BRPI0415355A - triarilimidazóis - Google Patents

triarilimidazóis

Info

Publication number
BRPI0415355A
BRPI0415355A BRPI0415355-3A BRPI0415355A BRPI0415355A BR PI0415355 A BRPI0415355 A BR PI0415355A BR PI0415355 A BRPI0415355 A BR PI0415355A BR PI0415355 A BRPI0415355 A BR PI0415355A
Authority
BR
Brazil
Prior art keywords
triarylimidazoles
cancer
triarilimidazois
compounds
treatment
Prior art date
Application number
BRPI0415355-3A
Other languages
English (en)
Inventor
Thomas Von Hirschheydt
Edgar Voss
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of BRPI0415355A publication Critical patent/BRPI0415355A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

"TRIARILIMIDAZóIS". Compostos da fórmula geral (I) são terapêuticos valiosos para o tratamento de câncer e doenças relacionadas com o câncer.
BRPI0415355-3A 2003-10-16 2004-10-15 triarilimidazóis BRPI0415355A (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP03023633 2003-10-16
EP03026522 2003-11-18
PCT/EP2004/011600 WO2005040153A1 (en) 2003-10-16 2004-10-15 Novel triarylimidazoles

Publications (1)

Publication Number Publication Date
BRPI0415355A true BRPI0415355A (pt) 2006-12-12

Family

ID=34524706

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0415355-3A BRPI0415355A (pt) 2003-10-16 2004-10-15 triarilimidazóis

Country Status (12)

Country Link
US (1) US7144889B2 (pt)
EP (1) EP1675848A1 (pt)
JP (1) JP2007508345A (pt)
KR (1) KR100794948B1 (pt)
AR (1) AR046112A1 (pt)
AU (1) AU2004283846A1 (pt)
BR (1) BRPI0415355A (pt)
CA (1) CA2538131A1 (pt)
MX (1) MXPA06003699A (pt)
RU (1) RU2372346C2 (pt)
TW (1) TW200528444A (pt)
WO (1) WO2005040153A1 (pt)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7807832B2 (en) * 2005-07-28 2010-10-05 Janssen Pharmaceutica Nv Synthesis of 4/5-pyrimidinylimidazoles via sequential functionalization of 2,4-dichloropyrimidine
US7683060B2 (en) * 2006-08-07 2010-03-23 Incyte Corporation Triazolotriazines as kinase inhibitors
MX2009004426A (es) 2006-10-23 2009-08-12 Cephalon Inc Derivados biciclicos fusionados de 2,4-diaminopirimidina como inhibidores alk y c-met.
GEP20125658B (en) * 2006-11-22 2012-10-10 Incyte Corp Imidazotriazines and imidazo pyrimidines as kinase inhibitors
WO2009111644A2 (en) * 2008-03-05 2009-09-11 The Regents Of The University Of Michigan Compositions and methods for diagnosing and treating pancreatic cancer
SI2300455T1 (sl) 2008-05-21 2017-12-29 Incyte Holdings Corporation Soli 2-fluoro-n-metil-4-(7-(kinolin-6-il-metil)-imidazo(1,2-b)1,2,4) triazin-2-il)benzamid in postopki v zvezi z njihovo pripravo
MX2012008898A (es) 2010-02-03 2012-11-06 Incyte Corp Imidazo - [1, 2 - b] [1, 2, 4] triazinas como inhibidores de c - met.
WO2012084678A1 (en) 2010-12-23 2012-06-28 Syngenta Participations Ag Novel imidazoles useful as plant fungicides
MA52033A (fr) * 2014-08-13 2021-01-20 Nippon Soda Co Composé de diarylimidazole et agent de lutte antiparasitaire

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5656644A (en) 1994-07-20 1997-08-12 Smithkline Beecham Corporation Pyridyl imidazoles
ATE252094T1 (de) 1994-12-13 2003-11-15 Hoffmann La Roche Imidazol derivate mit proteinkinase, insbesondere egf-r tyrosinkinase, inhibierender wirkung
JP2002505690A (ja) * 1997-06-19 2002-02-19 スミスクライン・ビーチャム・コーポレイション 新規なアリールオキシピリミジン置換イミダゾール化合物
AU2023801A (en) 1999-12-17 2001-06-25 Mitsubishi Chemical Corporation Dihalopropenyloxybenzene derivatives and pesticides containing the same as the active ingredient
US6790852B2 (en) 2002-04-18 2004-09-14 Hoffmann-La Roche Inc. 2-(2,6-dichlorophenyl)-diarylimidazoles

Also Published As

Publication number Publication date
CA2538131A1 (en) 2005-05-06
US7144889B2 (en) 2006-12-05
US20050085473A1 (en) 2005-04-21
KR20060056400A (ko) 2006-05-24
AU2004283846A1 (en) 2005-05-06
RU2006116631A (ru) 2007-11-27
KR100794948B1 (ko) 2008-01-15
MXPA06003699A (es) 2006-06-05
AR046112A1 (es) 2005-11-23
WO2005040153A1 (en) 2005-05-06
EP1675848A1 (en) 2006-07-05
JP2007508345A (ja) 2007-04-05
TW200528444A (en) 2005-09-01
RU2372346C2 (ru) 2009-11-10

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Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B08F Application fees: application dismissed [chapter 8.6 patent gazette]

Free format text: REFERENTE A 7A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2158 DE 15/05/2012.