BRPI0414402A - moduladores de ligante 1 de glicoproteìna p-selectina - Google Patents

moduladores de ligante 1 de glicoproteìna p-selectina

Info

Publication number
BRPI0414402A
BRPI0414402A BRPI0414402-3A BRPI0414402A BRPI0414402A BR PI0414402 A BRPI0414402 A BR PI0414402A BR PI0414402 A BRPI0414402 A BR PI0414402A BR PI0414402 A BRPI0414402 A BR PI0414402A
Authority
BR
Brazil
Prior art keywords
cells
selectin glycoprotein
modulators
binder
cell
Prior art date
Application number
BRPI0414402-3A
Other languages
English (en)
Inventor
Rong-Hwa Lin
Chung Nan Chang
Original Assignee
Abgenomics Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US10/662,906 external-priority patent/US20040116333A1/en
Application filed by Abgenomics Corp filed Critical Abgenomics Corp
Publication of BRPI0414402A publication Critical patent/BRPI0414402A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2896—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against molecules with a "CD"-designation, not provided for elsewhere
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/7056—Lectin superfamily, e.g. CD23, CD72
    • C07K14/70564—Selectins, e.g. CD62
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/75—Agonist effect on antigen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Toxicology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Cell Biology (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

"MODULADORES DE LIGANTE 1 DE GLICOPROTEìNA P-SELECTINA". A presente invenção refere-se a compostos multiméricos que se ligam à Glicoproteína P-Selectina (PSGL-1) sobre a superfície de células T ou células exterminadoras naturais (NK), e podem ser usados para induzir a depleção de células T ou células NK, e/ou para induzir a apoptose de células T ou células NK. Os compostos multiméricos e os métodos da invenção podem ser usados para controlar respostas imunes indesejadas, mediadas por células T ou células NK, em condições tais como doenças inflamatórias, doenças auto-imunes, rejeição a transplantes, e doenças alérgicas.
BRPI0414402-3A 2003-09-15 2004-09-09 moduladores de ligante 1 de glicoproteìna p-selectina BRPI0414402A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10/662,906 US20040116333A1 (en) 2001-08-03 2003-09-15 Modulators of P-selectin glycoprotein ligand 1
PCT/US2004/029520 WO2005027831A2 (en) 2001-08-03 2004-09-09 Modulators of p-selectin glycoprotein ligand 1

Publications (1)

Publication Number Publication Date
BRPI0414402A true BRPI0414402A (pt) 2006-11-14

Family

ID=36242362

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0414402-3A BRPI0414402A (pt) 2003-09-15 2004-09-09 moduladores de ligante 1 de glicoproteìna p-selectina

Country Status (16)

Country Link
EP (1) EP1663290A4 (pt)
JP (1) JP5808879B2 (pt)
KR (1) KR101159140B1 (pt)
CN (1) CN1852730B (pt)
AU (1) AU2004273807B2 (pt)
BR (1) BRPI0414402A (pt)
CA (1) CA2538284C (pt)
EC (1) ECSP066507A (pt)
IL (1) IL174172A (pt)
NO (1) NO20061306L (pt)
NZ (1) NZ546203A (pt)
RU (1) RU2407539C2 (pt)
SG (1) SG146670A1 (pt)
TW (2) TW201012472A (pt)
UA (1) UA91004C2 (pt)
ZA (1) ZA200602151B (pt)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2655833T3 (es) * 2004-05-11 2018-02-21 AbGenomics Coöperatief U.A. Epítopos que inducen la muerte de células T
JP5493234B2 (ja) * 2008-05-15 2014-05-14 国立大学法人 岡山大学 Ｐｓｇｌ−１阻害によるメタボリックシンドロームの予防及び治療法
IL260289B (en) * 2016-01-08 2022-08-01 Bioalliance Cv Tetravalent anti-psgl-1 antibodies and uses thereof
CN115887659A (zh) * 2022-11-23 2023-04-04 中山大学附属第七医院(深圳) 终末耗竭t细胞群“tcf19+pd1+tim3+cd8+”的鉴定及应用
CN121108302A (zh) * 2025-09-22 2025-12-12 渼达(广州)生物科技有限公司 一种重组人Fc和P-选择素的重组蛋白、检测产品及其制备方法和应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0368684B2 (en) * 1988-11-11 2004-09-29 Medical Research Council Cloning immunoglobulin variable domain sequences.
US5843707A (en) * 1992-10-23 1998-12-01 Genetics Institute, Inc. Nucleic acid encoding a novel P-selectin ligand protein
US6117977A (en) * 1996-04-24 2000-09-12 Genentech, Inc. Type C lectins
ZA973051B (en) * 1996-04-24 1998-10-12 Genentech Inc Type c lectins
US7744888B2 (en) * 2001-08-03 2010-06-29 Abgenomics Cooperatief U.A. Methods of modulating T cell or natural killer cell activity with anti-P-selectin glycoprotein ligand 1 antibodies

Also Published As

Publication number Publication date
RU2407539C2 (ru) 2010-12-27
IL174172A (en) 2011-12-29
UA91004C2 (uk) 2010-06-25
CA2538284C (en) 2015-10-20
TWI359024B (en) 2012-03-01
NO20061306L (no) 2006-06-14
AU2004273807B2 (en) 2011-06-09
IL174172A0 (en) 2006-08-01
EP1663290A2 (en) 2006-06-07
CA2538284A1 (en) 2005-03-31
ECSP066507A (es) 2006-10-10
CN1852730B (zh) 2012-05-30
KR101159140B1 (ko) 2012-06-22
AU2004273807A1 (en) 2005-03-31
JP5808879B2 (ja) 2015-11-10
ZA200602151B (en) 2013-08-28
EP1663290A4 (en) 2009-07-01
CN1852730A (zh) 2006-10-25
TW201012472A (en) 2010-04-01
TW200513262A (en) 2005-04-16
RU2006112399A (ru) 2006-08-10
KR20060088104A (ko) 2006-08-03
SG146670A1 (en) 2008-10-30
JP2007533618A (ja) 2007-11-22
NZ546203A (en) 2009-05-31

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Legal Events

Date Code Title Description
B25A Requested transfer of rights approved

Owner name: ABGENOMICS COOEPERATIEF U.A. (NL)

Free format text: TRANSFERIDO DE: ABGENOMICS CORPORATION

B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]
B25G Requested change of headquarter approved

Owner name: ABGENOMICS COOEPERATIEF U.A. (NL)

B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL