BRPI0412030A - método de ensaio, método para identificar um sensor que especificamente se liga em um alvo centrossÈmico, e, solução alcoólica conservante - Google Patents
método de ensaio, método para identificar um sensor que especificamente se liga em um alvo centrossÈmico, e, solução alcoólica conservanteInfo
- Publication number
- BRPI0412030A BRPI0412030A BRPI0412030-2A BRPI0412030A BRPI0412030A BR PI0412030 A BRPI0412030 A BR PI0412030A BR PI0412030 A BRPI0412030 A BR PI0412030A BR PI0412030 A BRPI0412030 A BR PI0412030A
- Authority
- BR
- Brazil
- Prior art keywords
- target
- sensor
- identifying
- preservative
- alcohol solution
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 9
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 title abstract 6
- 239000003755 preservative agent Substances 0.000 title abstract 5
- 230000002335 preservative effect Effects 0.000 title abstract 5
- 238000010998 test method Methods 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 abstract 1
- 239000013076 target substance Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6881—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for tissue or cell typing, e.g. human leukocyte antigen [HLA] probes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6841—In situ hybridisation
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
- C12Q1/701—Specific hybridization probes
- C12Q1/708—Specific hybridization probes for papilloma
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Engineering & Computer Science (AREA)
- Analytical Chemistry (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Virology (AREA)
- Cell Biology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
Abstract
"MéTODO DE ENSAIO, MéTODO PARA IDENTIFICAR UM SENSOR QUE ESPECIFICAMENTE SE LIGA EM UM ALVO CENTROSSÈMICO, E, SOLUçãO ALCOóLICA CONSERVANTE". Esta invenção refere-se aos métodos, artigos e às composições úteis na detecção de substâncias alvo em uma solução alcoólica conservante, e para identificar sensores úteis para ligar tais alvos. Os métodos permitem as simultâneas realização de fixação suficiente de uma amostra e ligação de um sensor detectável em um alvo de interesse na amostra. Em um aspecto, um método é proporcionado o qual compreende contatar uma amostra suspeita de conter um alvo com uma molécula sensora detectável conhecida em se ligar em tal alvo em uma solução alcoólica conservante. O método pode ser realizado na forma multiplex para permitir análise simultânea de uma pluralidade de alvos. Métodos para identificar um sensor capaz de se ligar em um alvo desejado em uma solução alcoólica conservante também são proporcionados. Uma solução alcoólica conservante compreendendo um ou mais tais sensores detectáveis também é proporcionada. Também é proporcionada uma amostra compreendendo um sensor ligado proporcionado por um tal processo. Também são proporcionados kits úteis para tais métodos.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/618,443 US20040115692A1 (en) | 2000-04-03 | 2003-07-11 | Methods, compositions and apparatuses for detecting a target in a preservative solution |
| PCT/US2004/022390 WO2005007872A2 (en) | 2003-07-11 | 2004-07-09 | Detection of a target in a preservative solution |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0412030A true BRPI0412030A (pt) | 2006-09-05 |
Family
ID=34079713
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0412030-2A BRPI0412030A (pt) | 2003-07-11 | 2004-07-09 | método de ensaio, método para identificar um sensor que especificamente se liga em um alvo centrossÈmico, e, solução alcoólica conservante |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US20040115692A1 (pt) |
| EP (1) | EP1644525A4 (pt) |
| JP (1) | JP2007524843A (pt) |
| KR (1) | KR20060029633A (pt) |
