BRPI0408773A - embolização temporária usando-se polìmeros termossensìveis inverso - Google Patents

embolização temporária usando-se polìmeros termossensìveis inverso

Info

Publication number
BRPI0408773A
BRPI0408773A BRPI0408773-9A BRPI0408773A BRPI0408773A BR PI0408773 A BRPI0408773 A BR PI0408773A BR PI0408773 A BRPI0408773 A BR PI0408773A BR PI0408773 A BRPI0408773 A BR PI0408773A
Authority
BR
Brazil
Prior art keywords
embolization
inverse thermosensitive
inverse
composition
thermosensitive polymers
Prior art date
Application number
BRPI0408773-9A
Other languages
English (en)
Inventor
Alexander Schwarz
Jean Raymond
Original Assignee
Biosphere Medical Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biosphere Medical Inc filed Critical Biosphere Medical Inc
Publication of BRPI0408773A publication Critical patent/BRPI0408773A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/04—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
    • A61L24/046—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/765—Polymers containing oxygen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/001—Use of materials characterised by their function or physical properties
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/001—Use of materials characterised by their function or physical properties
    • A61L24/0015—Medicaments; Biocides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/001—Use of materials characterised by their function or physical properties
    • A61L24/0031—Hydrogels or hydrocolloids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/402—Anaestetics, analgesics, e.g. lidocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/404—Biocides, antimicrobial agents, antiseptic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/404—Biocides, antimicrobial agents, antiseptic agents
    • A61L2300/406—Antibiotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/404—Biocides, antimicrobial agents, antiseptic agents
    • A61L2300/408—Virucides, spermicides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/416—Anti-neoplastic or anti-proliferative or anti-restenosis or anti-angiogenic agents, e.g. paclitaxel, sirolimus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/44—Radioisotopes, radionuclides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/442—Colorants, dyes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00—Materials characterised by their function or physical properties
    • A61L2400/04—Materials for stopping bleeding
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00—Materials characterised by their function or physical properties
    • A61L2400/06—Flowable or injectable implant compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/36—Materials or treatment for tissue regeneration for embolization or occlusion, e.g. vaso-occlusive compositions or devices

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Surgery (AREA)
  • Materials Engineering (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Transplantation (AREA)
  • Vascular Medicine (AREA)
  • Neurosurgery (AREA)
  • Cardiology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Virology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Neurology (AREA)
  • Rheumatology (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Surgical Instruments (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

"EMBOLIZAçãO TEMPORORáRIA USANDO-SE POLìMEROS TERMOSSENSìVEIS INVERSO". Um aspecto da presente invenção refere-se a métodos de embolização de um sítio vascular em um mamífero compreendendo a introdução para dentro da vasculatura de um mamífero uma composição compreendendo um polímero termossensível inverso, em que os ditos géis de polímero de termossensível inverso na dita vasculatura, composição essa que pode ser injetada através de um pequeno cateter, e composições essas que se transformam em gel a ou abaixo da temperatura de corpo. Em certas concretizações dos métodos de embolização, a dita composição ulteriormente compreende uma molécula marcadora, tal como um corante, radiopaco, ou um composto visível por MRI.
BRPI0408773-9A 2003-03-24 2004-03-05 embolização temporária usando-se polìmeros termossensìveis inverso BRPI0408773A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US45714803P 2003-03-24 2003-03-24
PCT/US2004/006956 WO2004084703A2 (en) 2003-03-24 2004-03-05 Temporary embolization using inverse thermosensitive polymers

Publications (1)

Publication Number Publication Date
BRPI0408773A true BRPI0408773A (pt) 2006-03-28

Family

ID=33098204

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0408773-9A BRPI0408773A (pt) 2003-03-24 2004-03-05 embolização temporária usando-se polìmeros termossensìveis inverso

Country Status (11)

Country Link
US (5) US20050008610A1 (pt)
EP (2) EP2724719A1 (pt)
JP (5) JP4909071B2 (pt)
KR (2) KR101425385B1 (pt)
CN (3) CN1794980A (pt)
AU (1) AU2004224439B2 (pt)
BR (1) BRPI0408773A (pt)
CA (1) CA2519946C (pt)
HK (1) HK1197032A1 (pt)
MX (1) MXPA05010002A (pt)
WO (1) WO2004084703A2 (pt)

Families Citing this family (65)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE01918975T1 (de) 2000-03-24 2006-04-13 Biosphere Medical, Inc., Rockland Mikrokügelchen zur aktiven Embolisierung
US20040266983A1 (en) * 2000-08-17 2004-12-30 Reeve Lorraine E Purified polyoxyalkylene block copolymers
AU2004224439B2 (en) * 2003-03-24 2010-07-15 Genzyme Corporation Temporary embolization using inverse thermosensitive polymers
US7700086B2 (en) * 2003-11-06 2010-04-20 Pluromed, Inc. Internal clamp for surgical procedures
US20050228433A1 (en) * 2004-03-16 2005-10-13 Weenna Bucay-Couto In situ implant and method of forming same
US20060222596A1 (en) * 2005-04-01 2006-10-05 Trivascular, Inc. Non-degradable, low swelling, water soluble radiopaque hydrogel polymer
KR20140090270A (ko) 2005-05-09 2014-07-16 바이오스피어 메디칼 에스.에이. 마이크로스피어 및 비이온성 조영제를 사용하는 조성물 및 방법
US20060251581A1 (en) * 2005-05-09 2006-11-09 Mcintyre Jon T Method for treatment of uterine fibroid tumors
WO2008018892A2 (en) * 2005-12-22 2008-02-14 Pluromed, Inc. Methods and kits for treating lacerations and puncture wounds using inverse thermosensitive polymers
US8062282B2 (en) * 2006-02-13 2011-11-22 Fossa Medical, Inc. Methods and apparatus for temporarily occluding body openings
KR20160023926A (ko) * 2006-02-28 2016-03-03 벡톤 디킨슨 앤드 컴퍼니 카테테르 잠금을 위한 항미생물성 조성물 및 방법
JP2010500917A (ja) 2006-06-15 2010-01-14 マイクロベンション， インコーポレイテッド 膨張性ポリマーで構成される塞栓形成デバイス
US8197499B2 (en) 2006-06-21 2012-06-12 The Board Of Trustees Of The Leland Stanford Junior University Compositions and methods for joining non-conjoined lumens
CA2656179A1 (en) 2006-06-21 2007-12-27 The Board Of Trustees Of The Leland Stanford Junior University Compositions and methods for joining non-conjoined lumens
US8608760B2 (en) 2006-06-21 2013-12-17 The Board Of Trustees Of The Leland Stanford Junior University Compositions and methods for joining non-conjoined lumens
WO2008033728A2 (en) * 2006-09-11 2008-03-20 Pluromed, Inc. Atraumatic occlusion balloons and skirts, and methods of use thereof
JP2010512230A (ja) * 2006-12-11 2010-04-22 プルーロームド インコーポレイテッド 灌流臓器止血法
EP2125092A4 (en) * 2007-02-22 2012-03-14 Pluromed Inc USE OF REVERSIBLE HEAT-SENSITIVE POLYMERS FOR FLOW CONTROL OF A BIOLOGICAL LIQUID AFTER MEDICAL USE
WO2008112424A1 (en) * 2007-03-08 2008-09-18 Mayo Foundation For Medical Education And Research Assessing heart failure
US9987221B2 (en) * 2007-08-23 2018-06-05 Boston Scientific Scimed, Inc. Injectable hydrogel compositions
IL199781A0 (en) 2009-07-09 2010-05-17 Yohai Zorea Heat resistant probiotic compositions and healthy food comprising them
WO2009070793A1 (en) * 2007-11-29 2009-06-04 Pluromed, Inc. Endoscopic mucosal resectioning using purified inverse thermosensitive polymers
WO2009086206A2 (en) * 2007-12-20 2009-07-09 Synvascular, Inc. Compositions and methods for joining non-conjoined lumens
AU2008345590B2 (en) 2007-12-21 2014-10-30 Microvention, Inc. Hydrogel filaments for biomedical uses
JP2011513331A (ja) * 2008-02-29 2011-04-28 アレイ バイオファーマ、インコーポレイテッド ピラゾール［３，４−ｂ］ピリジンＲＡＦ阻害剤
CN106037857A (zh) * 2008-02-29 2016-10-26 普拉罗美德公司 通过加热热敏聚合物进行的局部栓塞
EP2254651A4 (en) * 2008-02-29 2013-03-06 Pluromed Inc LOCAL EMBOLIZATION USING THERMOSENSITIVE POLYMERS
US8563037B2 (en) * 2009-02-06 2013-10-22 Tautona Group, L.P. Compositions and methods for joining non-conjoined lumens
BRPI1014645B1 (pt) 2009-04-30 2020-07-07 Technip France método e sistema para compartilhar linhas de amarração
CN102791183B (zh) 2009-10-26 2015-07-08 微排放器公司 由可膨胀的聚合物构成的栓塞装置
US8840867B2 (en) * 2010-05-20 2014-09-23 Val-Chum Limited Partnership Embolizing sclerosing hydrogel
