BRPI0413101A - compostos de sulfonamida derivado de benzoxazinona, sua preparação e uso como medicamentos - Google Patents

compostos de sulfonamida derivado de benzoxazinona, sua preparação e uso como medicamentos

Info

Publication number
BRPI0413101A
BRPI0413101A BRPI0413101-0A BRPI0413101A BRPI0413101A BR PI0413101 A BRPI0413101 A BR PI0413101A BR PI0413101 A BRPI0413101 A BR PI0413101A BR PI0413101 A BRPI0413101 A BR PI0413101A
Authority
BR
Brazil
Prior art keywords
preparation
benzoxazinone
sulfonamide compounds
medicines
compounds
Prior art date
Application number
BRPI0413101-0A
Other languages
English (en)
Inventor
Antoni Torrens Jover
Josep Mas Prio
Alberto Dordal Zueras
Maria Angeles Fisas Escasany
Original Assignee
Esteve Labor Dr
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Esteve Labor Dr filed Critical Esteve Labor Dr
Publication of BRPI0413101A publication Critical patent/BRPI0413101A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/536—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines ortho- or peri-condensed with carbocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Diabetes (AREA)
  • Epidemiology (AREA)
  • Psychiatry (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Psychology (AREA)
  • Endocrinology (AREA)
  • Hospice & Palliative Care (AREA)
  • Emergency Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Child & Adolescent Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

"COMPOSTOS DE SULFONAMIDA DERIVADO DE BENZOXAZINONA, SUA PREPARAçãO E USO COMO MEDICAMENTOS". A presente invenção se relaciona a compostos de sulfonamida derivados de benzoxazinona de fórmula geral (I), um processo para sua preparação, um medicamento que compreende esses compostos e o uso dos compostos de sulfonamida derivados de benzoxazinona para a preparação de medicamentos para regulação de receptor 5-HT~ 6~ assim como para o tratamento de distúrbios relacionados a eles.
BRPI0413101-0A 2003-07-30 2004-07-29 compostos de sulfonamida derivado de benzoxazinona, sua preparação e uso como medicamentos BRPI0413101A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ES200301812A ES2232292B1 (es) 2003-07-30 2003-07-30 Compuestos sulfonamidicos derivados de benzoxazinona, su preparacion y uso como medicamentos.
PCT/EP2004/008507 WO2005014589A1 (en) 2003-07-30 2004-07-29 Benzoxazinone-derived sulfonamide compounds, their preparation and use as medicaments

Publications (1)

Publication Number Publication Date
BRPI0413101A true BRPI0413101A (pt) 2006-10-03

Family

ID=34130545

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0413101-0A BRPI0413101A (pt) 2003-07-30 2004-07-29 compostos de sulfonamida derivado de benzoxazinona, sua preparação e uso como medicamentos

Country Status (23)

Country Link
US (1) US20070032482A1 (pt)
EP (1) EP1648886B1 (pt)
JP (1) JP2007500161A (pt)
KR (1) KR20060056355A (pt)
CN (1) CN1860114A (pt)
AR (1) AR045153A1 (pt)
AT (1) ATE451366T1 (pt)
AU (1) AU2004263300A1 (pt)
BR (1) BRPI0413101A (pt)
CA (1) CA2534095A1 (pt)
CL (1) CL2004001929A1 (pt)
DE (1) DE602004024538D1 (pt)
EC (1) ECSP066331A (pt)
ES (2) ES2232292B1 (pt)
IL (1) IL173004A0 (pt)
MX (1) MXPA06001228A (pt)
NO (1) NO20060969L (pt)
PE (1) PE20050724A1 (pt)
PT (1) PT1648886E (pt)
RU (1) RU2006105714A (pt)
TW (1) TW200510354A (pt)
WO (1) WO2005014589A1 (pt)
ZA (1) ZA200600426B (pt)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2005250336B2 (en) * 2004-04-20 2011-06-09 Amgen, Inc. Arylsulfonamides and uses as hydroxysteroid dehydrogenase
AR058277A1 (es) 2005-12-09 2008-01-30 Solvay Pharm Gmbh N- sulfamoil - piperidin - amidas, composiciones farmaceuticas que las comprenden y procedimiento para su preparacion
GB2435825A (en) * 2006-03-09 2007-09-12 Esteve Labor Dr Benzimidazole-2- & pyrido[d]imidazole-2- sulphonamide derivatives for treatment of disorders mediated via 5-HT6 receptors, eg those related to food intake
EP2053052A1 (en) 2007-10-23 2009-04-29 Laboratorios del Dr. Esteve S.A. Process for the preparation of 6-substituted imidazo[2,1-b]thiazole-5-sulfonyl halide
JP7113810B2 (ja) 2016-07-07 2022-08-05 ブリストル－マイヤーズ スクイブ カンパニー Ｒｏｃｋ阻害剤としてのスピロラクタム
SG11202000833YA (en) * 2017-08-07 2020-02-27 Suven Life Sciences Ltd Fluoropiperidine compounds as pure 5-ht6 receptor antagonists
GB201713780D0 (en) * 2017-08-29 2017-10-11 E-Therapeutics Plc Modulators of hedgehog (Hh) signalling pathway
CN109232599B (zh) * 2018-10-08 2021-04-20 广西中医药大学 具有抗肿瘤活性的o-对三氟甲基苯甲酰基土甘草a及其制备方法和用途

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4344945A (en) * 1980-03-10 1982-08-17 Kyowa Hakko Kogyo Co., Ltd. Piperidine derivatives
TW199153B (pt) * 1990-08-07 1993-02-01 Dtsuka Seiyaku Kk
AU691829B2 (en) * 1993-07-16 1998-05-28 Merck & Co., Inc. Benzoxazinone and benzopyrimidinone piperidinyl tocolytic oxytocin receptor antagonists
ES2271967T3 (es) * 1996-03-29 2007-04-16 Duphar International Research B.V Compuestos de piperazina y piperidina.
ES2191180T3 (es) * 1996-05-29 2003-09-01 Warner Lambert Co Antagonistas de los receptores de la dopamina benzoxazinona d4.
SE9904652D0 (sv) * 1999-12-17 1999-12-17 Astra Pharma Prod Novel Compounds
ATE255578T1 (de) * 2000-05-12 2003-12-15 Solvay Pharm Bv Piperazin- und piperidinverbindungen

Also Published As

Publication number Publication date
US20070032482A1 (en) 2007-02-08
AR045153A1 (es) 2005-10-19
MXPA06001228A (es) 2006-05-15
ATE451366T1 (de) 2009-12-15
ZA200600426B (en) 2007-03-28
CL2004001929A1 (es) 2005-06-03
KR20060056355A (ko) 2006-05-24
ES2232292A1 (es) 2005-05-16
JP2007500161A (ja) 2007-01-11
CN1860114A (zh) 2006-11-08
ECSP066331A (es) 2006-08-30
ES2338008T3 (es) 2010-05-03
RU2006105714A (ru) 2007-09-20
EP1648886B1 (en) 2009-12-09
WO2005014589A1 (en) 2005-02-17
AU2004263300A1 (en) 2005-02-17
PT1648886E (pt) 2010-03-10
IL173004A0 (en) 2006-06-11
EP1648886A1 (en) 2006-04-26
NO20060969L (no) 2006-04-11
DE602004024538D1 (de) 2010-01-21
ES2232292B1 (es) 2006-11-01
PE20050724A1 (es) 2005-11-16
CA2534095A1 (en) 2005-01-27
TW200510354A (en) 2005-03-16

Similar Documents

Publication Publication Date Title
BR0315296A (pt) Derivados do ciclohexanol espirocìclicos
BR0312513A (pt) Derivados de glicosìdeo de tiofeno, processos para a produção dos mesmos, medicamentos que contêm esses compostos e uso dos mesmos
BR0312729A (pt) Novos derivados de indol-3-enxofre
BR0214243A (pt) Derivado de sulfonamida processo para a preparação de um derivado de sulfonamida e seus sais fisiologicamente aceitáveis, composição farmacêutica e uso de um derivado de sulfonamida
BRPI0409109A (pt) novos compostos
AR035348A1 (es) Indoles sustituidos, composiciones farmaceuticas que los comprenden, y uso de dichos compuestos en la preparacion de medicamentos
BR0112589A (pt) Derivados de heteroarila e sua aplicação como medicamento
CU23105A3 (es) DERIVADOS NOVEDOSOS DEL áCIDO AMINODICARBOXILICO CON PROPIEDADES FARMACéUTICAS
BR0112591A (pt) Derivados de acridina e sua aplicação como medicamento
BR0313676A (pt) Derivados de pirimidina e uso destes como moduladores cb2
BR0210711A (pt) Uso de um composto, composição farmacêutica, composto, e, processo para a preparação de um composto
BR0308653A (pt) Cristais de derivado de benzeno de glicopiranosiloxibenzila
BR0314393A (pt) Piperazinas heterocìclicas substituìdas para o tratamento de esquizofrenia
BR0309083A (pt) Compostos derivados de benzoxazinona, sua preparação e uso como medicamentos
PT1506185E (pt) Compostos novos e sua utilizacao
BRPI0407097A (pt) Antagonista do casr
PT1414816E (pt) Polimorfo estavel da flibanserina, processo tecnico para a sua preparacao e sua utilizacao na preparacao de medicamentos
BRPI0409498A (pt) uso de um composto, formulação farmacêutica, composto, composição farmacêutica, e, processo para preparação de um composto
EA200601194A1 (ru) Новые производные бензофурана, используемые для профилактики или лечения нарушений, связанных с 5-ht-рецептором
BRPI0511874A (pt) derivados da pirrolopiridina
CL2008001820A1 (es) Compuestos derivados de aril-isoxasol-imidazol; procedimiento de preparacion; composicion farmaceutica que los contiene; y uso en la preparacion de medicamentos utiles en el tratamiento de trastornos cognitivos y enfermedades relacionadas con alzheimer.
AR012504A1 (es) Utilizacion de derivados de tetrahidropiridina, para la preparacion de medicamentos para el tratamiento de las enfermedades que provocan unadesmielinizacion.
BRPI0508724A (pt) derivados do fenilaminoetanol como agonistas do receptor beta2
BR0314195A (pt) Derivados de piridina substituìda como agentes antitumorais
BR0112807A (pt) Derivados de indol e sua aplicação como medicamento

Legal Events

Date Code Title Description
B11A Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing
B11Y Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette]