BRPI0410820A - polipeptìdeo isolado, seqüência de ácido nucleico isolado, construção de ácido nucleico, vetor de expressão recombinante, célula hospedeira recombinante, método para a produção de um polipeptìdeo, planta transgênica, ou parte da planta, animal não humano, transgênico, ou produtos, ou elementos destes, uso de pelo menos um polipeptìdeo, aditivo para ração para animal, composição de ração para animal, e, microorganismo - Google Patents
polipeptìdeo isolado, seqüência de ácido nucleico isolado, construção de ácido nucleico, vetor de expressão recombinante, célula hospedeira recombinante, método para a produção de um polipeptìdeo, planta transgênica, ou parte da planta, animal não humano, transgênico, ou produtos, ou elementos destes, uso de pelo menos um polipeptìdeo, aditivo para ração para animal, composição de ração para animal, e, microorganismoInfo
- Publication number
- BRPI0410820A BRPI0410820A BRPI0410820-5A BRPI0410820A BRPI0410820A BR PI0410820 A BRPI0410820 A BR PI0410820A BR PI0410820 A BRPI0410820 A BR PI0410820A BR PI0410820 A BRPI0410820 A BR PI0410820A
- Authority
- BR
- Brazil
- Prior art keywords
- polypeptide
- nucleic acid
- plant
- isolated
- transgenic
- Prior art date
Links
- 230000009261 transgenic effect Effects 0.000 title abstract 4
- 241001465754 Metazoa Species 0.000 title abstract 3
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- 229920001184 polypeptide Polymers 0.000 title 3
- 102000004196 processed proteins & peptides Human genes 0.000 title 3
- 108090000765 processed proteins & peptides Proteins 0.000 title 3
- 150000007523 nucleic acids Chemical group 0.000 title 2
- 108091028043 Nucleic acid sequence Proteins 0.000 title 1
- 239000003674 animal food additive Substances 0.000 title 1
- 239000013604 expression vector Substances 0.000 title 1
- 244000005700 microbiome Species 0.000 title 1
- 108020004707 nucleic acids Proteins 0.000 title 1
- 102000039446 nucleic acids Human genes 0.000 title 1
- 238000003259 recombinant expression Methods 0.000 title 1
- 102000035195 Peptidases Human genes 0.000 abstract 5
- 108091005804 Peptidases Proteins 0.000 abstract 5
- 239000004365 Protease Substances 0.000 abstract 4
- 230000000694 effects Effects 0.000 abstract 2
- 241000203622 Nocardiopsis Species 0.000 abstract 1
- 239000003599 detergent Substances 0.000 abstract 1
- 235000019833 protease Nutrition 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/52—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/58—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from fungi
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/11—Antisense
- C12N2310/111—Antisense spanning the whole gene, or a large part of it
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Microbiology (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Mycology (AREA)
- Enzymes And Modification Thereof (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Fodder In General (AREA)
- Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
Abstract
"POLIPEPTìDEO ISOLADO, SEQüêNCIA DE áCIDO NUCLEICO ISOLADO, CONSTRUçãO DE áCIDO NUCLEICO, VETOR DE EXPRESSãO RECOMBINANTE, CéLULA HOSPEDEIRA RECOMBINANTE, MéTODO PARA A PRODUçãO DE UM POLIPEPTìDEO, PLANTA TRANSGêNICA, OU PARTE DA PLANTA, ANIMAL NãO HUMANO, TRANSGêNICO, OU PRODUTOS, OU ELEMENTOS DESTES, USO DE PELO MENOS UM POLIPEPTìDEO, ADITIVO PARA RAçãO PARA ANIMAL, COMPOSIçãO DE RAçãO PARA ANIMAL, E, MICROORGANISMO". As proteases de atividade específica alta homólogas às proteases derivadas de Nocardiopsis, e a produção destas pelo tipo selvagem, e em células hospedeiras recombinantes incluindo as plantas transgênicas e animais transgênicos não humanos. As proteases são eficazes na ração para animal, e em detergentes. Os aspectos estruturais característicos de relevância para a atividade específica destas proteases da família de peptidase S2A ou S1E são divulgados.