US9192746B2 (en) * 2010-06-07 2015-11-24 Cook Medical Technologies Llc Reperfusion catheter system
EP2603240B1 (en) * 2010-08-09 2019-11-20 Degama Smart Ltd. Probiotic liquid food products
CN102988274B (zh) * 2010-09-08 2015-01-28 上海市肿瘤研究所 用于治疗肿瘤的药物缓释血管栓塞凝胶剂及其制备方法
WO2012077038A1 (en) 2010-12-06 2012-06-14 Degama Berrier Ltd. Composition and method for improving stability and extending shelf life of probiotic bacteria and food products thereof
US9456823B2 (en) 2011-04-18 2016-10-04 Terumo Corporation Embolic devices
WO2013158781A1 (en) 2012-04-18 2013-10-24 Microvention, Inc. Embolic devices
WO2013164725A1 (en) 2012-05-02 2013-11-07 Koninklijke Philips N.V. Spectral ct visualization of imageable drug eluting beads
US10695440B2 (en) 2012-05-24 2020-06-30 Biosphere Medical, Inc. Biomaterials suitable for use as drug eluting, magnetic resonance imaging detectable implants for vascular occlusion
AU2013274199B2 (en) 2012-06-14 2016-08-11 Microvention, Inc. Polymeric treatment compositions
WO2014062696A1 (en) 2012-10-15 2014-04-24 Microvention, Inc. Polymeric treatment compositions
WO2014145397A1 (en) * 2013-03-15 2014-09-18 Herskovic Arnold M Device and method for delivering medicaments
US10543175B1 (en) 2013-05-17 2020-01-28 Degama Berrier Ltd. Film composition and methods for producing the same
JP6226126B2 (ja) * 2013-10-09 2017-11-08 国立大学法人滋賀医科大学 血管塞栓剤
ITMI20131924A1 (it) * 2013-11-20 2015-05-21 Cosmo Technologies Ltd Emulsions or microemulsions for use in endoscopic mucosal resectioning and/or endoscopic submucosal dissection emulsioni o microemulsioni per uso nella resezione mucosale endoscopica e/o dissezione submucosale endoscopica
WO2015153996A1 (en) 2014-04-03 2015-10-08 Micro Vention, Inc. Embolic devices
US10092663B2 (en) 2014-04-29 2018-10-09 Terumo Corporation Polymers
EP3137124B1 (en) 2014-04-29 2019-01-09 Microvention, Inc. Polymers including active agents
CN104353108B (zh) * 2014-09-29 2018-08-07 烟台益诺依生物医药科技有限公司 一种应用于血管吻合术或血管内闭塞术的注射剂
WO2016201250A1 (en) 2015-06-11 2016-12-15 Microvention, Inc. Expansile device for implantation
JP2018006072A (ja) * 2016-06-29 2018-01-11 オートモーティブエナジーサプライ株式会社 リチウムイオン二次電池用負極
US10368874B2 (en) 2016-08-26 2019-08-06 Microvention, Inc. Embolic compositions
DK3541442T3 (da) 2016-11-16 2022-03-14 Persica Pharmaceuticals Ltd Antibiotiske formuleringer mod lændesmerter
WO2018183624A1 (en) 2017-03-29 2018-10-04 The Regents Of The University Of Colorado, A Body Corporate Reverse thermal gels and their use as vascular embolic repair agents
JP7362598B2 (ja) 2017-10-09 2023-10-17 マイクロベンション インコーポレイテッド 放射性液体塞栓物質
DK3709970T3 (da) * 2017-11-16 2025-07-07 Persica Pharmaceuticals Ltd Linezolidformuleringer
US11638578B2 (en) 2017-11-28 2023-05-02 Pneumonix Medical, Inc. Apparatus and method to seal a tissue tract
EP3501496A1 (en) * 2017-12-22 2019-06-26 Cosmo Technologies Ltd. Liquid delivery composition
CN110215542A (zh) * 2018-03-02 2019-09-10 成都远睿生物技术有限公司 一种形成血管临时阻塞物的方法
US11207060B2 (en) 2018-03-16 2021-12-28 Critical Innovations, LLC Systems and methods relating to medical applications of synthetic polymer formulations
KR20220007680A (ko) * 2019-05-10 2022-01-18 인셉트, 엘엘씨 일시적 물질을 사용한 색전술
US20240316243A1 (en) * 2021-05-12 2024-09-26 Pneumonix Medical, Inc. Methods and material compositions for sealing a tract
US12410293B2 (en) 2022-11-07 2025-09-09 Critical Innovations Llc Systems and methods relating to medical applications of inverse thermosensitive polymer foam formulations
CN116966336B (zh) * 2023-08-17 2026-03-06 北京化工大学 一种温敏性止血凝胶的制备方法及产品和应用
WO2025204539A1 (ja) * 2024-03-27 2025-10-02 国立大学法人大阪大学 塞栓物質

