insoluble organic compounds |
| DE69112917T2 (de) * | 1990-06-15 | 1996-05-15 | Merck & Co Inc | Kristallisationsverfahren zur Verbesserung der Kristallstruktur und -grösse. |
| DE4241549A1 (de) * | 1992-12-10 | 1994-06-16 | Nied Roland | Verfahren und Vorrichtung für die Prallzerkleinerung von Feststoffpartikeln |
| JPH07328471A (ja) * | 1994-06-06 | 1995-12-19 | Furukawa Co Ltd | 粉砕装置 |
| US5720551A (en) * | 1994-10-28 | 1998-02-24 | Shechter; Tal | Forming emulsions |
| SE9403846D0 (sv) * | 1994-11-09 | 1994-11-09 | Univ Ohio State Res Found | Small particle formation |
| DE4440337A1 (de) * | 1994-11-11 | 1996-05-15 | Dds Drug Delivery Services Ges | Pharmazeutische Nanosuspensionen zur Arzneistoffapplikation als Systeme mit erhöhter Sättigungslöslichkeit und Lösungsgeschwindigkeit |
| SE9501384D0 (sv) * | 1995-04-13 | 1995-04-13 | Astra Ab | Process for the preparation of respirable particles |
| US5833891A (en) * | 1996-10-09 | 1998-11-10 | The University Of Kansas | Methods for a particle precipitation and coating using near-critical and supercritical antisolvents |
| JPH10137618A (ja) * | 1996-11-14 | 1998-05-26 | Ritsumeikan | 微細粒子製造方法 |
| CA2299284C (en) * | 1997-08-05 | 2008-07-08 | Mfic Corporation | Multiple stream high pressure mixer/reactor |
| AU743440B2 (en) | 1997-12-17 | 2002-01-24 | Universidad De Sevilla | Device and method for creating aerosols for drug delivery |
| US6086376A (en) * | 1998-01-30 | 2000-07-11 | Rtp Pharma Inc. | Dry aerosol suspension of phospholipid-stabilized drug microparticles in a hydrofluoroalkane propellant |
| JP2934229B1 (ja) * | 1998-05-14 | 1999-08-16 | 清二 加川 | 固液混合流体の破砕・分散装置 |
| US8293277B2 (en) * | 1998-10-01 | 2012-10-23 | Alkermes Pharma Ireland Limited | Controlled-release nanoparticulate compositions |
| US6610317B2 (en) * | 1999-05-27 | 2003-08-26 | Acusphere, Inc. | Porous paclitaxel matrices and methods of manufacture thereof |
| DE10007816A1 (de) | 2000-02-21 | 2001-09-06 | Bayer Ag | Verfahren zur Herstellung von Nanosuspensionen |
| CA2407027C (en) * | 2000-04-20 | 2011-02-15 | Rtp Pharma Inc. | Improved water-insoluble drug particle process |
| DE60140625D1 (de) * | 2000-08-15 | 2010-01-07 | Univ Illinois | Verfahren zur herstellung von mikropartikeln |
| US6977085B2 (en) * | 2000-12-22 | 2005-12-20 | Baxter International Inc. | Method for preparing submicron suspensions with polymorph control |
| EP1642571A3 (en) * | 2000-12-22 | 2007-06-27 | Baxter International Inc. | Method for preparing submicron particle suspensions |
| US6869617B2 (en) * | 2000-12-22 | 2005-03-22 | Baxter International Inc. | Microprecipitation method for preparing submicron suspensions |
| US6884436B2 (en) * | 2000-12-22 | 2005-04-26 | Baxter International Inc. | Method for preparing submicron particle suspensions |
| JP2003001079A (ja) * | 2001-06-18 | 2003-01-07 | Karasawa Fine Ltd | 粒子微細化装置 |
| US7511079B2 (en) | 2003-03-24 | 2009-03-31 | Baxter International Inc. | Methods and apparatuses for the comminution and stabilization of small particles |
-
2004
- 2004-03-22 US US10/806,050 patent/US7511079B2/en not_active Expired - Fee Related
- 2004-03-24 BR BRPI0408707-0A patent/BRPI0408707A/pt not_active IP Right Cessation
- 2004-03-24 JP JP2006509324A patent/JP2006521396A/ja active Pending
- 2004-03-24 MX MXPA05010045A patent/MXPA05010045A/es unknown
- 2004-03-24 KR KR1020057017803A patent/KR20050115298A/ko not_active Ceased
- 2004-03-24 EP EP04758149A patent/EP1605915A2/en not_active Withdrawn
- 2004-03-24 CA CA002519536A patent/CA2519536A1/en not_active Abandoned
- 2004-03-24 WO PCT/US2004/009242 patent/WO2004084860A2/en not_active Ceased
- 2004-03-24 AU AU2004224307A patent/AU2004224307A1/en not_active Abandoned
-
2005
- 2005-10-24 NO NO20054908A patent/NO20054908L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| US20040266890A1 (en) | 2004-12-30 |
| CA2519536A1 (en) | 2004-10-07 |
| MXPA05010045A (es) | 2005-10-26 |
| AU2004224307A1 (en) | 2004-10-07 |
| KR20050115298A (ko) | 2005-12-07 |
| WO2004084860A2 (en) | 2004-10-07 |
| US7511079B2 (en) | 2009-03-31 |
| WO2004084860A3 (en) | 2005-03-24 |
| EP1605915A2 (en) | 2005-12-21 |
| NO20054908L (no) | 2005-12-21 |
| NO20054908D0 (no) | 2005-10-24 |
| JP2006521396A (ja) | 2006-09-21 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B08F | Application fees: application dismissed [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 6A E 7A ANUIDADES. |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2129 DE 25/10/2011. |