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DKPA200300913 | 2003-06-19 | ||
| DKPA200301492 | 2003-10-10 | ||
| DKPA200400332 | 2004-03-01 | ||
| PCT/DK2004/000433 WO2004111221A1 (en) | 2003-06-19 | 2004-06-21 | Proteases |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| BRPI0410820A true BRPI0410820A (pt) | 2006-06-27 |
| BRPI0410820B1 BRPI0410820B1 (pt) | 2016-04-26 |
Family
ID=33555916
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0410820A BRPI0410820B1 (pt) | 2003-06-19 | 2004-06-21 | uso de pelo menos um polipeptídeo isolado, método para a produção de um polipeptídeo, aditivo para ração para animal, e, composição de ração para animal. |
Country Status (12)
| Country | Link |
|---|---|
| EP (1) | EP1639106B1 (pt) |
| JP (1) | JP4880453B2 (pt) |
| CN (2) | CN1809634A (pt) |
| AT (1) | ATE469214T1 (pt) |
| AU (1) | AU2004247802B2 (pt) |
| BR (1) | BRPI0410820B1 (pt) |
| CA (1) | CA2526806C (pt) |
| DE (1) | DE602004027376D1 (pt) |
| DK (1) | DK1639106T3 (pt) |
| ES (1) | ES2346654T3 (pt) |
| PL (1) | PL1639106T3 (pt) |
| WO (1) | WO2004111221A1 (pt) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6855548B2 (en) | 2000-02-08 | 2005-02-15 | F. Hoffman-La Roche Ag | Use of acid-stable proteases in animal feed |
| DE602004007766T2 (de) | 2003-02-07 | 2008-06-05 | Novozymes A/S | Proteasen |
| WO2004111219A1 (en) * | 2003-06-19 | 2004-12-23 | Novozymes A/S | Improved proteases and methods for producing them |
| EP1639107B1 (en) | 2003-06-19 | 2013-08-14 | Novozymes A/S | Improved proteases and methods for producing them |
| ATE408682T1 (de) * | 2003-06-19 | 2008-10-15 | Novozymes As | Proteasen |
| DE602004030595D1 (de) | 2003-10-10 | 2011-01-27 | Novozymes As | Proteasevarianten |
| ES2380105T3 (es) * | 2004-06-21 | 2012-05-08 | Novozymes A/S | Proteasas de Nocardiopsis |
| JP5340138B2 (ja) * | 2006-04-30 | 2013-11-13 | フィード リサーチ インスティチュート チャイニーズ アカデミー オブ アグリカルチュアル サイエンシィズ | 新規なフィターゼのクローニング及び発現 |
| ES2584506T3 (es) | 2006-07-13 | 2016-09-28 | Dsm Ip Assets B.V. | Uso de amilasas bacterianas en pienso para animales bovinos |
| US8455235B2 (en) | 2007-12-04 | 2013-06-04 | Novozymes A/S | Protease variants for pharmaceutical use |
| EP2285944B1 (en) | 2008-05-14 | 2013-03-13 | Novozymes A/S | Liquid detergent compositions |
| JP5119202B2 (ja) * | 2009-01-29 | 2013-01-16 | 株式会社日立ハイテクノロジーズ | ヘモグロビンA1c測定装置 |
| CN102325876A (zh) * | 2009-02-19 | 2012-01-18 | 诺维信公司 | 酿造方法 |
| AU2012360992B2 (en) * | 2011-12-28 | 2018-08-09 | Novozymes A/S | Polypeptides having protease activity |
| AU2015279057B2 (en) | 2014-06-27 | 2019-02-28 | Novonesis Animal Biosolutions Ag | A method for improving the nutritional value of animal feed |
| CN106085984B (zh) * | 2016-06-02 | 2019-07-19 | 天津科技大学 | 一种新型磷脂酶d及其制备磷脂酸、磷脂酰丝氨酸的方法 |