| CN (2) | CN101329275A (pt) |
| AU (1) | AU2004258176B2 (pt) |
| BR (1) | BRPI0412030A (pt) |
| CA (1) | CA2531002A1 (pt) |
| IL (1) | IL172741A0 (pt) |
| WO (1) | WO2005007872A2 (pt) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8068988B2 (en) | 2003-09-08 | 2011-11-29 | Ventana Medical Systems, Inc. | Method for automated processing of digital images of tissue micro-arrays (TMA) |
| WO2005027015A2 (en) | 2003-09-10 | 2005-03-24 | Bioimagene, Inc. | Method and system for quantitatively analyzing biological samples |
| DE602005022714D1 (de) * | 2004-06-03 | 2010-09-16 | Advandx Inc | Hybridisierung von pna-sonden in alkohollösungen |
| US20060189893A1 (en) * | 2005-01-06 | 2006-08-24 | Diamics, Inc. | Systems and methods for detecting abnormal cells |
| US20060161076A1 (en) * | 2005-01-06 | 2006-07-20 | Diamics, Inc. | Systems and methods for collection of cell clusters |
| NL2005244A (en) * | 2009-09-22 | 2011-03-23 | Asml Netherlands Bv | Support or table for lithographic apparatus, method of manufacturing such support or table and lithographic apparatus comprising such support or table. |
| US20130203055A1 (en) * | 2010-06-03 | 2013-08-08 | Joan Aurich-Costa | Methods and kits for in situ detection of nucleotide sequences |
| CN102260731B (zh) * | 2011-06-28 | 2015-03-25 | 合肥安旸生物医药有限公司 | 用于膀胱癌筛查的酶标液基细胞学染色试剂盒 |
| AP2014007466A0 (en) * | 2011-08-04 | 2014-02-28 | Univ California | Salvia collection, processing, stabilization, and storage method |
| CN104145027A (zh) | 2011-12-12 | 2014-11-12 | 塞雷公司 | 用于室温原位检测生物样品中的目标核酸的方法和试剂盒 |
| CN102919218B (zh) * | 2012-11-21 | 2014-03-05 | 湖北维达健基因技术有限公司 | 一种人体唾液保存用组合物及其制备方法 |
| JP2014209090A (ja) * | 2013-03-29 | 2014-11-06 | シスメックス株式会社 | 細胞分析方法及び装置 |
| CN104849122A (zh) * | 2015-06-02 | 2015-08-19 | 蒋春亮 | 一种长效肿瘤组织渗液样本保存液 |
| AU2016287037B2 (en) | 2015-06-30 | 2017-09-07 | Sysmex Corporation | Cell preservative solution, use of same, and method for producing cell preservative solution |
| CN105274185A (zh) * | 2015-11-16 | 2016-01-27 | 南京邦博生物技术有限公司 | 一种用于结核杆菌检测的痰液处理液 |
| EP3452805A4 (en) * | 2016-05-03 | 2020-04-01 | Rarecyte, Inc. | SOLUTIONS FOR PROCESSING SAMPLES |
| CN110325652A (zh) * | 2016-06-29 | 2019-10-11 | 易捷仪器诊断股份有限公司 | 使用流动池检测分子的装置和方法 |
| GB201716883D0 (en) | 2017-10-13 | 2017-11-29 | Q-Linea Ab | Method for determining the concentration of intact microorganisms in a sample |
| GB201801022D0 (en) * | 2018-01-22 | 2018-03-07 | Q Linea Ab | Single dye concentration determination |
| EP3976816A4 (en) * | 2019-05-28 | 2023-10-25 | Case Western Reserve University | COMPOSITIONS AND METHODS FOR PRESERVING DNA METHYLATION |
| AU2021281223A1 (en) | 2020-05-27 | 2023-01-05 | Case Western Reserve University | Compositions and methods for preserving DNA methylation |
| CN112014367A (zh) * | 2020-08-14 | 2020-12-01 | 四川大学华西第二医院 | AuNPs1-2 pH探针在男性不育症中的应用和产品 |
| CN118071370B (zh) * | 2024-02-07 | 2024-08-30 | 长江勘测规划设计研究有限责任公司 | 排水管网排口出流水体中溶解性有机物的溯源方法及系统 |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE454781B (sv) * | 1986-10-17 | 1988-05-30 | Wallac Oy | Hybridiseringsforfarande for detektion av polynukleotidsekvens |
| JPH04502552A (ja) * | 1988-08-31 | 1992-05-14 | アプロジェネックス,インク | ワン―ステップのインシチュハイブリッド形成分析法 |
| US5225326A (en) * | 1988-08-31 | 1993-07-06 | Research Development Foundation | One step in situ hybridization assay |
| US5256571A (en) * | 1991-05-01 | 1993-10-26 | Cytyc Corporation | Cell preservative solution |
| ES2145750T3 (es) * | 1991-11-14 | 2000-07-16 | Dgi Inc | Kit y dosificado que utiliza la hibridacion no radioactiva. |
| US6007994A (en) * | 1995-12-22 | 1999-12-28 | Yale University | Multiparametric fluorescence in situ hybridization |
| US5972626A (en) * | 1997-07-30 | 1999-10-26 | University Of Massachusetts | Cancer detection by centrosome abnormality |
