BRPI0409329A - processo para fabricar pelìculas de gel termorreversìveis, homogêneas, pelìcula homogênea, termorreversìvel, de sólidos altos, umidade baixa, processo para fabricar cápsulas moles, cápsulas moles, processo para fabricar uma forma de dosagem sólida, forma sólida, processo para preparar uma sistema de liberação de pelìcula de gel homogênea, e, sistema de liberação - Google Patents

processo para fabricar pelìculas de gel termorreversìveis, homogêneas, pelìcula homogênea, termorreversìvel, de sólidos altos, umidade baixa, processo para fabricar cápsulas moles, cápsulas moles, processo para fabricar uma forma de dosagem sólida, forma sólida, processo para preparar uma sistema de liberação de pelìcula de gel homogênea, e, sistema de liberação

Info

Publication number
BRPI0409329A
BRPI0409329A BRPI0409329-1A BRPI0409329A BRPI0409329A BR PI0409329 A BRPI0409329 A BR PI0409329A BR PI0409329 A BRPI0409329 A BR PI0409329A BR PI0409329 A BRPI0409329 A BR PI0409329A
Authority
BR
Brazil
Prior art keywords
homogeneous
gel
thermo
release system
reversible
Prior art date
Application number
BRPI0409329-1A
Other languages
English (en)
Inventor
Arthur D Ballard
Christopher J Sewall
James J Modliszewski
William R Blakemore
Peter J Riley
Original Assignee
Fmc Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fmc Corp filed Critical Fmc Corp
Publication of BRPI0409329A publication Critical patent/BRPI0409329A/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L29/00Foods or foodstuffs containing additives; Preparation or treatment thereof
    • A23L29/20Foods or foodstuffs containing additives; Preparation or treatment thereof containing gelling or thickening agents
    • A23L29/206Foods or foodstuffs containing additives; Preparation or treatment thereof containing gelling or thickening agents of vegetable origin
    • A23L29/238Foods or foodstuffs containing additives; Preparation or treatment thereof containing gelling or thickening agents of vegetable origin from seeds, e.g. locust bean gum or guar gum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/02Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/04Dispersions; Emulsions
    • A61K8/042Gels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/02Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/11Encapsulated compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • A61K8/737Galactomannans, e.g. guar; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7007Drug-containing films, membranes or sheets
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Birds (AREA)
  • Molecular Biology (AREA)
  • Dispersion Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Inorganic Chemistry (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Food Science & Technology (AREA)
  • Nutrition Science (AREA)
  • Dermatology (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Polymers & Plastics (AREA)
  • Medicinal Preparation (AREA)
  • Manufacture Of Macromolecular Shaped Articles (AREA)
  • Jellies, Jams, And Syrups (AREA)
  • General Preparation And Processing Of Foods (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Cosmetics (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Extrusion Moulding Of Plastics Or The Like (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Seasonings (AREA)
  • Processing And Handling Of Plastics And Other Materials For Molding In General (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)

Abstract

"PROCESSO PARA FABRICAR PELìCULAS DE GEL TERMORREVERSìVEIS, HOMOGêNEAS, PELìCULA HOMOGêNEA, TERMORREVERSìVEL DE SóLIDOS ALTOS UMIDADE BAIXA PROCESSO PARA FABRICAR CáPSULAS MOLES, CáPSULAS MOLES, PROCESSO PARA FABRICAR UMA FORMA DE DOSAGEM SóLIDA, FORMA SóLIDA, PROCESSO PARA PREPARAR UMA SISTEMA DE LIBERAçãO DE PELìCULA DE GEL HOMOGêNEA, E, SISTEMA DE LIBERAçãO". A presente invenção está direcionada a um processo para fabricar películas de gel termorreversíveis, homogêneas que compreendem as etapas de: (i) aquecer, hidratar, misturar, solubilizar e, opcionalmente, desaerar uma composição que forma película de sólidos altos, umidade baixa em um aparelho que forneça cisalhamento, temperatura e tempo de residência suficientes para formar uma composição homogênea fundida, em que a temperatura está na ou acima da temperatura de solubilização da dita composição; (ii) alimentar a composição fundida em pelo menos um de um misturador, bomba ou desvolatilizador; e (iii) esfriar a composição fundida homogênea na ou abaixo da sua temperatura de formação de gel para formar as ditas películas de gel. A presente invenção também está direcionada aos vários produtos fabricados a partir de tais películas, tais como as próprias películas de gel, cápsulas moles, formas de dosagem sólidas e sistemas de liberação.
BRPI0409329-1A 2003-04-14 2004-04-14 processo para fabricar pelìculas de gel termorreversìveis, homogêneas, pelìcula homogênea, termorreversìvel, de sólidos altos, umidade baixa, processo para fabricar cápsulas moles, cápsulas moles, processo para fabricar uma forma de dosagem sólida, forma sólida, processo para preparar uma sistema de liberação de pelìcula de gel homogênea, e, sistema de liberação BRPI0409329A (pt)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US46279303P 2003-04-14 2003-04-14
US46261703P 2003-04-14 2003-04-14
US46279203P 2003-04-14 2003-04-14
US46272103P 2003-04-14 2003-04-14
US46275803P 2003-04-14 2003-04-14
US46278503P 2003-04-14 2003-04-14
US46279403P 2003-04-14 2003-04-14
US46278303P 2003-04-14 2003-04-14
PCT/US2004/011906 WO2004091537A2 (en) 2003-04-14 2004-04-14 Process for making gel films

