BRPI0413744A - n-aril-2-ciano-oxazolidinonas e seus derivados - Google Patents

n-aril-2-ciano-oxazolidinonas e seus derivados

Info

Publication number
BRPI0413744A
BRPI0413744A BRPI0413744-2A BRPI0413744A BRPI0413744A BR PI0413744 A BRPI0413744 A BR PI0413744A BR PI0413744 A BRPI0413744 A BR PI0413744A BR PI0413744 A BRPI0413744 A BR PI0413744A
Authority
BR
Brazil
Prior art keywords
oxazolidinones
cyano
aryl
derivatives
formulas
Prior art date
Application number
BRPI0413744-2A
Other languages
English (en)
Inventor
Robert Charles Gadwood
Jason Matthew Ochoada
Original Assignee
Pharmacia & Upjohn Co Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia & Upjohn Co Llc filed Critical Pharmacia & Upjohn Co Llc
Publication of BRPI0413744A publication Critical patent/BRPI0413744A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/06—Antibacterial agents for tuberculosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D263/34—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/36—One oxygen atom
    • C07D263/38—One oxygen atom attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing aromatic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Veterinary Medicine (AREA)
  • Oncology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

"N-ARIL-2-CIANO-OXAZOLIDINONAS E SEUS DERIVADOS". A presente invenção proporciona agentes antibacterianos com as fórmulas I, II e III aqui descritas.
BRPI0413744-2A 2003-08-22 2004-08-09 n-aril-2-ciano-oxazolidinonas e seus derivados BRPI0413744A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US49718103P 2003-08-22 2003-08-22
PCT/IB2004/002616 WO2005019213A1 (en) 2003-08-22 2004-08-09 N-aryl-2-cyanooxazolidinones and their derivatives

Publications (1)

Publication Number Publication Date
BRPI0413744A true BRPI0413744A (pt) 2006-10-24

Family

ID=34216090

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0413744-2A BRPI0413744A (pt) 2003-08-22 2004-08-09 n-aril-2-ciano-oxazolidinonas e seus derivados

Country Status (7)

Country Link
US (1) US20050075382A1 (pt)
EP (1) EP1658286A1 (pt)
JP (1) JP2007503385A (pt)
BR (1) BRPI0413744A (pt)
CA (1) CA2535796A1 (pt)
MX (1) MXPA06002029A (pt)
WO (1) WO2005019213A1 (pt)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20080110877A (ko) 2006-03-31 2008-12-19 재단법인 이쯔우 연구소 헤테로환을 갖는 신규 화합물
JP5455906B2 (ja) 2007-08-06 2014-03-26 ミクウルク ファーマシューティカルズ，インコーポレイテッド 細菌感染症治療のための抗微生物性オルト−フルオロフェニルオキサゾリジノン
CN101883768A (zh) 2007-10-02 2010-11-10 财团法人乙卯研究所 具有7元杂环的噁唑烷酮衍生物
DK2630371T4 (da) 2010-10-18 2021-12-20 Vestas Wind Sys As Vindmølleeffekttransmissionssystem
US9382276B2 (en) 2014-02-21 2016-07-05 Micurx Pharmaceuticals, Inc. Water-soluble O-carbonyl phosphoramidate prodrugs for therapeutic administration
CN111559985A (zh) * 2020-05-13 2020-08-21 河南科技大学第一附属医院 具有杀菌作用的噁唑酮类化合物及其制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20010021645A (ko) * 1997-07-11 2001-03-15 로렌스 티. 마이젠헬더 티아디아졸릴 및 옥사디아졸릴 페닐 옥사졸리디논 항균제
DE10027768A1 (de) * 2000-06-07 2001-12-13 Bayer Ag Verzweigte Copolymere auf Basis von ungesättigten Nitrilen und konjugierten Dienen
AU2002255803B2 (en) * 2001-04-20 2008-07-03 Pharmacia And Upjohn Company Process to prepare oxazolidinones
DE60304360T2 (de) * 2002-08-12 2006-11-16 Pharmacia & Upjohn Co. Llc, Kalamazoo N-aryl-2-oxazolidinone und deren derivate

Also Published As

Publication number Publication date
MXPA06002029A (es) 2006-05-17
WO2005019213A1 (en) 2005-03-03
JP2007503385A (ja) 2007-02-22
US20050075382A1 (en) 2005-04-07
EP1658286A1 (en) 2006-05-24
CA2535796A1 (en) 2005-03-03

Similar Documents

Publication Publication Date Title
BR0307924A (pt) N-aril-2-oxazolidinona-5-carboxamidas e seus derivados
BR9916798A (pt) 4-arilamino, 4-arilóxi e 4-ariltio diarilaminas e seus derivados como inibidores seletivos de mek
BR0205890A (pt) Pirazolopirimidinas como agentes terapêuticos
CY1116784T1 (el) Αντιμικροβιακες ενωσεις και μεθοδοι για χρηση αυτων
NO20052787D0 (no) N-alkyl-4-metylenamino-3-hydroksy-2-pyridoner som antimikrobielle midler
DE60221684D1 (de) Antibiotika mit doppelwirkung
CY1108409T1 (el) Υβριδικα αντιβιοτικα οξαζολιδινονης-κινολονης
NO20051082L (no) Antimikrobielle kinoloner, deres sammensetninger og anvendelser
CY1106247T1 (el) Θειοφαινο- και θειαζολοσουλφοναμιδες ως αντινεοπλαστικοι παραγοντες
TR200003384T2 (tr) Arginin türevleri kullanılarak oksazolidinon antibakteriyel maddelerin etkisinin arttırılması
BR0010982A (pt) Novas oxazolidinonas bicìclicas como agentes antibacterianos
MY136297A (en) Piperazine derivatives having sst1 antagonistic activity
UA83266C2 (en) Oxazole derivatives of tetracyclines
TW200602295A (en) Organic compounds
NO20052788L (no) N-sulfonyl-4-metylenamino-3-hydroksy-2-pyridoner som antimikrobielle midler
BRPI0413744A (pt) n-aril-2-ciano-oxazolidinonas e seus derivados
DE69936052D1 (de) N1 modifizierte glycopeptide
DE60129600D1 (de) Pleuromutilinderivate mit antimikrobieller wirkung
BR0313400A (pt) N-aril-2-oxazolidinonas e seus derivados
BRPI0409143A (pt) n-aril-2-oxazolidinona-5-carboxamidas e seus derivados
PT1268475E (pt) Novos agentes bacterianos de benzosultam-oxazolidinona
BRPI0412360A (pt) compostos de organossilìcio e seu uso
TR200100475T2 (tr) N-İkameli azabisikloheptan türevlerinin üretimleri ve kullanımları.
IS8034A (is) Imídasó[4,5-B]kínólínafleiður og notkun þeirra sem NO-myndunarhemla
CY1110139T1 (el) Γλυκοπεπτιδικα αντιβιοτικα

Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE AS 5A, 6A E 7A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2159 DE 22/05/2012.