Family Cites Families (77)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3889685A (en) * 1973-11-02 1975-06-17 Cutter Lab Tubular unit with vessel engaging cuff structure
US4188373A (en) 1976-02-26 1980-02-12 Cooper Laboratories, Inc. Clear, water-miscible, liquid pharmaceutical vehicles and compositions which gel at body temperature for drug delivery to mucous membranes
US4168708A (en) * 1977-04-20 1979-09-25 Medical Engineering Corp. Blood vessel occlusion means suitable for use in anastomosis
US4268495A (en) 1979-01-08 1981-05-19 Ethicon, Inc. Injectable embolization and occlusion solution
HU184722B (en) * 1980-02-18 1984-10-29 Laszlo Lazar Therapeutically suitable silicone rubber mixture and therapeuticaid
US4474751A (en) 1983-05-16 1984-10-02 Merck & Co., Inc. Ophthalmic drug delivery system utilizing thermosetting gels
US4478822A (en) 1983-05-16 1984-10-23 Merck & Co., Inc. Drug delivery system utilizing thermosetting gels
CA1225585A (en) * 1983-06-30 1987-08-18 Maria T. Litvinova Composition for embolization of blood vessels
US4705517A (en) * 1985-09-03 1987-11-10 Becton, Dickinson And Company Percutaneously deliverable intravascular occlusion prosthesis
US5567859A (en) 1991-03-19 1996-10-22 Cytrx Corporation Polyoxypropylene/polyoxyethylene copolymers with improved biological activity
US4795741A (en) * 1987-05-06 1989-01-03 Biomatrix, Inc. Compositions for therapeutic percutaneous embolization and the use thereof
US4819637A (en) * 1987-09-01 1989-04-11 Interventional Therapeutics Corporation System for artificial vessel embolization and devices for use therewith
US5843156A (en) * 1988-08-24 1998-12-01 Endoluminal Therapeutics, Inc. Local polymeric gel cellular therapy
US4946463A (en) * 1989-04-10 1990-08-07 Pioneering Technologies, Inc. Vessel occluder
ES2140408T3 (es) 1991-03-19 2000-03-01 Cytrx Corp Copolimeros de polioxipropileno/polioxietileno con actividad biologica mejorada.
US5696298A (en) 1991-03-19 1997-12-09 Cytrx Corporation Polyoxypropylene/polyoxyethylene copolymers with improved biological activity
JP3356447B2 (ja) * 1991-10-16 2002-12-16 テルモ株式会社 乾燥高分子ゲルからなる血管病変塞栓材料
US5470568A (en) * 1992-02-13 1995-11-28 Arch Development Corporation Methods and compositions of a polymer (poloxamer) for cell repair
US5605687A (en) 1992-05-15 1997-02-25 Arch Development Corporation Methods and compositions of a polymer (poloxamer) for repair of electrical injury
US5514379A (en) * 1992-08-07 1996-05-07 The General Hospital Corporation Hydrogel compositions and methods of use
US5443478A (en) * 1992-09-02 1995-08-22 Board Of Regents, The University Of Texas System Multi-element intravascular occlusion device
WO1994006460A1 (en) * 1992-09-21 1994-03-31 Vitaphore Corporation Embolization plugs for blood vessels
US5382260A (en) * 1992-10-30 1995-01-17 Interventional Therapeutics Corp. Embolization device and apparatus including an introducer cartridge and method for delivering the same
EP0724888B1 (en) 1993-09-16 2003-05-21 Ogita Biomaterial Laboratories Co. Ltd. Wound covering material and wound covering composition
