BRPI0411534A - derivados de lincomicina com atividade antimicrobiana - Google Patents

derivados de lincomicina com atividade antimicrobiana

Info

Publication number: BRPI0411534A
Authority: BR; Brazil
Prior art keywords: derivatives; lincomycin derivatives; antimicrobial activity; lincomycin; compounds
Prior art date: 2003-06-17

Application number

BRPI0411534-1A

Other languages

English (en)

Portuguese (pt)

Inventor

Jason G Lewis

Sampath K Anandan

Hardwin O'dowd

Mikhail F Gordeev

Original Assignee

Vicuron Pharm Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2003-06-17

Filing date

2004-06-17

Publication date

2006-08-22

2003-08-15 Priority claimed from US10/642,807 external-priority patent/US7164011B2/en

2004-02-11 Priority claimed from US10/777,455 external-priority patent/US7199105B2/en

2004-06-17 Application filed by Vicuron Pharm Inc filed Critical Vicuron Pharm Inc

2006-08-22 Publication of BRPI0411534A publication Critical patent/BRPI0411534A/pt

Links

OJMMVQQUTAEWLP-KIDUDLJLSA-N lincomycin Chemical class CN1C[C@H](CCC)C[C@H]1C(=O)N[C@H]([C@@H](C)O)[C@@H]1[C@H](O)[C@H](O)[C@@H](O)[C@@H](SC)O1 OJMMVQQUTAEWLP-KIDUDLJLSA-N 0.000 title abstract 3
230000000845 anti-microbial effect Effects 0.000 title 1
150000001875 compounds Chemical class 0.000 abstract 2
230000000694 effects Effects 0.000 abstract 2
241000894006 Bacteria Species 0.000 abstract 1
230000000844 anti-bacterial effect Effects 0.000 abstract 1
230000003515 anti-microbian Effects 0.000 abstract 1
239000004599 antimicrobial Substances 0.000 abstract 1
230000015572 biosynthetic process Effects 0.000 abstract 1
238000000034 method Methods 0.000 abstract 1
230000003389 potentiating effect Effects 0.000 abstract 1
238000003786 synthesis reaction Methods 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/02—Acyclic radicals, not substituted by cyclic structures
- C07H15/14—Acyclic radicals, not substituted by cyclic structures attached to a sulfur, selenium or tellurium atom of a saccharide radical
- C07H15/16—Lincomycin; Derivatives thereof

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Molecular Biology (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Engineering & Computer Science (AREA)
Biochemistry (AREA)
Epidemiology (AREA)
Genetics & Genomics (AREA)
Biotechnology (AREA)
Crystallography & Structural Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Saccharide Compounds (AREA)

BRPI0411534-1A 2003-06-17 2004-06-17 derivados de lincomicina com atividade antimicrobiana BRPI0411534A (pt)

Applications Claiming Priority (5)

Application Number	Priority Date	Filing Date	Title
US47950203P	2003-06-17	2003-06-17
US47929603P	2003-06-17	2003-06-17
US10/642,807 US7164011B2 (en)	2002-08-15	2003-08-15	Lincomycin derivatives possessing antibacterial activity
US10/777,455 US7199105B2 (en)	2002-08-15	2004-02-11	Lincomycin derivatives possessing antibacterial activity
PCT/US2004/019689 WO2005012320A2 (en)	2003-06-17	2004-06-17	Novel lincomycin derivatives possessing antimicrobial activity

Publications (1)

Publication Number	Publication Date
BRPI0411534A true BRPI0411534A (pt)	2006-08-22

Family

ID=40203032

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BRPI0411534-1A BRPI0411534A (pt)	2003-06-17	2004-06-17	derivados de lincomicina com atividade antimicrobiana

Country Status (16)

