BRPI0410021A - preparação farmacêutica sólida, que contém sais levotiroxina e/ou liotironina como substáncia ativa - Google Patents
preparação farmacêutica sólida, que contém sais levotiroxina e/ou liotironina como substáncia ativaInfo
- Publication number
- BRPI0410021A BRPI0410021A BRPI0410021-2A BRPI0410021A BRPI0410021A BR PI0410021 A BRPI0410021 A BR PI0410021A BR PI0410021 A BRPI0410021 A BR PI0410021A BR PI0410021 A BRPI0410021 A BR PI0410021A
- Authority
- BR
- Brazil
- Prior art keywords
- pharmaceutical preparation
- salts
- preparation containing
- lyothyronine
- solid pharmaceutical
- Prior art date
Links
- 239000000825 pharmaceutical preparation Substances 0.000 title abstract 3
- XUIIKFGFIJCVMT-LBPRGKRZSA-N L-thyroxine Chemical compound IC1=CC(C[C@H]([NH3+])C([O-])=O)=CC(I)=C1OC1=CC(I)=C(O)C(I)=C1 XUIIKFGFIJCVMT-LBPRGKRZSA-N 0.000 title abstract 2
- AUYYCJSJGJYCDS-LBPRGKRZSA-N Thyrolar Chemical class IC1=CC(C[C@H](N)C(O)=O)=CC(I)=C1OC1=CC=C(O)C(I)=C1 AUYYCJSJGJYCDS-LBPRGKRZSA-N 0.000 title abstract 2
- 239000013543 active substance Substances 0.000 title abstract 2
- 229950008325 levothyroxine Drugs 0.000 title abstract 2
- 239000007787 solid Substances 0.000 title abstract 2
- XUIIKFGFIJCVMT-UHFFFAOYSA-N thyroxine-binding globulin Natural products IC1=CC(CC([NH3+])C([O-])=O)=CC(I)=C1OC1=CC(I)=C(O)C(I)=C1 XUIIKFGFIJCVMT-UHFFFAOYSA-N 0.000 title abstract 2
- 150000003839 salts Chemical class 0.000 abstract 1
- 229940035722 triiodothyronine Drugs 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
- A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/14—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
"PREPARAçãO FARMACêUTICA SóLIDA, QUE CONTéM SAIS LEVOTIROXINA E/OU LIOTIRONINA COMO SUBSTáNCIA ATIVA". Em uma preparação farmacêutica, que contém sais solúveis em água de levotiroxina e/ou liotironina como substância ativa, a atividade de água da preparação farmacêutica, medida à temperatura ambiente, está ajustada para valores abaixo de 0,4, preferivelmente, 0,1 a 0,3.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AT6672003 | 2003-05-02 | ||
| PCT/AT2004/000150 WO2004096177A1 (de) | 2003-05-02 | 2004-05-03 | Feste pharmazeutische zubereitung enthaltend levothyroxin- und/oder liothyroninsalze |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0410021A true BRPI0410021A (pt) | 2006-04-25 |
Family
ID=33314944
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0410021-2A BRPI0410021A (pt) | 2003-05-02 | 2004-05-03 | preparação farmacêutica sólida, que contém sais levotiroxina e/ou liotironina como substáncia ativa |
Country Status (13)
| Country | Link |
|---|---|
| EP (1) | EP1622587B1 (pt) |
| JP (1) | JP5414146B2 (pt) |
| AT (1) | ATE465718T1 (pt) |
| AU (1) | AU2004234176B2 (pt) |
| BR (1) | BRPI0410021A (pt) |
| CA (1) | CA2523079C (pt) |
| DE (1) | DE502004011103D1 (pt) |
| DK (1) | DK1622587T3 (pt) |
| ES (1) | ES2344294T3 (pt) |
| PT (1) | PT1622587E (pt) |
| RU (1) | RU2361573C2 (pt) |
| WO (1) | WO2004096177A1 (pt) |
| ZA (1) | ZA200509026B (pt) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ITMI20022394A1 (it) | 2002-11-13 | 2004-05-14 | Bracco Spa | Uso di triiodotironina 3-solfato come farmaco ad attivita' tireomimetica e relative formulazioni farmaceutiche. |
| ITMI20110713A1 (it) | 2011-04-29 | 2012-10-30 | Bracco Imaging Spa | Processo per la preparazione di un derivato solfatato di3,5-diiodo-o-[3-iodofenil]-l-tirosina |
| FR2897267A1 (fr) * | 2006-02-16 | 2007-08-17 | Flamel Technologies Sa | Formes pharmaceutiques multimicroparticulaires pour administration per os |
| JP5600058B2 (ja) * | 2007-04-11 | 2014-10-01 | ファーマシューティカル プロダクションズ, インコーポレイテッド | メラトニンタブレットならびに調剤及び使用方法 |
| NO2885005T3 (pt) | 2012-08-20 | 2018-02-24 |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5225204A (en) * | 1991-11-05 | 1993-07-06 | Chen Jivn Ren | Stable dosage of levothyroxine sodium and process of production |
| DE4413350A1 (de) * | 1994-04-18 | 1995-10-19 | Basf Ag | Retard-Matrixpellets und Verfahren zu ihrer Herstellung |