WO1995024160A1 (en) * 1994-03-08 1995-09-14 Cardima, Inc. Intravascular rf occlusion catheter
JP2535785B2 (ja) * 1994-06-03 1996-09-18 工業技術院長 血管塞栓剤
US5725552A (en) * 1994-07-08 1998-03-10 Aga Medical Corporation Percutaneous catheter directed intravascular occlusion devices
EP1221307B1 (en) * 1994-07-08 2010-02-17 ev3 Inc. System for performing an intravascular procedure
US6123715A (en) * 1994-07-08 2000-09-26 Amplatz; Curtis Method of forming medical devices; intravascular occlusion devices
US5614204A (en) * 1995-01-23 1997-03-25 The Regents Of The University Of California Angiographic vascular occlusion agents and a method for hemostatic occlusion
US5939485A (en) * 1995-06-19 1999-08-17 Medlogic Global Corporation Responsive polymer networks and methods of their use
WO1997005185A2 (en) * 1995-07-28 1997-02-13 Focal, Inc. Multiblock biodegradable hydrogels for use as controlled release agents for drugs delivery and tissue treatment agents
KR100210509B1 (ko) 1996-01-10 1999-07-15 성재갑 지속성 동물 성장 호르몬 제형 및 이의 제조 방법
US20020077461A1 (en) 1996-04-24 2002-06-20 Soren Bjorn Pharmaceutical formulation
DE69726725T2 (de) * 1996-04-26 2004-10-14 Medtronic, Inc., Minneapolis Intravaskuläre balloneinrichtung und gerät zum durchstechen einer gefässwand
US5695480A (en) * 1996-07-29 1997-12-09 Micro Therapeutics, Inc. Embolizing compositions
US5823198A (en) * 1996-07-31 1998-10-20 Micro Therapeutics, Inc. Method and apparatus for intravasculer embolization
US5800711A (en) 1996-10-18 1998-09-01 Mdv Technologies, Inc. Process for the fractionation of polyoxyalkylene block copolymers
US6495579B1 (en) * 1996-12-02 2002-12-17 Angiotech Pharmaceuticals, Inc. Method for treating multiple sclerosis
US6030634A (en) * 1996-12-20 2000-02-29 The Chinese University Of Hong Kong Polymer gel composition and uses therefor
US6120751A (en) * 1997-03-21 2000-09-19 Imarx Pharmaceutical Corp. Charged lipids and uses for the same
US6015424A (en) * 1998-04-28 2000-01-18 Microvention, Inc. Apparatus and method for vascular embolization
US6113629A (en) * 1998-05-01 2000-09-05 Micrus Corporation Hydrogel for the therapeutic treatment of aneurysms
US6165193A (en) * 1998-07-06 2000-12-26 Microvention, Inc. Vascular embolization with an expansible implant
US6525100B1 (en) * 1998-08-03 2003-02-25 W. Jerry Easterling Composition and method for treating peyronie's disease and related fibrotic tissue disorders
EP1109563A4 (en) 1998-08-04 2009-07-22 Madash Llp AT THE END MODIFIED HYDROGELE WITH TEMPERATURE DEPENDENT FEATURES
FR2784580B1 (fr) * 1998-10-16 2004-06-25 Biosepra Inc Microspheres de polyvinyl-alcool et procedes de fabrication de celles-ci
US6333194B1 (en) 1999-01-19 2001-12-25 The Children's Hospital Of Philadelphia Hydrogel compositions for controlled delivery of virus vectors and methods of use thereof
WO2000045868A1 (en) * 1999-02-05 2000-08-10 The Regents Of The University Of California Thermo-reversible polymer for intralumenal implant
US6428558B1 (en) * 1999-03-10 2002-08-06 Cordis Corporation Aneurysm embolization device