| PT1038022E (pt) * | 1997-12-12 | 2005-11-30 | Digene Corp | Avaliacao de doencas relacionadas com o virus papiloma humano |
| ES2344873T3 (es) * | 1998-05-18 | 2010-09-08 | Igenex, Inc. | Procedimiento de hibridacion in situ para detectar un acido nucleico diana. |
| US6204375B1 (en) * | 1998-07-31 | 2001-03-20 | Ambion, Inc. | Methods and reagents for preserving RNA in cell and tissue samples |
| US6280946B2 (en) * | 1998-08-07 | 2001-08-28 | Boston Probes, Inc. | PNA probes, probe sets, methods and kits pertaining to the universal detection of bacteria and eucarya |
| DK1058739T3 (da) * | 1998-11-05 | 2006-10-09 | Ortho Mcneil Pharm Inc | Fremgangsmåde til dannelse af genekspressionsprofiler |
| WO2002037944A2 (en) * | 2000-10-18 | 2002-05-16 | Virtual Arrays, Inc. | Multiplexed cell analysis system |
| ATE335847T1 (de) * | 1999-05-03 | 2006-09-15 | Gen Probe Inc | Poynukleotidsonden zur exklusiven detektion und quantifizierung von staphylococcus |
| US6337189B1 (en) * | 2000-02-08 | 2002-01-08 | Streck Laboratories, Inc. | Fixative system, method and composition for biological testing |
| ATE456668T1 (de) * | 2000-04-03 | 2010-02-15 | Cytyc Corp | Nachweis und typisierung des papillomavirus mittels pna-sonden |
| US6936443B2 (en) * | 2000-04-03 | 2005-08-30 | Cytyc Corporation | Detection and typing of human papillomavirus using PNA probes |
| US6790636B1 (en) * | 2000-06-14 | 2004-09-14 | The United States Of America As Represented By The Department Of Health And Human Services | Rapid fluorescent labeling of tissue for microdissection using fluorescent specific binding agents |
| BR0112385A (pt) * | 2000-06-21 | 2003-06-17 | Digene Corp | Meio de coleta universal |
| FI20002623A7 (fi) * | 2000-11-30 | 2002-05-31 | Inno Trac Diagnostics Oy | Bioanalyyttinen määritysmenetelmä |
| JP2002236125A (ja) * | 2001-02-06 | 2002-08-23 | Igaku Seibutsugaku Kenkyusho:Kk | タンパク質リン酸化酵素活性の測定方法、測定用キット及び測定に用いる抗体 |
| US20030190602A1 (en) * | 2001-03-12 | 2003-10-09 | Monogen, Inc. | Cell-based detection and differentiation of disease states |
| JP2002355048A (ja) * | 2001-05-31 | 2002-12-10 | Communication Research Laboratory | リボヌクレオチド還元酵素r1とその阻害ペプチド |
| AU2002332778A1 (en) * | 2001-08-31 | 2003-03-18 | Datascope Investment Corp. | Methods for blocking nonspecific hybridizations of nucleic acid sequences |
-
2003
- 2003-07-11 US US10/618,443 patent/US20040115692A1/en not_active Abandoned
-
2004
- 2004-07-09 BR BRPI0412030-2A patent/BRPI0412030A/pt not_active Application Discontinuation
- 2004-07-09 WO PCT/US2004/022390 patent/WO2005007872A2/en not_active Ceased
- 2004-07-09 JP JP2006518973A patent/JP2007524843A/ja active Pending
- 2004-07-09 KR KR1020057025076A patent/KR20060029633A/ko not_active Ceased
- 2004-07-09 AU AU2004258176A patent/AU2004258176B2/en not_active Ceased
- 2004-07-09 CN CNA2008101315041A patent/CN101329275A/zh active Pending
- 2004-07-09 CA CA002531002A patent/CA2531002A1/en not_active Abandoned
- 2004-07-09 CN CNB2004800186787A patent/CN100408696C/zh not_active Expired - Fee Related
- 2004-07-09 EP EP04756924A patent/EP1644525A4/en not_active Withdrawn
-
2005
- 2005-12-21 IL IL172741A patent/IL172741A0/en unknown
-
2009
- 2009-03-20 US US12/408,179 patent/US9428810B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| WO2005007872A3 (en) | 2005-04-14 |
| KR20060029633A (ko) | 2006-04-06 |
| CA2531002A1 (en) | 2005-01-27 |
| EP1644525A4 (en) | 2008-11-05 |
| EP1644525A2 (en) | 2006-04-12 |
| JP2007524843A (ja) | 2007-08-30 |
| IL172741A0 (en) | 2006-04-10 |
| AU2004258176A1 (en) | 2005-01-27 |
| AU2004258176B2 (en) | 2009-08-13 |
| CN100408696C (zh) | 2008-08-06 |
| WO2005007872A2 (en) | 2005-01-27 |
| US20090233269A1 (en) | 2009-09-17 |
| CN101329275A (zh) | 2008-12-24 |
| US20040115692A1 (en) | 2004-06-17 |