Publications (1)

Publication Number Publication Date
BRPI0409329A true BRPI0409329A (pt) 2006-04-25

Family

ID=33304300

Family Applications (7)

Application Number Title Priority Date Filing Date
BRPI0409345-3A BRPI0409345A (pt) 2003-04-14 2004-04-14 sistema de liberação, pelìcula de sistema de liberação, e, processo para preparar o sistema de pelìcula de gel homogêneo
BRPI0409343-7A BRPI0409343A (pt) 2003-04-14 2004-04-14 gel termorreversìvel, homogêneo, pelìcula, produto comestìvel, cápsulas moles, forma sólida, cápsulas duras, processos para fabricar os géis e as cápsulas moles, processo para diminuir a temperatura de formação de gel de uma composição, e, sistema de liberação
BRPI0409329-1A BRPI0409329A (pt) 2003-04-14 2004-04-14 processo para fabricar pelìculas de gel termorreversìveis, homogêneas, pelìcula homogênea, termorreversìvel, de sólidos altos, umidade baixa, processo para fabricar cápsulas moles, cápsulas moles, processo para fabricar uma forma de dosagem sólida, forma sólida, processo para preparar uma sistema de liberação de pelìcula de gel homogênea, e, sistema de liberação
BRPI0409336-4A BRPI0409336A (pt) 2003-04-14 2004-04-14 sistema de liberação compreendendo uma pelìcula de gel termorreversìvel, homogênea, pelìcula de sistema de liberação, e, processo para preparar o sistema de liberação da mesma
BRPI0409357A BRPI0409357B8 (pt) 2003-04-14 2004-04-14 película de gel termorreversível homogênea, processo para fabricar as películas de gel, cápsulas moles, processo para fabricar as cápsulas moles, e, forma sólida
BRPI0409342-9A BRPI0409342A (pt) 2003-04-14 2004-04-14 pelìcula de gel termorreversìvel homogênea, cápsulas moles, processos para fabricar as pelìculas de gel e para fabricar cápsulas moles contendo as pelìculas de gel, e, forma sólida
BRPI0409334-8A BRPI0409334A (pt) 2003-04-14 2004-04-14 pelìcula de gel termorreversìvel, homogênea, cápsulas moles, processos para fabricar as pelìculas de gel e cápsulas moles, e, forma sólida

Family Applications Before (2)

Application Number Title Priority Date Filing Date
BRPI0409345-3A BRPI0409345A (pt) 2003-04-14 2004-04-14 sistema de liberação, pelìcula de sistema de liberação, e, processo para preparar o sistema de pelìcula de gel homogêneo
BRPI0409343-7A BRPI0409343A (pt) 2003-04-14 2004-04-14 gel termorreversìvel, homogêneo, pelìcula, produto comestìvel, cápsulas moles, forma sólida, cápsulas duras, processos para fabricar os géis e as cápsulas moles, processo para diminuir a temperatura de formação de gel de uma composição, e, sistema de liberação

Family Applications After (4)

Application Number Title Priority Date Filing Date
BRPI0409336-4A BRPI0409336A (pt) 2003-04-14 2004-04-14 sistema de liberação compreendendo uma pelìcula de gel termorreversìvel, homogênea, pelìcula de sistema de liberação, e, processo para preparar o sistema de liberação da mesma
BRPI0409357A BRPI0409357B8 (pt) 2003-04-14 2004-04-14 película de gel termorreversível homogênea, processo para fabricar as películas de gel, cápsulas moles, processo para fabricar as cápsulas moles, e, forma sólida
BRPI0409342-9A BRPI0409342A (pt) 2003-04-14 2004-04-14 pelìcula de gel termorreversìvel homogênea, cápsulas moles, processos para fabricar as pelìculas de gel e para fabricar cápsulas moles contendo as pelìculas de gel, e, forma sólida
BRPI0409334-8A BRPI0409334A (pt) 2003-04-14 2004-04-14 pelìcula de gel termorreversìvel, homogênea, cápsulas moles, processos para fabricar as pelìculas de gel e cápsulas moles, e, forma sólida

Country Status (10)

Country Link
US (3) US7807194B2 (pt)
EP (8) EP1620114A2 (pt)
JP (8) JP2007525451A (pt)
KR (4) KR20060011953A (pt)
BR (7) BRPI0409345A (pt)
CA (5) CA2522295C (pt)
IL (1) IL171291A (pt)
MX (4) MXPA05011028A (pt)
PL (1) PL1628643T3 (pt)
WO (9) WO2004091529A2 (pt)

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