Country	Link
EP (1)	EP1644393A2 (no)
JP (1)	JP2007516172A (no)
KR (1)	KR20060091050A (no)
AU (1)	AU2004261550A1 (no)
BR (1)	BRPI0411534A (no)
CA (1)	CA2528592A1 (no)
EC (1)	ECSP056233A (no)
GE (1)	GEP20084437B (no)
IL (1)	IL172183A0 (no)
IS (1)	IS8147A (no)
MA (1)	MA27860A1 (no)
MX (1)	MXPA05013915A (no)
NO (1)	NO20055893L (no)
OA (1)	OA13179A (no)
RS (1)	RS20050931A (no)
WO (1)	WO2005012320A2 (no)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US7199105B2 (en)	2002-08-15	2007-04-03	Vicuron Pharmaceuticals, Inc.	Lincomycin derivatives possessing antibacterial activity
KR20050056195A (ko)	2002-08-15	2005-06-14	비큐론 파마슈티컬스 인코포레이티드	항박테리아 작용을 갖는 링코마이신 유도체
US7256177B2 (en)	2003-06-17	2007-08-14	Vicuron Pharmaceuticals, Inc.	Lincomycin derivatives possessing antibacterial activity
CA2528596A1 (en) *	2003-06-17	2005-01-27	Vicuron Pharmaceuticals Inc.	Lincomycin derivatives possessing antibacterial activity
US7199106B2 (en)	2003-06-17	2007-04-03	Vicuron Pharmaceuticals, Inc.	Lincomycin derivatives possessing antimicrobial activity
US7361743B2 (en) *	2004-02-11	2008-04-22	Pfizer Inc	Lincomycin derivatives possessing antibacterial activity
BRPI0615300A2 (pt) *	2005-08-31	2009-07-14	Wyeth Corp	composto; composição farmacêutica; método para a preparação, tratamento ou controle de infecções bacterianas em animais de sangue quente; uso de um composto; e método para a preparação de compostos representados pela fórmula (i)
EP1970377A4 (en)	2005-12-09	2013-02-27	Meiji Seika Kaisha	LINCOMYCIN DERIVATIVE AND ANTIBACTERIAL AGENT CONTAINING THIS AS AN ACTIVE SUBSTANCE
WO2008146919A1 (ja)	2007-05-31	2008-12-04	Meiji Seika Kaisha, Ltd.	リンコサミド誘導体及びこれを有効成分とする抗菌剤
EP2151447A4 (en) *	2007-05-31	2012-09-05	Meiji Seika Kaisha	LINCOMYCIN DERIVATIVES AND ANTIBACTERIAL AGENTS CONTAINING SAME AS ACTIVE INGREDIENTS
US20130267699A1 (en)	2011-06-24	2013-10-10	California Institute Of Technology	Quaternary heteroatom containing compounds
US8822679B2 (en) *	2011-06-24	2014-09-02	California Institute Of Technology	Quaternary heteroatom containing compounds
US10421696B2 (en)	2014-12-18	2019-09-24	California Institute Of Technology	Enantioselective synthesis of α-quaternary mannich adducts by palladium-catalyzed allylic alkylation
US10106479B2 (en)	2015-03-27	2018-10-23	California Institute Of Technology	Asymmetric catalytic decarboxylative alkyl alkylation using low catalyst concentrations and a robust precatalyst
EP3426391A4 (en)	2016-03-11	2019-08-28	California Institute of Technology	COMPOSITIONS AND METHODS FOR ACYLATING LACTAMEN
EP3480190B1 (en)	2017-11-01	2023-01-04	California Institute of Technology	Methods for enantioselective allylic alkylation of esters, lactones, and lactams with unactivated allylic alcohols
EP3699173A1 (en)	2018-10-18	2020-08-26	California Institute of Technology	Gem-disubstituted pyrrolidines, piperazines, and diazepanes, and compositions and methods of making the same
CN110357839A (zh) *	2019-08-29	2019-10-22	重庆经致制药技术开发有限公司	布瓦西坦手性中间体的制备方法