US6613074B1 (en) * 1999-03-10 2003-09-02 Cordis Corporation Endovascular aneurysm embolization device
US6379329B1 (en) * 1999-06-02 2002-04-30 Cordis Neurovascular, Inc. Detachable balloon embolization device and method
US6312421B1 (en) * 1999-07-23 2001-11-06 Neurovasx, Inc. Aneurysm embolization material and device
WO2001030411A1 (fr) * 1999-10-26 2001-05-03 Kaken Pharmaceutical Co., Ltd. Materiau de traitement d'embolie vasculaire a base d'hydrogel et therapie correspondante
EP1263803B1 (en) * 2000-03-13 2007-09-19 BioCure, Inc. Embolic compositions
DE01918975T1 (de) * 2000-03-24 2006-04-13 Biosphere Medical, Inc., Rockland Mikrokügelchen zur aktiven Embolisierung
ES2391763T3 (es) * 2000-04-07 2012-11-29 Collagen Matrix, Inc. Dispositivo de embolización
CN1124858C (zh) * 2000-05-12 2003-10-22 苏州医学院附属第一医院 一种血管栓塞剂及其制备工艺
JP2001329183A (ja) * 2000-05-22 2001-11-27 Yuichi Mori ゲル化性組成物
US6355275B1 (en) * 2000-06-23 2002-03-12 Carbon Medical Technologies, Inc. Embolization using carbon coated microparticles
US6660247B1 (en) * 2000-06-23 2003-12-09 Battelle Memorial Institute Multiple stimulus reversible hydrogels
US6761824B2 (en) 2000-08-17 2004-07-13 Reeve Lorraine E Process for the fractionation of polymers
US6686203B2 (en) * 2000-09-11 2004-02-03 William J. Calvo Histologic visualization of cyanoacrylate embolization
US6554849B1 (en) * 2000-09-11 2003-04-29 Cordis Corporation Intravascular embolization device
US6723108B1 (en) * 2000-09-18 2004-04-20 Cordis Neurovascular, Inc Foam matrix embolization device
US6485709B2 (en) * 2001-01-23 2002-11-26 Addent Inc. Dental bleaching gel composition, activator system and method for activating a dental bleaching gel
US6786887B2 (en) * 2001-01-26 2004-09-07 Scimed Life Systems, Inc. Intravascular occlusion balloon catheter
US6862890B2 (en) * 2001-01-30 2005-03-08 Board Of Regents, University Of Texas System Process for production of nanoparticles and microparticles by spray freezing into liquid
WO2002087416A2 (en) * 2001-04-26 2002-11-07 Porter Christopher H Method and apparatus for delivering materials to the body
US7072312B2 (en) * 2001-05-14 2006-07-04 Interdigital Technology Corporation Assigning physical channels of a new user service in a hybrid time division multiple access/code division multiple access communication system
US6692510B2 (en) * 2001-06-14 2004-02-17 Cordis Neurovascular, Inc. Aneurysm embolization device and deployment system
US7094369B2 (en) * 2002-03-29 2006-08-22 Scimed Life Systems, Inc. Processes for manufacturing polymeric microspheres
US20030199887A1 (en) * 2002-04-23 2003-10-23 David Ferrera Filamentous embolization device and method of use
US7838699B2 (en) * 2002-05-08 2010-11-23 Biosphere Medical Embolization using degradable crosslinked hydrogels
AU2004224439B2 (en) * 2003-03-24 2010-07-15 Genzyme Corporation Temporary embolization using inverse thermosensitive polymers
US7700086B2 (en) * 2003-11-06 2010-04-20 Pluromed, Inc. Internal clamp for surgical procedures
US20050255091A1 (en) * 2004-05-14 2005-11-17 Loomis Gary L Hydrogels for biomedical applications