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| GB1483591A (en) | 1973-07-23 | 1977-08-24 | Novo Industri As | Process for coating water soluble or water dispersible particles by means of the fluid bed technique |
| GB1590432A (en) | 1976-07-07 | 1981-06-03 | Novo Industri As | Process for the production of an enzyme granulate and the enzyme granuate thus produced |
| DK122686D0 (da) | 1986-03-17 | 1986-03-17 | Novo Industri As | Fremstilling af proteiner |
| DE3750450T2 (de) | 1986-08-29 | 1995-01-05 | Novo Industri As | Enzymhaltiger Reinigungsmittelzusatz. |
| NZ221627A (en) | 1986-09-09 | 1993-04-28 | Genencor Inc | Preparation of enzymes, modifications, catalytic triads to alter ratios or transesterification/hydrolysis ratios |
| JP3079276B2 (ja) | 1988-02-28 | 2000-08-21 | 天野製薬株式会社 | 組換え体dna、それを含むシュードモナス属菌及びそれを用いたリパーゼの製造法 |
| US5648263A (en) | 1988-03-24 | 1997-07-15 | Novo Nordisk A/S | Methods for reducing the harshness of a cotton-containing fabric |
| JPH02255081A (ja) | 1989-03-30 | 1990-10-15 | Snow Brand Milk Prod Co Ltd | プロテアーゼ生産菌、該菌体から産生したプロテアーゼ、及びその精製方法 |
| JPH0372876A (ja) * | 1989-08-11 | 1991-03-28 | Mitsubishi Gas Chem Co Inc | 新規アルカリ性プロテアーゼ |
| NZ237549A (en) | 1990-03-23 | 1993-06-25 | Gist Brocades Nv | Production of enhanced levels of enzymes in the seeds of transgenic plants and the use of these seeds |
| KR100236540B1 (ko) | 1990-04-14 | 2000-01-15 | 레클로우크스 라우에르 | 알카리성 바실러스-리파제, 이를 코-딩하는 dna 서열 및 리파제를 생산하는 바실러스 균주 |
| DK115890D0 (da) | 1990-05-09 | 1990-05-09 | Novo Nordisk As | Enzym |
| FI932561L (fi) | 1990-12-05 | 1993-06-04 | Novo Nordisk As | Proteiner med foeraendrade epitoper och foerfaranden foer deras framstaellning |
| ES2174820T3 (es) | 1991-01-16 | 2002-11-16 | Procter & Gamble | Composiciones detergentes compactas con celulasa de alta actividad. |
| CZ285148B6 (cs) | 1991-04-30 | 1999-05-12 | The Procter And Gamble Company | Kapalné detergentní směsi s borito-polyolovým komplexem k inhibici proteolytického enzymu |
| JPH0646850A (ja) * | 1991-12-16 | 1994-02-22 | Tosoh Corp | 新規プロテア−ゼ |
| JPH06181761A (ja) * | 1992-06-08 | 1994-07-05 | Tosoh Corp | 新規プロテアーゼ |
| DK88892D0 (da) | 1992-07-06 | 1992-07-06 | Novo Nordisk As | Forbindelse |
| WO1994002597A1 (en) | 1992-07-23 | 1994-02-03 | Novo Nordisk A/S | MUTANT α-AMYLASE, DETERGENT, DISH WASHING AGENT, AND LIQUEFACTION AGENT |
| JPH06153934A (ja) * | 1992-11-16 | 1994-06-03 | Nagase & Co Ltd | 新規な変異型酵素の製造方法 |
| KR950702240A (ko) | 1993-04-27 | 1995-06-19 | 한스 발터 라벤 | 세제로의 이용을 위한 새로운 리파제 변형체 |
| JP2859520B2 (ja) | 1993-08-30 | 1999-02-17 | ノボ ノルディスク アクティーゼルスカブ | リパーゼ及びそれを生産する微生物及びリパーゼ製造方法及びリパーゼ含有洗剤組成物 |
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| US5605793A (en) | 1994-02-17 | 1997-02-25 | Affymax Technologies N.V. | Methods for in vitro recombination |