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3268556A (en) *	1964-04-13	1966-08-23	Upjohn Co	Novel lincomycin derivatives
NL128232C (no) *	1964-04-13
NL146501C (no) *	1964-07-01
US3282917A (en) *	1964-08-17	1966-11-01	Upjohn Co	Methyl n-(1-alkyl-4-alkoxy-prolyl)-alpha-thiolincosaminide compounds and process therefor
NL140527B (nl) *	1965-02-08	1973-12-17	Upjohn Co	Werkwijze ter bereiding van aan lincomycine verwante verbindingen.
US3496163A (en) *	1965-02-08	1970-02-17	Upjohn Co	7-halo-7-deoxylincomycins and process for preparing the same
US3555007A (en) *	1968-07-22	1971-01-12	Upjohn Co	7-deoxy-7-halo lincomycin d derivatives
US3549615A (en) *	1968-10-17	1970-12-22	Upjohn Co	Lincomycin derivatives and process for producing the same
DE2118636A1 (de) *	1970-04-20	1971-11-04	The Upjohn Co., Kalamazoo, Mich. (V.StA.)	3-Nucleotide von Lincomycin und deren Analogen, Verfahren zu ihrer Herstellung und ihre Verwendung in therapeutischen Präparaten
US3787390A (en) *	1971-06-23	1974-01-22	Upjohn Co	Analogs of lincomycin and process
US3849396A (en) *	1973-01-08	1974-11-19	Upjohn Co	Lincomycin and clindamycin 1-o-ethers
US3923602A (en) *	1973-10-25	1975-12-02	Upjohn Co	Composition of matter and process
JPS5641239A (en) *	1979-09-13	1981-04-17	Hitachi Cable Ltd	Flame-retardant composition
US4278789A (en) *	1979-11-23	1981-07-14	The Upjohn Company	Lincomycin compounds
KR20050056195A (ko) *	2002-08-15	2005-06-14	비큐론 파마슈티컬스 인코포레이티드	항박테리아 작용을 갖는 링코마이신 유도체
BRPI0411537A (pt) *	2003-06-17	2006-08-01	Vicuron Pharm Inc	derivados de lincomicina que possuem atividade antibacteriana

2004
- 2004-06-17 OA OA1200500364A patent/OA13179A/en unknown
- 2004-06-17 CA CA002528592A patent/CA2528592A1/en not_active Abandoned
- 2004-06-17 RS YUP-2005/0931A patent/RS20050931A/sr unknown
- 2004-06-17 GE GEAP20049117A patent/GEP20084437B/en unknown
- 2004-06-17 AU AU2004261550A patent/AU2004261550A1/en not_active Abandoned
- 2004-06-17 BR BRPI0411534-1A patent/BRPI0411534A/pt not_active IP Right Cessation
- 2004-06-17 EP EP04776816A patent/EP1644393A2/en not_active Withdrawn
- 2004-06-17 JP JP2006517464A patent/JP2007516172A/ja active Pending
- 2004-06-17 MX MXPA05013915A patent/MXPA05013915A/es unknown
- 2004-06-17 WO PCT/US2004/019689 patent/WO2005012320A2/en not_active Ceased
- 2004-06-17 KR KR1020057024291A patent/KR20060091050A/ko not_active Ceased
2005
- 2005-11-24 IL IL172183A patent/IL172183A0/en unknown
- 2005-11-24 IS IS8147A patent/IS8147A/is unknown
- 2005-12-12 NO NO20055893A patent/NO20055893L/no not_active Application Discontinuation
- 2005-12-16 MA MA28672A patent/MA27860A1/fr unknown
- 2005-12-16 EC EC2005006233A patent/ECSP056233A/es unknown

Also Published As

Publication number	Publication date
CA2528592A1 (en)	2005-02-10
HK1090061A1 (zh)	2006-12-15
JP2007516172A (ja)	2007-06-21
EP1644393A2 (en)	2006-04-12
NO20055893L (no)	2006-03-14
RS20050931A (sr)	2008-04-04
WO2005012320A3 (en)	2005-10-20
MA27860A1 (fr)	2006-04-03
OA13179A (en)	2006-12-13
WO2005012320A2 (en)	2005-02-10
KR20060091050A (ko)	2006-08-17
AU2004261550A1 (en)	2005-02-10
ECSP056233A (es)	2006-04-19
GEP20084437B (en)	2008-07-25
MXPA05013915A (es)	2006-07-03
IS8147A (is)	2005-11-24
IL172183A0 (en)	2011-08-01

Legal Events

Date	Code	Title	Description
2011-10-25	B08F	Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]	Free format text: REFERENTE A 6A E 7A ANUIDADES.
2012-05-15	B08K	Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]	Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2129 DE 25/10/2011.

Publication	Publication Date	Title
BRPI0411534A (pt)	2006-08-22	derivados de lincomicina com atividade antimicrobiana
EA200600280A1 (ru)	2006-10-27	Композиции на основе производных липопептидных антибиотиков и способы их применения
CY1106958T1 (el)	2012-09-26	Ν-αλκυλο-4-μεθυλεναμινο-3-υδροξυ-2-πυριδονες ως αντιμικροβιακα
ATE482616T1 (de)	2010-10-15	Zusammensetzungen mit hoher antiviraler und antibakterieller wirkung
DE60207686D1 (de)	2006-01-05	Kombinationen von antiseptischen und antibiotischen mitteln enthaltende medizinische vorrichtungen
NO996269L (no)	2000-02-16	Kinolin-indol antimikrobielle midler, samt anvendelse og blandinger derav
BR0012674A (pt)	2002-09-17	Formulações farmacêuticas preservadas
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EP3738591A3 (en)	2021-03-24	Novel antibacterial agents
WO2005019241A3 (en)	2005-12-22	Cationic antimicrobial peptides and compositions thereof
TR200200883T2 (tr)	2002-09-23	2-ikameli 1,1-bifenil-2-karbonamidler, imalat yöntemleri, ilaç olarak kullanılmaları
PT1077718E (pt)	2002-12-31	Melhoramentos da actividade de agentes antibacterianos de oxazolidinona por derivados de arginina
PT1056454E (pt)	2003-08-29	Utilizacao de compostos macrolido para o tratamento do glaucoma
ATE335499T1 (de)	2006-09-15	Zusammensetzungen zur behandlung von staphylococcus aureus infektionen
BG108498A (en)	2005-03-31	New derivatives of oxazolidinones as antibacterial agents
BR0313725A (pt)	2006-06-13	derivados de lincomicina que possuem atividade antibacteriana
WO2007001335A3 (en)	2007-10-18	Ramoplanin derivatives possessing antibacterial activity
WO2006055070A3 (en)	2006-07-20	Novel lincomycin derivatives possessing antibacterial activity
ES2178761T3 (es)	2003-01-01	Utilizacion de 1-hidroxi-2-piridonas para el tratamiento de infe cciones cutaneas.
ATE372986T1 (de)	2007-09-15	N-sulfonyl-4-methyleneamino-3-hydroxy-2-pyridon s als antimikrobielle mittel
ECSP044971A (es)	2004-03-23	Isoxazolopiridinonas y su uso en el tratamiento de enfermedad de parkinson
ATE165101T1 (de)	1998-05-15	Basische prolinamid derivate von ge2270 und ge2270-ahnlichten antibiotika
BR0309878A (pt)	2005-04-19	Heterotriciclil-6-alquilideno-penemas como inibidores de beta-lactamase
AR025379A1 (es)	2002-11-20	9a-azalidas con actividad antibacteriana.
ATE417052T1 (de)	2008-12-15	Oxazaborolidine als bakterielle effektoren