Also Published As

Publication number Publication date
WO2004084703A2 (en) 2004-10-07
US20170290948A1 (en) 2017-10-12
CA2519946A1 (en) 2004-10-07
JP2014039882A (ja) 2014-03-06
HK1197032A1 (en) 2015-01-02
KR20120087912A (ko) 2012-08-07
US20050008610A1 (en) 2005-01-13
JP2010246953A (ja) 2010-11-04
US20130195753A1 (en) 2013-08-01
US20110076231A1 (en) 2011-03-31
KR101425385B1 (ko) 2014-07-31
CN106215226A (zh) 2016-12-14
EP1605922A4 (en) 2011-03-16
CA2519946C (en) 2011-09-06
JP4909071B2 (ja) 2012-04-04
US20150010471A1 (en) 2015-01-08
AU2004224439B2 (en) 2010-07-15
MXPA05010002A (es) 2006-03-10
CN102813967A (zh) 2012-12-12
WO2004084703A3 (en) 2005-05-12
JP2017131792A (ja) 2017-08-03
JP2006521177A (ja) 2006-09-21
KR20060023112A (ko) 2006-03-13
KR101198550B1 (ko) 2012-11-06
EP2724719A1 (en) 2014-04-30
JP2016093659A (ja) 2016-05-26
EP1605922A2 (en) 2005-12-21
CN1794980A (zh) 2006-06-28
AU2004224439A1 (en) 2004-10-07

Similar Documents

Publication Publication Date Title
BRPI0408773A (pt) embolização temporária usando-se polìmeros termossensìveis inverso
BRPI0519748A2 (pt) preparaÇço de curativo para resfriamento tàpico
BRPI0508233A (pt) derivados de isoquinolina e métodos para emprego destes
BR0315304A (pt) Formulações com depósito para liberação controlada
NO20033178D0 (no) Kateterinjiserbare depotforbindelser og deres anvendelse
NO20033177D0 (no) Injiserbare depotforbindelser og deres anvendelse
ATE220894T1 (de) Zusammensetzung für lokale freigabe von zytostatika
BRPI0407262A (pt) Derivados de malonamida como inibidores gama-secretase
BRPI0514841A (pt) inibidores de piridila da sinalização de hedgehog, processo de preparação dos mesmos e composição compreendendo os referidos inibidores
BRPI0714899A2 (pt) composiÇÕes para o tratamento do cabelo e mÉtodo para o tratamento do cabelo humano
BRPI0512535A (pt) compostos de piperidinas n-substituìdas, suas composições e métodos de modulações
CO5580737A2 (es) Composiciones y metodos para administrar unguentos antibacterianos, antimicoticos y antivirales a las cavidades bucal, nasal o vaginal
BRPI0416032A (pt) excipientes em veìculos de distribuição de fármacos
BRPI0818893B8 (pt) compostos de tropano, suas composições farmacêuticas, seus usos e método in vitro de inibição de hsp90 em uma célula
BR0011256A (pt) Componente ativo antiperspirante, veìculo lìquido e estruturante ou espessante para o veìculo, processo para a produção de um bastão antiperspirante, e, método para prevenir ou reduzir perspiração sobre pele humana
BRPI0412581A (pt) formulação dispersável de um agente antiinflamatório
BR112012002709A2 (pt) formulações de liberação controlada de muteínas de lipocalina
NO20074737L (no) Isokinolinforbindelser og fremgangsmater for anvendelse derav
BR112012006756A2 (pt) revestimentos para aplicação na superfície da pele
CN106619489A (zh) 一种用于皮肤损伤的温敏型凝胶剂及其制备方法
ECSP055710A (es) Composición antihelmíntica e inyectable mejoradora de crecimiento
BRPI0516077A (pt) composições antimicrobianas compreendendo um agente natural selecionado de ácido gálico, eucalipotol, naringina, um composto de ácido jasmÈnico e qualquer combinação destes
PE20020945A1 (es) Composiciones parasiticidas para el control de ectoparasitos
MX2007005509A (es) Composicion y viscoelastica de polimero natural triple.
EP1548004A4 (en) LOW MOLECULAR BIOLOGICAL DERIVATIVES

Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]

Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI

B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]