| US9428810B2 (en) | 2016-08-30 |
| CN1816634A (zh) | 2006-08-09 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| BRPI0412030A (pt) | método de ensaio, método para identificar um sensor que especificamente se liga em um alvo centrossÈmico, e, solução alcoólica conservante | |
| Tschmelak et al. | Total internal reflectance fluorescence (TIRF) biosensor for environmental monitoring of testosterone with commercially available immunochemistry: Antibody characterization, assay development and real sample measurements | |
| WO2004063700A3 (en) | Multiplex analytical platform using molecular tags | |
| ATE541054T1 (de) | Bio-barcode erkennung für zielmoleküle | |
| WO2008070865A3 (en) | Materials and methods for efficient and accurate detection of analytes | |
| BR9811406A (pt) | Dispositivo para detenção da presença de pelo menos um analito em uma amostra biológica, kit para detenção da presença de pelo menos um analito em uma amostra biológica, e, processo de detecção da presença de pelo menos um analito em uma amostra biológica | |
| WO2005089524A3 (en) | Compositions and methods for detection of single molecules | |
| SE9604575D0 (sv) | Method and system for analyte determination | |
| WO2004099434A3 (en) | Homogeneous multiplex screening assays and kits | |
| Pazos et al. | Resonant mirror biosensor detection method based on yessotoxin–phosphodiesterase interactions | |
| BR0206318A (pt) | Detecção de analitos | |
| BR0317394A (pt) | Uso de nicotinamida n-metiltransferase como um marcador para câncer colorretal | |
| Alfonso et al. | Quantification of yessotoxin using the fluorescence polarization technique and study of the adequate extraction procedure | |
| BRPI0413476A (pt) | métodos e disositivos para preparação de amostras | |
| WO2016019929A3 (en) | Method of detection of analyte active forms and determination of the ability of substances to bind into analyte active sites | |
| WO2005114218A3 (en) | Cross-screening system and methods for detecting a molecule having binding affinity for a target molecule | |
| ATE405832T1 (de) | Verfahren zur erhöhung des dynamischen messbereichs von auf spezifischen bindereaktionen basierenden, insbesondere immunologischen testelementen | |
| Lee et al. | A highly sensitive capillary electrophoresis method using p-nitrophenyl 5′-thymidine monophosphate as a substrate for the monitoring of nucleotide pyrophosphatase/phosphodiesterase activities | |
| ATE333091T1 (de) | Verfahren zur messung von blutersatzstoffen | |
| Rico-Rico et al. | Freely dissolved concentrations of anionic surfactants in seawater solutions: Optimization of the non-depletive solid-phase microextraction method and application to linear alkylbenzene sulfonates | |
| BR0314654A (pt) | Método de determinação de grupamentos especìficos que constituem as heparinas ou as heparinas de baixo peso molecular | |
| DE60138192D1 (de) | Verfahren zur quantifizierung der akt-protein-expression | |
| FR2900936B1 (fr) | Procede et methodes de detection de la maladie d'alzheimer | |
| DE60028190D1 (de) | Verfahren zur quantifizierung von cholesterin | |
| WO2009144677A4 (pt) | Perfis de compostos hidrocarbonados voláteis, marcadores de degradação/envelhecimento de material celulósico e marcadores de patologia |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
| B07G | Grant request does not fulfill article 229-c lpi (prior consent of anvisa) [chapter 7.7 patent gazette] |
Free format text: NOTIFICACAO DE DEVOLUCAO DO PEDIDO POR NAO SE ENQUADRAR NO ART. 229-C DA LPI. |
|
| B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
| B09B | Patent application refused [chapter 9.2 patent gazette] | ||
| B09B | Patent application refused [chapter 9.2 patent gazette] |
Free format text: MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL |