BRPI0412747A - processo para preparação de anidridos cìclicos de ácido fosfÈnico - Google Patents

processo para preparação de anidridos cìclicos de ácido fosfÈnico

Info

Publication number
BRPI0412747A
BRPI0412747A BRPI0412747-1A BRPI0412747A BRPI0412747A BR PI0412747 A BRPI0412747 A BR PI0412747A BR PI0412747 A BRPI0412747 A BR PI0412747A BR PI0412747 A BRPI0412747 A BR PI0412747A
Authority
BR
Brazil
Prior art keywords
phosphonic acid
cyclic
formula
anhydrides
acetic acid
Prior art date
Application number
BRPI0412747-1A
Other languages
English (en)
Inventor
Mark Wehner
Bettina Kirschbaum
Lothar Deutscher
Hans Juergen Wagner
Harald H Ssl
Original Assignee
Clariant Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Clariant Gmbh filed Critical Clariant Gmbh
Publication of BRPI0412747A publication Critical patent/BRPI0412747A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6564—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms
    • C07F9/6571—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and oxygen atoms as the only ring hetero atoms
    • C07F9/657163—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and oxygen atoms as the only ring hetero atoms the ring phosphorus atom being bound to at least one carbon atom
    • C07F9/657181—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and oxygen atoms as the only ring hetero atoms the ring phosphorus atom being bound to at least one carbon atom the ring phosphorus atom and, at least, one ring oxygen atom being part of a (thio)phosphonic acid derivative
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6564—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms
    • C07F9/6571—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and oxygen atoms as the only ring hetero atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C237/22—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton having nitrogen atoms of amino groups bound to the carbon skeleton of the acid part, further acylated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/3895—Pyrophosphonic acids; phosphonic acid anhydrides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/10—Process efficiency

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)

Abstract

"PROCESSO PARA PREPARAçãO DE ANIDRIDOS CìCLICOS DE áCIDO FOSFÈNICO". A presente invenção refere-se a um processo para preparação de anidridos cíclicos de ácido fosfónico da fórmula (III) por meio de a) reação de derivados de ácido fosfónico da fórmula (I) com anidrido de ácido acético a uma temperatura na faixa de 30 até 150<198> C e simultânea separação por destilação de uma mistura de ácido acético e anidrido de ácido acético, b) subseqüente destilação reativa dos anidridos oligómeros de ácido fosfónico da fórmula (II) obtidos na etapa a) e transformação nos anidridos cíclicos trímeros de ácido fosfónico da fórmula (III) correspondentes, sendo que n é um número inteiro de 0 até 300 e R representa alila, arila ou radicais C~ 1~ até C~ 8~-alquila de cadeia aberta cíclicos ou ramificados, arilóxi, alilóxi ou alcóxi com radicais C~ 1~ até C~ 8~-alquila de cadeia aberta cíclicos ou ramificados. Os anidridos cíclicos trímeros de ácido fosfónico formados na etapa b) são de preferência imediatamente dissolvidos em um solvente orgânico que é inerte em relação a eles.
BRPI0412747-1A 2003-07-21 2004-07-08 processo para preparação de anidridos cìclicos de ácido fosfÈnico BRPI0412747A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10333042A DE10333042B4 (de) 2003-07-21 2003-07-21 Verfahren zur Herstellung von cyclischen Phosphonsäureanhydriden und deren Verwendung
PCT/EP2004/007468 WO2005014604A2 (de) 2003-07-21 2004-07-08 Verfahren zur herstellung von cyclischen phosphonsäureanhydriden

Publications (1)

Publication Number Publication Date
BRPI0412747A true BRPI0412747A (pt) 2006-09-26

Family

ID=34111622

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0412747-1A BRPI0412747A (pt) 2003-07-21 2004-07-08 processo para preparação de anidridos cìclicos de ácido fosfÈnico

Country Status (13)