| DE19541128C2 (de) * | 1995-10-27 | 1997-11-27 | Henning Berlin Gmbh & Co | Stabilisierte schilddrüsenhormonhaltige Arzneimittel |
| US5635209A (en) * | 1995-10-31 | 1997-06-03 | Vintage Pharmaceuticals, Inc. | Stabilized composition of levothyroxine sodium medication and method for its production |
| US5955105A (en) * | 1995-11-14 | 1999-09-21 | Knoll Pharmaceutical Company | Stabilized thyroid hormone preparations and methods of making same |
| JP2001114712A (ja) * | 1996-04-16 | 2001-04-24 | Takeda Chem Ind Ltd | D−マンニトールおよびその製造法 |
| DE19653410A1 (de) * | 1996-12-20 | 1998-06-25 | Basf Ag | Verwendung von Carotinoid-Solubilisaten zum Färben von Lebensmitteln und pharmazeutischen Zubereitungen |
| CN1242705A (zh) * | 1997-11-17 | 2000-01-26 | 吉斯特-布罗卡迪斯有限公司 | 含有棒酸盐和一种或多种赋型剂的颗粒剂 |
| JP3274416B2 (ja) * | 1998-05-29 | 2002-04-15 | 佐藤製薬株式会社 | 口腔内崩壊性粒状製剤 |
| FR2781793B1 (fr) | 1998-08-03 | 2001-07-20 | Prographarm Lab | Procede de fabrication de granules de gabapentine enrobes |
| JP2000060535A (ja) * | 1998-08-21 | 2000-02-29 | Kyowa Hakko Kogyo Co Ltd | 微生物菌体の保存方法 |
| JP3491887B2 (ja) * | 1999-04-28 | 2004-01-26 | フロイント産業株式会社 | 糖アルコール造粒物集合体の製法 |
| GB9919487D0 (en) * | 1999-08-17 | 1999-10-20 | Nestle Sa | Moulded onfectionery product comprising vegetables |
| JP4677084B2 (ja) * | 1999-09-30 | 2011-04-27 | 武田薬品工業株式会社 | 塩酸ブロムヘキシンを含有する固形製剤 |
| US6399101B1 (en) * | 2000-03-30 | 2002-06-04 | Mova Pharmaceutical Corp. | Stable thyroid hormone preparations and method of making same |
| IL153111A0 (en) * | 2000-06-30 | 2003-06-24 | Glaxo Group Ltd | Quinazoline ditosylate salt compounds |
| ES2174734B1 (es) * | 2000-11-03 | 2003-10-01 | Belmac S A Lab | Nueva formulacion galenica de paracetamol dispersable y soluble, procedimiento para su preparacion y aplicaciones. |
| BR0207297A (pt) * | 2001-02-15 | 2005-04-19 | King Pharmaceuticals Inc | Composição farmacêutica em forma sólida e método de preparar uma forma de dosagem sólida de um ingrediente farmaceuticamente ativo |
| JP4291962B2 (ja) * | 2001-03-27 | 2009-07-08 | あすか製薬株式会社 | 安定な甲状腺ホルモン含有固形製剤組成物 |
| WO2003057717A2 (en) | 2002-01-07 | 2003-07-17 | Abbott Gmbh & Co. Kg | Crystallization of amino acids using ultrasonic agitation |
-
2004
- 2004-05-03 BR BRPI0410021-2A patent/BRPI0410021A/pt not_active Application Discontinuation
- 2004-05-03 WO PCT/AT2004/000150 patent/WO2004096177A1/de not_active Ceased
- 2004-05-03 ES ES04730797T patent/ES2344294T3/es not_active Expired - Lifetime
- 2004-05-03 AU AU2004234176A patent/AU2004234176B2/en not_active Ceased
- 2004-05-03 DE DE502004011103T patent/DE502004011103D1/de not_active Expired - Lifetime
- 2004-05-03 AT AT04730797T patent/ATE465718T1/de active
- 2004-05-03 EP EP04730797A patent/EP1622587B1/de not_active Revoked
- 2004-05-03 DK DK04730797.0T patent/DK1622587T3/da active
- 2004-05-03 JP JP2006503952A patent/JP5414146B2/ja not_active Expired - Lifetime
- 2004-05-03 RU RU2005137577/15A patent/RU2361573C2/ru active
- 2004-05-03 CA CA2523079A patent/CA2523079C/en not_active Expired - Lifetime
- 2004-05-03 PT PT04730797T patent/PT1622587E/pt unknown
-
2005
- 2005-11-08 ZA ZA200509026A patent/ZA200509026B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU2004234176B2 (en) | 2010-05-13 |
| ES2344294T3 (es) | 2010-08-24 |
| WO2004096177A1 (de) | 2004-11-11 |
| CA2523079C (en) | 2012-08-14 |
| ZA200509026B (en) | 2007-03-28 |
| AU2004234176A1 (en) | 2004-11-11 |
| DK1622587T3 (da) | 2010-08-23 |
| CA2523079A1 (en) | 2004-11-11 |
| PT1622587E (pt) | 2010-07-07 |
| RU2361573C2 (ru) | 2009-07-20 |
| ATE465718T1 (de) | 2010-05-15 |
| JP2006525234A (ja) | 2006-11-09 |
| RU2005137577A (ru) | 2006-05-10 |
| JP5414146B2 (ja) | 2014-02-12 |
| EP1622587A1 (de) | 2006-02-08 |
| EP1622587B1 (de) | 2010-04-28 |
| DE502004011103D1 (de) | 2010-06-10 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
| B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] |
Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI |
|
| B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
| B09B | Patent application refused [chapter 9.2 patent gazette] | ||
| B09B | Patent application refused [chapter 9.2 patent gazette] |