| DE69527835T2 (de) | 1994-02-22 | 2003-04-10 | Novozymes A/S, Bagsvaerd | Methode zur herstellung einer variante eines lipolytischen enzymes |
| DE69536145D1 (de) | 1994-03-08 | 2011-04-07 | Novozymes As | Neuartige alkalische Zellulasen |
| US5689054A (en) | 1994-03-17 | 1997-11-18 | The United States Of America As Represented By The Secretary Of Agriculture | Low phytic acid mutants and selection thereof |
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| FI964808A0 (fi) | 1994-06-03 | 1996-12-02 | Novo Nordisk Biotech Inc | Puhdistetut Myceliophthora lakkaasit ja niitä koodaavat nukleiinihapot |
| AU2884695A (en) | 1994-06-23 | 1996-01-19 | Unilever Plc | Modified pseudomonas lipases and their use |
| DE4422198C2 (de) | 1994-06-24 | 1997-08-28 | Audi Ag | Verfahren zum Steuern der elektrischen Beheizung eines Katalysators |
| CN101659926A (zh) | 1994-06-30 | 2010-03-03 | 诺沃奇梅兹有限公司 | 非毒性、非产毒性、非致病性镰孢属表达系统及所用启动子和终止子 |
| DE69535733T2 (de) | 1994-10-06 | 2009-04-23 | Novozymes A/S | Ein enzympräparat mit endoglucanase aktivität |
| BE1008998A3 (fr) | 1994-10-14 | 1996-10-01 | Solvay | Lipase, microorganisme la produisant, procede de preparation de cette lipase et utilisations de celle-ci. |
| US5827719A (en) | 1994-10-26 | 1998-10-27 | Novo Nordisk A/S | Enzyme with lipolytic activity |
| WO1996016177A1 (en) | 1994-11-24 | 1996-05-30 | Novo Nordisk A/S | A process for producing polypeptides with reduced allergenicity |
| AU6655196A (en) | 1995-08-11 | 1997-03-12 | Novo Nordisk A/S | Novel lipolytic enzymes |
| US5763385A (en) | 1996-05-14 | 1998-06-09 | Genencor International, Inc. | Modified α-amylases having altered calcium binding properties |
| AU3938997A (en) | 1996-08-26 | 1998-03-19 | Novo Nordisk A/S | A novel endoglucanase |
| CA2277618A1 (en) | 1997-01-10 | 1998-07-16 | Novo Nordisk A/S | Enzyme coupled with polymeric molecules for skin care |
| JP2001511162A (ja) | 1997-02-06 | 2001-08-07 | ノボ ノルディスク アクティーゼルスカブ | 付加され、そして/又は除去された付着基を有するポリペプチド−ポリマー結合体 |
| ATE375387T1 (de) | 1997-06-25 | 2007-10-15 | Novozymes As | Modifiziertes polypeptid |
| EP1002061A1 (en) | 1997-07-04 | 2000-05-24 | Novo Nordisk A/S | FAMILY 6 ENDO-1,4-$g(b)-GLUCANASE VARIANTS AND CLEANING COMPOSIT IONS CONTAINING THEM |
| NZ330940A (en) | 1997-07-24 | 2000-02-28 | F | Production of consensus phytases from fungal origin using computer programmes |
| US5955310A (en) | 1998-02-26 | 1999-09-21 | Novo Nordisk Biotech, Inc. | Methods for producing a polypeptide in a bacillus cell |
| AU6078899A (en) | 1998-10-13 | 2000-05-01 | Novozymes A/S | A modified polypeptide with reduced immune response |
| ES2220114T3 (es) | 1998-10-30 | 2004-12-01 | Novozymes A/S | Variantes de proteinas poco alergenicas. |
