BRPI0411524A - formulação farmacêutica de amoxicilina e clavulanato, uso de carboximetilcelulose de sódio, e, método de tratar infecção bacteriana em pacientes pediátricos - Google Patents
formulação farmacêutica de amoxicilina e clavulanato, uso de carboximetilcelulose de sódio, e, método de tratar infecção bacteriana em pacientes pediátricosInfo
- Publication number
- BRPI0411524A BRPI0411524A BRPI0411524-4A BRPI0411524A BRPI0411524A BR PI0411524 A BRPI0411524 A BR PI0411524A BR PI0411524 A BRPI0411524 A BR PI0411524A BR PI0411524 A BRPI0411524 A BR PI0411524A
- Authority
- BR
- Brazil
- Prior art keywords
- clavulanate
- amoxicillin
- pharmaceutical formulation
- bacterial infection
- sodium carboxymethylcellulose
- Prior art date
Links
- HZZVJAQRINQKSD-UHFFFAOYSA-N Clavulanic acid Natural products OC(=O)C1C(=CCO)OC2CC(=O)N21 HZZVJAQRINQKSD-UHFFFAOYSA-N 0.000 title abstract 3
- LSQZJLSUYDQPKJ-NJBDSQKTSA-N amoxicillin Chemical compound C1([C@@H](N)C(=O)N[C@H]2[C@H]3SC([C@@H](N3C2=O)C(O)=O)(C)C)=CC=C(O)C=C1 LSQZJLSUYDQPKJ-NJBDSQKTSA-N 0.000 title abstract 3
- 229960003022 amoxicillin Drugs 0.000 title abstract 3
- 229940090805 clavulanate Drugs 0.000 title abstract 3
- HZZVJAQRINQKSD-PBFISZAISA-N clavulanic acid Chemical compound OC(=O)[C@H]1C(=C/CO)/O[C@@H]2CC(=O)N21 HZZVJAQRINQKSD-PBFISZAISA-N 0.000 title abstract 3
- LSQZJLSUYDQPKJ-UHFFFAOYSA-N p-Hydroxyampicillin Natural products O=C1N2C(C(O)=O)C(C)(C)SC2C1NC(=O)C(N)C1=CC=C(O)C=C1 LSQZJLSUYDQPKJ-UHFFFAOYSA-N 0.000 title abstract 3
- 208000035143 Bacterial infection Diseases 0.000 title abstract 2
- DPXJVFZANSGRMM-UHFFFAOYSA-N acetic acid;2,3,4,5,6-pentahydroxyhexanal;sodium Chemical compound [Na].CC(O)=O.OCC(O)C(O)C(O)C(O)C=O DPXJVFZANSGRMM-UHFFFAOYSA-N 0.000 title abstract 2
- 208000022362 bacterial infectious disease Diseases 0.000 title abstract 2
- 239000001768 carboxy methyl cellulose Substances 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 235000019812 sodium carboxymethyl cellulose Nutrition 0.000 title abstract 2
- 229920001027 sodium carboxymethylcellulose Polymers 0.000 title abstract 2
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 abstract 1
- 239000007900 aqueous suspension Substances 0.000 abstract 1
- 238000009472 formulation Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 229910052708 sodium Inorganic materials 0.000 abstract 1
- 239000011734 sodium Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
- A61K31/424—Oxazoles condensed with heterocyclic ring systems, e.g. clavulanic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/429—Thiazoles condensed with heterocyclic ring systems
- A61K31/43—Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
"FORMULAçãO FARMACêUTICA DE AMOXICILINA E CLAVULANATO, USO DE CARBOXIMETILCELULOSE DE SóDIO, E, MéTODO DE TRATAR INFECçãO BACTERIANA EM PACIENTES PEDIáTRICOS". Formulações compreendem amoxicilina e clavulanato para reconstituição em uma suspensão aquosa incorporando baixos níveis de sódio carboximetilcelulose para estabilizar o pH da mesma.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US47876903P | 2003-06-16 | 2003-06-16 | |
| GBGB0313913.6A GB0313913D0 (en) | 2003-06-16 | 2003-06-16 | New use |
| PCT/EP2004/006551 WO2004110441A1 (en) | 2003-06-16 | 2004-06-15 | Pharmaceutical formulations comprising amoxicillin and clavulanate |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0411524A true BRPI0411524A (pt) | 2006-08-01 |
