BRPI0415530A - uso de compostos orgánicos - Google Patents

uso de compostos orgánicos

Info

Publication number
BRPI0415530A
BRPI0415530A BRPI0415530-0A BRPI0415530A BRPI0415530A BR PI0415530 A BRPI0415530 A BR PI0415530A BR PI0415530 A BRPI0415530 A BR PI0415530A BR PI0415530 A BRPI0415530 A BR PI0415530A
Authority
BR
Brazil
Prior art keywords
organic compounds
benazapril
ccb
mortality
administering
Prior art date
Application number
BRPI0415530-0A
Other languages
English (en)
Inventor
Ken Jamerson
Malcolm Mac Nab
Bertram Pitt
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of BRPI0415530A publication Critical patent/BRPI0415530A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/401—Proline; Derivatives thereof, e.g. captopril
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/455—Nicotinic acids, e.g. niacin; Derivatives thereof, e.g. esters, amides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/549—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame having two or more nitrogen atoms in the same ring, e.g. hydrochlorothiazide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Molecular Biology (AREA)
  • Hospice & Palliative Care (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Hydrogenated Pyridines (AREA)

Abstract

"USO DE COMPOSTOS ORGáNICOS". A presente invenção diz respeito a um método para reduzir morbidade e/ou mortalidade cardiovascular compreendendo administrar uma combinação compreendendo um inibidor de ACE e um CCB, especificamente benazapril e besilato de amiodipina.
BRPI0415530-0A 2003-10-20 2004-10-19 uso de compostos orgánicos BRPI0415530A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US51263403P 2003-10-20 2003-10-20
PCT/EP2004/011824 WO2005037278A2 (en) 2003-10-20 2004-10-19 Tbenazpril and amlodipine for reducing cardiovascular morbidity

Publications (1)

Publication Number Publication Date
BRPI0415530A true BRPI0415530A (pt) 2006-12-26

Family

ID=34465367

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0415530-0A BRPI0415530A (pt) 2003-10-20 2004-10-19 uso de compostos orgánicos

Country Status (19)

Country Link
US (2) US20060233876A1 (pt)
EP (1) EP1776115A2 (pt)
JP (1) JP2007511473A (pt)
KR (1) KR20060120126A (pt)
CN (1) CN101137367A (pt)
AU (1) AU2004281541B2 (pt)
BR (1) BRPI0415530A (pt)
CA (1) CA2542757A1 (pt)
IL (1) IL174927A0 (pt)
IS (1) IS8470A (pt)
MA (1) MA28108A1 (pt)
MX (1) MXPA06004369A (pt)
NO (1) NO20062236L (pt)
RU (1) RU2006117198A (pt)
SG (1) SG147456A1 (pt)
TN (1) TNSN06111A1 (pt)
TW (1) TW200524591A (pt)
WO (1) WO2005037278A2 (pt)
ZA (1) ZA200602994B (pt)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9940405B2 (en) 2011-04-05 2018-04-10 Beyondcore Holdings, Llc Automatically optimizing business process platforms
US10127130B2 (en) * 2005-03-18 2018-11-13 Salesforce.Com Identifying contributors that explain differences between a data set and a subset of the data set
US8158146B2 (en) 2005-09-28 2012-04-17 Teva Pharmaceutical Industries Ltd. Stable combinations of amlodipine besylate and benazepril hydrochloride
CN101985035A (zh) * 2009-07-14 2011-03-16 邬林祥 一种治疗高血压含培哚普利的复方制剂
SI2585051T2 (sl) 2010-06-23 2020-07-31 Krka, D.D., Novo Mesto Farmacevtske oralne odmerne oblike,ki obsegajo lerkanidipin in enalapril in njune farmacevtsko sprejemljive soli
US10796232B2 (en) 2011-12-04 2020-10-06 Salesforce.Com, Inc. Explaining differences between predicted outcomes and actual outcomes of a process
US10802687B2 (en) 2011-12-04 2020-10-13 Salesforce.Com, Inc. Displaying differences between different data sets of a process
CN102440993B (zh) * 2011-12-08 2013-04-17 扬子江药业集团广州海瑞药业有限公司 一种氨氯地平和贝那普利的药物组合物
BR112014014896A2 (pt) 2011-12-21 2017-06-13 Novartis Ag nova combinação
CN102688245A (zh) * 2012-06-11 2012-09-26 北京阜康仁生物制药科技有限公司 一种稳定的氨氯地平与贝那普利药用组合物及其制备方法
JP2014219945A (ja) * 2013-05-10 2014-11-20 富士通株式会社 治験情報出力装置、治験情報出力方法および治験情報出力プログラム
US20200111575A1 (en) * 2018-10-04 2020-04-09 Babylon Partners Limited Producing a multidimensional space data structure to perform survival analysis

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6162802A (en) * 1992-03-10 2000-12-19 Papa; Joseph Synergistic combination therapy using benazepril and amlodipine for the treatment of cardiovascular disorders and compositions therefor
EP0795327A1 (en) * 1996-03-13 1997-09-17 Pfizer Inc. Use of Amlodipine for the treatment and prophylaxis of congestive cardiac failure of non-ischaemic origin
JP2004516266A (ja) * 2000-12-18 2004-06-03 ノバルティス アクチエンゲゼルシャフト アムロジピンおよびベナゼブリルの治療的組み合わせ
PE20040468A1 (es) * 2002-05-17 2004-09-14 Novartis Ag Combinacion de compuestos organicos

Also Published As

Publication number Publication date
US20060233876A1 (en) 2006-10-19
NO20062236L (no) 2006-07-19
CN101137367A (zh) 2008-03-05
JP2007511473A (ja) 2007-05-10
US20080242659A1 (en) 2008-10-02
SG147456A1 (en) 2008-11-28
AU2004281541B2 (en) 2008-05-01
ZA200602994B (en) 2008-03-26
TNSN06111A1 (en) 2007-11-15
IL174927A0 (en) 2008-04-13
CA2542757A1 (en) 2005-04-28
TW200524591A (en) 2005-08-01
WO2005037278A2 (en) 2005-04-28
MXPA06004369A (es) 2006-06-14
MA28108A1 (fr) 2006-08-01
EP1776115A2 (en) 2007-04-25
IS8470A (is) 2006-05-16
KR20060120126A (ko) 2006-11-24
RU2006117198A (ru) 2007-12-10
WO2005037278A3 (en) 2007-05-10
AU2004281541A1 (en) 2005-04-28

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE AS 6A E 7A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2158 DE 15/05/2012.