| ATE365210T1 (de) | 1998-10-30 | 2007-07-15 | Novozymes As | Glykosylierte proteine mit reduzierter allergenität |
| CA2395266C (en) * | 2000-02-08 | 2009-04-14 | F. Hoffmann-La Roche Ag | Use of acid-stable subtilisin proteases in animal feed |
| JP5571274B2 (ja) | 2000-03-08 | 2014-08-13 | ノボザイムス アクティーゼルスカブ | 改変された特性を有する変異体 |
| EP1280817A2 (en) | 2000-04-28 | 2003-02-05 | Novozymes A/S | Production and use of protein variants having modified immunogenecity |
| WO2002090384A2 (en) | 2001-05-04 | 2002-11-14 | Novozymes A/S | Antimicrobial polypeptide from aspergillus niger |
| AU2002349297A1 (en) | 2001-12-03 | 2003-06-17 | Kobenhavns Amt | Statin-like compounds |
| JP4137526B2 (ja) | 2002-01-23 | 2008-08-20 | Toto株式会社 | ケラチナーゼおよびその製造法 |
| JP4114046B2 (ja) * | 2002-07-12 | 2008-07-09 | 川村通商株式会社 | 酵素脱毛処理剤および酵素脱毛法 |
| DE602004007766T2 (de) * | 2003-02-07 | 2008-06-05 | Novozymes A/S | Proteasen |
| ATE408682T1 (de) * | 2003-06-19 | 2008-10-15 | Novozymes As | Proteasen |
-
2004
- 2004-06-21 CN CNA2004800170793A patent/CN1809634A/zh active Pending
- 2004-06-21 BR BRPI0410820A patent/BRPI0410820B1/pt not_active IP Right Cessation
- 2004-06-21 WO PCT/DK2004/000433 patent/WO2004111221A1/en not_active Ceased
- 2004-06-21 CA CA2526806A patent/CA2526806C/en not_active Expired - Fee Related
- 2004-06-21 JP JP2006515726A patent/JP4880453B2/ja not_active Expired - Fee Related
- 2004-06-21 DE DE602004027376T patent/DE602004027376D1/de not_active Expired - Lifetime
- 2004-06-21 PL PL04738930T patent/PL1639106T3/pl unknown
- 2004-06-21 CN CN201110344423.1A patent/CN102505007B/zh not_active Expired - Fee Related
- 2004-06-21 DK DK04738930.9T patent/DK1639106T3/da active
- 2004-06-21 EP EP20040738930 patent/EP1639106B1/en not_active Expired - Lifetime
- 2004-06-21 AT AT04738930T patent/ATE469214T1/de not_active IP Right Cessation
- 2004-06-21 ES ES04738930T patent/ES2346654T3/es not_active Expired - Lifetime
- 2004-06-21 AU AU2004247802A patent/AU2004247802B2/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| CN102505007A (zh) | 2012-06-20 |
| JP2006527584A (ja) | 2006-12-07 |
| BRPI0410820B1 (pt) | 2016-04-26 |
| CN1809634A (zh) | 2006-07-26 |
| ATE469214T1 (de) | 2010-06-15 |
| DK1639106T3 (da) | 2010-09-27 |
| PL1639106T3 (pl) | 2010-11-30 |
| CA2526806C (en) | 2013-05-21 |
| WO2004111221A1 (en) | 2004-12-23 |
| DE602004027376D1 (de) | 2010-07-08 |
| EP1639106B1 (en) | 2010-05-26 |
| ES2346654T3 (es) | 2010-10-19 |
| JP4880453B2 (ja) | 2012-02-22 |
| CA2526806A1 (en) | 2004-12-23 |
| AU2004247802A1 (en) | 2004-12-23 |
| AU2004247802B2 (en) | 2010-08-05 |
| EP1639106A1 (en) | 2006-03-29 |
| CN102505007B (zh) | 2016-04-20 |
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