BRPI0409948A - composições de spex e processos de uso - Google Patents

composições de spex e processos de uso

Info

Publication number
BRPI0409948A
BRPI0409948A BRPI0409948-6A BRPI0409948A BRPI0409948A BR PI0409948 A BRPI0409948 A BR PI0409948A BR PI0409948 A BRPI0409948 A BR PI0409948A BR PI0409948 A BRPI0409948 A BR PI0409948A
Authority
BR
Brazil
Prior art keywords
spex
polypeptides
compositions
polynucleotides
compounds
Prior art date
Application number
BRPI0409948-6A
Other languages
English (en)
Inventor
Jonathan Kaye
Beverley Wilkinson
Original Assignee
Novartis Ag
Scripps Research Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag, Scripps Research Inst filed Critical Novartis Ag
Publication of BRPI0409948A publication Critical patent/BRPI0409948A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

"COMPOSIçõES DE SPEX E PROCESSOS DE USO". A presente invenção fornece novos polipeptídeos e outros fatores identificados como sendo expressos no tecido do baço e relacionados com a atividade de linfócitos e com a resposta imunológica. Estes compostos são referidos aqui como compostos SPEX. São fornecidos homólogos humanos e murinos de polipeptídeos e polinucleotídeos SPEX incluindo dois alelos murinos. A invenção fornece ainda polinucleotídeos que codificam os polipeptídeos e as seqüências de ácidos nucléicos complementares dos mesmos. Também são fornecidos imunógenos, vetores de expressão e anticorpos relacionados com os polipeptídeos e os polinucleotídeos SPEX. A presente invenção divulga o uso de anticorpos anti-SPEX na regulação da atividade de linfócitos e na regulação da resposta imunológica.
BRPI0409948-6A 2003-04-30 2004-04-29 composições de spex e processos de uso BRPI0409948A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US46720603P 2003-04-30 2003-04-30
PCT/EP2004/004562 WO2004096976A2 (en) 2003-04-30 2004-04-29 Spex compositions and methods of use

Publications (1)

Publication Number Publication Date
BRPI0409948A true BRPI0409948A (pt) 2006-04-25

Family

ID=33418441

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0409948-6A BRPI0409948A (pt) 2003-04-30 2004-04-29 composições de spex e processos de uso

Country Status (9)

Country Link
US (1) US20040248257A1 (pt)
EP (1) EP1622935A2 (pt)
JP (1) JP2006524489A (pt)
CN (1) CN1795205A (pt)
AU (1) AU2004234532A1 (pt)
BR (1) BRPI0409948A (pt)
CA (1) CA2523025A1 (pt)
MX (1) MXPA05011595A (pt)
WO (1) WO2004096976A2 (pt)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1539218A4 (en) * 2002-06-20 2007-08-22 Univ California COMPOSITIONS AND METHODS FOR MODULATING LYMPHOCYTE ACTIVITY
US8546541B2 (en) 2002-06-20 2013-10-01 Washington University Compositions and methods for modulating lymphocyte activity
WO2005030119A2 (en) * 2003-04-11 2005-04-07 Allergan, Inc. Botulinum toxin a peptides and methods of predicting and reducing immunoresistance to botulinum toxin therapy
US8188232B1 (en) 2004-11-15 2012-05-29 Washington University In St. Louis Compositions and methods for modulating lymphocyte activity
US8349320B2 (en) 2004-12-09 2013-01-08 La Jolla Institute For Allergy And Immunology Compositions and methods for modulating responses mediated or associated with BTLA activity
EP1833848A2 (en) * 2004-12-09 2007-09-19 Lajolla Institute for Allergy and Immunology Novel tnf receptor regulatory domain
US8303952B2 (en) 2009-06-08 2012-11-06 Washington University Methods for inducing in vivo tolerance
CN112877353B (zh) * 2021-01-19 2023-01-17 东北林业大学 一种表达载体及其制备方法和应用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2577799A (en) * 1998-02-09 1999-08-23 Human Genome Sciences, Inc. 45 human secreted proteins
US6783961B1 (en) * 1999-02-26 2004-08-31 Genset S.A. Expressed sequence tags and encoded human proteins
JP2004533222A (ja) * 2001-03-12 2004-11-04 インサイト・ゲノミックス・インコーポレイテッド 免疫グロブリンスーパーファミリータンパク質
US20040097711A1 (en) * 2002-03-12 2004-05-20 Henry Yue Immunoglobulin superfamily proteins
EP1539218A4 (en) * 2002-06-20 2007-08-22 Univ California COMPOSITIONS AND METHODS FOR MODULATING LYMPHOCYTE ACTIVITY
EP1560593B1 (en) * 2002-10-25 2016-04-20 Genentech, Inc. Novel composition and methods for the treatment of immune related diseases

Also Published As

Publication number Publication date
AU2004234532A1 (en) 2004-11-11
CN1795205A (zh) 2006-06-28
WO2004096976A3 (en) 2005-04-07
US20040248257A1 (en) 2004-12-09
WO2004096976A2 (en) 2004-11-11
EP1622935A2 (en) 2006-02-08
CA2523025A1 (en) 2004-11-11
MXPA05011595A (es) 2005-12-15
JP2006524489A (ja) 2006-11-02

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Legal Events

Date Code Title Description
B08F Application fees: application dismissed [chapter 8.6 patent gazette]

Free format text: REFERENTE A 6A E 7A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2129 DE 25/10/2011.