Country Link
US (2) US7473794B2 (pt)
EP (1) EP1658299B1 (pt)
JP (1) JP4757797B2 (pt)
KR (1) KR20060063906A (pt)
CN (1) CN100387606C (pt)
AT (1) ATE443710T1 (pt)
AU (1) AU2004263226A1 (pt)
BR (1) BRPI0412747A (pt)
CA (1) CA2533173A1 (pt)
DE (2) DE10333042B4 (pt)
ES (1) ES2331074T3 (pt)
MX (1) MXPA06000788A (pt)
WO (1) WO2005014604A2 (pt)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10333042B4 (de) * 2003-07-21 2005-09-29 Clariant Gmbh Verfahren zur Herstellung von cyclischen Phosphonsäureanhydriden und deren Verwendung
DE102008003677A1 (de) * 2008-01-09 2009-07-16 Archimica Gmbh Verfahren zur Herstellung von Phosphonsäureanhydriden
FR2928148B1 (fr) * 2008-02-28 2013-01-18 Sanofi Aventis Procede de preparation de combretastatine
CA2726847A1 (en) * 2008-06-09 2010-01-07 Celtic Catalysts Limited Process
EP2346885B1 (de) * 2008-11-05 2013-08-28 Clariant International Ltd. Verfahren zur herstellung von monocarboxyfunktionaslisierten dialkylphosphinsäuren, -estern und -salzen mittels allylalkoholen/acroleinen und ihre verwendung
DE102008055916A1 (de) * 2008-11-05 2010-05-06 Clariant International Limited Verfahren zur Herstellung von mono-hydroxyfunktionalisierten Dialkylphosphinsäuren, -estern und -salzen mittels Allylalkoholen und ihre Verwendung
DE102008055914A1 (de) * 2008-11-05 2010-05-06 Clariant International Limited Verfahren zur Herstellung von mono-hydroxyfunktionalisierten Dialkylphosphinsäuren, -estern und -salzen mittels Acroleinen und ihre Verwendung
EP2352740B1 (de) 2008-11-07 2014-09-24 Clariant Finance (BVI) Limited Verfahren zur herstellung von dialkylphosphinsäuren, -estern und -salzen mittels acrylsäurederivaten und ihre verwendung
DE102008056341A1 (de) * 2008-11-07 2010-05-12 Clariant International Limited Verfahren zur Herstellung von monoaminofunktionalisierten Dialkylphosphinsäuren, -estern und -salzen mittels Acrylnitrilen und ihre Verwendung
DE102008056342A1 (de) * 2008-11-07 2010-05-12 Clariant International Limited Verfahren zur Herstellung von Dialkylphosphinsäuren, -estern und -salzen mittels Acrylnitrilen und ihre Verwendung
DE102008056339A1 (de) * 2008-11-07 2010-05-12 Clariant International Limited Verfahren zur Herstellung von mono-aminofunktionalisierten Dialkylphosphinsäuren, -estern und -salzen und ihre Verwendung
JP5743219B2 (ja) 2008-11-11 2015-07-01 クラリアント・ファイナンス・（ビーブイアイ）・リミテッド アリル化合物を用いる、モノアリル官能性ジアルキルホスフィン酸、それらの塩およびエステルの製造方法およびそれらの使用
DE102008060035A1 (de) * 2008-12-02 2010-06-10 Clariant International Limited Verfahren zur Herstellung von mono-hydroxyfunktionalisierten Dialkylphosphinsäuren, -estern und -salzen mittels Vinylester einer Carbonsäure und ihre Verwendung
DE102008060036A1 (de) * 2008-12-02 2010-06-10 Clariant International Limited Verfahren zur Herstellung von mono-carboxyfunktionalisierten Dialkylphosphinsäuren, -estern und -salzen mittels Vinylester einer Carbonsäure und ihre Verwendung
DE102008060535A1 (de) 2008-12-04 2010-06-10 Clariant International Limited Verfahren zur Herstellung von mono-carboxyfunktionalisierten Dialkylphosphinsäuren, -estern und -salzen mittels Vinylether und ihre Verwendung
DE102008063627A1 (de) 2008-12-18 2010-06-24 Clariant International Limited Verfahren zur Herstellung von monohydroxyfunktionalisierten Dialkylphosphinsäuren,-estern und -salzen mittels Ethylenoxid und ihre Verwendung
ES2446666T3 (es) 2008-12-18 2014-03-10 Clariant Finance (Bvi) Limited Procedimiento para la preparación de ácidos etilen-dialquil-fosfínicos, o de sus ésteres y sales, mediante acetileno, y su utilización
DE102008063668A1 (de) * 2008-12-18 2010-07-01 Clariant International Limited Verfahren zur Herstellung von Alkylphosponsäuren, -estern und -salzen mittels Oxidation von Alkylphosphonigsäuren und ihre Verwendung
DE102008063642A1 (de) 2008-12-18 2010-06-24 Clariant International Limited Verfahren zur Herstellung von monocarboxyfunktionalisierten Dialkylphosphinsäuren, -estern und -salzen mittels Alkylenoxiden und ihre Verwendung
DE102008064012A1 (de) 2008-12-19 2010-06-24 Clariant International Limited Halogenfreie Addukte von Alkylphosphonigsäurederivaten und diesterbildenden Olefinen, halogenfreie Verfahren zu deren Herstellung und ihre Verwendung
DE102008064003A1 (de) 2008-12-19 2010-06-24 Clariant International Limited Verfahren zur Herstellung von mono-funktionalisierten Dialkylphosphinsäuren, -estern und -salzen und ihre Verwendung
CN102858739A (zh) * 2010-03-10 2013-01-02 斯索恩有限公司 酰胺化吡咯甲酸酯化合物的方法
ES2548256T3 (es) 2010-10-14 2015-10-15 Synthon Bv Proceso para la preparación de bortezomib y los intermedios para el proceso
DE102011108324A1 (de) * 2011-07-25 2013-01-31 Merck Patent Gmbh Verfahren zur Herstellung von Bis(perfluoralkyl)phosphinsäureanhydriden
CN103483386B (zh) * 2013-08-30 2016-03-02 山东汇海医药化工有限公司 一种改进的1-丙基膦酸环酐的制备方法
CN107331893B (zh) * 2016-04-29 2020-03-10 华为技术有限公司 一种高温锂离子电池电解液及其制备方法和高温锂离子电池
CN107011384B (zh) * 2017-04-24 2019-02-15 中节能万润股份有限公司 一种环状丙基膦酸酐的制备方法
WO2019038406A1 (en) 2017-08-25 2019-02-28 Synthon B.V. PROCESS FOR THE PREPARATION OF IXAZOMIB OR ITS INTERMEDIATES
CN108314693B (zh) * 2018-01-09 2020-06-09 苏州亚科科技股份有限公司 一种提高烷基膦酸酐衍生物稳定性的方法
WO2021226433A1 (en) 2020-05-08 2021-11-11 Hyconix, Inc. Process for generating acid anhydrides
CN111635434B (zh) * 2020-07-20 2023-04-07 苏州昊帆生物股份有限公司 1-丙基磷酸环酐的合成方法
CN113185622B (zh) * 2021-04-29 2022-05-24 华南理工大学 一种高磷含量壳聚糖衍生物及其制备与在负载纳米零价铁中的应用
KR102464766B1 (ko) * 2021-07-09 2022-11-07 동우 화인켐 주식회사 전해액 조성물 및 이를 포함하는 이차전지
CN114195826B (zh) * 2021-09-13 2023-06-23 洪湖市一泰科技有限公司 一种环膦酸酐生产中的蒸馏釜残留物的处理方法及处理装置
CN114763364A (zh) * 2021-11-18 2022-07-19 黑龙江豪运药业有限公司 一种1-丙基磷酸酐的合成方法
CN115253339B (zh) * 2022-07-21 2024-04-12 西安彩晶光电科技股份有限公司 一种1-丙基磷酸环酐的生产装置及工艺

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2758580A1 (de) 1977-12-29 1979-07-05 Hoechst Ag Verfahren zur herstellung von phosphin- und phosphonsaeure-anhydriden
DE2811628A1 (de) * 1978-03-17 1979-09-27 Hoechst Ag Alkan-bis-alkyl-phosphinsaeureanhydride und verfahren zur herstellung von alkanphosphon- und alkan-bis-alkylphosphinsaeureanhydriden
DE3411224A1 (de) * 1984-03-27 1985-10-10 Hoechst Ag, 6230 Frankfurt Verfahren zur racematarmen herstellung von peptidzwischenprodukten der gonadorelin- und gonadorelinanaloga-synthese und neue zwischenprodukte bei diesem verfahren
JPH01279921A (ja) * 1988-05-06 1989-11-10 Idemitsu Kosan Co Ltd ポリアミドの製造方法
US5191065A (en) * 1988-11-22 1993-03-02 Hoechst Aktiengesellschaft Process for the preparation of tripeptides
US5319138A (en) * 1991-08-08 1994-06-07 Hoechst Aktiengesellschaft Process for the preparation of pure propanephosphonic anhydride
JPH0686478A (ja) 1991-08-29 1994-03-25 Nec Home Electron Ltd 電子機器
JPH09157284A (ja) * 1995-12-11 1997-06-17 Ono Pharmaceut Co Ltd グルコピラノース誘導体の製造方法
DE19802969A1 (de) * 1998-01-27 1999-07-29 Hoechst Marion Roussel De Gmbh Verfahren zur Herstellung von S-Alkyl(Aryl)-substituierten Imidazol-Derivaten
DE10063493A1 (de) 2000-12-20 2002-06-27 Bayer Ag Verfahren zur Herstellung von substituierten Arylketonen
DE10333042B4 (de) * 2003-07-21 2005-09-29 Clariant Gmbh Verfahren zur Herstellung von cyclischen Phosphonsäureanhydriden und deren Verwendung

Also Published As

Publication number Publication date
EP1658299A2 (de) 2006-05-24
WO2005014604A3 (de) 2005-05-06
ATE443710T1 (de) 2009-10-15
MXPA06000788A (es) 2006-04-18
JP2006528140A (ja) 2006-12-14
DE10333042A1 (de) 2005-03-03
ES2331074T3 (es) 2009-12-21
US20060264654A1 (en) 2006-11-23
CN100387606C (zh) 2008-05-14
DE10333042B4 (de) 2005-09-29
US7473794B2 (en) 2009-01-06
JP4757797B2 (ja) 2011-08-24
EP1658299B1 (de) 2009-09-23
HK1093989A1 (zh) 2007-03-16
WO2005014604A2 (de) 2005-02-17
US7829736B2 (en) 2010-11-09
CN1823079A (zh) 2006-08-23
KR20060063906A (ko) 2006-06-12
AU2004263226A1 (en) 2005-02-17
CA2533173A1 (en) 2005-02-17
US20080183009A1 (en) 2008-07-31
DE502004010124D1 (de) 2009-11-05

Similar Documents

Publication Publication Date Title
BRPI0412747A (pt) processo para preparação de anidridos cìclicos de ácido fosfÈnico
BR0307701A (pt) Componente de catalisador sólido para polimerização de olefinas, o catalisador compreendendo tal componente e uso do mesmo
BRPI0601311A (pt) mercaptosilanos
RU2011133749A (ru) Способ получения и выделения 2-ациламино-3-дифенилпропионовой кислоты
EA200200098A1 (ru) Ароматические сложные эфиры для маркировки или мечения нефтепродуктов
ATE552244T1 (de) 1-h-benzoägüindol- verbindungen und sie enthaltende organische lichtemittierende vorrichtung
BR9901298A (pt) Novos compostos de benzotiofeno, benzofurano e indol, um processo para sua preparação e composições farmacêuticas que os contêm
BRPI0408160A (pt) processo para o preparo de ésteres do ácido nicotìnico substituìdo
BR112012031406A2 (pt) processo para a preparação de derivados de di-hidropirrol
BRPI0406500A (pt) processo farmacêutico e compostos preparados pelo mesmo
BRPI0800988A2 (pt) compostos tricÍclicos, processo para sua preparaÇço e composiÇÕes farmacÊuticas contendo-os
CA2348695A1 (en) Method of preparing delta-9-tetrahydrocannabinol esters
BRPI0408365A (pt) compostos heterocìclicos de imunomodulação
ATE500711T1 (de) Phenanthrolinverbindungen und elektrolumineszensbauelemente damit
BR0211291A (pt) Derivados de diamina, processo para produção dos derivados de diamina e fungicidas contendo os derivados de diamina como ingrediente ativo
BR0215776A (pt) Processo para a preparação de derivados de pename a partir de derivados de cefame
BRPI0412904A (pt) processo para a preparação de inibidores de cpla2
NO20020052L (no) Fremgangsmåte for fremstilling av nitroksymetylfenylestere av salisylsyrederivater
BR0311469A (pt) Composto de monÈmero que compreende diversos grupos catiÈnicos e polìmeros que compreendem unidades obtidas a partir deste
BRPI0511109A (pt) método fácil para sintetizar compostos de baccatin iii
BRPI0212411B8 (pt) &#39; processos para reduzir os níveis de solventes orgânicos em um sólido de carbapenem, e para fabricar um hidrato cristalino&#39;
CN107033106B (zh) 一种磺酰胺类化合物的制备方法
AR038746A1 (es) Compuestos organicos
DE69424095D1 (de) Verfahren zur Herstellung von 2-Cyano-4-oxo-4H-benzopyran-Verbindungen
BR0214173A (pt) Processo para reagir alcalóides, produto de reação, mistura de produtos de reação, e, uso de produtos de reação

Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE AS 5A, 6A, 7A E 8A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2159 DE 22/05/2012.