DK0920421T3 - Isoxazolinderivater anvendelige som antimikrobielle midler - Google Patents

Isoxazolinderivater anvendelige som antimikrobielle midler

Info

Publication number
DK0920421T3
DK0920421T3 DK97937156T DK97937156T DK0920421T3 DK 0920421 T3 DK0920421 T3 DK 0920421T3 DK 97937156 T DK97937156 T DK 97937156T DK 97937156 T DK97937156 T DK 97937156T DK 0920421 T3 DK0920421 T3 DK 0920421T3
Authority
DK
Denmark
Prior art keywords
antimicrobial agents
derivatives useful
isoxazoline derivatives
isoxazoline
useful
Prior art date
Application number
DK97937156T
Other languages
English (en)
Inventor
Michael R Barbachyn
Richard C Thomas
Gary J Cleek
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Application granted granted Critical
Publication of DK0920421T3 publication Critical patent/DK0920421T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
    • C07D261/04—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
DK97937156T 1996-08-21 1997-08-15 Isoxazolinderivater anvendelige som antimikrobielle midler DK0920421T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US2428796P 1996-08-21 1996-08-21
PCT/US1997/013934 WO1998007708A1 (en) 1996-08-21 1997-08-15 Isoxazoline derivatives useful as antimicrobials

Publications (1)

Publication Number Publication Date
DK0920421T3 true DK0920421T3 (da) 2003-03-10

Family

ID=21819822

Family Applications (1)

Application Number Title Priority Date Filing Date
DK97937156T DK0920421T3 (da) 1996-08-21 1997-08-15 Isoxazolinderivater anvendelige som antimikrobielle midler

Country Status (10)

Country Link
US (2) US5990136A (da)
EP (1) EP0920421B1 (da)
JP (1) JP2000516245A (da)
AT (1) ATE227277T1 (da)
AU (1) AU3973697A (da)
DE (1) DE69716925T2 (da)
DK (1) DK0920421T3 (da)
ES (1) ES2186916T3 (da)
PT (1) PT920421E (da)
WO (1) WO1998007708A1 (da)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9601666D0 (en) * 1996-01-27 1996-03-27 Zeneca Ltd Chemical compounds
GB9609919D0 (en) * 1996-05-11 1996-07-17 Zeneca Ltd Chemical compounds
FI19992555A7 (fi) 1997-05-30 1999-11-30 Upjohn Co Antibakteerisia oksatosolidinoniaineita, joilla on tiokarbonyylifunktionaalisuus
US6255304B1 (en) 1997-05-30 2001-07-03 Pharmacia & Upjohn Company Oxazolidinone antibacterial agents having a thiocarbonyl functionality
GB9717804D0 (en) 1997-08-22 1997-10-29 Zeneca Ltd Chemical compounds
GB9717807D0 (en) 1997-08-22 1997-10-29 Zeneca Ltd Chemical compounds
GB9725244D0 (en) 1997-11-29 1998-01-28 Zeneca Ltd Chemical compounds
PT1054874E (pt) * 1998-02-13 2003-01-31 Upjohn Co Derivados de aminofenil-isoxazolina substituidos uteis como anti-microbianos
JP2002504550A (ja) * 1998-02-25 2002-02-12 ファルマシア・アンド・アップジョン・カンパニー 抗微生物剤として有用な置換アミノメチルイソオキサゾリン誘導体
EP1082323A2 (en) 1998-06-05 2001-03-14 AstraZeneca UK Limited Oxazolidinone derivatives, process for their preparation and pharmaceutical compositions containing them
US6420349B1 (en) 1998-08-24 2002-07-16 Bristol-Myers Squibb Company Isoxazolinone antibacterial agents
TW572757B (en) * 1998-08-24 2004-01-21 Bristol Myers Squibb Co Novel isoxazolinone antibacterial agents
GB9928568D0 (en) * 1999-12-03 2000-02-02 Zeneca Ltd Chemical compounds
GB0009803D0 (en) 2000-04-25 2000-06-07 Astrazeneca Ab Chemical compounds
US6465456B2 (en) 2000-06-29 2002-10-15 Bristol-Myers Squibb Company Isoxazolinone antibacterial agents
EP1349853B1 (en) 2000-12-21 2006-03-08 Pharmacia & Upjohn Company LLC Antimicrobial quinolone derivatives and use of the same to treat bacterial infections
KR20030077558A (ko) * 2000-12-26 2003-10-01 재단법인 이쯔우 연구소 트로폴론 유도체
JP2005512975A (ja) 2001-10-25 2005-05-12 アストラゼネカ アクチボラグ 抗菌薬として有用なイソキサゾリン誘導体
US7141588B2 (en) * 2002-02-25 2006-11-28 Pfizer, Inc. N-aryl-2-oxazolidinone-5-carboxamides and their derivatives
AR038536A1 (es) * 2002-02-25 2005-01-19 Upjohn Co N-aril-2-oxazolidinona-5- carboxamidas y sus derivados
CA2515311A1 (en) * 2003-02-07 2004-08-19 Warner-Lambert Company Llc Antibacterial agents
JP2006516989A (ja) * 2003-02-07 2006-07-13 ワーナー−ランバート・カンパニー、リミテッド、ライアビリティ、カンパニー 抗菌剤として使用するための二環式環によりｎ−置換されたオキサゾリジノン誘導体
US7304050B2 (en) * 2003-09-16 2007-12-04 Pfizer Inc. Antibacterial agents
WO2005082900A2 (en) * 2004-01-28 2005-09-09 Pharmacia & Upjohn Company Llc Oxazolidinone amidoximes as antibacterial agents
US20080262056A1 (en) * 2004-08-06 2008-10-23 Pfizer Inc Oxindole Oxazolidinones as Antibacterial Agents
WO2006031631A1 (en) * 2004-09-10 2006-03-23 Syngenta Limited Substituted isoxazoles as fungicides
ES2682303T3 (es) * 2010-08-05 2018-09-19 Zoetis Services Llc Derivados de isoxazolina como agentes antiparasitarios
WO2012087833A1 (en) 2010-12-22 2012-06-28 Abbott Laboratories Hepatitis c inhibitors and uses thereof
AU2013327663B2 (en) * 2012-10-03 2016-03-10 Shell Internationale Research Maatschappij B.V. Optimizing performance of a drilling assembly
WO2021000297A1 (en) * 2019-07-03 2021-01-07 Merck Sharp & Dohme Corp. Compounds and methods of use thereof as antibacterial agents