Family
ID=33420899
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0411524-4A BRPI0411524A (pt) | 2003-06-16 | 2004-06-15 | formulação farmacêutica de amoxicilina e clavulanato, uso de carboximetilcelulose de sódio, e, método de tratar infecção bacteriana em pacientes pediátricos |
Country Status (13)
| Country | Link |
|---|---|
| EP (1) | EP1491195A1 (pt) |
| JP (1) | JP2006527726A (pt) |
| KR (1) | KR20060010838A (pt) |
| AU (1) | AU2004246811A1 (pt) |
| BR (1) | BRPI0411524A (pt) |
| CA (1) | CA2529102A1 (pt) |
| CO (1) | CO5640085A2 (pt) |
| IL (1) | IL172096A0 (pt) |
| MA (1) | MA27850A1 (pt) |
| MX (1) | MXPA05013433A (pt) |
| NO (1) | NO20055882L (pt) |
| RU (1) | RU2343931C2 (pt) |
| WO (1) | WO2004110441A1 (pt) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102007002924A1 (de) * | 2007-01-19 | 2008-07-24 | Bayer Healthcare Ag | ß-Lactam-haltige Formulierungen mit erhöhter Stabilität in wässriger Lösung |
| KR20140117523A (ko) * | 2012-01-10 | 2014-10-07 | 마이클 스펙터 | 아목시실린 및 클라불란산 칼륨의 소아용 경구 현탁 제형 및 이를 사용하기 위한 방법 |
| CN114668724B (zh) * | 2020-12-24 | 2023-08-22 | 鲁南制药集团股份有限公司 | 一种阿莫西林克拉维酸钾干混悬剂及其制备方法 |
| CN114886893B (zh) * | 2021-07-30 | 2023-09-29 | 江苏恒丰强生物技术有限公司 | 一种复方阿莫西林粉及其制备方法 |
| CN116327760A (zh) * | 2022-12-26 | 2023-06-27 | 南京臣功制药股份有限公司 | 一种阿莫西林克拉维酸钾缓释干混悬剂及其制备方法 |
| WO2025141532A1 (en) * | 2023-12-29 | 2025-07-03 | Aodh Lifesciences Private Limited | Amoxicillin clavulanate nasal spray |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2280857A1 (en) * | 1997-02-14 | 1998-08-20 | Smithkline Beecham Laboratoires Pharmaceutiques | Pharmaceutical formulations comprising amoxocyllin and clavulanate |
| GB9815532D0 (en) * | 1998-07-17 | 1998-09-16 | Lek Pharmaceutical & Cvhemical | Pharmaceutical suspension formulation |
| US6177421B1 (en) * | 1999-05-04 | 2001-01-23 | Fuisz International Ltd. | Amoxicillin and clavulanate composition |
| WO2001013883A1 (en) * | 1999-08-20 | 2001-03-01 | Smithkline Beecham Laboratoires Pharmaceutiques S.A.S. | Pharmaceutical formulation comprising amoxycillin and clavulanate |
-
2004
- 2004-06-15 CA CA002529102A patent/CA2529102A1/en not_active Abandoned
- 2004-06-15 WO PCT/EP2004/006551 patent/WO2004110441A1/en not_active Ceased
- 2004-06-15 AU AU2004246811A patent/AU2004246811A1/en not_active Abandoned
- 2004-06-15 JP JP2006515979A patent/JP2006527726A/ja active Pending
- 2004-06-15 RU RU2005138127/15A patent/RU2343931C2/ru not_active IP Right Cessation
- 2004-06-15 BR BRPI0411524-4A patent/BRPI0411524A/pt not_active IP Right Cessation
- 2004-06-15 MX MXPA05013433A patent/MXPA05013433A/es not_active Application Discontinuation
- 2004-06-15 EP EP20040076764 patent/EP1491195A1/en not_active Ceased
- 2004-06-15 KR KR1020057024090A patent/KR20060010838A/ko not_active Withdrawn
-
2005
- 2005-11-22 IL IL172096A patent/IL172096A0/en unknown
- 2005-12-09 MA MA28647A patent/MA27850A1/fr unknown
- 2005-12-12 NO NO20055882A patent/NO20055882L/no not_active Application Discontinuation
- 2005-12-12 CO CO05125090A patent/CO5640085A2/es not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| KR20060010838A (ko) | 2006-02-02 |
| RU2005138127A (ru) | 2006-07-27 |
| MXPA05013433A (es) | 2006-03-09 |
| IL172096A0 (en) | 2009-02-11 |
| WO2004110441A1 (en) | 2004-12-23 |
| AU2004246811A1 (en) | 2004-12-23 |
| JP2006527726A (ja) | 2006-12-07 |
| CA2529102A1 (en) | 2004-12-23 |
| RU2343931C2 (ru) | 2009-01-20 |
| WO2004110441A8 (en) | 2005-03-17 |
| MA27850A1 (fr) | 2006-04-03 |
| EP1491195A1 (en) | 2004-12-29 |
| NO20055882L (no) | 2005-12-28 |
| CO5640085A2 (es) | 2006-05-31 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DOP2000000114A (es) | Oxazolidinonas substituidas y su uso | |
| CU23367A3 (es) | Formulación de moxifloxacino con sal común | |
| BRPI0412526A (pt) | composto, uso de um composto, composição farmacêutica, formulação em aerossol farmacêutica, e, método para o tratamento de um paciente humano ou animal com uma condição anti-inflamatória e/ou alérgica | |
| BR0109779A (pt) | Soluções moleculares hidrofìlicas dispersas de carvedilol | |
| WO2001092288A3 (en) | Cobalamin compounds useful as antibiotic agents and as imaging agents | |
| BR0212898A (pt) | Método de tratamento de infecções do ouvido médio | |
| BR0214757A (pt) | Formulações farmacêuticas de derivados de platina | |
| BR0317104A (pt) | Composições farmacêuticas dispersáveis | |
| BRPI0008228B8 (pt) | composição farmacêutica contendo n-benzoil estaurosporina e agentes solubilizantes | |
| DK0806941T3 (da) | Liposomalt antibakterielt præparat med lav fasthed | |
| HN1999000183A (es) | Preparado farmaceuticos de moxifloxacina | |
| AU2001296865A1 (en) | (5-(2-hydroxy-4-chlorobenzoyl) aminovaleric acid and salts thereof and compositions containing the same for delivering active agents | |
| BRPI0408256A (pt) | composto, métodos de tratamento de um humano ou animal, pela limitação da replicação de células, que sofre de cáncer, que sofre de uma doença neoplástica, e que se sofre de doenças proliferativas, uso de um composto, e, processo para a preparação de um composto ou de um seu sal farmaceuticamente aceitável ou de um éster hidrolisável in vivo do mesmo | |
| DE50005529D1 (de) | Orale darreichungsformen zur verabreichung einer fixen kombination von tramadol und diclofenac | |
| MY140630A (en) | Benzimidazole derivatives, compositions containing them, preparation thereof and uses thereof | |
| TW200504029A (en) | Benzimidazole derivatives, compositions containing them, preparation thereof and uses thereof | |
| BR0213994A (pt) | Derivados heterocìclicos de glicinamida e seus usos médicos | |
| MXPA05013050A (es) | Derivados de bencimidazol, composiciones que los contienen preparacion de los mismos y usos de los mismos. | |
| BRPI0411524A (pt) | formulação farmacêutica de amoxicilina e clavulanato, uso de carboximetilcelulose de sódio, e, método de tratar infecção bacteriana em pacientes pediátricos | |
| DE602005008122D1 (de) | Synergistische antibakterielle Formulierung und Herstellungsmethode | |
| SE0302570D0 (sv) | Benzimidazole derivatives, compositions containing them, preparation thereof and uses thereof | |
| BRPI0412453A (pt) | uso do ácido ascórbico ou um sal fisiologicamente aceitável do mesmo | |
| SE0302572D0 (sv) | Benzimidazole derivatives, compositions containing them, preparation thereof and uses thereof | |
| UY27373A1 (es) | Formulaciones de interferón beta-humano | |
| TW200505429A (en) | Pharmaceutical composition |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE AS 7A E 8A ANUIDADES. |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2159 DE 22/05/2012. |