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL137326C (da) * 1967-08-26
US4283403A (en) * 1976-06-14 1981-08-11 Eli Lilly And Company Substituted isoxazolines for control of plant phytopathogens
US4948801A (en) * 1988-07-29 1990-08-14 E. I. Du Pont De Nemours And Company Aminomethyloxooxazolidinyl arylbenzene derivatives useful as antibacterial agents
DE69316240T2 (de) * 1992-12-08 1998-05-20 Upjohn Co Durch eine tropon gruppe substituierte phenyloxazolidinone-derivate als antibakterielles mittel
JP2818820B2 (ja) * 1993-11-26 1998-10-30 ファイザー・インク． 抗炎症剤としての３−アリール−２−イソオキサゾリン類
DE4425613A1 (de) * 1994-07-20 1996-01-25 Bayer Ag 5-gliedrige Heteroaryl-oxazolidinone
DE4425612A1 (de) * 1994-07-20 1996-04-04 Bayer Ag 6-gliedrige stickstoffhaltige Heteroaryl-oxazolidinone
US5710159A (en) * 1996-05-09 1998-01-20 The Dupont Merck Pharmaceutical Company Integrin receptor antagonists

Also Published As

Publication number Publication date
EP0920421A1 (en) 1999-06-09
DE69716925D1 (de) 2002-12-12
JP2000516245A (ja) 2000-12-05
EP0920421B1 (en) 2002-11-06
WO1998007708A1 (en) 1998-02-26
ES2186916T3 (es) 2003-05-16
ATE227277T1 (de) 2002-11-15
US6093736A (en) 2000-07-25
DE69716925T2 (de) 2003-09-11
AU3973697A (en) 1998-03-06
US5990136A (en) 1999-11-23
PT920421E (pt) 2003-03-31

Similar Documents

Publication Publication Date Title
PT920421E (pt) Derivados de isoxazolina uteis como agentes antimicrobianos
DE69829846D1 (de) Antibakteriell wirksam oxazolidinone mit einer thiocarbonylfunktionalität
DK0869949T3 (da) Benzoxaziner som antimikrobielle midler
NO20006323L (no) Glykopeptid-derivater og farmasöytiske sammensetninger som inneholder disse
UY26551A1 (es) " agentes antibacterianos de 3-aminoquinazolin-2,4,dionas".
PT1453512E (pt) Derivados de acetileno tendo actividade antagonistica do mglur 5
DK0977741T3 (da) Substituerede phenylderivater, deres fremstilling og anvendelse
EA200300050A1 (ru) Гликопептидфосфонатные производные
DK1930330T3 (da) Pleuromutilinderivater som antimikrobielle midler
ATE376996T1 (de) Antibakterielle mittel
DE60118885D1 (de) Nitratsalze von antimikrobiellen wirkstoffen
NO20022888L (no) Lipopeptider som antibakterielle midler
ID29076A (id) Kombinasi senyawa aktif fungisida
NO20022887L (no) Lipopeptider som antibakterielle midler
ES2243579T3 (es) Derivados de pirazolopirideno.
WO2003053971A8 (en) Pyridoquinoxaline antivirals
BR0010982A (pt) Novas oxazolidinonas bicìclicas como agentes antibacterianos
ES2178765T3 (es) Nuevos derivados de 1,7,7-trimetil-biciclo (2.2.1) heptano.
UA83266C2 (en) Oxazole derivatives of tetracyclines
EA200500353A1 (ru) Производные линкомицина, обладающие антибактериальной активностью
AR025379A1 (es) 9a-azalidas con actividad antibacteriana.
DE69936052D1 (de) N1 modifizierte glycopeptide
PT1268475E (pt) Novos agentes bacterianos de benzosultam-oxazolidinona
TW200420561A (en) Antimicrobial 1-aryl dihydropyridone compounds
AU2003259159A1 (en) N-aryl-2-oxazolidinones and their derivatives